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Drug Metabolism & Disposition

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    • Current Issue
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Index by author

April 01, 2014; Volume 42,Issue 4
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Achour, Brahim

    1. You have access
      Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics
      Brahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632
  2. Arai, Yuki

    1. You have access
      Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044

B

  1. Barber, Jill

    1. You have access
      Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics
      Brahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632
  2. Barr, John T.

    1. You have access
      Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
  3. Bebawy, Mary

    1. You have access
      Inhibition of the Multidrug Resistance P-Glycoprotein: Time for a Change of Strategy?
      Richard Callaghan, Frederick Luk and Mary Bebawy
      Drug Metabolism and Disposition April 2014, 42 (4) 623-631; DOI: https://doi.org/10.1124/dmd.113.056176
  4. Beduneau, Arnaud

    1. You have access
      Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
  5. Berry, Loren M.

    1. You have access
      Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809
  6. Bittner, Florian

    1. You have access
      Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
  7. Boerger, Cornelia

    1. You have access
      Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
  8. Brouwer, Kim L. R.

    1. You have access
      Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304

C

  1. Callaghan, Richard

    1. You have access
      Inhibition of the Multidrug Resistance P-Glycoprotein: Time for a Change of Strategy?
      Richard Callaghan, Frederick Luk and Mary Bebawy
      Drug Metabolism and Disposition April 2014, 42 (4) 623-631; DOI: https://doi.org/10.1124/dmd.113.056176
  2. Canet, Mark J.

    1. You have access
      Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996
  3. Cao, Yang

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
  4. Cascorbi, Ingolf

    1. You have access
      Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
  5. Chan, Gary L.

    1. You have access
      The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
  6. Chaudhry, Amarjit S.

    1. You have access
      Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
  7. Chen, Jianzhong

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
  8. Chen, Minjun

    1. You have access
      High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
  9. Chen, Qingmei

    1. You have access
      N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
  10. Chen, Shifeng

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
  11. Chen, Xiaoyan

    1. You have access
      Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218
  12. Cheong, Jonathan

    1. You have access
      Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats
      Xingrong Liu, Jonathan Cheong, Xiao Ding and Gauri Deshmukh
      Drug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590
  13. Cherrington, Nathan J.

    1. You have access
      Selective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in Mice
      Matthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. Morgan
      Drug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525
    2. You have access
      Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996
  14. Choughule, Kanika V.

    1. You have access
      Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
  15. Chu, Xiaoyan

    1. You have access
      Understanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug Development
      Maciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra Galetin
      Drug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558
  16. Chung, Hye Jin

    1. You have access
      Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
  17. Clarke, John D.

    1. You have access
      Selective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in Mice
      Matthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. Morgan
      Drug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525
    2. You have access
      Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996
  18. Claudel, Thierry

    1. You have access
      The Role of Canalicular ABC Transporters in Cholestasis
      Frans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael Trauner
      Drug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358
  19. Clement, Bernd

    1. You have access
      Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
  20. Colletti, Adria

    1. You have access
      Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809
  21. Cressman, Alex M.

    1. You have access
      Malaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant Mice
      Alex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-Miller
      Drug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983
  22. Cuperus, Frans J. C.

    1. You have access
      The Role of Canalicular ABC Transporters in Cholestasis
      Frans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael Trauner
      Drug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358
  23. Cvijic, Mary Ellen

    1. You have access
      Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205

D

  1. Damme, Katja

    1. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
  2. Deng, Yiqun

    1. You have access
      N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
  3. Deshmukh, Gauri

    1. You have access
      Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats
      Xingrong Liu, Jonathan Cheong, Xiao Ding and Gauri Deshmukh
      Drug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590
  4. Diao, Xingxing

    1. You have access
      Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218
  5. Ding, Xiao

    1. You have access
      Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats
      Xingrong Liu, Jonathan Cheong, Xiao Ding and Gauri Deshmukh
      Drug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590
  6. Dowty, Martin E.

