Index by author
April 01, 2014; Volume 42,Issue 4
A
Achour, Brahim
- You have accessSimultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted ProteomicsBrahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-HodjeganDrug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632
Arai, Yuki
- You have accessCloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone ReductasesSatoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio KitadeDrug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
B
Barber, Jill
- You have accessSimultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted ProteomicsBrahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-HodjeganDrug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632
Barr, John T.
- You have accessWhy Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. JonesDrug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
Bebawy, Mary
- You have accessInhibition of the Multidrug Resistance P-Glycoprotein: Time for a Change of Strategy?Richard Callaghan, Frederick Luk and Mary BebawyDrug Metabolism and Disposition April 2014, 42 (4) 623-631; DOI: https://doi.org/10.1124/dmd.113.056176
Beduneau, Arnaud
- You have accessCoadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain DistributionRita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann PellequerDrug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
Berry, Loren M.
- You have accessSpecies Difference in Glucuronidation Formation Kinetics with a Selective mTOR InhibitorLoren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes TefferaDrug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809
Bittner, Florian
- You have accessFunctional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy CaucasiansGudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje HavemeyerDrug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
Boerger, Cornelia
- You have accessFunctional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy CaucasiansGudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje HavemeyerDrug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
Brouwer, Kim L. R.
- You have accessRisk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. BrouwerDrug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
C
Callaghan, Richard
- You have accessInhibition of the Multidrug Resistance P-Glycoprotein: Time for a Change of Strategy?Richard Callaghan, Frederick Luk and Mary BebawyDrug Metabolism and Disposition April 2014, 42 (4) 623-631; DOI: https://doi.org/10.1124/dmd.113.056176
Canet, Mark J.
- You have accessModeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent ModelsMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. CherringtonDrug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996
Cao, Yang
- You have accessHepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. RootLushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su ZengDrug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
Cascorbi, Ingolf
- You have accessFunctional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy CaucasiansGudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje HavemeyerDrug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
Chan, Gary L.
- You have accessThe Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in HumansMartin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra PrakashDrug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
Chaudhry, Amarjit S.
- You have accessWhy Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. JonesDrug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
Chen, Jianzhong
- You have accessHepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. RootLushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su ZengDrug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
Chen, Minjun
- You have accessHigh Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver InjuryKe Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida TongDrug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
Chen, Qingmei
- You have accessN-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun DengDrug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
Chen, Shifeng
- You have accessHepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. RootLushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su ZengDrug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
Chen, Xiaoyan
- You have accessBioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218
Cheong, Jonathan
- You have accessUse of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout RatsXingrong Liu, Jonathan Cheong, Xiao Ding and Gauri DeshmukhDrug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590
Cherrington, Nathan J.
- You have accessSelective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in MiceMatthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. MorganDrug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525
- You have accessModeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent ModelsMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. CherringtonDrug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996
Choughule, Kanika V.
- You have accessWhy Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. JonesDrug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
Chu, Xiaoyan
- You have accessUnderstanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug DevelopmentMaciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra GaletinDrug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558
Chung, Hye Jin
- You have accessHuman Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human HepatocytesJin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung JeongDrug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
Clarke, John D.
- You have accessSelective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in MiceMatthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. MorganDrug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525
- You have accessModeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent ModelsMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. CherringtonDrug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996
Claudel, Thierry
- You have accessThe Role of Canalicular ABC Transporters in CholestasisFrans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael TraunerDrug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358
Clement, Bernd
- You have accessFunctional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy CaucasiansGudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje HavemeyerDrug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
Colletti, Adria
- You have accessSpecies Difference in Glucuronidation Formation Kinetics with a Selective mTOR InhibitorLoren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes TefferaDrug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809
Cressman, Alex M.
- You have accessMalaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant MiceAlex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-MillerDrug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983
Cuperus, Frans J. C.
