Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn
Research ArticleArticle

Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors

Gunilla Englund, Patrik Lundquist, Cristine Skogastierna, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius, Tommy B. Andersson and Denis Projean
Drug Metabolism and Disposition March 2014, 42 (3) 441-447; DOI: https://doi.org/10.1124/dmd.113.054932
Gunilla Englund
CNS and Pain Innovative Medicines DMPK, AstraZeneca R&D, Södertälje (G.E., P.L., C.S., J.J., J.H., L.A.); Cardiovascular and Metabolic Diseases Innovative Medicines DMPK, AstraZeneca R&D, Mölndal (P.L., T.B.A., D.P.); Department of Pharmacy, Uppsala University, Uppsala (P.L.); and Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm (T.B.A.), Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Patrik Lundquist
CNS and Pain Innovative Medicines DMPK, AstraZeneca R&D, Södertälje (G.E., P.L., C.S., J.J., J.H., L.A.); Cardiovascular and Metabolic Diseases Innovative Medicines DMPK, AstraZeneca R&D, Mölndal (P.L., T.B.A., D.P.); Department of Pharmacy, Uppsala University, Uppsala (P.L.); and Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm (T.B.A.), Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Cristine Skogastierna
CNS and Pain Innovative Medicines DMPK, AstraZeneca R&D, Södertälje (G.E., P.L., C.S., J.J., J.H., L.A.); Cardiovascular and Metabolic Diseases Innovative Medicines DMPK, AstraZeneca R&D, Mölndal (P.L., T.B.A., D.P.); Department of Pharmacy, Uppsala University, Uppsala (P.L.); and Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm (T.B.A.), Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jenny Johansson
CNS and Pain Innovative Medicines DMPK, AstraZeneca R&D, Södertälje (G.E., P.L., C.S., J.J., J.H., L.A.); Cardiovascular and Metabolic Diseases Innovative Medicines DMPK, AstraZeneca R&D, Mölndal (P.L., T.B.A., D.P.); Department of Pharmacy, Uppsala University, Uppsala (P.L.); and Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm (T.B.A.), Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Janet Hoogstraate
CNS and Pain Innovative Medicines DMPK, AstraZeneca R&D, Södertälje (G.E., P.L., C.S., J.J., J.H., L.A.); Cardiovascular and Metabolic Diseases Innovative Medicines DMPK, AstraZeneca R&D, Mölndal (P.L., T.B.A., D.P.); Department of Pharmacy, Uppsala University, Uppsala (P.L.); and Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm (T.B.A.), Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Lovisa Afzelius
CNS and Pain Innovative Medicines DMPK, AstraZeneca R&D, Södertälje (G.E., P.L., C.S., J.J., J.H., L.A.); Cardiovascular and Metabolic Diseases Innovative Medicines DMPK, AstraZeneca R&D, Mölndal (P.L., T.B.A., D.P.); Department of Pharmacy, Uppsala University, Uppsala (P.L.); and Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm (T.B.A.), Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Tommy B. Andersson
CNS and Pain Innovative Medicines DMPK, AstraZeneca R&D, Södertälje (G.E., P.L., C.S., J.J., J.H., L.A.); Cardiovascular and Metabolic Diseases Innovative Medicines DMPK, AstraZeneca R&D, Mölndal (P.L., T.B.A., D.P.); Department of Pharmacy, Uppsala University, Uppsala (P.L.); and Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm (T.B.A.), Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Denis Projean
CNS and Pain Innovative Medicines DMPK, AstraZeneca R&D, Södertälje (G.E., P.L., C.S., J.J., J.H., L.A.); Cardiovascular and Metabolic Diseases Innovative Medicines DMPK, AstraZeneca R&D, Mölndal (P.L., T.B.A., D.P.); Department of Pharmacy, Uppsala University, Uppsala (P.L.); and Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm (T.B.A.), Sweden
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

Article Information

vol. 42 no. 3 441-447
DOI 
https://doi.org/10.1124/dmd.113.054932
PubMed 
24396142

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 17, 2013
  • Accepted January 6, 2014
  • Published online February 12, 2014.

