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Drug Metabolism & Disposition

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  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
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Index by author

July 01, 2014; Volume 42,Issue 7
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Alicke, Bruno

    1. You have access
      Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging
      Laurent Salphati, Sheerin Shahidi-Latham, Cristine Quiason, Kai Barck, Merry Nishimura, Bruno Alicke, Jodie Pang, Richard A. Carano, Alan G. Olivero and Heidi S. Phillips
      Drug Metabolism and Disposition July 2014, 42 (7) 1110-1116; DOI: https://doi.org/10.1124/dmd.114.057513
  2. Artursson, Per

    1. You have access
      Hepatic Uptake of Atorvastatin: Influence of Variability in Transporter Expression on Uptake Clearance and Drug-Drug InteractionsGraphic
      Anna Vildhede, Maria Karlgren, Elin K. Svedberg, Jacek R. Wisniewski, Yurong Lai, Agneta Norén and Per Artursson
      Drug Metabolism and Disposition July 2014, 42 (7) 1210-1218; DOI: https://doi.org/10.1124/dmd.113.056309

B

  1. Backman, Janne T.

    1. You have access
      In Vitro Assessment of Time-Dependent Inhibitory Effects on CYP2C8 and CYP3A Activity by Fourteen Protein Kinase Inhibitors
      Anne M. Filppula, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition July 2014, 42 (7) 1202-1209; DOI: https://doi.org/10.1124/dmd.114.057695
  2. Badolo, Lassina

    1. You have access
      Identification of a Functional Homolog of the Mammalian CYP3A4 in Locusts
      Line Rørbæk Olsen, Charlotte Gabel-Jensen, Peter Aadal Nielsen, Steen Honoré Hansen and Lassina Badolo
      Drug Metabolism and Disposition July 2014, 42 (7) 1153-1162; DOI: https://doi.org/10.1124/dmd.114.057430
  3. Ball, William J.

    1. You have access
      A Recombinant Humanized Anti-Cocaine Monoclonal Antibody Inhibits the Distribution of Cocaine to the Brain in Rats
      Andrew B. Norman, Felicia C. T. Gooden, Michael R. Tabet and William J. Ball
      Drug Metabolism and Disposition July 2014, 42 (7) 1125-1131; DOI: https://doi.org/10.1124/dmd.114.057034
  4. Barck, Kai

    1. You have access
      Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging
      Laurent Salphati, Sheerin Shahidi-Latham, Cristine Quiason, Kai Barck, Merry Nishimura, Bruno Alicke, Jodie Pang, Richard A. Carano, Alan G. Olivero and Heidi S. Phillips
      Drug Metabolism and Disposition July 2014, 42 (7) 1110-1116; DOI: https://doi.org/10.1124/dmd.114.057513
  5. Bowen, Chet

    1. You have access
      The Metabolic Drug-Drug Interaction Profile of Dabrafenib: In Vitro Investigations and Quantitative Extrapolation of the P450-Mediated DDI Risk
      Sarah K. Lawrence, Dung Nguyen, Chet Bowen, Lauren Richards-Peterson and Konstantine W. Skordos
      Drug Metabolism and Disposition July 2014, 42 (7) 1180-1190; DOI: https://doi.org/10.1124/dmd.114.057778
  6. Brouwer, Kim L. R.

    1. You have access
      Hepatocellular Exposure of Troglitazone Metabolites in Rat Sandwich-Cultured Hepatocytes Lacking Bcrp and Mrp2: Interplay between Formation and Excretion
      Kyunghee Yang and Kim L. R. Brouwer
      Drug Metabolism and Disposition July 2014, 42 (7) 1219-1226; DOI: https://doi.org/10.1124/dmd.114.057190
  7. Buckpitt, Alan R.

    1. You have access
      Metabolic Activation of the Antibacterial Agent Triclocarban by Cytochrome P450 1A1 Yielding Glutathione Adducts
      Nils Helge Schebb, Jaya B. Muvvala, Dexter Morin, Alan R. Buckpitt, Bruce D. Hammock and Robert H. Rice
      Drug Metabolism and Disposition July 2014, 42 (7) 1098-1102; DOI: https://doi.org/10.1124/dmd.114.058206

C

  1. Callahan, Shellie M.

    1. You have access
      Evaluation of the HC-04 Cell Line as an In Vitro Model for Mechanistic Assessment of Changes in Hepatic Cytochrome P450 3A during Adenovirus Infection
      Piyanuch Wonganan, Kristina Jonsson-Schmunk, Shellie M. Callahan, Jin Huk Choi and Maria A. Croyle
      Drug Metabolism and Disposition July 2014, 42 (7) 1191-1201; DOI: https://doi.org/10.1124/dmd.113.056663
  2. Carano, Richard A.