- You have accessThe Role of Canalicular ABC Transporters in CholestasisFrans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael TraunerDrug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358
Cvijic, Mary Ellen
- You have accessDrug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export PumpA. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. SoarsDrug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
D
Damme, Katja
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
Deng, Yiqun
- You have accessN-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun DengDrug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
Deshmukh, Gauri
- You have accessUse of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout RatsXingrong Liu, Jonathan Cheong, Xiao Ding and Gauri DeshmukhDrug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590
Diao, Xingxing
- You have accessBioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218
Ding, Xiao
- You have accessUse of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout RatsXingrong Liu, Jonathan Cheong, Xiao Ding and Gauri DeshmukhDrug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590
Dowty, Martin E.
- You have accessThe Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in HumansMartin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra PrakashDrug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
Dzierlenga, Anika L.
- You have accessModeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent ModelsMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. CherringtonDrug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996
E
El-Kabbani, Ossama
- You have accessCloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone ReductasesSatoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio KitadeDrug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
Elkin, Lisa L.
- You have accessDrug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export PumpA. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. SoarsDrug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
Endo, Satoshi
- You have accessCloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone ReductasesSatoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio KitadeDrug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
F
Ferslew, Brian C.
- You have accessRisk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. BrouwerDrug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
Fischer, James
- You have accessHuman Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human HepatocytesJin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung JeongDrug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
Fischer, Liam
- You have accessHuman Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human HepatocytesJin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung JeongDrug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
Fischer, Thomas
- You have accessEdoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s DispositionTsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
Fukami, Tatsuki
- You have accessIndiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human LiverMai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
G
Galetin, Aleksandra
- You have accessUnderstanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug DevelopmentMaciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra GaletinDrug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558
Gallo, James M.
- You have accessThe Effect of ABCG2 and ABCC4 on the Pharmacokinetics of Methotrexate in the BrainRamola Sane, Shu-Pei Wu, Rong Zhang and James M. GalloDrug Metabolism and Disposition April 2014, 42 (4) 537-540; DOI: https://doi.org/10.1124/dmd.113.055228
Gautherot, Julien
- You have accessThe Role of Canalicular ABC Transporters in CholestasisFrans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael TraunerDrug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358
Geng, Xingchao
- You have accessHigh Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver InjuryKe Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida TongDrug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
Gonzalez, Frank J.
- You have accessHuman Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human HepatocytesJin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung JeongDrug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
Gromand, Jessica
- You have accessCoadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain DistributionRita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann PellequerDrug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
Guo, Zitao
- You have accessBioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218
H
Halilbasic, Emina
- You have accessThe Role of Canalicular ABC Transporters in CholestasisFrans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael TraunerDrug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358
Hara, Akira
- You have accessCloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone ReductasesSatoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio KitadeDrug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
Hardwick, Rhiannon N.
- You have accessModeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent ModelsMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. CherringtonDrug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996
Havemeyer, Antje
- You have accessFunctional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy CaucasiansGudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje HavemeyerDrug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
He, Guangzhao
- You have accessPathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction PotentialsYedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian ZhangDrug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
Heer, Dominik
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
Hegedüs, Csilla
- You have accessRegulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding SitesÁgnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-LaczkaDrug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731
Horikawa, Masato
- You have accessInteraction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in HumansKazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio KatoDrug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
Hou, Tingjun
- You have accessPathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction PotentialsYedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian ZhangDrug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
Hou, Zhanjun
- You have accessThe Major Facilitative Folate Transporters Solute Carrier 19A1 and Solute Carrier 46A1: Biology and Role in Antifolate Chemotherapy of CancerLarry H. Matherly, Mike R. Wilson and Zhanjun HouDrug Metabolism and Disposition April 2014, 42 (4) 632-649; DOI: https://doi.org/10.1124/dmd.113.055723
Hu, Haihong
- You have accessHepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. RootLushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su ZengDrug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
I
Ikari, Akira
- You have accessCloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone ReductasesSatoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio KitadeDrug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
Ilic, Katarina
- You have accessHigh Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver InjuryKe Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida TongDrug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
Imamura, Yuichiro
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
Imaoka, Tomoki
- You have accessEdoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s DispositionTsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
Ishiwata, Norihisa
- You have accessInteraction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in HumansKazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio KatoDrug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
Ito, Yusuke
- You have accessIndiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human LiverMai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
Izumi, Takashi
- You have accessEdoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s DispositionTsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
J
Jeong, Hyunyoung
- You have accessHuman Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human HepatocytesJin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung JeongDrug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
- You have access17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor αWei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung JeongDrug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178
Jiang, Huidi
- You have accessHepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. RootLushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su ZengDrug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
Jones, Jeffrey P.
