Research ArticleArticle
Expression and Characterization of Cynomolgus Monkey Cytochrome CYP3A4 in a Novel Human Embryonic Kidney Cell–Based Mammalian System
Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
Drug Metabolism and Disposition March 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491
Sindhuja Selvakumar
Pharmaceutical Candidate Optimization (P.B., M.S.) and Applied Biotechnology (Si.S., K.G., P.K., S.K., Sa.S.), Biocon Bristol-Myers Squibb Research and Development Center (BBRC), Syngene International Limited, Plot No. 2 & 3, Bommasandra IV Phase, Bangalore, India; Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S.); Bristol-Myers Squibb, Pennington, New Jersey (A.D.R.); and Bristol-Myers Squibb India Ltd. BBRC, Bangalore, India (M.R., S.M.)
Priyadeep Bhutani
Pharmaceutical Candidate Optimization (P.B., M.S.) and Applied Biotechnology (Si.S., K.G., P.K., S.K., Sa.S.), Biocon Bristol-Myers Squibb Research and Development Center (BBRC), Syngene International Limited, Plot No. 2 & 3, Bommasandra IV Phase, Bangalore, India; Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S.); Bristol-Myers Squibb, Pennington, New Jersey (A.D.R.); and Bristol-Myers Squibb India Ltd. BBRC, Bangalore, India (M.R., S.M.)
Kaushik Ghosh
Pharmaceutical Candidate Optimization (P.B., M.S.) and Applied Biotechnology (Si.S., K.G., P.K., S.K., Sa.S.), Biocon Bristol-Myers Squibb Research and Development Center (BBRC), Syngene International Limited, Plot No. 2 & 3, Bommasandra IV Phase, Bangalore, India; Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S.); Bristol-Myers Squibb, Pennington, New Jersey (A.D.R.); and Bristol-Myers Squibb India Ltd. BBRC, Bangalore, India (M.R., S.M.)
Prasad Krishnamurthy
Pharmaceutical Candidate Optimization (P.B., M.S.) and Applied Biotechnology (Si.S., K.G., P.K., S.K., Sa.S.), Biocon Bristol-Myers Squibb Research and Development Center (BBRC), Syngene International Limited, Plot No. 2 & 3, Bommasandra IV Phase, Bangalore, India; Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S.); Bristol-Myers Squibb, Pennington, New Jersey (A.D.R.); and Bristol-Myers Squibb India Ltd. BBRC, Bangalore, India (M.R., S.M.)
Sanjith Kallipatti
Pharmaceutical Candidate Optimization (P.B., M.S.) and Applied Biotechnology (Si.S., K.G., P.K., S.K., Sa.S.), Biocon Bristol-Myers Squibb Research and Development Center (BBRC), Syngene International Limited, Plot No. 2 & 3, Bommasandra IV Phase, Bangalore, India; Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S.); Bristol-Myers Squibb, Pennington, New Jersey (A.D.R.); and Bristol-Myers Squibb India Ltd. BBRC, Bangalore, India (M.R., S.M.)
Sabariya Selvam
Pharmaceutical Candidate Optimization (P.B., M.S.) and Applied Biotechnology (Si.S., K.G., P.K., S.K., Sa.S.), Biocon Bristol-Myers Squibb Research and Development Center (BBRC), Syngene International Limited, Plot No. 2 & 3, Bommasandra IV Phase, Bangalore, India; Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S.); Bristol-Myers Squibb, Pennington, New Jersey (A.D.R.); and Bristol-Myers Squibb India Ltd. BBRC, Bangalore, India (M.R., S.M.)
Manjunath Ramarao
Pharmaceutical Candidate Optimization (P.B., M.S.) and Applied Biotechnology (Si.S., K.G., P.K., S.K., Sa.S.), Biocon Bristol-Myers Squibb Research and Development Center (BBRC), Syngene International Limited, Plot No. 2 & 3, Bommasandra IV Phase, Bangalore, India; Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S.); Bristol-Myers Squibb, Pennington, New Jersey (A.D.R.); and Bristol-Myers Squibb India Ltd. BBRC, Bangalore, India (M.R., S.M.)
Sandhya Mandlekar
Pharmaceutical Candidate Optimization (P.B., M.S.) and Applied Biotechnology (Si.S., K.G., P.K., S.K., Sa.S.), Biocon Bristol-Myers Squibb Research and Development Center (BBRC), Syngene International Limited, Plot No. 2 & 3, Bommasandra IV Phase, Bangalore, India; Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S.); Bristol-Myers Squibb, Pennington, New Jersey (A.D.R.); and Bristol-Myers Squibb India Ltd. BBRC, Bangalore, India (M.R., S.M.)
Michael W. Sinz
Pharmaceutical Candidate Optimization (P.B., M.S.) and Applied Biotechnology (Si.S., K.G., P.K., S.K., Sa.S.), Biocon Bristol-Myers Squibb Research and Development Center (BBRC), Syngene International Limited, Plot No. 2 & 3, Bommasandra IV Phase, Bangalore, India; Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S.); Bristol-Myers Squibb, Pennington, New Jersey (A.D.R.); and Bristol-Myers Squibb India Ltd. BBRC, Bangalore, India (M.R., S.M.)
A. David Rodrigues
Pharmaceutical Candidate Optimization (P.B., M.S.) and Applied Biotechnology (Si.S., K.G., P.K., S.K., Sa.S.), Biocon Bristol-Myers Squibb Research and Development Center (BBRC), Syngene International Limited, Plot No. 2 & 3, Bommasandra IV Phase, Bangalore, India; Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S.); Bristol-Myers Squibb, Pennington, New Jersey (A.D.R.); and Bristol-Myers Squibb India Ltd. BBRC, Bangalore, India (M.R., S.M.)
Murali Subramanian
Pharmaceutical Candidate Optimization (P.B., M.S.) and Applied Biotechnology (Si.S., K.G., P.K., S.K., Sa.S.), Biocon Bristol-Myers Squibb Research and Development Center (BBRC), Syngene International Limited, Plot No. 2 & 3, Bommasandra IV Phase, Bangalore, India; Bristol-Myers Squibb, Wallingford, Connecticut (M.W.S.); Bristol-Myers Squibb, Pennington, New Jersey (A.D.R.); and Bristol-Myers Squibb India Ltd. BBRC, Bangalore, India (M.R., S.M.)
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Research ArticleArticle
Expression and Characterization of Cynomolgus CYP3A4
Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
Drug Metabolism and Disposition March 1, 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491
Research ArticleArticle
Expression and Characterization of Cynomolgus CYP3A4
Sindhuja Selvakumar, Priyadeep Bhutani, Kaushik Ghosh, Prasad Krishnamurthy, Sanjith Kallipatti, Sabariya Selvam, Manjunath Ramarao, Sandhya Mandlekar, Michael W. Sinz, A. David Rodrigues and Murali Subramanian
Drug Metabolism and Disposition March 1, 2014, 42 (3) 369-376; DOI: https://doi.org/10.1124/dmd.113.055491
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