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Index by author

April 01, 2014; Volume 42,Issue 4

A

  1. Achour, Brahim

    1. Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics
      Brahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632

  2. Arai, Yuki

    1. Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044

B

  1. Barber, Jill

    1. Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics
      Brahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632

  2. Barr, John T.

    1. Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

  3. Bebawy, Mary

    1. Inhibition of the Multidrug Resistance P-Glycoprotein: Time for a Change of Strategy?
      Richard Callaghan, Frederick Luk and Mary Bebawy
      Drug Metabolism and Disposition April 2014, 42 (4) 623-631; DOI: https://doi.org/10.1124/dmd.113.056176

  4. Beduneau, Arnaud

    1. Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566

  5. Berry, Loren M.

    1. Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809

  6. Bittner, Florian

    1. Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202

  7. Boerger, Cornelia

    1. Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202

  8. Brouwer, Kim L. R.

    1. Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304

C

  1. Callaghan, Richard

    1. Inhibition of the Multidrug Resistance P-Glycoprotein: Time for a Change of Strategy?
      Richard Callaghan, Frederick Luk and Mary Bebawy
      Drug Metabolism and Disposition April 2014, 42 (4) 623-631; DOI: https://doi.org/10.1124/dmd.113.056176

  2. Canet, Mark J.

    1. Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996

  3. Cao, Yang

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

  4. Cascorbi, Ingolf

    1. Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202

  5. Chan, Gary L.

    1. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940

  6. Chaudhry, Amarjit S.

    1. Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

  7. Chen, Jianzhong

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

  8. Chen, Minjun

    1. High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267

  9. Chen, Qingmei

    1. N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418

  10. Chen, Shifeng

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

  11. Chen, Xiaoyan

    1. Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218

  12. Cheong, Jonathan

    1. Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats
      Xingrong Liu, Jonathan Cheong, Xiao Ding and Gauri Deshmukh
      Drug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590

  13. Cherrington, Nathan J.

    1. Selective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in Mice
      Matthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. Morgan
      Drug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525
    2. Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996

  14. Choughule, Kanika V.

    1. Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

  15. Chu, Xiaoyan

    1. Understanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug Development
      Maciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra Galetin
      Drug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558

  16. Chung, Hye Jin

    1. Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384

  17. Clarke, John D.

    1. Selective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in Mice
      Matthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. Morgan
      Drug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525
    2. Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996

  18. Claudel, Thierry

    1. The Role of Canalicular ABC Transporters in Cholestasis
      Frans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael Trauner
      Drug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358

  19. Clement, Bernd

    1. Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202

  20. Colletti, Adria

    1. Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809

  21. Cressman, Alex M.

    1. Malaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant Mice
      Alex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-Miller
      Drug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983

  22. Cuperus, Frans J. C.

    1. The Role of Canalicular ABC Transporters in Cholestasis
      Frans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael Trauner
      Drug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358

  23. Cvijic, Mary Ellen

    1. Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205

D

  1. Damme, Katja

    1. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

  2. Deng, Yiqun

    1. N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418

  3. Deshmukh, Gauri

    1. Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats
      Xingrong Liu, Jonathan Cheong, Xiao Ding and Gauri Deshmukh
      Drug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590

  4. Diao, Xingxing

    1. Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218

  5. Ding, Xiao

    1. Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats
      Xingrong Liu, Jonathan Cheong, Xiao Ding and Gauri Deshmukh
      Drug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590

  6. Dowty, Martin E.

    1. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940

  7. Dzierlenga, Anika L.

    1. Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996

E

  1. El-Kabbani, Ossama

    1. Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044

  2. Elkin, Lisa L.

    1. Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205

  3. Endo, Satoshi

    1. Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044

F

  1. Ferslew, Brian C.

    1. Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304

  2. Fischer, James

    1. Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384

  3. Fischer, Liam

    1. Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384

  4. Fischer, Thomas

    1. Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866

  5. Fukami, Tatsuki

    1. Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184

G

  1. Galetin, Aleksandra

    1. Understanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug Development
      Maciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra Galetin
      Drug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558

