Research ArticleArticle
Characterization of T-5 N-Oxide Formation as the First Highly Selective Measure of CYP3A5 Activity
Xiaohai Li, Valer Jeso, Scott Heyward, Gregory S. Walker, Raman Sharma, Glenn C. Micalizio and Michael D. Cameron
Drug Metabolism and Disposition March 2014, 42 (3) 334-342; DOI: https://doi.org/10.1124/dmd.113.054726
Xiaohai Li
Department of Molecular Therapeutics, Scripps Research Institute, Jupiter, Florida (M.D.C., X.L.); Celsis In Vitro Technologies, Baltimore Maryland (S.H.); Department of Chemistry, Dartmouth College, Hanover, New Hampshire (V.J., G.C.M.), Pharmacokinetics, Dynamics, and Metabolism Department, Pfizer Global Research and Development, Groton, Connecticut (G.S.W., R.S.)
Valer Jeso
Department of Molecular Therapeutics, Scripps Research Institute, Jupiter, Florida (M.D.C., X.L.); Celsis In Vitro Technologies, Baltimore Maryland (S.H.); Department of Chemistry, Dartmouth College, Hanover, New Hampshire (V.J., G.C.M.), Pharmacokinetics, Dynamics, and Metabolism Department, Pfizer Global Research and Development, Groton, Connecticut (G.S.W., R.S.)
Scott Heyward
Department of Molecular Therapeutics, Scripps Research Institute, Jupiter, Florida (M.D.C., X.L.); Celsis In Vitro Technologies, Baltimore Maryland (S.H.); Department of Chemistry, Dartmouth College, Hanover, New Hampshire (V.J., G.C.M.), Pharmacokinetics, Dynamics, and Metabolism Department, Pfizer Global Research and Development, Groton, Connecticut (G.S.W., R.S.)
Gregory S. Walker
Department of Molecular Therapeutics, Scripps Research Institute, Jupiter, Florida (M.D.C., X.L.); Celsis In Vitro Technologies, Baltimore Maryland (S.H.); Department of Chemistry, Dartmouth College, Hanover, New Hampshire (V.J., G.C.M.), Pharmacokinetics, Dynamics, and Metabolism Department, Pfizer Global Research and Development, Groton, Connecticut (G.S.W., R.S.)
Raman Sharma
Department of Molecular Therapeutics, Scripps Research Institute, Jupiter, Florida (M.D.C., X.L.); Celsis In Vitro Technologies, Baltimore Maryland (S.H.); Department of Chemistry, Dartmouth College, Hanover, New Hampshire (V.J., G.C.M.), Pharmacokinetics, Dynamics, and Metabolism Department, Pfizer Global Research and Development, Groton, Connecticut (G.S.W., R.S.)
Glenn C. Micalizio
Department of Molecular Therapeutics, Scripps Research Institute, Jupiter, Florida (M.D.C., X.L.); Celsis In Vitro Technologies, Baltimore Maryland (S.H.); Department of Chemistry, Dartmouth College, Hanover, New Hampshire (V.J., G.C.M.), Pharmacokinetics, Dynamics, and Metabolism Department, Pfizer Global Research and Development, Groton, Connecticut (G.S.W., R.S.)
Michael D. Cameron
Department of Molecular Therapeutics, Scripps Research Institute, Jupiter, Florida (M.D.C., X.L.); Celsis In Vitro Technologies, Baltimore Maryland (S.H.); Department of Chemistry, Dartmouth College, Hanover, New Hampshire (V.J., G.C.M.), Pharmacokinetics, Dynamics, and Metabolism Department, Pfizer Global Research and Development, Groton, Connecticut (G.S.W., R.S.)

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Research ArticleArticle
Selective CYP3A5 Marker Reaction
Xiaohai Li, Valer Jeso, Scott Heyward, Gregory S. Walker, Raman Sharma, Glenn C. Micalizio and Michael D. Cameron
Drug Metabolism and Disposition March 1, 2014, 42 (3) 334-342; DOI: https://doi.org/10.1124/dmd.113.054726
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