    1. You have access
      Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging
      Laurent Salphati, Sheerin Shahidi-Latham, Cristine Quiason, Kai Barck, Merry Nishimura, Bruno Alicke, Jodie Pang, Richard A. Carano, Alan G. Olivero and Heidi S. Phillips
      Drug Metabolism and Disposition July 2014, 42 (7) 1110-1116; DOI: https://doi.org/10.1124/dmd.114.057513
  3. Cho, Joo-Youn

    1. You have access
      Effects of Proton Pump Inhibitors on Metformin Pharmacokinetics and Pharmacodynamics
      AnHye Kim, Inbum Chung, Seo Hyun Yoon, Kyung-Sang Yu, Kyoung Soo Lim, Joo-Youn Cho, Howard Lee, In-Jin Jang and Jae Yong Chung
      Drug Metabolism and Disposition July 2014, 42 (7) 1174-1179; DOI: https://doi.org/10.1124/dmd.113.055616
  4. Choi, Jin Huk

    1. You have access
      Evaluation of the HC-04 Cell Line as an In Vitro Model for Mechanistic Assessment of Changes in Hepatic Cytochrome P450 3A during Adenovirus Infection
      Piyanuch Wonganan, Kristina Jonsson-Schmunk, Shellie M. Callahan, Jin Huk Choi and Maria A. Croyle
      Drug Metabolism and Disposition July 2014, 42 (7) 1191-1201; DOI: https://doi.org/10.1124/dmd.113.056663
  5. Chung, Inbum

    1. You have access
      Effects of Proton Pump Inhibitors on Metformin Pharmacokinetics and Pharmacodynamics
      AnHye Kim, Inbum Chung, Seo Hyun Yoon, Kyung-Sang Yu, Kyoung Soo Lim, Joo-Youn Cho, Howard Lee, In-Jin Jang and Jae Yong Chung
      Drug Metabolism and Disposition July 2014, 42 (7) 1174-1179; DOI: https://doi.org/10.1124/dmd.113.055616
  6. Chung, Jae Yong

    1. You have access
      Effects of Proton Pump Inhibitors on Metformin Pharmacokinetics and Pharmacodynamics
      AnHye Kim, Inbum Chung, Seo Hyun Yoon, Kyung-Sang Yu, Kyoung Soo Lim, Joo-Youn Cho, Howard Lee, In-Jin Jang and Jae Yong Chung
      Drug Metabolism and Disposition July 2014, 42 (7) 1174-1179; DOI: https://doi.org/10.1124/dmd.113.055616
  7. Croyle, Maria A.

    1. You have access
      Evaluation of the HC-04 Cell Line as an In Vitro Model for Mechanistic Assessment of Changes in Hepatic Cytochrome P450 3A during Adenovirus Infection
      Piyanuch Wonganan, Kristina Jonsson-Schmunk, Shellie M. Callahan, Jin Huk Choi and Maria A. Croyle
      Drug Metabolism and Disposition July 2014, 42 (7) 1191-1201; DOI: https://doi.org/10.1124/dmd.113.056663

F

  1. Filppula, Anne M.

    1. You have access
      In Vitro Assessment of Time-Dependent Inhibitory Effects on CYP2C8 and CYP3A Activity by Fourteen Protein Kinase Inhibitors
      Anne M. Filppula, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition July 2014, 42 (7) 1202-1209; DOI: https://doi.org/10.1124/dmd.114.057695
  2. Fujiwara, Ryoichi

    1. You have access
      Glucuronidation of Drugs and Drug-Induced Toxicity in Humanized UDP-Glucuronosyltransferase 1 Mice
      Yuki Kutsuno, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2014, 42 (7) 1146-1152; DOI: https://doi.org/10.1124/dmd.114.057083
  3. Fukami, Tatsuki

    1. You have access
      Screening of Specific Inhibitors for Human Carboxylesterases or Arylacetamide Deacetylase
      Mai Shimizu, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2014, 42 (7) 1103-1109; DOI: https://doi.org/10.1124/dmd.114.056994

G

  1. Gabel-Jensen, Charlotte

    1. You have access
      Identification of a Functional Homolog of the Mammalian CYP3A4 in Locusts
      Line Rørbæk Olsen, Charlotte Gabel-Jensen, Peter Aadal Nielsen, Steen Honoré Hansen and Lassina Badolo
      Drug Metabolism and Disposition July 2014, 42 (7) 1153-1162; DOI: https://doi.org/10.1124/dmd.114.057430
  2. Gates, Leah A.

