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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
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Index by author

June 01, 2014; Volume 42,Issue 6
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

B

  1. Bateman, Thomas J.

    1. You have access
      Application of Chimeric Mice with Humanized Liver for Study of Human-Specific Drug Metabolism
      Thomas J. Bateman, Vijay G.B. Reddy, Masakazu Kakuni, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition June 2014, 42 (6) 1055-1065; DOI: https://doi.org/10.1124/dmd.114.056978
  2. Boxberger, Kelli H.

    1. You have access
      Common Drugs Inhibit Human Organic Cation Transporter 1 (OCT1)-Mediated Neurotransmitter Uptake
      Kelli H. Boxberger, Bruno Hagenbuch and Jed N. Lampe
      Drug Metabolism and Disposition June 2014, 42 (6) 990-995; DOI: https://doi.org/10.1124/dmd.113.055095
  3. Brown, Caitlin

    1. You have access
      Aldehyde Oxidase Activity in Donor-Matched Fresh and Cryopreserved Human Hepatocytes and Assessment of Variability in 75 Donors
      J. Matthew Hutzler, Young-Sun Yang, Caitlin Brown, Scott Heyward and Timothy Moeller
      Drug Metabolism and Disposition June 2014, 42 (6) 1090-1097; DOI: https://doi.org/10.1124/dmd.114.057984
  4. Bulitta, Jurgen B.

    1. You have access
      Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor
      Beom Soo Shin, Sun Dong Yoo, Tae Hwan Kim, Jurgen B. Bulitta, Cornelia B. Landersdorfer, Jeong Cheol Shin, Jin Ho Choi, Kwon-Yeon Weon, Sang Hoon Joo and Soyoung Shin
      Drug Metabolism and Disposition June 2014, 42 (6) 974-982; DOI: https://doi.org/10.1124/dmd.113.056713

C

  1. Cai, Ping

    1. You have access
      Paradoxical Attenuation of Autoimmune Hepatitis by Oral Isoniazid in Wild-Type and N-Acetyltransferase–Deficient Mice
      Imir G. Metushi, Ping Cai, Libia Vega, Denis M. Grant and Jack Uetrecht
      Drug Metabolism and Disposition June 2014, 42 (6) 963-973; DOI: https://doi.org/10.1124/dmd.113.056622
  2. Cang, Jian

    1. You have access
      Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat
      Chong Wang, Changyuan Wang, Qi Liu, Qiang Meng, Jian Cang, Huijun Sun, Jinyong Peng, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition June 2014, 42 (6) 996-1007; DOI: https://doi.org/10.1124/dmd.113.055194
  3. Chang, Jae H.

    1. You have access
      Differential Effects of Rifampin and Ketoconazole on the Blood and Liver Concentration of Atorvastatin in Wild-Type and Cyp3a and Oatp1a/b Knockout Mice
      Jae H. Chang, Justin Ly, Emile Plise, Xiaolin Zhang, Kirsten Messick, Matthew Wright and Jonathan Cheong
      Drug Metabolism and Disposition June 2014, 42 (6) 1067-1073; DOI: https://doi.org/10.1124/dmd.114.057968
  4. Cheong, Jonathan

    1. You have access
      Differential Effects of Rifampin and Ketoconazole on the Blood and Liver Concentration of Atorvastatin in Wild-Type and Cyp3a and Oatp1a/b Knockout Mice
      Jae H. Chang, Justin Ly, Emile Plise, Xiaolin Zhang, Kirsten Messick, Matthew Wright and Jonathan Cheong
      Drug Metabolism and Disposition June 2014, 42 (6) 1067-1073; DOI: https://doi.org/10.1124/dmd.114.057968
  5. Choi, Jin Ho

    1. You have access
      Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor
      Beom Soo Shin, Sun Dong Yoo, Tae Hwan Kim, Jurgen B. Bulitta, Cornelia B. Landersdorfer, Jeong Cheol Shin, Jin Ho Choi, Kwon-Yeon Weon, Sang Hoon Joo and Soyoung Shin
      Drug Metabolism and Disposition June 2014, 42 (6) 974-982; DOI: https://doi.org/10.1124/dmd.113.056713
  6. Cyphert, Jaime M.

    1. You have access
      Mice Lacking Three Loci Encoding 14 Glutathione Transferase Genes: A Novel Tool for Assigning Function to the GSTP, GSTM, and GSTT Families
      Zhidan Xiang, John N. Snouwaert, Martina Kovarova, MyTrang Nguyen, Peter W. Repenning, Anne M. Latour, Jaime M. Cyphert and Beverly H. Koller
      Drug Metabolism and Disposition June 2014, 42 (6) 1074-1083; DOI: https://doi.org/10.1124/dmd.113.056481

E

  1. Ekdahl, Anja

    1. You have access
      Systemic Exposure to the Metabolites of Lesogaberan in Humans and Animals: A Case Study of Metabolites in Safety Testing
      Ann Aurell Holmberg, Anja Ekdahl and Lars Weidolf
      Drug Metabolism and Disposition June 2014, 42 (6) 1016-1021; DOI: https://doi.org/10.1124/dmd.113.056614

F

  1. Fuse, Eiichi

    1. You have access
      Quantitative Investigation of the Brain-to-Cerebrospinal Fluid Unbound Drug Concentration Ratio under Steady-State Conditions in Rats Using a Pharmacokinetic Model and Scaling Factors for Active Efflux Transporters
      Hiroshi Kodaira, Hiroyuki Kusuhara, Eiichi Fuse, Junko Ushiki and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2014, 42 (6) 983-989; DOI: https://doi.org/10.1124/dmd.113.056606

G

  1. Grant, Denis M.

    1. You have access
      Paradoxical Attenuation of Autoimmune Hepatitis by Oral Isoniazid in Wild-Type and N-Acetyltransferase–Deficient Mice
      Imir G. Metushi, Ping Cai, Libia Vega, Denis M. Grant and Jack Uetrecht
      Drug Metabolism and Disposition June 2014, 42 (6) 963-973; DOI: https://doi.org/10.1124/dmd.113.056622

H

  1. Hagenbuch, Bruno

    1. You have access
      Common Drugs Inhibit Human Organic Cation Transporter 1 (OCT1)-Mediated Neurotransmitter Uptake
      Kelli H. Boxberger, Bruno Hagenbuch and Jed N. Lampe
      Drug Metabolism and Disposition June 2014, 42 (6) 990-995; DOI: https://doi.org/10.1124/dmd.113.055095
  2. Henderson, Colin J.

