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Research ArticleArticle

Aldehyde Oxidase Activity in Donor-Matched Fresh and Cryopreserved Human Hepatocytes and Assessment of Variability in 75 Donors

J. Matthew Hutzler, Young-Sun Yang, Caitlin Brown, Scott Heyward and Timothy Moeller
Drug Metabolism and Disposition June 2014, 42 (6) 1090-1097; DOI: https://doi.org/10.1124/dmd.114.057984

Article Information

vol. 42 no. 6 1090-1097
DOI 
https://doi.org/10.1124/dmd.114.057984
PubMed 
24713130
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 5, 2014
  • Accepted April 8, 2014
  • Published online May 5, 2014.

Article Versions

Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. J. Matthew Hutzler,
  2. Young-Sun Yang,
  3. Caitlin Brown,
  4. Scott Heyward, and
  5. Timothy Moeller
  1. Boehringer-Ingelheim Pharmaceuticals Inc. Medicinal Chemistry, Drug Discovery Support (DMPK), Ridgefield, Connecticut (J.M.H., Y.S.Y.), BioreclamationIVT, Baltimore, Maryland (C.B., S.H., T.M.)
  1. Address correspondence to:
    Dr. J. Matthew Hutzler, Boehringer-Ingelheim Pharmaceuticals Inc., Drug Discovery Support, 175 Briar Ridge Road, R&D 10578, Ridgefield, CT 06877. E-mail: matt.hutzler{at}boehringer-ingelheim.com
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Research ArticleArticle

Aldehyde Oxidase Activity in Human Hepatocytes

J. Matthew Hutzler, Young-Sun Yang, Caitlin Brown, Scott Heyward and Timothy Moeller
Drug Metabolism and Disposition June 1, 2014, 42 (6) 1090-1097; DOI: https://doi.org/10.1124/dmd.114.057984
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