    1. You have access
      The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
  7. Dzierlenga, Anika L.

    1. You have access
      Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996

E

  1. El-Kabbani, Ossama

    1. You have access
      Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
  2. Elkin, Lisa L.

    1. You have access
      Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
  3. Endo, Satoshi

    1. You have access
      Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044

F

  1. Ferslew, Brian C.

    1. You have access
      Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
  2. Fischer, James

    1. You have access
      Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
  3. Fischer, Liam

    1. You have access
      Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
  4. Fischer, Thomas

    1. You have access
      Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
  5. Fukami, Tatsuki

    1. You have access
      Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184

G

  1. Galetin, Aleksandra

    1. You have access
      Understanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug Development
      Maciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra Galetin
      Drug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558
  2. Gallo, James M.

    1. You have access
      The Effect of ABCG2 and ABCC4 on the Pharmacokinetics of Methotrexate in the Brain
      Ramola Sane, Shu-Pei Wu, Rong Zhang and James M. Gallo
      Drug Metabolism and Disposition April 2014, 42 (4) 537-540; DOI: https://doi.org/10.1124/dmd.113.055228
  3. Gautherot, Julien

    1. You have access
      The Role of Canalicular ABC Transporters in Cholestasis
      Frans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael Trauner
      Drug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358
  4. Geng, Xingchao

    1. You have access
      High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
  5. Gonzalez, Frank J.

    1. You have access
      Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
  6. Gromand, Jessica

    1. You have access
      Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
  7. Guo, Zitao

    1. You have access
      Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218

H

  1. Halilbasic, Emina

    1. You have access
      The Role of Canalicular ABC Transporters in Cholestasis
      Frans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael Trauner
      Drug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358
  2. Hara, Akira

    1. You have access
      Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
  3. Hardwick, Rhiannon N.

    1. You have access
      Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996
  4. Havemeyer, Antje

    1. You have access
      Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
  5. He, Guangzhao

    1. You have access
      Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
  6. Heer, Dominik

    1. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
  7. Hegedüs, Csilla

    1. You have access
      Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding Sites
      Ágnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-Laczka
      Drug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731
  8. Horikawa, Masato

    1. You have access
      Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
  9. Hou, Tingjun

    1. You have access
      Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
  10. Hou, Zhanjun

    1. You have access
      The Major Facilitative Folate Transporters Solute Carrier 19A1 and Solute Carrier 46A1: Biology and Role in Antifolate Chemotherapy of Cancer
      Larry H. Matherly, Mike R. Wilson and Zhanjun Hou
      Drug Metabolism and Disposition April 2014, 42 (4) 632-649; DOI: https://doi.org/10.1124/dmd.113.055723
  11. Hu, Haihong

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

I

  1. Ikari, Akira

    1. You have access
      Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
  2. Ilic, Katarina

    1. You have access
      High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
  3. Imamura, Yuichiro

    1. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
  4. Imaoka, Tomoki

    1. You have access
      Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
  5. Ishiwata, Norihisa

    1. You have access
      Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
  6. Ito, Yusuke

    1. You have access
      Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
  7. Izumi, Takashi

    1. You have access
      Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
    2. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

J

  1. Jeong, Hyunyoung

    1. You have access
      Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
    2. You have access
      17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor α
      Wei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178
  2. Jiang, Huidi

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
  3. Jones, Jeffrey P.

    1. You have access
      Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
  4. Jones, Nathan R.

    1. You have access
      UGT2B Gene Expression Analysis in Multiple Tobacco Carcinogen-Targeted Tissues
      Nathan R. Jones and Philip Lazarus
      Drug Metabolism and Disposition April 2014, 42 (4) 529-536; DOI: https://doi.org/10.1124/dmd.113.054718
  5. Joswig-Jones, Carolyn A.

    1. You have access
      Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

K

  1. Kain, Kevin C.

    1. You have access
      Malaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant Mice
      Alex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-Miller
      Drug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983
  2. Kariya, Motoki

    1. You have access
      Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
  3. Kato, Yukio

    1. You have access
      Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
  4. Keppler, Dietrich

    1. You have access
      The Roles of MRP2, MRP3, OATP1B1, and OATP1B3 in Conjugated Hyperbilirubinemia
      Dietrich Keppler
      Drug Metabolism and Disposition April 2014, 42 (4) 561-565; DOI: https://doi.org/10.1124/dmd.113.055772
  5. Kim, Heesue

    1. You have access
      17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor α
      Wei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178
  6. Kitade, Yukio

    1. You have access
      Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
  7. Köck, Kathleen

    1. You have access
      Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
  8. Koh, Kwi Hye

    1. You have access
      17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor α
      Wei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178
  9. Krishnaswami, Sriram