    1. You have access
      Deletion of 30 Murine Cytochrome P450 Genes Results In Viable Mice With Compromised Drug Metabolism
      Nico Scheer, Lesley A. McLaughlin, Anja Rode, A. Kenneth MacLeod, Colin J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition June 2014, 42 (6) 1022-1030; DOI: https://doi.org/10.1124/dmd.114.057885
  3. Heyward, Scott

    1. You have access
      Aldehyde Oxidase Activity in Donor-Matched Fresh and Cryopreserved Human Hepatocytes and Assessment of Variability in 75 Donors
      J. Matthew Hutzler, Young-Sun Yang, Caitlin Brown, Scott Heyward and Timothy Moeller
      Drug Metabolism and Disposition June 2014, 42 (6) 1090-1097; DOI: https://doi.org/10.1124/dmd.114.057984
  4. Holmberg, Ann Aurell

    1. You have access
      Systemic Exposure to the Metabolites of Lesogaberan in Humans and Animals: A Case Study of Metabolites in Safety Testing
      Ann Aurell Holmberg, Anja Ekdahl and Lars Weidolf
      Drug Metabolism and Disposition June 2014, 42 (6) 1016-1021; DOI: https://doi.org/10.1124/dmd.113.056614
  5. Horie, Toru

    1. You have access
      Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
      Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie and Tetsuya Terasaki
      Drug Metabolism and Disposition June 2014, 42 (6) 1039-1043; DOI: https://doi.org/10.1124/dmd.114.057646
  6. Huo, Xiaokui

    1. You have access
      Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat
      Chong Wang, Changyuan Wang, Qi Liu, Qiang Meng, Jian Cang, Huijun Sun, Jinyong Peng, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition June 2014, 42 (6) 996-1007; DOI: https://doi.org/10.1124/dmd.113.055194
  7. Hutzler, J. Matthew

    1. You have access
      Aldehyde Oxidase Activity in Donor-Matched Fresh and Cryopreserved Human Hepatocytes and Assessment of Variability in 75 Donors
      J. Matthew Hutzler, Young-Sun Yang, Caitlin Brown, Scott Heyward and Timothy Moeller
      Drug Metabolism and Disposition June 2014, 42 (6) 1090-1097; DOI: https://doi.org/10.1124/dmd.114.057984

I

  1. Inoue, Tae

    1. You have access
      Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
      Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie and Tetsuya Terasaki
      Drug Metabolism and Disposition June 2014, 42 (6) 1039-1043; DOI: https://doi.org/10.1124/dmd.114.057646
  2. Inouye, Yoshio

    1. You have access
      Nigramide C Is a Natural Agonist of Human Pregnane X Receptor
      Yuichiro Kanno, Tomofumi Yatsu, Wei Li, Kazuo Koike and Yoshio Inouye
      Drug Metabolism and Disposition June 2014, 42 (6) 1084-1089; DOI: https://doi.org/10.1124/dmd.114.057810
  3. Izumi, Takashi

    1. You have access
      Identification of Bioactivating Enzymes Involved in the Hydrolysis of Laninamivir Octanoate, a Long-Acting Neuraminidase Inhibitor, in Human Pulmonary Tissue
      Kumiko Koyama, Yuji Ogura, Daisuke Nakai, Mihoko Watanabe, Toshiko Munemasa, Yuka Oofune, Kazuishi Kubota, Akira Shinagawa and Takashi Izumi
      Drug Metabolism and Disposition June 2014, 42 (6) 1031-1038; DOI: https://doi.org/10.1124/dmd.114.057620

J

  1. Joo, Sang Hoon

    1. You have access
      Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor
      Beom Soo Shin, Sun Dong Yoo, Tae Hwan Kim, Jurgen B. Bulitta, Cornelia B. Landersdorfer, Jeong Cheol Shin, Jin Ho Choi, Kwon-Yeon Weon, Sang Hoon Joo and Soyoung Shin
      Drug Metabolism and Disposition June 2014, 42 (6) 974-982; DOI: https://doi.org/10.1124/dmd.113.056713

K

  1. Kakuni, Masakazu

    1. You have access
      Application of Chimeric Mice with Humanized Liver for Study of Human-Specific Drug Metabolism
      Thomas J. Bateman, Vijay G.B. Reddy, Masakazu Kakuni, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition June 2014, 42 (6) 1055-1065; DOI: https://doi.org/10.1124/dmd.114.056978
  2. Kamiie, Junichi

    1. You have access
      Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
      Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie and Tetsuya Terasaki
      Drug Metabolism and Disposition June 2014, 42 (6) 1039-1043; DOI: https://doi.org/10.1124/dmd.114.057646
  3. Kanno, Yuichiro

    1. You have access
      Nigramide C Is a Natural Agonist of Human Pregnane X Receptor
      Yuichiro Kanno, Tomofumi Yatsu, Wei Li, Kazuo Koike and Yoshio Inouye
      Drug Metabolism and Disposition June 2014, 42 (6) 1084-1089; DOI: https://doi.org/10.1124/dmd.114.057810
  4. Katsukura, Yuki

    1. You have access
      Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
      Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie and Tetsuya Terasaki
      Drug Metabolism and Disposition June 2014, 42 (6) 1039-1043; DOI: https://doi.org/10.1124/dmd.114.057646
  5. Kawakami, Hirotaka

    1. You have access
      Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
      Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie and Tetsuya Terasaki
      Drug Metabolism and Disposition June 2014, 42 (6) 1039-1043; DOI: https://doi.org/10.1124/dmd.114.057646
  6. Ke, Alice B.