Article Versions

  • Earlier version (January 6, 2014 - 08:05).
  • Earlier version (January 6, 2014 - 08:51).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Gunilla Englund,
  2. Patrik Lundquist,
  3. Cristine Skogastierna,
  4. Jenny Johansson,
  5. Janet Hoogstraate,
  6. Lovisa Afzelius,
  7. Tommy B. Andersson, and
  8. Denis Projean
  1. CNS and Pain Innovative Medicines DMPK, AstraZeneca R&D, Södertälje (G.E., P.L., C.S., J.J., J.H., L.A.); Cardiovascular and Metabolic Diseases Innovative Medicines DMPK, AstraZeneca R&D, Mölndal (P.L., T.B.A., D.P.); Department of Pharmacy, Uppsala University, Uppsala (P.L.); and Section of Pharmacogenetics, Department of Physiology and Pharmacology, Karolinska Institutet, Stockholm (T.B.A.), Sweden
  1. Address correspondence to:
    Tommy B. Andersson, Cardiovascular and Metabolic Diseases Innovative Medicines DMPK, AstraZeneca R&D, Pepparedsleden 1, SE-431 83 Mölndal, Sweden. E-mail: tommy.b.andersson{at}astrazeneca.com
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: January 2014 to March 2021

AbstractFullPdf
Jan 20143992243
Feb 201461039146
Mar 201431127106
Apr 20141982463
May 2014911837
Jun 201465729
Jul 2014481525
Aug 2014341015
Sep 201438812
Oct 2014802121
Nov 2014511022
Dec 201452714
Jan 2015541119
Feb 201527617
Mar 2015313442
Apr 2015382326
May 2015452531
Jun 2015322522
Jul 2015342119
Aug 2015371519
Sep 2015251612
Oct 2015301820
Nov 2015241427
Dec 2015181217
Jan 2016261222
Feb 2016141721
Mar 2016311727
Apr 2016471424
May 2016311823
Jun 2016171235
Jul 2016251529
Aug 2016272031
Sep 2016161416
Oct 201641414
Nov 201643032
Dec 201603822
Jan 201714134
Feb 201744120
Mar 201732411
Apr 201721918
May 201711525
Jun 201713126
Jul 201701923
Aug 201712414
Sep 201723518
Oct 201714133
Nov 201723325
Dec 20171198
Jan 201822215
Feb 201812227
Mar 201822919
Apr 201801615
May 201802922
Jun 201803119
Jul 201821412
Aug 201811911
Sep 201802213
Oct 201803421
Nov 201837412
Dec 201812645
Jan 201966610
Feb 2019662928
Mar 20194418
Apr 20192246
May 20191735
Jun 201916519
Jul 20192412
Aug 20193747
Sep 20192713
Oct 20192057
Nov 201929311
Dec 2019111610
Jan 20201105
Feb 20201795
Mar 20202935
Apr 20204425
May 20201523
Jun 20202823
Jul 20202499
Aug 2020824
Sep 2020930
Oct 20202977
Nov 20201157
Dec 20202777
Jan 202135188
Feb 2021281111
Mar 20211400

PreviousNext
Back to top

In this issue

Drug Metabolism and Disposition: 42 (3)
Drug Metabolism and Disposition
Vol. 42, Issue 3
1 Mar 2014
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Drug Metabolism & Disposition article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Cytochrome P450 Inhibitory Properties of Common Efflux Transporter Inhibitors
(Your Name) has forwarded a page to you from Drug Metabolism & Disposition
(Your Name) thought you would be interested in this article in Drug Metabolism & Disposition.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleArticle

P450 Inhibition by Efflux Transporter Inhibitors

Gunilla Englund, Patrik Lundquist, Cristine Skogastierna, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius, Tommy B. Andersson and Denis Projean
Drug Metabolism and Disposition March 1, 2014, 42 (3) 441-447; DOI: https://doi.org/10.1124/dmd.113.054932

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero
Share
Research ArticleArticle

P450 Inhibition by Efflux Transporter Inhibitors

Gunilla Englund, Patrik Lundquist, Cristine Skogastierna, Jenny Johansson, Janet Hoogstraate, Lovisa Afzelius, Tommy B. Andersson and Denis Projean
Drug Metabolism and Disposition March 1, 2014, 42 (3) 441-447; DOI: https://doi.org/10.1124/dmd.113.054932
del.icio.us logo Digg logo Reddit logo Twitter logo CiteULike logo Facebook logo Google logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Deoxycholate Oxidation is Predictive of CYP3A Activity
  • Retroconversion of PQ and its N-oxide metabolites
  • HNF4A-AS1 regulates CYPs via histone modifications
Show more Articles

Similar Articles

  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2021 by the American Society for Pharmacology and Experimental Therapeutics