    1. You have access
      The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
  10. Krolikowski, Paul

    1. You have access
      Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809
  11. Kumagai, Yuji

    1. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
  12. Kunze, Thomas

    1. You have access
      Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
  13. Kurihara, Atsushi

    1. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
  14. Kurokawa, Takaya

    1. You have access
      Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
  15. Kusuhara, Hiroyuki

    1. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

L

  1. Lai, Yurong

    1. You have access
      Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
  2. Lake, April D.

    1. You have access
      Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996
  3. Lamprecht, Alf

    1. You have access
      Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
  4. Lazarus, Philip

    1. You have access
      UGT2B Gene Expression Analysis in Multiple Tobacco Carcinogen-Targeted Tissues
      Nathan R. Jones and Philip Lazarus
      Drug Metabolism and Disposition April 2014, 42 (4) 529-536; DOI: https://doi.org/10.1124/dmd.113.054718
  5. Lee, Jin Kyung

    1. You have access
      Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
  6. Li, Jiajun

    1. You have access
      Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
  7. Li, Wei

    1. You have access
      17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor α
      Wei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178
  8. Lin, Jinyan

    1. You have access
      The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
  9. Liu, Jingzhou

    1. You have access
      Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809
  10. Liu, Xingrong

    1. You have access
      Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats
      Xingrong Liu, Jonathan Cheong, Xiao Ding and Gauri Deshmukh
      Drug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590
  11. Lou, Yan

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
  12. Luk, Frederick

    1. You have access
      Inhibition of the Multidrug Resistance P-Glycoprotein: Time for a Change of Strategy?
      Richard Callaghan, Frederick Luk and Mary Bebawy
      Drug Metabolism and Disposition April 2014, 42 (4) 623-631; DOI: https://doi.org/10.1124/dmd.113.056176

M

  1. Maeda, Kazuya

    1. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
  2. Masumoto, Hiroshi

    1. You have access
      Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
  3. Masuo, Yusuke

    1. You have access
      Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
  4. Matherly, Larry H.

    1. You have access
      The Major Facilitative Folate Transporters Solute Carrier 19A1 and Solute Carrier 46A1: Biology and Role in Antifolate Chemotherapy of Cancer
      Larry H. Matherly, Mike R. Wilson and Zhanjun Hou
      Drug Metabolism and Disposition April 2014, 42 (4) 632-649; DOI: https://doi.org/10.1124/dmd.113.055723
  5. Matsubara, Kazuki

    1. You have access
      Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
  6. Matsunaga, Toshiyuki

    1. You have access
      Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
  7. McDonald, Chloe R.

    1. You have access
      Malaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant Mice
      Alex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-Miller
      Drug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983
  8. Mendel, Ralf-Rainer

    1. You have access
      Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
  9. Merrell, Matthew D.

    1. You have access
      Selective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in Mice
      Matthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. Morgan
      Drug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525
  10. Mikkaichi, Tsuyoshi

    1. You have access
      Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
  11. Montesinos, Rita Nieto

    1. You have access
      Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
  12. Morgan, Edward T.

    1. You have access
      Selective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in Mice
      Matthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. Morgan
      Drug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525
  13. Moulari, Brice

    1. You have access
      Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
  14. Mu, Peiqiang

    1. You have access
      N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
  15. Müllhaupt, Beat

    1. You have access
      The Role of Organic Anion Transporters in Diagnosing Liver Diseases by Magnetic Resonance Imaging
      Catherine M. Pastor, Beat Müllhaupt and Bruno Stieger
      Drug Metabolism and Disposition April 2014, 42 (4) 675-684; DOI: https://doi.org/10.1124/dmd.113.055707
  16. Murayama, Nobuyuki

    1. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

N

  1. Nakajima, Miki

    1. You have access
      Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
  2. Nakamichi, Noritaka

    1. You have access
      Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
  3. Nepal, Sahadev

    1. You have access
      Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
  4. Netterberg, Ida

    1. You have access
      Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
  5. Ning, Miaoran

    1. You have access
      17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor α
      Wei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178
  6. Nyagode, Beatrice A.