    1. You have access
      Investigational Small-Molecule Drug Selectively Suppresses Constitutive CYP2B6 Activity at the Gene Transcription Level: Physiologically Based Pharmacokinetic Model Assessment of Clinical Drug Interaction Risk
      Maciej J. Zamek-Gliszczynski, Michael A. Mohutsky, Jessica L. F. Rehmel and Alice B. Ke
      Drug Metabolism and Disposition June 2014, 42 (6) 1008-1015; DOI: https://doi.org/10.1124/dmd.114.057018
  7. Kim, Tae Hwan

    1. You have access
      Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor
      Beom Soo Shin, Sun Dong Yoo, Tae Hwan Kim, Jurgen B. Bulitta, Cornelia B. Landersdorfer, Jeong Cheol Shin, Jin Ho Choi, Kwon-Yeon Weon, Sang Hoon Joo and Soyoung Shin
      Drug Metabolism and Disposition June 2014, 42 (6) 974-982; DOI: https://doi.org/10.1124/dmd.113.056713
  8. Kodaira, Hiroshi

    1. You have access
      Quantitative Investigation of the Brain-to-Cerebrospinal Fluid Unbound Drug Concentration Ratio under Steady-State Conditions in Rats Using a Pharmacokinetic Model and Scaling Factors for Active Efflux Transporters
      Hiroshi Kodaira, Hiroyuki Kusuhara, Eiichi Fuse, Junko Ushiki and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2014, 42 (6) 983-989; DOI: https://doi.org/10.1124/dmd.113.056606
  9. Koike, Kazuo

    1. You have access
      Nigramide C Is a Natural Agonist of Human Pregnane X Receptor
      Yuichiro Kanno, Tomofumi Yatsu, Wei Li, Kazuo Koike and Yoshio Inouye
      Drug Metabolism and Disposition June 2014, 42 (6) 1084-1089; DOI: https://doi.org/10.1124/dmd.114.057810
  10. Koller, Beverly H.

    1. You have access
      Mice Lacking Three Loci Encoding 14 Glutathione Transferase Genes: A Novel Tool for Assigning Function to the GSTP, GSTM, and GSTT Families
      Zhidan Xiang, John N. Snouwaert, Martina Kovarova, MyTrang Nguyen, Peter W. Repenning, Anne M. Latour, Jaime M. Cyphert and Beverly H. Koller
      Drug Metabolism and Disposition June 2014, 42 (6) 1074-1083; DOI: https://doi.org/10.1124/dmd.113.056481
  11. Kovarova, Martina

    1. You have access
      Mice Lacking Three Loci Encoding 14 Glutathione Transferase Genes: A Novel Tool for Assigning Function to the GSTP, GSTM, and GSTT Families
      Zhidan Xiang, John N. Snouwaert, Martina Kovarova, MyTrang Nguyen, Peter W. Repenning, Anne M. Latour, Jaime M. Cyphert and Beverly H. Koller
      Drug Metabolism and Disposition June 2014, 42 (6) 1074-1083; DOI: https://doi.org/10.1124/dmd.113.056481
  12. Koyama, Kumiko

    1. You have access
      Identification of Bioactivating Enzymes Involved in the Hydrolysis of Laninamivir Octanoate, a Long-Acting Neuraminidase Inhibitor, in Human Pulmonary Tissue
      Kumiko Koyama, Yuji Ogura, Daisuke Nakai, Mihoko Watanabe, Toshiko Munemasa, Yuka Oofune, Kazuishi Kubota, Akira Shinagawa and Takashi Izumi
      Drug Metabolism and Disposition June 2014, 42 (6) 1031-1038; DOI: https://doi.org/10.1124/dmd.114.057620
  13. Kubota, Kazuishi

    1. You have access
      Identification of Bioactivating Enzymes Involved in the Hydrolysis of Laninamivir Octanoate, a Long-Acting Neuraminidase Inhibitor, in Human Pulmonary Tissue
      Kumiko Koyama, Yuji Ogura, Daisuke Nakai, Mihoko Watanabe, Toshiko Munemasa, Yuka Oofune, Kazuishi Kubota, Akira Shinagawa and Takashi Izumi
      Drug Metabolism and Disposition June 2014, 42 (6) 1031-1038; DOI: https://doi.org/10.1124/dmd.114.057620
  14. Kumar, Sanjeev

    1. You have access
      Application of Chimeric Mice with Humanized Liver for Study of Human-Specific Drug Metabolism
      Thomas J. Bateman, Vijay G.B. Reddy, Masakazu Kakuni, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition June 2014, 42 (6) 1055-1065; DOI: https://doi.org/10.1124/dmd.114.056978
  15. Kusuhara, Hiroyuki

    1. You have access
      Quantitative Investigation of the Brain-to-Cerebrospinal Fluid Unbound Drug Concentration Ratio under Steady-State Conditions in Rats Using a Pharmacokinetic Model and Scaling Factors for Active Efflux Transporters
      Hiroshi Kodaira, Hiroyuki Kusuhara, Eiichi Fuse, Junko Ushiki and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2014, 42 (6) 983-989; DOI: https://doi.org/10.1124/dmd.113.056606

L

  1. Lampe, Jed N.

    1. You have access
      Common Drugs Inhibit Human Organic Cation Transporter 1 (OCT1)-Mediated Neurotransmitter Uptake
      Kelli H. Boxberger, Bruno Hagenbuch and Jed N. Lampe
      Drug Metabolism and Disposition June 2014, 42 (6) 990-995; DOI: https://doi.org/10.1124/dmd.113.055095
  2. Landersdorfer, Cornelia B.