- You have accessWhy Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. JonesDrug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
Jones, Nathan R.
- You have accessUGT2B Gene Expression Analysis in Multiple Tobacco Carcinogen-Targeted TissuesNathan R. Jones and Philip LazarusDrug Metabolism and Disposition April 2014, 42 (4) 529-536; DOI: https://doi.org/10.1124/dmd.113.054718
Joswig-Jones, Carolyn A.
- You have accessWhy Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. JonesDrug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
K
Kain, Kevin C.
- You have accessMalaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant MiceAlex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-MillerDrug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983
Kariya, Motoki
- You have accessIndiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human LiverMai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
Kato, Yukio
- You have accessInteraction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in HumansKazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio KatoDrug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
Keppler, Dietrich
- You have accessThe Roles of MRP2, MRP3, OATP1B1, and OATP1B3 in Conjugated HyperbilirubinemiaDietrich KepplerDrug Metabolism and Disposition April 2014, 42 (4) 561-565; DOI: https://doi.org/10.1124/dmd.113.055772
Kim, Heesue
- You have access17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor αWei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung JeongDrug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178
Kitade, Yukio
- You have accessCloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone ReductasesSatoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio KitadeDrug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
Köck, Kathleen
- You have accessRisk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. BrouwerDrug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
Koh, Kwi Hye
- You have access17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor αWei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung JeongDrug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178
Krishnaswami, Sriram
- You have accessThe Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in HumansMartin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra PrakashDrug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
Krolikowski, Paul
- You have accessSpecies Difference in Glucuronidation Formation Kinetics with a Selective mTOR InhibitorLoren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes TefferaDrug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809
Kumagai, Yuji
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
Kunze, Thomas
- You have accessFunctional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy CaucasiansGudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje HavemeyerDrug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
Kurihara, Atsushi
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
Kurokawa, Takaya
- You have accessIndiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human LiverMai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
Kusuhara, Hiroyuki
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
L
Lai, Yurong
- You have accessDrug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export PumpA. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. SoarsDrug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
Lake, April D.
- You have accessModeling Human Nonalcoholic Steatohepatitis-Associated Changes in Drug Transporter Expression Using Experimental Rodent ModelsMark J. Canet, Rhiannon N. Hardwick, April D. Lake, Anika L. Dzierlenga, John D. Clarke and Nathan J. CherringtonDrug Metabolism and Disposition April 2014, 42 (4) 586-595; DOI: https://doi.org/10.1124/dmd.113.055996
Lamprecht, Alf
- You have accessCoadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain DistributionRita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann PellequerDrug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
Lazarus, Philip
- You have accessUGT2B Gene Expression Analysis in Multiple Tobacco Carcinogen-Targeted TissuesNathan R. Jones and Philip LazarusDrug Metabolism and Disposition April 2014, 42 (4) 529-536; DOI: https://doi.org/10.1124/dmd.113.054718
Lee, Jin Kyung
- You have accessHuman Placental Lactogen Induces CYP2E1 Expression via PI 3-Kinase Pathway in Female Human HepatocytesJin Kyung Lee, Hye Jin Chung, Liam Fischer, James Fischer, Frank J. Gonzalez and Hyunyoung JeongDrug Metabolism and Disposition April 2014, 42 (4) 492-499; DOI: https://doi.org/10.1124/dmd.113.055384
Li, Jiajun
- You have accessPathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction PotentialsYedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian ZhangDrug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
Li, Wei
- You have access17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor αWei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung JeongDrug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178
Lin, Jinyan
- You have accessThe Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in HumansMartin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra PrakashDrug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
Liu, Jingzhou
- You have accessSpecies Difference in Glucuronidation Formation Kinetics with a Selective mTOR InhibitorLoren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes TefferaDrug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809
Liu, Xingrong
- You have accessUse of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout RatsXingrong Liu, Jonathan Cheong, Xiao Ding and Gauri DeshmukhDrug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590
Lou, Yan
- You have accessHepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. RootLushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su ZengDrug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
Luk, Frederick
- You have accessInhibition of the Multidrug Resistance P-Glycoprotein: Time for a Change of Strategy?Richard Callaghan, Frederick Luk and Mary BebawyDrug Metabolism and Disposition April 2014, 42 (4) 623-631; DOI: https://doi.org/10.1124/dmd.113.056176
M
Maeda, Kazuya
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
Masumoto, Hiroshi
- You have accessEdoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s DispositionTsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
Masuo, Yusuke
- You have accessInteraction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in HumansKazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio KatoDrug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
Matherly, Larry H.