    1. You have access
      Selective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in Mice
      Matthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. Morgan
      Drug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525

O

  1. Okudaira, Noriko

    1. You have access
      Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
    2. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
  2. Ott, Gudrun

    1. You have access
      Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
  3. Özvegy-Laczka, Csilla

    1. You have access
      Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding Sites
      Ágnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-Laczka
      Drug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731

P

  1. Paine, Mary F.

    1. You have access
      Understanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug Development
      Maciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra Galetin
      Drug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558
  2. Pan, Peichen

    1. You have access
      Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
  3. Pang, Xiaoyan

    1. You have access
      Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218
  4. Pastor, Catherine M.

    1. You have access
      The Role of Organic Anion Transporters in Diagnosing Liver Diseases by Magnetic Resonance Imaging
      Catherine M. Pastor, Beat Müllhaupt and Bruno Stieger
      Drug Metabolism and Disposition April 2014, 42 (4) 675-684; DOI: https://doi.org/10.1124/dmd.113.055707
  5. Pellequer, Yann

    1. You have access
      Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
  6. Piquette-Miller, Micheline

    1. You have access
      Malaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant Mice
      Alex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-Miller
      Drug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983
  7. Polli, Joseph W.

    1. You have access
      Understanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug Development
      Maciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra Galetin
      Drug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558
  8. Prakash, Chandra

    1. You have access
      The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
  9. Pu, Jianbin

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

Q

  1. Qi, Huixin

    1. You have access
      Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793

R

  1. Reichmann, Debora

    1. You have access
      Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
  2. Rodrigues, A. David

    1. You have access
      Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
  3. Rostami-Hodjegan, Amin

    1. You have access
      Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics
      Brahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632
  4. Rozehnal, Veronika

    1. You have access
      Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
  5. Russell, Matthew R.

    1. You have access
      Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics
      Brahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632
  6. Ryder, Tim F.

    1. You have access
      The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940

S

  1. Sane, Ramola

    1. You have access
      The Effect of ABCG2 and ABCC4 on the Pharmacokinetics of Methotrexate in the Brain
      Ramola Sane, Shu-Pei Wu, Rong Zhang and James M. Gallo
      Drug Metabolism and Disposition April 2014, 42 (4) 537-540; DOI: https://doi.org/10.1124/dmd.113.055228
  2. Sarkadi, Balázs

    1. You have access
      Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding Sites
      Ágnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-Laczka
      Drug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731
  3. Sato, Ren

    1. You have access
      Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
  4. Schuetz, Erin G.

    1. You have access
      Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
  5. Schuetz, John D.

    1. You have access
      The Role of Transporters in Toxicity and Disease
      John D. Schuetz, Peter W. Swaan and Donald J. Tweedie
      Drug Metabolism and Disposition April 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539
  6. Shimizu, Mai

    1. You have access
      Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
  7. Shimizu, Takuya

    1. You have access
      Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
  8. Silver, Karlee

    1. You have access
      Malaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant Mice
      Alex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-Miller
      Drug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983
  9. Soars, Matthew G.

    1. You have access
      Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
  10. Sparreboom, Alex

    1. You have access
      Uptake Carriers and Oncology Drug Safety
      Jason A. Sprowl and Alex Sparreboom
      Drug Metabolism and Disposition April 2014, 42 (4) 611-622; DOI: https://doi.org/10.1124/dmd.113.055806
  11. Sprowl, Jason A.

    1. You have access
      Uptake Carriers and Oncology Drug Safety
      Jason A. Sprowl and Alex Sparreboom
      Drug Metabolism and Disposition April 2014, 42 (4) 611-622; DOI: https://doi.org/10.1124/dmd.113.055806
  12. Stewart, Paul W.

    1. You have access
      Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
  13. Stieger, Bruno

    1. You have access
      The Role of Organic Anion Transporters in Diagnosing Liver Diseases by Magnetic Resonance Imaging
      Catherine M. Pastor, Beat Müllhaupt and Bruno Stieger
      Drug Metabolism and Disposition April 2014, 42 (4) 675-684; DOI: https://doi.org/10.1124/dmd.113.055707
  14. Strom, Stephen C.

    1. You have access
      Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
  15. Sugiura, Tomoko

    1. You have access
      Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
  16. Sugiyama, Yuichi

    1. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
  17. Swaan, Peter W.