    1. You have access
      Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor
      Beom Soo Shin, Sun Dong Yoo, Tae Hwan Kim, Jurgen B. Bulitta, Cornelia B. Landersdorfer, Jeong Cheol Shin, Jin Ho Choi, Kwon-Yeon Weon, Sang Hoon Joo and Soyoung Shin
      Drug Metabolism and Disposition June 2014, 42 (6) 974-982; DOI: https://doi.org/10.1124/dmd.113.056713
  3. Latour, Anne M.

    1. You have access
      Mice Lacking Three Loci Encoding 14 Glutathione Transferase Genes: A Novel Tool for Assigning Function to the GSTP, GSTM, and GSTT Families
      Zhidan Xiang, John N. Snouwaert, Martina Kovarova, MyTrang Nguyen, Peter W. Repenning, Anne M. Latour, Jaime M. Cyphert and Beverly H. Koller
      Drug Metabolism and Disposition June 2014, 42 (6) 1074-1083; DOI: https://doi.org/10.1124/dmd.113.056481
  4. Li, Wei

    1. You have access
      Nigramide C Is a Natural Agonist of Human Pregnane X Receptor
      Yuichiro Kanno, Tomofumi Yatsu, Wei Li, Kazuo Koike and Yoshio Inouye
      Drug Metabolism and Disposition June 2014, 42 (6) 1084-1089; DOI: https://doi.org/10.1124/dmd.114.057810
  5. Liu, Kexin

    1. You have access
      Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat
      Chong Wang, Changyuan Wang, Qi Liu, Qiang Meng, Jian Cang, Huijun Sun, Jinyong Peng, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition June 2014, 42 (6) 996-1007; DOI: https://doi.org/10.1124/dmd.113.055194
  6. Liu, Liling

    1. You have access
      Metabolic Activation of the Indoloquinazoline Alkaloids Evodiamine and Rutaecarpine by Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4
      Bo Wen, Vikram Roongta, Liling Liu and David J. Moore
      Drug Metabolism and Disposition June 2014, 42 (6) 1044-1054; DOI: https://doi.org/10.1124/dmd.114.057414
  7. Liu, Qi

    1. You have access
      Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat
      Chong Wang, Changyuan Wang, Qi Liu, Qiang Meng, Jian Cang, Huijun Sun, Jinyong Peng, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition June 2014, 42 (6) 996-1007; DOI: https://doi.org/10.1124/dmd.113.055194
  8. Ly, Justin

    1. You have access
      Differential Effects of Rifampin and Ketoconazole on the Blood and Liver Concentration of Atorvastatin in Wild-Type and Cyp3a and Oatp1a/b Knockout Mice
      Jae H. Chang, Justin Ly, Emile Plise, Xiaolin Zhang, Kirsten Messick, Matthew Wright and Jonathan Cheong
      Drug Metabolism and Disposition June 2014, 42 (6) 1067-1073; DOI: https://doi.org/10.1124/dmd.114.057968

M

  1. Ma, Xiaochi

    1. You have access
      Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat
      Chong Wang, Changyuan Wang, Qi Liu, Qiang Meng, Jian Cang, Huijun Sun, Jinyong Peng, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition June 2014, 42 (6) 996-1007; DOI: https://doi.org/10.1124/dmd.113.055194
  2. MacLeod, A. Kenneth

    1. You have access
      Deletion of 30 Murine Cytochrome P450 Genes Results In Viable Mice With Compromised Drug Metabolism
      Nico Scheer, Lesley A. McLaughlin, Anja Rode, A. Kenneth MacLeod, Colin J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition June 2014, 42 (6) 1022-1030; DOI: https://doi.org/10.1124/dmd.114.057885
  3. McLaughlin, Lesley A.

    1. You have access
      Deletion of 30 Murine Cytochrome P450 Genes Results In Viable Mice With Compromised Drug Metabolism
      Nico Scheer, Lesley A. McLaughlin, Anja Rode, A. Kenneth MacLeod, Colin J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition June 2014, 42 (6) 1022-1030; DOI: https://doi.org/10.1124/dmd.114.057885
  4. Meng, Qiang

    1. You have access
      Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat
      Chong Wang, Changyuan Wang, Qi Liu, Qiang Meng, Jian Cang, Huijun Sun, Jinyong Peng, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition June 2014, 42 (6) 996-1007; DOI: https://doi.org/10.1124/dmd.113.055194
  5. Messick, Kirsten

    1. You have access
      Differential Effects of Rifampin and Ketoconazole on the Blood and Liver Concentration of Atorvastatin in Wild-Type and Cyp3a and Oatp1a/b Knockout Mice
      Jae H. Chang, Justin Ly, Emile Plise, Xiaolin Zhang, Kirsten Messick, Matthew Wright and Jonathan Cheong
      Drug Metabolism and Disposition June 2014, 42 (6) 1067-1073; DOI: https://doi.org/10.1124/dmd.114.057968
  6. Metushi, Imir G.

