Drug Metabolism and Disposition: 42 (7)

Cover Caption

About the cover: Distribution of pictilisib in U87 tumor (A, animal 2) and GNE-317 in U87 (B, animal 6) and GS2 (C, animal 12) tumors and drug distribution ratios. See the article by Salphati et al., (dx.doi.org/10.1124/dmd.114.057513).

In this issue

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUC_I/AUC) RATIOS
In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”

More...

Main menu

User menu

Search

Cover Caption

In this issue

Jump to

Navigate

More Information

ASPET's Other Journals