  2. Gallo, James M.

    1. The Effect of ABCG2 and ABCC4 on the Pharmacokinetics of Methotrexate in the Brain
      Ramola Sane, Shu-Pei Wu, Rong Zhang and James M. Gallo
      Drug Metabolism and Disposition April 2014, 42 (4) 537-540; DOI: https://doi.org/10.1124/dmd.113.055228

  3. Gautherot, Julien

    1. The Role of Canalicular ABC Transporters in Cholestasis
      Frans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael Trauner
      Drug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358

  4. Geng, Xingchao

    1. High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267

  5. Gonzalez, Frank J.

    1. Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384

  6. Gromand, Jessica

    1. Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566

  7. Guo, Zitao

    1. Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218

H

  1. Halilbasic, Emina

    1. The Role of Canalicular ABC Transporters in Cholestasis
      Frans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael Trauner
      Drug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358

  2. Hara, Akira

    1. Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044

  3. Hardwick, Rhiannon N.

    1. Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996

  4. Havemeyer, Antje

    1. Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202

  5. He, Guangzhao

    1. Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793

  6. Heer, Dominik

    1. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

  7. Hegedüs, Csilla

    1. Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding Sites
      Ágnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-Laczka
      Drug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731

  8. Horikawa, Masato

    1. Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767

  9. Hou, Tingjun

    1. Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793

  10. Hou, Zhanjun

    1. The Major Facilitative Folate Transporters Solute Carrier 19A1 and Solute Carrier 46A1: Biology and Role in Antifolate Chemotherapy of Cancer
      Larry H. Matherly, Mike R. Wilson and Zhanjun Hou
      Drug Metabolism and Disposition April 2014, 42 (4) 632-649; DOI: https://doi.org/10.1124/dmd.113.055723

  11. Hu, Haihong

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

I

  1. Ikari, Akira

    1. Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044

  2. Ilic, Katarina

    1. High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267

  3. Imamura, Yuichiro

    1. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

  4. Imaoka, Tomoki

    1. Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866

  5. Ishiwata, Norihisa

    1. Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767

  6. Ito, Yusuke

    1. Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184

  7. Izumi, Takashi

    1. Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
    2. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

J

  1. Jeong, Hyunyoung

    1. Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
    2. 17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor α
      Wei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178

  2. Jiang, Huidi

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

  3. Jones, Jeffrey P.

    1. Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

  4. Jones, Nathan R.

    1. UGT2B Gene Expression Analysis in Multiple Tobacco Carcinogen-Targeted Tissues
      Nathan R. Jones and Philip Lazarus
      Drug Metabolism and Disposition April 2014, 42 (4) 529-536; DOI: https://doi.org/10.1124/dmd.113.054718

  5. Joswig-Jones, Carolyn A.

    1. Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

K

  1. Kain, Kevin C.

    1. Malaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant Mice
      Alex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-Miller
      Drug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983

  2. Kariya, Motoki

    1. Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184

  3. Kato, Yukio

    1. Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767

  4. Keppler, Dietrich

    1. The Roles of MRP2, MRP3, OATP1B1, and OATP1B3 in Conjugated Hyperbilirubinemia
      Dietrich Keppler
      Drug Metabolism and Disposition April 2014, 42 (4) 561-565; DOI: https://doi.org/10.1124/dmd.113.055772

  5. Kim, Heesue

    1. 17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor α
      Wei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178

  6. Kitade, Yukio

    1. Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044

  7. Köck, Kathleen

    1. Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304

  8. Koh, Kwi Hye

    1. 17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor α
      Wei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178

  9. Krishnaswami, Sriram

    1. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940

  10. Krolikowski, Paul

    1. Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809

  11. Kumagai, Yuji

    1. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

  12. Kunze, Thomas

    1. Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202

  13. Kurihara, Atsushi

    1. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

  14. Kurokawa, Takaya

    1. Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184

  15. Kusuhara, Hiroyuki

    1. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

L

  1. Lai, Yurong

    1. Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205

  2. Lake, April D.

    1. Modeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent Models
      Mark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. Cherrington
      Drug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996