    1. You have access
      The Role of Transporters in Toxicity and Disease
      John D. Schuetz, Peter W. Swaan and Donald J. Tweedie
      Drug Metabolism and Disposition April 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539
    2. You have access
      Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304

T

  1. Tajima, Kazuo

    1. You have access
      Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
  2. Takeuchi, Kazuya

    1. You have access
      Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
  3. Tang, Xianqing

    1. You have access
      N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
  4. Teffera, Yohannes

    1. You have access
      Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809
  5. Telbisz, Ágnes

    1. You have access
      Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding Sites
      Ágnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-Laczka
      Drug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731
  6. Thummel, Kenneth E.

    1. You have access
      Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
  7. Tong, Weida

    1. You have access
      High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
  8. Trauner, Michael

    1. You have access
      The Role of Canalicular ABC Transporters in Cholestasis
      Frans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael Trauner
      Drug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358
  9. Tsuruya, Yuri

    1. You have access
      6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
  10. Tweedie, Donald J.

    1. You have access
      The Role of Transporters in Toxicity and Disease
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      Drug Metabolism and Disposition April 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539

U

  1. Urban, Thomas J.

    1. You have access
      Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304

V

  1. Váradi, András

    1. You have access
      Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding Sites
      Ágnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-Laczka
      Drug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731
  2. Vaz, Alfin

    1. You have access
      The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940

W

  1. Walker, Gregory S.

    1. You have access
      The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
  2. Wang, Bingshun

    1. You have access
      High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
  3. Wang, Lijuan

    1. You have access
      N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
  4. Wang, Meiyu

    1. You have access
      Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
  5. Wang, Weiwei

    1. You have access
      The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
  6. Wang, Yedong

    1. You have access
      Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
  7. Wang, Yufan

    1. You have access
      N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
  8. Wilson, Mike R.

    1. You have access
      The Major Facilitative Folate Transporters Solute Carrier 19A1 and Solute Carrier 46A1: Biology and Role in Antifolate Chemotherapy of Cancer
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      Drug Metabolism and Disposition April 2014, 42 (4) 632-649; DOI: https://doi.org/10.1124/dmd.113.055723
  9. Wong, Timothy

    1. You have access
      Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
  10. Wu, Kaixin

    1. You have access
      N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
  11. Wu, Shu-Pei

    1. You have access
      The Effect of ABCG2 and ABCC4 on the Pharmacokinetics of Methotrexate in the Brain
      Ramola Sane, Shu-Pei Wu, Rong Zhang and James M. Gallo
      Drug Metabolism and Disposition April 2014, 42 (4) 537-540; DOI: https://doi.org/10.1124/dmd.113.055228

X

  1. Xie, Cen

    1. You have access
      Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218
  2. Xu, Ming

    1. You have access
      N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418

Y

  1. Yamano, Shigeru

    1. You have access
      Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
  2. Yang, Kyunghee

    1. You have access
      Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
  3. Yokoi, Tsuyoshi

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      Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
  4. Yoshigae, Yasushi

    1. You have access
      Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
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      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
  5. Yu, Ke

    1. You have access
      High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
  6. Yu, Lushan

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

Z

  1. Zamek-Gliszczynski, Maciej J.

    1. You have access
      Understanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug Development
      Maciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra Galetin
      Drug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558
  2. Zeng, Su

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
  3. Zhang, Hongjian

    1. You have access
      Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
  4. Zhang, Jie

    1. You have access
      High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
  5. Zhang, Rong

    1. You have access
      The Effect of ABCG2 and ABCC4 on the Pharmacokinetics of Methotrexate in the Brain
      Ramola Sane, Shu-Pei Wu, Rong Zhang and James M. Gallo
      Drug Metabolism and Disposition April 2014, 42 (4) 537-540; DOI: https://doi.org/10.1124/dmd.113.055228
  6. Zhang, Xia

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
  7. Zhao, Zhiyang

    1. You have access
      Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809
  8. Zheng, Ming

    1. You have access
      N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
  9. Zheng, Yuanming

    1. You have access
      N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
  10. Zhong, Dafang

    1. You have access
      Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218
  11. Zhou, Quan

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
  12. Zientek, Michael

    1. You have access
      Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
  13. Zuo, Minjuan

    1. You have access
      Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
  14. Zvyaga, Tatyana

    1. You have access
      Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
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Drug Metabolism and Disposition: 42 (4)
Drug Metabolism and Disposition
Vol. 42, Issue 4
1 Apr 2014
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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