    1. You have access
      Comparative Metabolism of Furan in Rodent and Human Cryopreserved Hepatocytes
      Leah A. Gates, Martin B. Phillips, Brock A. Matter and Lisa A. Peterson
      Drug Metabolism and Disposition July 2014, 42 (7) 1132-1136; DOI: https://doi.org/10.1124/dmd.114.057794
  3. Gooden, Felicia C. T.

    1. You have access
      A Recombinant Humanized Anti-Cocaine Monoclonal Antibody Inhibits the Distribution of Cocaine to the Brain in Rats
      Andrew B. Norman, Felicia C. T. Gooden, Michael R. Tabet and William J. Ball
      Drug Metabolism and Disposition July 2014, 42 (7) 1125-1131; DOI: https://doi.org/10.1124/dmd.114.057034
  4. Goosen, Theunis C.

    1. You have access
      Relative Contributions of Cytochrome CYP3A4 Versus CYP3A5 for CYP3A-Cleared Drugs Assessed In Vitro Using a CYP3A4-Selective Inactivator (CYP3cide)
      Elaine Tseng, Robert L. Walsky, Ricardo A. Luzietti, Jennifer J. Harris, Rachel E. Kosa, Theunis C. Goosen, Michael A. Zientek and R. Scott Obach
      Drug Metabolism and Disposition July 2014, 42 (7) 1163-1173; DOI: https://doi.org/10.1124/dmd.114.057000

H

  1. Hagihara, Katsunobu

    1. You have access
      Hepatic Microsomal Thiol Methyltransferase Is Involved in Stereoselective Methylation of Pharmacologically Active Metabolite of Prasugrel
      Miho Kazui, Katsunobu Hagihara, Takashi Izumi, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition July 2014, 42 (7) 1138-1145; DOI: https://doi.org/10.1124/dmd.114.057661
  2. Hammock, Bruce D.

    1. You have access
      Metabolic Activation of the Antibacterial Agent Triclocarban by Cytochrome P450 1A1 Yielding Glutathione Adducts
      Nils Helge Schebb, Jaya B. Muvvala, Dexter Morin, Alan R. Buckpitt, Bruce D. Hammock and Robert H. Rice
      Drug Metabolism and Disposition July 2014, 42 (7) 1098-1102; DOI: https://doi.org/10.1124/dmd.114.058206
  3. Hansen, Steen Honoré

    1. You have access
      Identification of a Functional Homolog of the Mammalian CYP3A4 in Locusts
      Line Rørbæk Olsen, Charlotte Gabel-Jensen, Peter Aadal Nielsen, Steen Honoré Hansen and Lassina Badolo
      Drug Metabolism and Disposition July 2014, 42 (7) 1153-1162; DOI: https://doi.org/10.1124/dmd.114.057430
  4. Harris, Jennifer J.

    1. You have access
      Relative Contributions of Cytochrome CYP3A4 Versus CYP3A5 for CYP3A-Cleared Drugs Assessed In Vitro Using a CYP3A4-Selective Inactivator (CYP3cide)
      Elaine Tseng, Robert L. Walsky, Ricardo A. Luzietti, Jennifer J. Harris, Rachel E. Kosa, Theunis C. Goosen, Michael A. Zientek and R. Scott Obach
      Drug Metabolism and Disposition July 2014, 42 (7) 1163-1173; DOI: https://doi.org/10.1124/dmd.114.057000

I

  1. Ikeda, Toshihiko

    1. You have access
      Hepatic Microsomal Thiol Methyltransferase Is Involved in Stereoselective Methylation of Pharmacologically Active Metabolite of Prasugrel
      Miho Kazui, Katsunobu Hagihara, Takashi Izumi, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition July 2014, 42 (7) 1138-1145; DOI: https://doi.org/10.1124/dmd.114.057661
  2. Itoh, Tomoo

    1. You have access
      Glucuronidation of Drugs and Drug-Induced Toxicity in Humanized UDP-Glucuronosyltransferase 1 Mice
      Yuki Kutsuno, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2014, 42 (7) 1146-1152; DOI: https://doi.org/10.1124/dmd.114.057083
  3. Izumi, Takashi

    1. You have access
      Hepatic Microsomal Thiol Methyltransferase Is Involved in Stereoselective Methylation of Pharmacologically Active Metabolite of Prasugrel
      Miho Kazui, Katsunobu Hagihara, Takashi Izumi, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition July 2014, 42 (7) 1138-1145; DOI: https://doi.org/10.1124/dmd.114.057661