- You have accessThe Major Facilitative Folate Transporters Solute Carrier 19A1 and Solute Carrier 46A1: Biology and Role in Antifolate Chemotherapy of CancerLarry H. Matherly, Mike R. Wilson and Zhanjun HouDrug Metabolism and Disposition April 2014, 42 (4) 632-649; DOI: https://doi.org/10.1124/dmd.113.055723
Matsubara, Kazuki
- You have accessInteraction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in HumansKazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio KatoDrug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
Matsunaga, Toshiyuki
- You have accessCloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone ReductasesSatoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio KitadeDrug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
McDonald, Chloe R.
- You have accessMalaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant MiceAlex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-MillerDrug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983
Mendel, Ralf-Rainer
- You have accessFunctional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy CaucasiansGudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje HavemeyerDrug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
Merrell, Matthew D.
- You have accessSelective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in MiceMatthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. MorganDrug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525
Mikkaichi, Tsuyoshi
- You have accessEdoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s DispositionTsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
Montesinos, Rita Nieto
- You have accessCoadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain DistributionRita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann PellequerDrug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
Morgan, Edward T.
- You have accessSelective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in MiceMatthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. MorganDrug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525
Moulari, Brice
- You have accessCoadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain DistributionRita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann PellequerDrug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
Mu, Peiqiang
- You have accessN-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun DengDrug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
Müllhaupt, Beat
- You have accessThe Role of Organic Anion Transporters in Diagnosing Liver Diseases by Magnetic Resonance ImagingCatherine M. Pastor, Beat Müllhaupt and Bruno StiegerDrug Metabolism and Disposition April 2014, 42 (4) 675-684; DOI: https://doi.org/10.1124/dmd.113.055707
Murayama, Nobuyuki
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
N
Nakajima, Miki
- You have accessIndiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human LiverMai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
Nakamichi, Noritaka
- You have accessInteraction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in HumansKazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio KatoDrug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
Nepal, Sahadev
- You have accessWhy Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. JonesDrug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
Netterberg, Ida
- You have accessRisk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. BrouwerDrug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
Ning, Miaoran
- You have access17β-Estradiol Induces Sulfotransferase 2A1 Expression through Estrogen Receptor αWei Li, Miaoran Ning, Kwi Hye Koh, Heesue Kim and Hyunyoung JeongDrug Metabolism and Disposition April 2014, 42 (4) 796-802; DOI: https://doi.org/10.1124/dmd.113.055178
Nyagode, Beatrice A.
- You have accessSelective and Cytokine-Dependent Regulation of Hepatic Transporters and Bile Acid Homeostasis during Infectious Colitis in MiceMatthew D. Merrell, Beatrice A. Nyagode, John D. Clarke, Nathan J. Cherrington and Edward T. MorganDrug Metabolism and Disposition April 2014, 42 (4) 596-602; DOI: https://doi.org/10.1124/dmd.113.055525
O
Okudaira, Noriko
- You have accessEdoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s DispositionTsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
Ott, Gudrun
- You have accessFunctional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy CaucasiansGudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje HavemeyerDrug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
Özvegy-Laczka, Csilla
- You have accessRegulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding SitesÁgnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-LaczkaDrug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731
P
Paine, Mary F.
