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Research ArticleArticle

Disposition and Metabolism of Darapladib, a Lipoprotein-Associated Phospholipase A2 Inhibitor, in Humans

Mehul Dave, Mike Nash, Graeme C. Young, Harma Ellens, Mindy H. Magee, Andrew D. Roberts, Maxine A. Taylor, Robert W. Greenhill and Gary W. Boyle
Drug Metabolism and Disposition March 2014, 42 (3) 415-430; DOI: https://doi.org/10.1124/dmd.113.054486

Article Information

vol. 42 no. 3 415-430
DOI 
https://doi.org/10.1124/dmd.113.054486
PubMed 
24378325
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 6, 2013
  • Accepted December 30, 2013
  • Published online February 4, 2014.

Article Versions

Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Mehul Dave,
  2. Mike Nash,
  3. Graeme C. Young,
  4. Harma Ellens,
  5. Mindy H. Magee,
  6. Andrew D. Roberts,
  7. Maxine A. Taylor,
  8. Robert W. Greenhill, and
  9. Gary W. Boyle
  1. Department of Drug Metabolism and Pharmacokinetics (M.D., M.N., G.C.Y., A.D.R., M.A.T., G.W.B.) and Department of Safety Assessment (R.W.G.), GlaxoSmithKline Research & Development, Ware, United Kingdom, and Department of Drug Metabolism and Pharmacokinetics (H.E.) and Clinical Pharmacology, Modeling and Simulation (M.H.M.), GlaxoSmithKline Research & Development, Upper Merion, Philadelphia
  1. Address correspondence to:
    Gary W. Boyle, DMPK, GlaxoSmithKline, Ware, UK. E-mail: Gary.W.Boyle{at}gsk.com
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Research ArticleArticle

Disposition and Metabolism of Darapladib in Humans

Mehul Dave, Mike Nash, Graeme C. Young, Harma Ellens, Mindy H. Magee, Andrew D. Roberts, Maxine A. Taylor, Robert W. Greenhill and Gary W. Boyle
Drug Metabolism and Disposition March 1, 2014, 42 (3) 415-430; DOI: https://doi.org/10.1124/dmd.113.054486
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