J

  1. Jang, In-Jin

    1. You have access
      Effects of Proton Pump Inhibitors on Metformin Pharmacokinetics and Pharmacodynamics
      AnHye Kim, Inbum Chung, Seo Hyun Yoon, Kyung-Sang Yu, Kyoung Soo Lim, Joo-Youn Cho, Howard Lee, In-Jin Jang and Jae Yong Chung
      Drug Metabolism and Disposition July 2014, 42 (7) 1174-1179; DOI: https://doi.org/10.1124/dmd.113.055616
  2. Jiang, Huidi

    1. You have access
      The Contribution of Human OCT1, OCT3, and CYP3A4 to Nitidine Chloride–Induced Hepatocellular Toxicity
      Liping Li, Meijuan Tu, Xi Yang, Siyuan Sun, Xiaodan Wu, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition July 2014, 42 (7) 1227-1234; DOI: https://doi.org/10.1124/dmd.113.056689
  3. Jonsson-Schmunk, Kristina

    1. You have access
      Evaluation of the HC-04 Cell Line as an In Vitro Model for Mechanistic Assessment of Changes in Hepatic Cytochrome P450 3A during Adenovirus Infection
      Piyanuch Wonganan, Kristina Jonsson-Schmunk, Shellie M. Callahan, Jin Huk Choi and Maria A. Croyle
      Drug Metabolism and Disposition July 2014, 42 (7) 1191-1201; DOI: https://doi.org/10.1124/dmd.113.056663

K

  1. Karlgren, Maria

    1. You have access
      Hepatic Uptake of Atorvastatin: Influence of Variability in Transporter Expression on Uptake Clearance and Drug-Drug InteractionsGraphic
      Anna Vildhede, Maria Karlgren, Elin K. Svedberg, Jacek R. Wisniewski, Yurong Lai, Agneta Norén and Per Artursson
      Drug Metabolism and Disposition July 2014, 42 (7) 1210-1218; DOI: https://doi.org/10.1124/dmd.113.056309
  2. Kazui, Miho

    1. You have access
      Hepatic Microsomal Thiol Methyltransferase Is Involved in Stereoselective Methylation of Pharmacologically Active Metabolite of Prasugrel
      Miho Kazui, Katsunobu Hagihara, Takashi Izumi, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition July 2014, 42 (7) 1138-1145; DOI: https://doi.org/10.1124/dmd.114.057661
  3. Kim, AnHye

    1. You have access
      Effects of Proton Pump Inhibitors on Metformin Pharmacokinetics and Pharmacodynamics
      AnHye Kim, Inbum Chung, Seo Hyun Yoon, Kyung-Sang Yu, Kyoung Soo Lim, Joo-Youn Cho, Howard Lee, In-Jin Jang and Jae Yong Chung
      Drug Metabolism and Disposition July 2014, 42 (7) 1174-1179; DOI: https://doi.org/10.1124/dmd.113.055616
  4. Kosa, Rachel E.

    1. You have access
      Relative Contributions of Cytochrome CYP3A4 Versus CYP3A5 for CYP3A-Cleared Drugs Assessed In Vitro Using a CYP3A4-Selective Inactivator (CYP3cide)
      Elaine Tseng, Robert L. Walsky, Ricardo A. Luzietti, Jennifer J. Harris, Rachel E. Kosa, Theunis C. Goosen, Michael A. Zientek and R. Scott Obach
      Drug Metabolism and Disposition July 2014, 42 (7) 1163-1173; DOI: https://doi.org/10.1124/dmd.114.057000
  5. Kurihara, Atsushi

    1. You have access
      Hepatic Microsomal Thiol Methyltransferase Is Involved in Stereoselective Methylation of Pharmacologically Active Metabolite of Prasugrel
      Miho Kazui, Katsunobu Hagihara, Takashi Izumi, Toshihiko Ikeda and Atsushi Kurihara
      Drug Metabolism and Disposition July 2014, 42 (7) 1138-1145; DOI: https://doi.org/10.1124/dmd.114.057661
  6. Kutsuno, Yuki

    1. You have access
      Glucuronidation of Drugs and Drug-Induced Toxicity in Humanized UDP-Glucuronosyltransferase 1 Mice
      Yuki Kutsuno, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2014, 42 (7) 1146-1152; DOI: https://doi.org/10.1124/dmd.114.057083

L

  1. Lai, Yurong

    1. You have access
      Hepatic Uptake of Atorvastatin: Influence of Variability in Transporter Expression on Uptake Clearance and Drug-Drug InteractionsGraphic
      Anna Vildhede, Maria Karlgren, Elin K. Svedberg, Jacek R. Wisniewski, Yurong Lai, Agneta Norén and Per Artursson
      Drug Metabolism and Disposition July 2014, 42 (7) 1210-1218; DOI: https://doi.org/10.1124/dmd.113.056309
  2. Lavan, Paul

    1. You have access
      1-Aminobenzotriazole Modulates Oral Drug Pharmacokinetics through Cytochrome P450 Inhibition and Delay of Gastric Emptying in Rats
      Rowan A. Stringer, Eckhard Weber, Bruno Tigani, Paul Lavan, Stephen Medhurst and Bindi Sohal
      Drug Metabolism and Disposition July 2014, 42 (7) 1117-1124; DOI: https://doi.org/10.1124/dmd.113.056408
  3. Lawrence, Sarah K.