  3. Lamprecht, Alf

    1. Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566

  4. Lazarus, Philip

    1. UGT2B Gene Expression Analysis in Multiple Tobacco Carcinogen-Targeted Tissues
      Nathan R. Jones and Philip Lazarus
      Drug Metabolism and Disposition April 2014, 42 (4) 529-536; DOI: https://doi.org/10.1124/dmd.113.054718

  5. Lee, Jin Kyung

    1. Human Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human Hepatocytes
      Jin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384

  6. Li, Jiajun

    1. Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793

  7. Li, Wei

    1. 17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor α
      Wei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178

  8. Lin, Jinyan

    1. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940

  9. Liu, Jingzhou

    1. Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809

  10. Liu, Xingrong

    1. Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats
      Xingrong Liu, Jonathan Cheong, Xiao Ding and Gauri Deshmukh
      Drug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590

  11. Lou, Yan

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

  12. Luk, Frederick

    1. Inhibition of the Multidrug Resistance P-Glycoprotein: Time for a Change of Strategy?
      Richard Callaghan, Frederick Luk and Mary Bebawy
      Drug Metabolism and Disposition April 2014, 42 (4) 623-631; DOI: https://doi.org/10.1124/dmd.113.056176

M

  1. Maeda, Kazuya

    1. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

  2. Masumoto, Hiroshi

    1. Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866

  3. Masuo, Yusuke

    1. Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767

  4. Matherly, Larry H.

    1. The Major Facilitative Folate Transporters Solute Carrier 19A1 and Solute Carrier 46A1: Biology and Role in Antifolate Chemotherapy of Cancer
      Larry H. Matherly, Mike R. Wilson and Zhanjun Hou
      Drug Metabolism and Disposition April 2014, 42 (4) 632-649; DOI: https://doi.org/10.1124/dmd.113.055723

  5. Matsubara, Kazuki

    1. Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767

  6. Matsunaga, Toshiyuki

    1. Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044

  7. McDonald, Chloe R.

    1. Malaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant Mice
      Alex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-Miller
      Drug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983

  8. Mendel, Ralf-Rainer

    1. Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202

  9. Merrell, Matthew D.

    1. Selective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in Mice
      Matthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. Morgan
      Drug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525

  10. Mikkaichi, Tsuyoshi

    1. Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866

  11. Montesinos, Rita Nieto

    1. Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566

  12. Morgan, Edward T.

    1. Selective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in Mice
      Matthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. Morgan
      Drug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525

  13. Moulari, Brice

    1. Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566

  14. Mu, Peiqiang

    1. N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418

  15. Müllhaupt, Beat

    1. The Role of Organic Anion Transporters in Diagnosing Liver Diseases by Magnetic Resonance Imaging
      Catherine M. Pastor, Beat Müllhaupt and Bruno Stieger
      Drug Metabolism and Disposition April 2014, 42 (4) 675-684; DOI: https://doi.org/10.1124/dmd.113.055707

  16. Murayama, Nobuyuki

    1. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

N

  1. Nakajima, Miki

    1. Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184

  2. Nakamichi, Noritaka

    1. Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767

  3. Nepal, Sahadev

    1. Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

  4. Netterberg, Ida

    1. Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304

  5. Ning, Miaoran

    1. 17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor α
      Wei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung Jeong
      Drug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178

  6. Nyagode, Beatrice A.

    1. Selective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in Mice
      Matthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. Morgan
      Drug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525

O

  1. Okudaira, Noriko

    1. Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
    2. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

  2. Ott, Gudrun

    1. Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202

  3. Özvegy-Laczka, Csilla

    1. Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding Sites
      Ágnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-Laczka
      Drug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731

P

  1. Paine, Mary F.

    1. Understanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug Development
      Maciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra Galetin
      Drug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558

  2. Pan, Peichen

    1. Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793

  3. Pang, Xiaoyan

    1. Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218

  4. Pastor, Catherine M.

    1. The Role of Organic Anion Transporters in Diagnosing Liver Diseases by Magnetic Resonance Imaging
      Catherine M. Pastor, Beat Müllhaupt and Bruno Stieger
      Drug Metabolism and Disposition April 2014, 42 (4) 675-684; DOI: https://doi.org/10.1124/dmd.113.055707

