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Research ArticleSpecial Section on Transporters in Toxicity and Disease

The Role of Transporters in Toxicity and Disease

John D. Schuetz, Peter W. Swaan and Donald J. Tweedie
Drug Metabolism and Disposition April 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539
John D. Schuetz
Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (J.D.S); Department of Pharmaceutical Sciences, University of Maryland, Baltimore, Maryland (P.W.S); and Department of Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim, Ridgefield, Connecticut (D.J.T.)
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Peter W. Swaan
Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (J.D.S); Department of Pharmaceutical Sciences, University of Maryland, Baltimore, Maryland (P.W.S); and Department of Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim, Ridgefield, Connecticut (D.J.T.)
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Donald J. Tweedie
Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (J.D.S); Department of Pharmaceutical Sciences, University of Maryland, Baltimore, Maryland (P.W.S); and Department of Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim, Ridgefield, Connecticut (D.J.T.)
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Article Information

vol. 42 no. 4 541-545
DOI 
https://doi.org/10.1124/dmd.114.057539
PubMed 
24598705

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received February 5, 2014
  • Accepted February 7, 2014
  • Published online March 5, 2014.

Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. John D. Schuetz,
  2. Peter W. Swaan, and
  3. Donald J. Tweedie
  1. Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, Memphis, Tennessee (J.D.S); Department of Pharmaceutical Sciences, University of Maryland, Baltimore, Maryland (P.W.S); and Department of Drug Metabolism and Pharmacokinetics, Boehringer Ingelheim, Ridgefield, Connecticut (D.J.T.)
  1. Address correspondence to:
    Dr. John D. Schuetz, Department of Pharmaceutical Sciences, St. Jude Children’s Research Hospital, 262 Danny Thomas Place, MS 313, Memphis, Tennessee 38105. E-mail: john.schuetz{at}stjude.org
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Drug Metabolism and Disposition: 42 (4)
Drug Metabolism and Disposition
Vol. 42, Issue 4
1 Apr 2014
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Research ArticleSpecial Section on Transporters in Toxicity and Disease

Transporters in Toxicity and Disease

John D. Schuetz, Peter W. Swaan and Donald J. Tweedie
Drug Metabolism and Disposition April 1, 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539

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Research ArticleSpecial Section on Transporters in Toxicity and Disease

Transporters in Toxicity and Disease

John D. Schuetz, Peter W. Swaan and Donald J. Tweedie
Drug Metabolism and Disposition April 1, 2014, 42 (4) 541-545; DOI: https://doi.org/10.1124/dmd.114.057539
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  • Article
    • Abstract
    • Introduction
    • Liver Transporters in Health and Disease
    • Transporters and Oncology
    • Transporters and Drug Interactions
    • In Vivo Probes to Dissect Transporter Interaction
    • Conclusions
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
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