    1. You have access
      The Metabolic Drug-Drug Interaction Profile of Dabrafenib: In Vitro Investigations and Quantitative Extrapolation of the P450-Mediated DDI Risk
      Sarah K. Lawrence, Dung Nguyen, Chet Bowen, Lauren Richards-Peterson and Konstantine W. Skordos
      Drug Metabolism and Disposition July 2014, 42 (7) 1180-1190; DOI: https://doi.org/10.1124/dmd.114.057778
  4. Lee, Howard

    1. You have access
      Effects of Proton Pump Inhibitors on Metformin Pharmacokinetics and Pharmacodynamics
      AnHye Kim, Inbum Chung, Seo Hyun Yoon, Kyung-Sang Yu, Kyoung Soo Lim, Joo-Youn Cho, Howard Lee, In-Jin Jang and Jae Yong Chung
      Drug Metabolism and Disposition July 2014, 42 (7) 1174-1179; DOI: https://doi.org/10.1124/dmd.113.055616
  5. Li, Liping

    1. You have access
      The Contribution of Human OCT1, OCT3, and CYP3A4 to Nitidine Chloride–Induced Hepatocellular Toxicity
      Liping Li, Meijuan Tu, Xi Yang, Siyuan Sun, Xiaodan Wu, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition July 2014, 42 (7) 1227-1234; DOI: https://doi.org/10.1124/dmd.113.056689
  6. Lim, Kyoung Soo

    1. You have access
      Effects of Proton Pump Inhibitors on Metformin Pharmacokinetics and Pharmacodynamics
      AnHye Kim, Inbum Chung, Seo Hyun Yoon, Kyung-Sang Yu, Kyoung Soo Lim, Joo-Youn Cho, Howard Lee, In-Jin Jang and Jae Yong Chung
      Drug Metabolism and Disposition July 2014, 42 (7) 1174-1179; DOI: https://doi.org/10.1124/dmd.113.055616
  7. Luzietti, Ricardo A.

    1. You have access
      Relative Contributions of Cytochrome CYP3A4 Versus CYP3A5 for CYP3A-Cleared Drugs Assessed In Vitro Using a CYP3A4-Selective Inactivator (CYP3cide)
      Elaine Tseng, Robert L. Walsky, Ricardo A. Luzietti, Jennifer J. Harris, Rachel E. Kosa, Theunis C. Goosen, Michael A. Zientek and R. Scott Obach
      Drug Metabolism and Disposition July 2014, 42 (7) 1163-1173; DOI: https://doi.org/10.1124/dmd.114.057000

M

  1. Matter, Brock A.

    1. You have access
      Comparative Metabolism of Furan in Rodent and Human Cryopreserved Hepatocytes
      Leah A. Gates, Martin B. Phillips, Brock A. Matter and Lisa A. Peterson
      Drug Metabolism and Disposition July 2014, 42 (7) 1132-1136; DOI: https://doi.org/10.1124/dmd.114.057794
  2. Medhurst, Stephen

    1. You have access
      1-Aminobenzotriazole Modulates Oral Drug Pharmacokinetics through Cytochrome P450 Inhibition and Delay of Gastric Emptying in Rats
      Rowan A. Stringer, Eckhard Weber, Bruno Tigani, Paul Lavan, Stephen Medhurst and Bindi Sohal
      Drug Metabolism and Disposition July 2014, 42 (7) 1117-1124; DOI: https://doi.org/10.1124/dmd.113.056408
  3. Morin, Dexter

    1. You have access
      Metabolic Activation of the Antibacterial Agent Triclocarban by Cytochrome P450 1A1 Yielding Glutathione Adducts
      Nils Helge Schebb, Jaya B. Muvvala, Dexter Morin, Alan R. Buckpitt, Bruce D. Hammock and Robert H. Rice
      Drug Metabolism and Disposition July 2014, 42 (7) 1098-1102; DOI: https://doi.org/10.1124/dmd.114.058206
  4. Muvvala, Jaya B.