  5. Pellequer, Yann

    1. Coadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain Distribution
      Rita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann Pellequer
      Drug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566

  6. Piquette-Miller, Micheline

    1. Malaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant Mice
      Alex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-Miller
      Drug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983

  7. Polli, Joseph W.

    1. Understanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug Development
      Maciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra Galetin
      Drug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558

  8. Prakash, Chandra

    1. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940

  9. Pu, Jianbin

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

Q

  1. Qi, Huixin

    1. Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793

R

  1. Reichmann, Debora

    1. Functional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy Caucasians
      Gudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje Havemeyer
      Drug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202

  2. Rodrigues, A. David

    1. Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205

  3. Rostami-Hodjegan, Amin

    1. Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics
      Brahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632

  4. Rozehnal, Veronika

    1. Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866

  5. Russell, Matthew R.

    1. Simultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted Proteomics
      Brahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632

  6. Ryder, Tim F.

    1. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940

S

  1. Sane, Ramola

    1. The Effect of ABCG2 and ABCC4 on the Pharmacokinetics of Methotrexate in the Brain
      Ramola Sane, Shu-Pei Wu, Rong Zhang and James M. Gallo
      Drug Metabolism and Disposition April 2014, 42 (4) 537-540; DOI: https://doi.org/10.1124/dmd.113.055228

  2. Sarkadi, Balázs

    1. Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding Sites
      Ágnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-Laczka
      Drug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731

  3. Sato, Ren

    1. Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767

  4. Schuetz, Erin G.

    1. Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

  5. Schuetz, John D.

    1. The Role of Transporters in Toxicity and Disease
      John D. Schuetz, Peter W. Swaan and Donald J. Tweedie
      Drug Metabolism and Disposition April 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539

  6. Shimizu, Mai

    1. Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184

  7. Shimizu, Takuya

    1. Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767

  8. Silver, Karlee

    1. Malaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant Mice
      Alex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-Miller
      Drug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983

  9. Soars, Matthew G.

    1. Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205

  10. Sparreboom, Alex

    1. Uptake Carriers and Oncology Drug Safety
      Jason A. Sprowl and Alex Sparreboom
      Drug Metabolism and Disposition April 2014, 42 (4) 611-622; DOI: https://doi.org/10.1124/dmd.113.055806

  11. Sprowl, Jason A.

    1. Uptake Carriers and Oncology Drug Safety
      Jason A. Sprowl and Alex Sparreboom
      Drug Metabolism and Disposition April 2014, 42 (4) 611-622; DOI: https://doi.org/10.1124/dmd.113.055806

  12. Stewart, Paul W.

    1. Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304

  13. Stieger, Bruno

    1. The Role of Organic Anion Transporters in Diagnosing Liver Diseases by Magnetic Resonance Imaging
      Catherine M. Pastor, Beat Müllhaupt and Bruno Stieger
      Drug Metabolism and Disposition April 2014, 42 (4) 675-684; DOI: https://doi.org/10.1124/dmd.113.055707

  14. Strom, Stephen C.

    1. Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

  15. Sugiura, Tomoko

    1. Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767

  16. Sugiyama, Yuichi

    1. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

  17. Swaan, Peter W.

    1. The Role of Transporters in Toxicity and Disease
      John D. Schuetz, Peter W. Swaan and Donald J. Tweedie
      Drug Metabolism and Disposition April 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539
    2. Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304

T

  1. Tajima, Kazuo

    1. Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044

  2. Takeuchi, Kazuya

    1. Interaction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in Humans
      Kazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio Kato
      Drug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767

  3. Tang, Xianqing

    1. N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418

  4. Teffera, Yohannes

    1. Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809

  5. Telbisz, Ágnes

    1. Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding Sites
      Ágnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-Laczka
      Drug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731

  6. Thummel, Kenneth E.

    1. Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

  7. Tong, Weida

    1. High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267

  8. Trauner, Michael

    1. The Role of Canalicular ABC Transporters in Cholestasis
      Frans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael Trauner
      Drug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358