    1. You have access
      Paradoxical Attenuation of Autoimmune Hepatitis by Oral Isoniazid in Wild-Type and N-Acetyltransferase–Deficient Mice
      Imir G. Metushi, Ping Cai, Libia Vega, Denis M. Grant and Jack Uetrecht
      Drug Metabolism and Disposition June 2014, 42 (6) 963-973; DOI: https://doi.org/10.1124/dmd.113.056622
  7. Moeller, Timothy

    1. You have access
      Aldehyde Oxidase Activity in Donor-Matched Fresh and Cryopreserved Human Hepatocytes and Assessment of Variability in 75 Donors
      J. Matthew Hutzler, Young-Sun Yang, Caitlin Brown, Scott Heyward and Timothy Moeller
      Drug Metabolism and Disposition June 2014, 42 (6) 1090-1097; DOI: https://doi.org/10.1124/dmd.114.057984
  8. Mohutsky, Michael A.

    1. You have access
      Investigational Small-Molecule Drug Selectively Suppresses Constitutive CYP2B6 Activity at the Gene Transcription Level: Physiologically Based Pharmacokinetic Model Assessment of Clinical Drug Interaction Risk
      Maciej J. Zamek-Gliszczynski, Michael A. Mohutsky, Jessica L. F. Rehmel and Alice B. Ke
      Drug Metabolism and Disposition June 2014, 42 (6) 1008-1015; DOI: https://doi.org/10.1124/dmd.114.057018
  9. Moore, David J.

    1. You have access
      Metabolic Activation of the Indoloquinazoline Alkaloids Evodiamine and Rutaecarpine by Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4
      Bo Wen, Vikram Roongta, Liling Liu and David J. Moore
      Drug Metabolism and Disposition June 2014, 42 (6) 1044-1054; DOI: https://doi.org/10.1124/dmd.114.057414
  10. Morikawa, Yoshio

    1. You have access
      Application of Chimeric Mice with Humanized Liver for Study of Human-Specific Drug Metabolism
      Thomas J. Bateman, Vijay G.B. Reddy, Masakazu Kakuni, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition June 2014, 42 (6) 1055-1065; DOI: https://doi.org/10.1124/dmd.114.056978
  11. Munemasa, Toshiko

    1. You have access
      Identification of Bioactivating Enzymes Involved in the Hydrolysis of Laninamivir Octanoate, a Long-Acting Neuraminidase Inhibitor, in Human Pulmonary Tissue
      Kumiko Koyama, Yuji Ogura, Daisuke Nakai, Mihoko Watanabe, Toshiko Munemasa, Yuka Oofune, Kazuishi Kubota, Akira Shinagawa and Takashi Izumi
      Drug Metabolism and Disposition June 2014, 42 (6) 1031-1038; DOI: https://doi.org/10.1124/dmd.114.057620

N

  1. Nakai, Daisuke

    1. You have access
      Identification of Bioactivating Enzymes Involved in the Hydrolysis of Laninamivir Octanoate, a Long-Acting Neuraminidase Inhibitor, in Human Pulmonary Tissue
      Kumiko Koyama, Yuji Ogura, Daisuke Nakai, Mihoko Watanabe, Toshiko Munemasa, Yuka Oofune, Kazuishi Kubota, Akira Shinagawa and Takashi Izumi
      Drug Metabolism and Disposition June 2014, 42 (6) 1031-1038; DOI: https://doi.org/10.1124/dmd.114.057620
  2. Nakamura, Kenji

    1. You have access
      Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
      Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie and Tetsuya Terasaki
      Drug Metabolism and Disposition June 2014, 42 (6) 1039-1043; DOI: https://doi.org/10.1124/dmd.114.057646
  3. Nguyen, MyTrang

    1. You have access
      Mice Lacking Three Loci Encoding 14 Glutathione Transferase Genes: A Novel Tool for Assigning Function to the GSTP, GSTM, and GSTT Families
      Zhidan Xiang, John N. Snouwaert, Martina Kovarova, MyTrang Nguyen, Peter W. Repenning, Anne M. Latour, Jaime M. Cyphert and Beverly H. Koller
      Drug Metabolism and Disposition June 2014, 42 (6) 1074-1083; DOI: https://doi.org/10.1124/dmd.113.056481

O

  1. Obuchi, Wataru

    1. You have access
      Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
      Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie and Tetsuya Terasaki
      Drug Metabolism and Disposition June 2014, 42 (6) 1039-1043; DOI: https://doi.org/10.1124/dmd.114.057646
  2. Ogura, Yuji

    1. You have access
      Identification of Bioactivating Enzymes Involved in the Hydrolysis of Laninamivir Octanoate, a Long-Acting Neuraminidase Inhibitor, in Human Pulmonary Tissue
      Kumiko Koyama, Yuji Ogura, Daisuke Nakai, Mihoko Watanabe, Toshiko Munemasa, Yuka Oofune, Kazuishi Kubota, Akira Shinagawa and Takashi Izumi
      Drug Metabolism and Disposition June 2014, 42 (6) 1031-1038; DOI: https://doi.org/10.1124/dmd.114.057620
  3. Ohtsuki, Sumio

    1. You have access
      Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
      Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie and Tetsuya Terasaki
      Drug Metabolism and Disposition June 2014, 42 (6) 1039-1043; DOI: https://doi.org/10.1124/dmd.114.057646
  4. Oofune, Yuka

    1. You have access
      Identification of Bioactivating Enzymes Involved in the Hydrolysis of Laninamivir Octanoate, a Long-Acting Neuraminidase Inhibitor, in Human Pulmonary Tissue
      Kumiko Koyama, Yuji Ogura, Daisuke Nakai, Mihoko Watanabe, Toshiko Munemasa, Yuka Oofune, Kazuishi Kubota, Akira Shinagawa and Takashi Izumi
      Drug Metabolism and Disposition June 2014, 42 (6) 1031-1038; DOI: https://doi.org/10.1124/dmd.114.057620