- You have accessUnderstanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug DevelopmentMaciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra GaletinDrug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558
Pan, Peichen
- You have accessPathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction PotentialsYedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian ZhangDrug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
Pang, Xiaoyan
- You have accessBioactivation of 3-n-Butylphthalide via Sulfation of Its Major Metabolite 3-Hydroxy-NBP: Mediated Mainly by Sulfotransferase 1A1Xingxing Diao, Xiaoyan Pang, Cen Xie, Zitao Guo, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition April 2014, 42 (4) 774-781; DOI: https://doi.org/10.1124/dmd.113.056218
Pastor, Catherine M.
- You have accessThe Role of Organic Anion Transporters in Diagnosing Liver Diseases by Magnetic Resonance ImagingCatherine M. Pastor, Beat Müllhaupt and Bruno StiegerDrug Metabolism and Disposition April 2014, 42 (4) 675-684; DOI: https://doi.org/10.1124/dmd.113.055707
Pellequer, Yann
- You have accessCoadministration of P-Glycoprotein Modulators on Loperamide Pharmacokinetics and Brain DistributionRita Nieto Montesinos, Brice Moulari, Jessica Gromand, Arnaud Beduneau, Alf Lamprecht and Yann PellequerDrug Metabolism and Disposition April 2014, 42 (4) 700-706; DOI: https://doi.org/10.1124/dmd.113.055566
Piquette-Miller, Micheline
- You have accessMalaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant MiceAlex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-MillerDrug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983
Polli, Joseph W.
- You have accessUnderstanding the Transport Properties of Metabolites: Case Studies and Considerations for Drug DevelopmentMaciej J. Zamek-Gliszczynski, Xiaoyan Chu, Joseph W. Polli, Mary F. Paine and Aleksandra GaletinDrug Metabolism and Disposition April 2014, 42 (4) 650-664; DOI: https://doi.org/10.1124/dmd.113.055558
Prakash, Chandra
- You have accessThe Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in HumansMartin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra PrakashDrug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
Pu, Jianbin
- You have accessHepatic Glucuronidation of Isoneochamaejasmin A from the Traditional Chinese Medicine Stellera Chamaejasme L. RootLushan Yu, Jianbin Pu, Minjuan Zuo, Xia Zhang, Yang Cao, Shifeng Chen, Yan Lou, Quan Zhou, Haihong Hu, Huidi Jiang, Jianzhong Chen and Su ZengDrug Metabolism and Disposition April 2014, 42 (4) 735-743; DOI: https://doi.org/10.1124/dmd.113.055962
Q
Qi, Huixin
- You have accessPathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction PotentialsYedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian ZhangDrug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
R
Reichmann, Debora
- You have accessFunctional Characterization of Protein Variants Encoded by Nonsynonymous Single Nucleotide Polymorphisms in MARC1 and MARC2 in Healthy CaucasiansGudrun Ott, Debora Reichmann, Cornelia Boerger, Ingolf Cascorbi, Florian Bittner, Ralf-Rainer Mendel, Thomas Kunze, Bernd Clement and Antje HavemeyerDrug Metabolism and Disposition April 2014, 42 (4) 718-725; DOI: https://doi.org/10.1124/dmd.113.055202
Rodrigues, A. David
- You have accessDrug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export PumpA. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. SoarsDrug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
Rostami-Hodjegan, Amin
- You have accessSimultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted ProteomicsBrahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-HodjeganDrug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632
Rozehnal, Veronika
- You have accessEdoxaban Transport via P-Glycoprotein Is a Key Factor for the Drug’s DispositionTsuyoshi Mikkaichi, Yasushi Yoshigae, Hiroshi Masumoto, Tomoki Imaoka, Veronika Rozehnal, Thomas Fischer, Noriko Okudaira and Takashi IzumiDrug Metabolism and Disposition April 2014, 42 (4) 520-528; DOI: https://doi.org/10.1124/dmd.113.054866
Russell, Matthew R.
