Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats

Xingrong Liu; Jonathan Cheong; Xiao Ding; Gauri Deshmukh

doi:10.1124/dmd.113.055590

Research ArticleArticle

Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats

Xingrong Liu, Jonathan Cheong, Xiao Ding and Gauri Deshmukh

Drug Metabolism and Disposition April 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590

Xingrong Liu

Genentech, Inc., South San Francisco, California

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Jonathan Cheong

Genentech, Inc., South San Francisco, California

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Xiao Ding

Genentech, Inc., South San Francisco, California

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Gauri Deshmukh

Genentech, Inc., South San Francisco, California

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Drug Metabolism and Disposition

Vol. 42, Issue 4

1 Apr 2014

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Research ArticleArticle

Brain Penetration in Wild-Type and P-gp Knockout Rats

Xingrong Liu, Jonathan Cheong, Xiao Ding and Gauri Deshmukh

Drug Metabolism and Disposition April 1, 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590

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Research ArticleArticle

Brain Penetration in Wild-Type and P-gp Knockout Rats

Xingrong Liu, Jonathan Cheong, Xiao Ding and Gauri Deshmukh

Drug Metabolism and Disposition April 1, 2014, 42 (4) 482-491; DOI: https://doi.org/10.1124/dmd.113.055590

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Use of Cassette Dosing Approach to Examine the Effects of P-Glycoprotein on the Brain and Cerebrospinal Fluid Concentrations in Wild-Type and P-Glycoprotein Knockout Rats

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