P

  1. Peng, Jinyong

    1. You have access
      Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat
      Chong Wang, Changyuan Wang, Qi Liu, Qiang Meng, Jian Cang, Huijun Sun, Jinyong Peng, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition June 2014, 42 (6) 996-1007; DOI: https://doi.org/10.1124/dmd.113.055194
  2. Plise, Emile

    1. You have access
      Differential Effects of Rifampin and Ketoconazole on the Blood and Liver Concentration of Atorvastatin in Wild-Type and Cyp3a and Oatp1a/b Knockout Mice
      Jae H. Chang, Justin Ly, Emile Plise, Xiaolin Zhang, Kirsten Messick, Matthew Wright and Jonathan Cheong
      Drug Metabolism and Disposition June 2014, 42 (6) 1067-1073; DOI: https://doi.org/10.1124/dmd.114.057968

R

  1. Reddy, Vijay G.B.

    1. You have access
      Application of Chimeric Mice with Humanized Liver for Study of Human-Specific Drug Metabolism
      Thomas J. Bateman, Vijay G.B. Reddy, Masakazu Kakuni, Yoshio Morikawa and Sanjeev Kumar
      Drug Metabolism and Disposition June 2014, 42 (6) 1055-1065; DOI: https://doi.org/10.1124/dmd.114.056978
  2. Rehmel, Jessica L. F.

    1. You have access
      Investigational Small-Molecule Drug Selectively Suppresses Constitutive CYP2B6 Activity at the Gene Transcription Level: Physiologically Based Pharmacokinetic Model Assessment of Clinical Drug Interaction Risk
      Maciej J. Zamek-Gliszczynski, Michael A. Mohutsky, Jessica L. F. Rehmel and Alice B. Ke
      Drug Metabolism and Disposition June 2014, 42 (6) 1008-1015; DOI: https://doi.org/10.1124/dmd.114.057018
  3. Repenning, Peter W.

    1. You have access
      Mice Lacking Three Loci Encoding 14 Glutathione Transferase Genes: A Novel Tool for Assigning Function to the GSTP, GSTM, and GSTT Families
      Zhidan Xiang, John N. Snouwaert, Martina Kovarova, MyTrang Nguyen, Peter W. Repenning, Anne M. Latour, Jaime M. Cyphert and Beverly H. Koller
      Drug Metabolism and Disposition June 2014, 42 (6) 1074-1083; DOI: https://doi.org/10.1124/dmd.113.056481
  4. Rode, Anja

    1. You have access
      Deletion of 30 Murine Cytochrome P450 Genes Results In Viable Mice With Compromised Drug Metabolism
      Nico Scheer, Lesley A. McLaughlin, Anja Rode, A. Kenneth MacLeod, Colin J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition June 2014, 42 (6) 1022-1030; DOI: https://doi.org/10.1124/dmd.114.057885
  5. Roongta, Vikram

    1. You have access
      Metabolic Activation of the Indoloquinazoline Alkaloids Evodiamine and Rutaecarpine by Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4
      Bo Wen, Vikram Roongta, Liling Liu and David J. Moore
      Drug Metabolism and Disposition June 2014, 42 (6) 1044-1054; DOI: https://doi.org/10.1124/dmd.114.057414

S

  1. Scheer, Nico

    1. You have access
      Deletion of 30 Murine Cytochrome P450 Genes Results In Viable Mice With Compromised Drug Metabolism
      Nico Scheer, Lesley A. McLaughlin, Anja Rode, A. Kenneth MacLeod, Colin J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition June 2014, 42 (6) 1022-1030; DOI: https://doi.org/10.1124/dmd.114.057885
  2. Shin, Beom Soo

    1. You have access
      Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor
      Beom Soo Shin, Sun Dong Yoo, Tae Hwan Kim, Jurgen B. Bulitta, Cornelia B. Landersdorfer, Jeong Cheol Shin, Jin Ho Choi, Kwon-Yeon Weon, Sang Hoon Joo and Soyoung Shin
      Drug Metabolism and Disposition June 2014, 42 (6) 974-982; DOI: https://doi.org/10.1124/dmd.113.056713
  3. Shin, Jeong Cheol

    1. You have access
      Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor
      Beom Soo Shin, Sun Dong Yoo, Tae Hwan Kim, Jurgen B. Bulitta, Cornelia B. Landersdorfer, Jeong Cheol Shin, Jin Ho Choi, Kwon-Yeon Weon, Sang Hoon Joo and Soyoung Shin
      Drug Metabolism and Disposition June 2014, 42 (6) 974-982; DOI: https://doi.org/10.1124/dmd.113.056713
  4. Shin, Soyoung

    1. You have access
      Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor
      Beom Soo Shin, Sun Dong Yoo, Tae Hwan Kim, Jurgen B. Bulitta, Cornelia B. Landersdorfer, Jeong Cheol Shin, Jin Ho Choi, Kwon-Yeon Weon, Sang Hoon Joo and Soyoung Shin
      Drug Metabolism and Disposition June 2014, 42 (6) 974-982; DOI: https://doi.org/10.1124/dmd.113.056713
  5. Shinagawa, Akira

    1. You have access
      Identification of Bioactivating Enzymes Involved in the Hydrolysis of Laninamivir Octanoate, a Long-Acting Neuraminidase Inhibitor, in Human Pulmonary Tissue
      Kumiko Koyama, Yuji Ogura, Daisuke Nakai, Mihoko Watanabe, Toshiko Munemasa, Yuka Oofune, Kazuishi Kubota, Akira Shinagawa and Takashi Izumi
      Drug Metabolism and Disposition June 2014, 42 (6) 1031-1038; DOI: https://doi.org/10.1124/dmd.114.057620
  6. Snouwaert, John N.

