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Rapid CommunicationSpecial Section on Transporters in Toxicity and Disease

The Roles of MRP2, MRP3, OATP1B1, and OATP1B3 in Conjugated Hyperbilirubinemia

Dietrich Keppler
Drug Metabolism and Disposition April 2014, 42 (4) 561-565; DOI: https://doi.org/10.1124/dmd.113.055772
Dietrich Keppler
German Cancer Research Center (DKFZ), Heidelberg, Germany
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Article Information

vol. 42 no. 4 561-565
DOI 
https://doi.org/10.1124/dmd.113.055772
PubMed 
24459177

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received November 3, 2013
  • Accepted January 23, 2014
  • Published online March 6, 2014.

Article Versions

  • Earlier version (January 23, 2014 - 07:24).
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Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Dietrich Keppler
  1. German Cancer Research Center (DKFZ), Heidelberg, Germany
  1. Address correspondence to:
    Dr. Dietrich Keppler, German Cancer Research Center, Im Neuenheimer Feld 280, D-69120 Heidelberg, Germany. E-mail: d.keppler{at}dkfz.de
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Drug Metabolism and Disposition: 42 (4)
Drug Metabolism and Disposition
Vol. 42, Issue 4
1 Apr 2014
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Rapid CommunicationSpecial Section on Transporters in Toxicity and Disease

MRP2, MRP3, and OATPs in Conjugated Hyperbilirubinemia

Dietrich Keppler
Drug Metabolism and Disposition April 1, 2014, 42 (4) 561-565; DOI: https://doi.org/10.1124/dmd.113.055772

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Rapid CommunicationSpecial Section on Transporters in Toxicity and Disease

MRP2, MRP3, and OATPs in Conjugated Hyperbilirubinemia

Dietrich Keppler
Drug Metabolism and Disposition April 1, 2014, 42 (4) 561-565; DOI: https://doi.org/10.1124/dmd.113.055772
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  • Article
    • Abstract
    • MRP2 and MRP3 Are Conjugate and Drug Efflux Pumps of the Multidrug Resistance Protein (ATP-Binding Cassette Protein, Subfamily C) Subfamily of ATP-Dependent Transport Proteins
    • Transport of Unconjugated Bilirubin into Human Hepatocytes
    • Transport of Conjugated Bilirubin by Human Hepatocytes
    • Predominantly Conjugated Hyperbilirubinemia in Rotor Syndrome
    • Predominantly Conjugated Hyperbilirubinemia in Dubin-Johnson Syndrome
    • Authorship Contributions
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    • Abbreviations
    • References
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