    1. You have access
      Metabolic Activation of the Antibacterial Agent Triclocarban by Cytochrome P450 1A1 Yielding Glutathione Adducts
      Nils Helge Schebb, Jaya B. Muvvala, Dexter Morin, Alan R. Buckpitt, Bruce D. Hammock and Robert H. Rice
      Drug Metabolism and Disposition July 2014, 42 (7) 1098-1102; DOI: https://doi.org/10.1124/dmd.114.058206

N

  1. Nakajima, Miki

    1. You have access
      Screening of Specific Inhibitors for Human Carboxylesterases or Arylacetamide Deacetylase
      Mai Shimizu, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2014, 42 (7) 1103-1109; DOI: https://doi.org/10.1124/dmd.114.056994
  2. Neuvonen, Pertti J.

    1. You have access
      In Vitro Assessment of Time-Dependent Inhibitory Effects on CYP2C8 and CYP3A Activity by Fourteen Protein Kinase Inhibitors
      Anne M. Filppula, Pertti J. Neuvonen and Janne T. Backman
      Drug Metabolism and Disposition July 2014, 42 (7) 1202-1209; DOI: https://doi.org/10.1124/dmd.114.057695
  3. Nguyen, Dung

    1. You have access
      The Metabolic Drug-Drug Interaction Profile of Dabrafenib: In Vitro Investigations and Quantitative Extrapolation of the P450-Mediated DDI Risk
      Sarah K. Lawrence, Dung Nguyen, Chet Bowen, Lauren Richards-Peterson and Konstantine W. Skordos
      Drug Metabolism and Disposition July 2014, 42 (7) 1180-1190; DOI: https://doi.org/10.1124/dmd.114.057778
  4. Nielsen, Peter Aadal

    1. You have access
      Identification of a Functional Homolog of the Mammalian CYP3A4 in Locusts
      Line Rørbæk Olsen, Charlotte Gabel-Jensen, Peter Aadal Nielsen, Steen Honoré Hansen and Lassina Badolo
      Drug Metabolism and Disposition July 2014, 42 (7) 1153-1162; DOI: https://doi.org/10.1124/dmd.114.057430
  5. Nishimura, Merry

    1. You have access
      Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging
      Laurent Salphati, Sheerin Shahidi-Latham, Cristine Quiason, Kai Barck, Merry Nishimura, Bruno Alicke, Jodie Pang, Richard A. Carano, Alan G. Olivero and Heidi S. Phillips
      Drug Metabolism and Disposition July 2014, 42 (7) 1110-1116; DOI: https://doi.org/10.1124/dmd.114.057513
  6. Norén, Agneta

    1. You have access
      Hepatic Uptake of Atorvastatin: Influence of Variability in Transporter Expression on Uptake Clearance and Drug-Drug InteractionsGraphic
      Anna Vildhede, Maria Karlgren, Elin K. Svedberg, Jacek R. Wisniewski, Yurong Lai, Agneta Norén and Per Artursson
      Drug Metabolism and Disposition July 2014, 42 (7) 1210-1218; DOI: https://doi.org/10.1124/dmd.113.056309
  7. Norman, Andrew B.

    1. You have access
      A Recombinant Humanized Anti-Cocaine Monoclonal Antibody Inhibits the Distribution of Cocaine to the Brain in Rats
      Andrew B. Norman, Felicia C. T. Gooden, Michael R. Tabet and William J. Ball
      Drug Metabolism and Disposition July 2014, 42 (7) 1125-1131; DOI: https://doi.org/10.1124/dmd.114.057034

O

  1. Obach, R. Scott

    1. You have access
      Relative Contributions of Cytochrome CYP3A4 Versus CYP3A5 for CYP3A-Cleared Drugs Assessed In Vitro Using a CYP3A4-Selective Inactivator (CYP3cide)
      Elaine Tseng, Robert L. Walsky, Ricardo A. Luzietti, Jennifer J. Harris, Rachel E. Kosa, Theunis C. Goosen, Michael A. Zientek and R. Scott Obach
      Drug Metabolism and Disposition July 2014, 42 (7) 1163-1173; DOI: https://doi.org/10.1124/dmd.114.057000
  2. Olivero, Alan G.