- You have accessSimultaneous Quantification of the Abundance of Several Cytochrome P450 and Uridine 5′-Diphospho-Glucuronosyltransferase Enzymes in Human Liver Microsomes Using Multiplexed Targeted ProteomicsBrahim Achour, Matthew R. Russell, Jill Barber and Amin Rostami-HodjeganDrug Metabolism and Disposition April 2014, 42 (4) 500-510; DOI: https://doi.org/10.1124/dmd.113.055632
Ryder, Tim F.
- You have accessThe Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in HumansMartin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra PrakashDrug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
S
Sane, Ramola
- You have accessThe Effect of ABCG2 and ABCC4 on the Pharmacokinetics of Methotrexate in the BrainRamola Sane, Shu-Pei Wu, Rong Zhang and James M. GalloDrug Metabolism and Disposition April 2014, 42 (4) 537-540; DOI: https://doi.org/10.1124/dmd.113.055228
Sarkadi, Balázs
- You have accessRegulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding SitesÁgnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-LaczkaDrug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731
Sato, Ren
- You have accessInteraction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in HumansKazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio KatoDrug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
Schuetz, Erin G.
- You have accessWhy Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. JonesDrug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
Schuetz, John D.
- You have accessThe Role of Transporters in Toxicity and DiseaseJohn D. Schuetz, Peter W. Swaan and Donald J. TweedieDrug Metabolism and Disposition April 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539
Shimizu, Mai
- You have accessIndiplon Is Hydrolyzed by Arylacetamide Deacetylase in Human LiverMai Shimizu, Tatsuki Fukami, Yusuke Ito, Takaya Kurokawa, Motoki Kariya, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition April 2014, 42 (4) 751-758; DOI: https://doi.org/10.1124/dmd.113.056184
Shimizu, Takuya
- You have accessInteraction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in HumansKazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio KatoDrug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
Silver, Karlee
- You have accessMalaria Infection Alters the Expression of Hepatobiliary and Placental Drug Transporters in Pregnant MiceAlex M. Cressman, Chloe R. McDonald, Karlee Silver, Kevin C. Kain and Micheline Piquette-MillerDrug Metabolism and Disposition April 2014, 42 (4) 603-610; DOI: https://doi.org/10.1124/dmd.113.053983
Soars, Matthew G.
- You have accessDrug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export PumpA. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. SoarsDrug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
Sparreboom, Alex
- You have accessUptake Carriers and Oncology Drug SafetyJason A. Sprowl and Alex SparreboomDrug Metabolism and Disposition April 2014, 42 (4) 611-622; DOI: https://doi.org/10.1124/dmd.113.055806
Sprowl, Jason A.
- You have accessUptake Carriers and Oncology Drug SafetyJason A. Sprowl and Alex SparreboomDrug Metabolism and Disposition April 2014, 42 (4) 611-622; DOI: https://doi.org/10.1124/dmd.113.055806
Stewart, Paul W.
- You have accessRisk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. BrouwerDrug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
Stieger, Bruno
- You have accessThe Role of Organic Anion Transporters in Diagnosing Liver Diseases by Magnetic Resonance ImagingCatherine M. Pastor, Beat Müllhaupt and Bruno StiegerDrug Metabolism and Disposition April 2014, 42 (4) 675-684; DOI: https://doi.org/10.1124/dmd.113.055707
Strom, Stephen C.
- You have accessWhy Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. JonesDrug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
Sugiura, Tomoko
- You have accessInteraction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in HumansKazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio KatoDrug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
Sugiyama, Yuichi
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
Swaan, Peter W.