  9. Tsuruya, Yuri

    1. 6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy Subjects
      Yuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475

  10. Tweedie, Donald J.

    1. The Role of Transporters in Toxicity and Disease
      John D. Schuetz, Peter W. Swaan and Donald J. Tweedie
      Drug Metabolism and Disposition April 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539

U

  1. Urban, Thomas J.

    1. Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304

V

  1. Váradi, András

    1. Regulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding Sites
      Ágnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-Laczka
      Drug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731

  2. Vaz, Alfin

    1. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940

W

  1. Walker, Gregory S.

    1. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940

  2. Wang, Bingshun

    1. High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267

  3. Wang, Lijuan

    1. N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418

  4. Wang, Meiyu

    1. Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793

  5. Wang, Weiwei

    1. The Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in Humans
      Martin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra Prakash
      Drug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940

  6. Wang, Yedong

    1. Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793

  7. Wang, Yufan

    1. N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418

  8. Wilson, Mike R.

    1. The Major Facilitative Folate Transporters Solute Carrier 19A1 and Solute Carrier 46A1: Biology and Role in Antifolate Chemotherapy of Cancer
      Larry H. Matherly, Mike R. Wilson and Zhanjun Hou
      Drug Metabolism and Disposition April 2014, 42 (4) 632-649; DOI: https://doi.org/10.1124/dmd.113.055723

  9. Wong, Timothy

    1. Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

  10. Wu, Kaixin

    1. N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418

  11. Wu, Shu-Pei

    1. The Effect of ABCG2 and ABCC4 on the Pharmacokinetics of Methotrexate in the Brain
      Ramola Sane, Shu-Pei Wu, Rong Zhang and James M. Gallo
      Drug Metabolism and Disposition April 2014, 42 (4) 537-540; DOI: https://doi.org/10.1124/dmd.113.055228

X

  1. Xie, Cen

    1. Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218

  2. Xu, Ming

    1. N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418

Y

  1. Yamano, Shigeru

    1. Cloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone Reductases
      Satoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio Kitade
      Drug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044

  2. Yang, Kyunghee

    1. Risk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4
      Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. Brouwer
      Drug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304

  3. Yokoi, Tsuyoshi

    1. Indiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human Liver
      Mai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184

  4. Yoshigae, Yasushi

    1. Edoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s Disposition
      Tsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi Izumi
      Drug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866

  5. Yu, Ke

    1. High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267

  6. Yu, Lushan

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

Z

  1. Zamek-Gliszczynski, Maciej J.

    1. Understanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug Development
      Maciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra Galetin
      Drug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558

  2. Zeng, Su

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

  3. Zhang, Hongjian

    1. Pathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction Potentials
      Yedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian Zhang
      Drug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793

  4. Zhang, Jie

    1. High Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver Injury
      Ke Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida Tong
      Drug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267

  5. Zhang, Rong

    1. The Effect of ABCG2 and ABCC4 on the Pharmacokinetics of Methotrexate in the Brain
      Ramola Sane, Shu-Pei Wu, Rong Zhang and James M. Gallo
      Drug Metabolism and Disposition April 2014, 42 (4) 537-540; DOI: https://doi.org/10.1124/dmd.113.055228

  6. Zhang, Xia

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

  7. Zhao, Zhiyang

    1. Species Difference in Glucuronidation Formation Kinetics with a Selective mTOR Inhibitor
      Loren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes Teffera
      Drug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809

  8. Zheng, Ming

    1. N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418

  9. Zheng, Yuanming

    1. N-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1
      Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun Deng
      Drug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418

  10. Zhong, Dafang

    1. Bioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1
      Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218

  11. Zhou, Quan

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

  12. Zientek, Michael

    1. Why Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?Graphic
      John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. Jones
      Drug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374

  13. Zuo, Minjuan

    1. Hepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. Root
      Lushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su Zeng
      Drug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962

  14. Zvyaga, Tatyana

    1. Drug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export Pump
      A. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. Soars
      Drug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
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