    1. You have access
      Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging
      Laurent Salphati, Sheerin Shahidi-Latham, Cristine Quiason, Kai Barck, Merry Nishimura, Bruno Alicke, Jodie Pang, Richard A. Carano, Alan G. Olivero and Heidi S. Phillips
      Drug Metabolism and Disposition July 2014, 42 (7) 1110-1116; DOI: https://doi.org/10.1124/dmd.114.057513
  3. Olsen, Line Rørbæk

    1. You have access
      Identification of a Functional Homolog of the Mammalian CYP3A4 in Locusts
      Line Rørbæk Olsen, Charlotte Gabel-Jensen, Peter Aadal Nielsen, Steen Honoré Hansen and Lassina Badolo
      Drug Metabolism and Disposition July 2014, 42 (7) 1153-1162; DOI: https://doi.org/10.1124/dmd.114.057430

P

  1. Pang, Jodie

    1. You have access
      Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging
      Laurent Salphati, Sheerin Shahidi-Latham, Cristine Quiason, Kai Barck, Merry Nishimura, Bruno Alicke, Jodie Pang, Richard A. Carano, Alan G. Olivero and Heidi S. Phillips
      Drug Metabolism and Disposition July 2014, 42 (7) 1110-1116; DOI: https://doi.org/10.1124/dmd.114.057513
  2. Peterson, Lisa A.

    1. You have access
      Comparative Metabolism of Furan in Rodent and Human Cryopreserved Hepatocytes
      Leah A. Gates, Martin B. Phillips, Brock A. Matter and Lisa A. Peterson
      Drug Metabolism and Disposition July 2014, 42 (7) 1132-1136; DOI: https://doi.org/10.1124/dmd.114.057794
  3. Phillips, Heidi S.

    1. You have access
      Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging
      Laurent Salphati, Sheerin Shahidi-Latham, Cristine Quiason, Kai Barck, Merry Nishimura, Bruno Alicke, Jodie Pang, Richard A. Carano, Alan G. Olivero and Heidi S. Phillips
      Drug Metabolism and Disposition July 2014, 42 (7) 1110-1116; DOI: https://doi.org/10.1124/dmd.114.057513
  4. Phillips, Martin B.

    1. You have access
      Comparative Metabolism of Furan in Rodent and Human Cryopreserved Hepatocytes
      Leah A. Gates, Martin B. Phillips, Brock A. Matter and Lisa A. Peterson
      Drug Metabolism and Disposition July 2014, 42 (7) 1132-1136; DOI: https://doi.org/10.1124/dmd.114.057794

Q

  1. Quiason, Cristine

    1. You have access
      Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging
      Laurent Salphati, Sheerin Shahidi-Latham, Cristine Quiason, Kai Barck, Merry Nishimura, Bruno Alicke, Jodie Pang, Richard A. Carano, Alan G. Olivero and Heidi S. Phillips
      Drug Metabolism and Disposition July 2014, 42 (7) 1110-1116; DOI: https://doi.org/10.1124/dmd.114.057513

R

  1. Rice, Robert H.

    1. You have access
      Metabolic Activation of the Antibacterial Agent Triclocarban by Cytochrome P450 1A1 Yielding Glutathione Adducts
      Nils Helge Schebb, Jaya B. Muvvala, Dexter Morin, Alan R. Buckpitt, Bruce D. Hammock and Robert H. Rice
      Drug Metabolism and Disposition July 2014, 42 (7) 1098-1102; DOI: https://doi.org/10.1124/dmd.114.058206
  2. Richards-Peterson, Lauren

    1. You have access
      The Metabolic Drug-Drug Interaction Profile of Dabrafenib: In Vitro Investigations and Quantitative Extrapolation of the P450-Mediated DDI Risk
      Sarah K. Lawrence, Dung Nguyen, Chet Bowen, Lauren Richards-Peterson and Konstantine W. Skordos
      Drug Metabolism and Disposition July 2014, 42 (7) 1180-1190; DOI: https://doi.org/10.1124/dmd.114.057778

S

  1. Salphati, Laurent

    1. You have access
      Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging
      Laurent Salphati, Sheerin Shahidi-Latham, Cristine Quiason, Kai Barck, Merry Nishimura, Bruno Alicke, Jodie Pang, Richard A. Carano, Alan G. Olivero and Heidi S. Phillips
      Drug Metabolism and Disposition July 2014, 42 (7) 1110-1116; DOI: https://doi.org/10.1124/dmd.114.057513
  2. Schebb, Nils Helge

    1. You have access
      Metabolic Activation of the Antibacterial Agent Triclocarban by Cytochrome P450 1A1 Yielding Glutathione Adducts
      Nils Helge Schebb, Jaya B. Muvvala, Dexter Morin, Alan R. Buckpitt, Bruce D. Hammock and Robert H. Rice
      Drug Metabolism and Disposition July 2014, 42 (7) 1098-1102; DOI: https://doi.org/10.1124/dmd.114.058206
  3. Shahidi-Latham, Sheerin