- You have accessThe Role of Transporters in Toxicity and DiseaseJohn D. Schuetz, Peter W. Swaan and Donald J. TweedieDrug Metabolism and Disposition April 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539
- You have accessRisk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. BrouwerDrug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
T
Tajima, Kazuo
- You have accessCloning and Characterization of Four Rabbit Aldo-Keto Reductases Featuring Broad Substrate Specificity for Xenobiotic and Endogenous Carbonyl Compounds: Relationship with Multiple Forms of Drug Ketone ReductasesSatoshi Endo, Toshiyuki Matsunaga, Yuki Arai, Akira Ikari, Kazuo Tajima, Ossama El-Kabbani, Shigeru Yamano, Akira Hara and Yukio KitadeDrug Metabolism and Disposition April 2014, 42 (4) 803-812; DOI: https://doi.org/10.1124/dmd.113.056044
Takeuchi, Kazuya
- You have accessInteraction of Novel Platelet-Increasing Agent Eltrombopag with Rosuvastatin via Breast Cancer Resistance Protein in HumansKazuya Takeuchi, Tomoko Sugiura, Kazuki Matsubara, Ren Sato, Takuya Shimizu, Yusuke Masuo, Masato Horikawa, Noritaka Nakamichi, Norihisa Ishiwata and Yukio KatoDrug Metabolism and Disposition April 2014, 42 (4) 726-734; DOI: https://doi.org/10.1124/dmd.113.054767
Tang, Xianqing
- You have accessN-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun DengDrug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
Teffera, Yohannes
- You have accessSpecies Difference in Glucuronidation Formation Kinetics with a Selective mTOR InhibitorLoren M. Berry, Jingzhou Liu, Adria Colletti, Paul Krolikowski, Zhiyang Zhao and Yohannes TefferaDrug Metabolism and Disposition April 2014, 42 (4) 707-717; DOI: https://doi.org/10.1124/dmd.113.054809
Telbisz, Ágnes
- You have accessRegulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding SitesÁgnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-LaczkaDrug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731
Thummel, Kenneth E.
- You have accessWhy Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. JonesDrug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
Tong, Weida
- You have accessHigh Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver InjuryKe Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida TongDrug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
Trauner, Michael
- You have accessThe Role of Canalicular ABC Transporters in CholestasisFrans J. C. Cuperus, Thierry Claudel, Julien Gautherot, Emina Halilbasic and Michael TraunerDrug Metabolism and Disposition April 2014, 42 (4) 546-560; DOI: https://doi.org/10.1124/dmd.113.056358
Tsuruya, Yuri
- You have access6β-Hydroxycortisol Is an Endogenous Probe for Evaluation of Drug–Drug Interactions Involving a Multispecific Renal Organic Anion Transporter, OAT3/SLC22A8, in Healthy SubjectsYuichiro Imamura, Yuri Tsuruya, Katja Damme, Dominik Heer, Yuji Kumagai, Kazuya Maeda, Nobuyuki Murayama, Noriko Okudaira, Atsushi Kurihara, Takashi Izumi, Yuichi Sugiyama and Hiroyuki KusuharaDrug Metabolism and Disposition April 2014, 42 (4) 685-694; DOI: https://doi.org/10.1124/dmd.113.055475
Tweedie, Donald J.
- You have accessThe Role of Transporters in Toxicity and DiseaseJohn D. Schuetz, Peter W. Swaan and Donald J. TweedieDrug Metabolism and Disposition April 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539
U
Urban, Thomas J.
- You have accessRisk Factors for Development of Cholestatic Drug-Induced Liver Injury: Inhibition of Hepatic Basolateral Bile Acid Transporters Multidrug Resistance-Associated Proteins 3 and 4Kathleen Köck, Brian C. Ferslew, Ida Netterberg, Kyunghee Yang, Thomas J. Urban, Peter W. Swaan, Paul W. Stewart and Kim L. R. BrouwerDrug Metabolism and Disposition April 2014, 42 (4) 665-674; DOI: https://doi.org/10.1124/dmd.113.054304
V
Váradi, András
- You have accessRegulation of the Function of the Human ABCG2 Multidrug Transporter by Cholesterol and Bile Acids: Effects of Mutations in Potential Substrate and Steroid Binding SitesÁgnes Telbisz, Csilla Hegedüs, András Váradi, Balázs Sarkadi and Csilla Özvegy-LaczkaDrug Metabolism and Disposition April 2014, 42 (4) 575-585; DOI: https://doi.org/10.1124/dmd.113.055731
Vaz, Alfin
- You have accessThe Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in HumansMartin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra PrakashDrug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
W
Walker, Gregory S.