    1. You have access
      Mice Lacking Three Loci Encoding 14 Glutathione Transferase Genes: A Novel Tool for Assigning Function to the GSTP, GSTM, and GSTT Families
      Zhidan Xiang, John N. Snouwaert, Martina Kovarova, MyTrang Nguyen, Peter W. Repenning, Anne M. Latour, Jaime M. Cyphert and Beverly H. Koller
      Drug Metabolism and Disposition June 2014, 42 (6) 1074-1083; DOI: https://doi.org/10.1124/dmd.113.056481
  7. Sugiyama, Yuichi

    1. You have access
      Quantitative Investigation of the Brain-to-Cerebrospinal Fluid Unbound Drug Concentration Ratio under Steady-State Conditions in Rats Using a Pharmacokinetic Model and Scaling Factors for Active Efflux Transporters
      Hiroshi Kodaira, Hiroyuki Kusuhara, Eiichi Fuse, Junko Ushiki and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2014, 42 (6) 983-989; DOI: https://doi.org/10.1124/dmd.113.056606
  8. Sun, Huijun

    1. You have access
      Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat
      Chong Wang, Changyuan Wang, Qi Liu, Qiang Meng, Jian Cang, Huijun Sun, Jinyong Peng, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition June 2014, 42 (6) 996-1007; DOI: https://doi.org/10.1124/dmd.113.055194

T

  1. Tateno, Chise

    1. You have access
      Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
      Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie and Tetsuya Terasaki
      Drug Metabolism and Disposition June 2014, 42 (6) 1039-1043; DOI: https://doi.org/10.1124/dmd.114.057646
  2. Terasaki, Tetsuya

    1. You have access
      Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
      Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie and Tetsuya Terasaki
      Drug Metabolism and Disposition June 2014, 42 (6) 1039-1043; DOI: https://doi.org/10.1124/dmd.114.057646

U

  1. Uchida, Yasuo

    1. You have access
      Validation of uPA/SCID Mouse with Humanized Liver as a Human Liver Model: Protein Quantification of Transporters, Cytochromes P450, and UDP-Glucuronosyltransferases by LC-MS/MS
      Sumio Ohtsuki, Hirotaka Kawakami, Tae Inoue, Kenji Nakamura, Chise Tateno, Yuki Katsukura, Wataru Obuchi, Yasuo Uchida, Junichi Kamiie, Toru Horie and Tetsuya Terasaki
      Drug Metabolism and Disposition June 2014, 42 (6) 1039-1043; DOI: https://doi.org/10.1124/dmd.114.057646
  2. Uetrecht, Jack

    1. You have access
      Paradoxical Attenuation of Autoimmune Hepatitis by Oral Isoniazid in Wild-Type and N-Acetyltransferase–Deficient Mice
      Imir G. Metushi, Ping Cai, Libia Vega, Denis M. Grant and Jack Uetrecht
      Drug Metabolism and Disposition June 2014, 42 (6) 963-973; DOI: https://doi.org/10.1124/dmd.113.056622
  3. Ushiki, Junko

    1. You have access
      Quantitative Investigation of the Brain-to-Cerebrospinal Fluid Unbound Drug Concentration Ratio under Steady-State Conditions in Rats Using a Pharmacokinetic Model and Scaling Factors for Active Efflux Transporters
      Hiroshi Kodaira, Hiroyuki Kusuhara, Eiichi Fuse, Junko Ushiki and Yuichi Sugiyama
      Drug Metabolism and Disposition June 2014, 42 (6) 983-989; DOI: https://doi.org/10.1124/dmd.113.056606

V

  1. Vega, Libia

    1. You have access
      Paradoxical Attenuation of Autoimmune Hepatitis by Oral Isoniazid in Wild-Type and N-Acetyltransferase–Deficient Mice
      Imir G. Metushi, Ping Cai, Libia Vega, Denis M. Grant and Jack Uetrecht
      Drug Metabolism and Disposition June 2014, 42 (6) 963-973; DOI: https://doi.org/10.1124/dmd.113.056622

W

  1. Wang, Changyuan

    1. You have access
      Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat
      Chong Wang, Changyuan Wang, Qi Liu, Qiang Meng, Jian Cang, Huijun Sun, Jinyong Peng, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition June 2014, 42 (6) 996-1007; DOI: https://doi.org/10.1124/dmd.113.055194
  2. Wang, Chong

    1. You have access
      Aspirin and Probenecid Inhibit Organic Anion Transporter 3–Mediated Renal Uptake of Cilostazol and Probenecid Induces Metabolism of Cilostazol in the Rat
      Chong Wang, Changyuan Wang, Qi Liu, Qiang Meng, Jian Cang, Huijun Sun, Jinyong Peng, Xiaochi Ma, Xiaokui Huo and Kexin Liu
      Drug Metabolism and Disposition June 2014, 42 (6) 996-1007; DOI: https://doi.org/10.1124/dmd.113.055194
  3. Watanabe, Mihoko

    1. You have access
      Identification of Bioactivating Enzymes Involved in the Hydrolysis of Laninamivir Octanoate, a Long-Acting Neuraminidase Inhibitor, in Human Pulmonary Tissue
      Kumiko Koyama, Yuji Ogura, Daisuke Nakai, Mihoko Watanabe, Toshiko Munemasa, Yuka Oofune, Kazuishi Kubota, Akira Shinagawa and Takashi Izumi
      Drug Metabolism and Disposition June 2014, 42 (6) 1031-1038; DOI: https://doi.org/10.1124/dmd.114.057620
  4. Weidolf, Lars

    1. You have access
      Systemic Exposure to the Metabolites of Lesogaberan in Humans and Animals: A Case Study of Metabolites in Safety Testing
      Ann Aurell Holmberg, Anja Ekdahl and Lars Weidolf
      Drug Metabolism and Disposition June 2014, 42 (6) 1016-1021; DOI: https://doi.org/10.1124/dmd.113.056614
  5. Wen, Bo

    1. You have access
      Metabolic Activation of the Indoloquinazoline Alkaloids Evodiamine and Rutaecarpine by Human Liver Microsomes: Dehydrogenation and Inactivation of Cytochrome P450 3A4
      Bo Wen, Vikram Roongta, Liling Liu and David J. Moore
      Drug Metabolism and Disposition June 2014, 42 (6) 1044-1054; DOI: https://doi.org/10.1124/dmd.114.057414
  6. Weon, Kwon-Yeon

    1. You have access
      Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor
      Beom Soo Shin, Sun Dong Yoo, Tae Hwan Kim, Jurgen B. Bulitta, Cornelia B. Landersdorfer, Jeong Cheol Shin, Jin Ho Choi, Kwon-Yeon Weon, Sang Hoon Joo and Soyoung Shin
      Drug Metabolism and Disposition June 2014, 42 (6) 974-982; DOI: https://doi.org/10.1124/dmd.113.056713
  7. Wolf, C. Roland

    1. You have access
      Deletion of 30 Murine Cytochrome P450 Genes Results In Viable Mice With Compromised Drug Metabolism
      Nico Scheer, Lesley A. McLaughlin, Anja Rode, A. Kenneth MacLeod, Colin J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition June 2014, 42 (6) 1022-1030; DOI: https://doi.org/10.1124/dmd.114.057885
  8. Wright, Matthew

    1. You have access
      Differential Effects of Rifampin and Ketoconazole on the Blood and Liver Concentration of Atorvastatin in Wild-Type and Cyp3a and Oatp1a/b Knockout Mice
      Jae H. Chang, Justin Ly, Emile Plise, Xiaolin Zhang, Kirsten Messick, Matthew Wright and Jonathan Cheong
      Drug Metabolism and Disposition June 2014, 42 (6) 1067-1073; DOI: https://doi.org/10.1124/dmd.114.057968

X

  1. Xiang, Zhidan

    1. You have access
      Mice Lacking Three Loci Encoding 14 Glutathione Transferase Genes: A Novel Tool for Assigning Function to the GSTP, GSTM, and GSTT Families
      Zhidan Xiang, John N. Snouwaert, Martina Kovarova, MyTrang Nguyen, Peter W. Repenning, Anne M. Latour, Jaime M. Cyphert and Beverly H. Koller
      Drug Metabolism and Disposition June 2014, 42 (6) 1074-1083; DOI: https://doi.org/10.1124/dmd.113.056481

Y

  1. Yang, Young-Sun

    1. You have access
      Aldehyde Oxidase Activity in Donor-Matched Fresh and Cryopreserved Human Hepatocytes and Assessment of Variability in 75 Donors
      J. Matthew Hutzler, Young-Sun Yang, Caitlin Brown, Scott Heyward and Timothy Moeller
      Drug Metabolism and Disposition June 2014, 42 (6) 1090-1097; DOI: https://doi.org/10.1124/dmd.114.057984
  2. Yatsu, Tomofumi

    1. You have access
      Nigramide C Is a Natural Agonist of Human Pregnane X Receptor
      Yuichiro Kanno, Tomofumi Yatsu, Wei Li, Kazuo Koike and Yoshio Inouye
      Drug Metabolism and Disposition June 2014, 42 (6) 1084-1089; DOI: https://doi.org/10.1124/dmd.114.057810
  3. Yoo, Sun Dong

    1. You have access
      Quantitative Determination of Absorption and First-Pass Metabolism of Apicidin, a Potent Histone Deacetylase Inhibitor
      Beom Soo Shin, Sun Dong Yoo, Tae Hwan Kim, Jurgen B. Bulitta, Cornelia B. Landersdorfer, Jeong Cheol Shin, Jin Ho Choi, Kwon-Yeon Weon, Sang Hoon Joo and Soyoung Shin
      Drug Metabolism and Disposition June 2014, 42 (6) 974-982; DOI: https://doi.org/10.1124/dmd.113.056713

Z

  1. Zamek-Gliszczynski, Maciej J.

    1. You have access
      Investigational Small-Molecule Drug Selectively Suppresses Constitutive CYP2B6 Activity at the Gene Transcription Level: Physiologically Based Pharmacokinetic Model Assessment of Clinical Drug Interaction Risk
      Maciej J. Zamek-Gliszczynski, Michael A. Mohutsky, Jessica L. F. Rehmel and Alice B. Ke
      Drug Metabolism and Disposition June 2014, 42 (6) 1008-1015; DOI: https://doi.org/10.1124/dmd.114.057018
  2. Zhang, Xiaolin

    1. You have access
      Differential Effects of Rifampin and Ketoconazole on the Blood and Liver Concentration of Atorvastatin in Wild-Type and Cyp3a and Oatp1a/b Knockout Mice
      Jae H. Chang, Justin Ly, Emile Plise, Xiaolin Zhang, Kirsten Messick, Matthew Wright and Jonathan Cheong
      Drug Metabolism and Disposition June 2014, 42 (6) 1067-1073; DOI: https://doi.org/10.1124/dmd.114.057968
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Drug Metabolism and Disposition: 42 (6)
Drug Metabolism and Disposition
Vol. 42, Issue 6
1 Jun 2014
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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