- You have accessThe Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in HumansMartin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra PrakashDrug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
Wang, Bingshun
- You have accessHigh Daily Dose and Being a Substrate of Cytochrome P450 Enzymes Are Two Important Predictors of Drug-Induced Liver InjuryKe Yu, Xingchao Geng, Minjun Chen, Jie Zhang, Bingshun Wang, Katarina Ilic and Weida TongDrug Metabolism and Disposition April 2014, 42 (4) 744-750; DOI: https://doi.org/10.1124/dmd.113.056267
Wang, Lijuan
- You have accessN-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun DengDrug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
Wang, Meiyu
- You have accessPathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction PotentialsYedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian ZhangDrug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
Wang, Weiwei
- You have accessThe Pharmacokinetics, Metabolism, and Clearance Mechanisms of Tofacitinib, a Janus Kinase Inhibitor, in HumansMartin E. Dowty, Jinyan Lin, Tim F. Ryder, Weiwei Wang, Gregory S. Walker, Alfin Vaz, Gary L. Chan, Sriram Krishnaswami and Chandra PrakashDrug Metabolism and Disposition April 2014, 42 (4) 759-773; DOI: https://doi.org/10.1124/dmd.113.054940
Wang, Yedong
- You have accessPathway-Dependent Inhibition of Paclitaxel Hydroxylation by Kinase Inhibitors and Assessment of Drug–Drug Interaction PotentialsYedong Wang, Meiyu Wang, Huixin Qi, Peichen Pan, Tingjun Hou, Jiajun Li, Guangzhao He and Hongjian ZhangDrug Metabolism and Disposition April 2014, 42 (4) 782-795; DOI: https://doi.org/10.1124/dmd.113.053793
Wang, Yufan
- You have accessN-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun DengDrug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
Wilson, Mike R.
- You have accessThe Major Facilitative Folate Transporters Solute Carrier 19A1 and Solute Carrier 46A1: Biology and Role in Antifolate Chemotherapy of CancerLarry H. Matherly, Mike R. Wilson and Zhanjun HouDrug Metabolism and Disposition April 2014, 42 (4) 632-649; DOI: https://doi.org/10.1124/dmd.113.055723
Wong, Timothy
- You have accessWhy Do Most Human Liver Cytosol Preparations Lack Xanthine Oxidase Activity?John T. Barr, Kanika V. Choughule, Sahadev Nepal, Timothy Wong, Amarjit S. Chaudhry, Carolyn A. Joswig-Jones, Michael Zientek, Stephen C. Strom, Erin G. Schuetz, Kenneth E. Thummel and Jeffrey P. JonesDrug Metabolism and Disposition April 2014, 42 (4) 695-699; DOI: https://doi.org/10.1124/dmd.113.056374
Wu, Kaixin
- You have accessN-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun DengDrug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
Wu, Shu-Pei
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Xu, Ming
- You have accessN-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun DengDrug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
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Yamano, Shigeru
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Zamek-Gliszczynski, Maciej J.
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Zeng, Su
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Zhang, Hongjian
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Zheng, Yuanming
- You have accessN-Oxide Reduction of Quinoxaline-1,4-Dioxides Catalyzed by Porcine Aldehyde Oxidase SsAOX1Peiqiang Mu, Ming Zheng, Ming Xu, Yuanming Zheng, Xianqing Tang, Yufan Wang, Kaixin Wu, Qingmei Chen, Lijuan Wang and Yiqun DengDrug Metabolism and Disposition April 2014, 42 (4) 511-519; DOI: https://doi.org/10.1124/dmd.113.055418
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Zientek, Michael
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Zvyaga, Tatyana
- You have accessDrug-Induced Perturbations of the Bile Acid Pool, Cholestasis, and Hepatotoxicity: Mechanistic Considerations beyond the Direct Inhibition of the Bile Salt Export PumpA. David Rodrigues, Yurong Lai, Mary Ellen Cvijic, Lisa L. Elkin, Tatyana Zvyaga and Matthew G. SoarsDrug Metabolism and Disposition April 2014, 42 (4) 566-574; DOI: https://doi.org/10.1124/dmd.113.054205
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