    1. You have access
      Distribution of the Phosphatidylinositol 3-Kinase Inhibitors Pictilisib (GDC-0941) and GNE-317 in U87 and GS2 Intracranial Glioblastoma Models—Assessment by Matrix-Assisted Laser Desorption Ionization Imaging
      Laurent Salphati, Sheerin Shahidi-Latham, Cristine Quiason, Kai Barck, Merry Nishimura, Bruno Alicke, Jodie Pang, Richard A. Carano, Alan G. Olivero and Heidi S. Phillips
      Drug Metabolism and Disposition July 2014, 42 (7) 1110-1116; DOI: https://doi.org/10.1124/dmd.114.057513
  4. Shimizu, Mai

    1. You have access
      Screening of Specific Inhibitors for Human Carboxylesterases or Arylacetamide Deacetylase
      Mai Shimizu, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2014, 42 (7) 1103-1109; DOI: https://doi.org/10.1124/dmd.114.056994
  5. Skordos, Konstantine W.

    1. You have access
      The Metabolic Drug-Drug Interaction Profile of Dabrafenib: In Vitro Investigations and Quantitative Extrapolation of the P450-Mediated DDI Risk
      Sarah K. Lawrence, Dung Nguyen, Chet Bowen, Lauren Richards-Peterson and Konstantine W. Skordos
      Drug Metabolism and Disposition July 2014, 42 (7) 1180-1190; DOI: https://doi.org/10.1124/dmd.114.057778
  6. Sohal, Bindi

    1. You have access
      1-Aminobenzotriazole Modulates Oral Drug Pharmacokinetics through Cytochrome P450 Inhibition and Delay of Gastric Emptying in Rats
      Rowan A. Stringer, Eckhard Weber, Bruno Tigani, Paul Lavan, Stephen Medhurst and Bindi Sohal
      Drug Metabolism and Disposition July 2014, 42 (7) 1117-1124; DOI: https://doi.org/10.1124/dmd.113.056408
  7. Stringer, Rowan A.

    1. You have access
      1-Aminobenzotriazole Modulates Oral Drug Pharmacokinetics through Cytochrome P450 Inhibition and Delay of Gastric Emptying in Rats
      Rowan A. Stringer, Eckhard Weber, Bruno Tigani, Paul Lavan, Stephen Medhurst and Bindi Sohal
      Drug Metabolism and Disposition July 2014, 42 (7) 1117-1124; DOI: https://doi.org/10.1124/dmd.113.056408
  8. Sun, Siyuan

    1. You have access
      The Contribution of Human OCT1, OCT3, and CYP3A4 to Nitidine Chloride–Induced Hepatocellular Toxicity
      Liping Li, Meijuan Tu, Xi Yang, Siyuan Sun, Xiaodan Wu, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition July 2014, 42 (7) 1227-1234; DOI: https://doi.org/10.1124/dmd.113.056689
  9. Svedberg, Elin K.

    1. You have access
      Hepatic Uptake of Atorvastatin: Influence of Variability in Transporter Expression on Uptake Clearance and Drug-Drug InteractionsGraphic
      Anna Vildhede, Maria Karlgren, Elin K. Svedberg, Jacek R. Wisniewski, Yurong Lai, Agneta Norén and Per Artursson
      Drug Metabolism and Disposition July 2014, 42 (7) 1210-1218; DOI: https://doi.org/10.1124/dmd.113.056309

T

  1. Tabet, Michael R.

    1. You have access
      A Recombinant Humanized Anti-Cocaine Monoclonal Antibody Inhibits the Distribution of Cocaine to the Brain in Rats
      Andrew B. Norman, Felicia C. T. Gooden, Michael R. Tabet and William J. Ball
      Drug Metabolism and Disposition July 2014, 42 (7) 1125-1131; DOI: https://doi.org/10.1124/dmd.114.057034
  2. Tigani, Bruno

    1. You have access
      1-Aminobenzotriazole Modulates Oral Drug Pharmacokinetics through Cytochrome P450 Inhibition and Delay of Gastric Emptying in Rats
      Rowan A. Stringer, Eckhard Weber, Bruno Tigani, Paul Lavan, Stephen Medhurst and Bindi Sohal
      Drug Metabolism and Disposition July 2014, 42 (7) 1117-1124; DOI: https://doi.org/10.1124/dmd.113.056408
  3. Tseng, Elaine

    1. You have access
      Relative Contributions of Cytochrome CYP3A4 Versus CYP3A5 for CYP3A-Cleared Drugs Assessed In Vitro Using a CYP3A4-Selective Inactivator (CYP3cide)
      Elaine Tseng, Robert L. Walsky, Ricardo A. Luzietti, Jennifer J. Harris, Rachel E. Kosa, Theunis C. Goosen, Michael A. Zientek and R. Scott Obach
      Drug Metabolism and Disposition July 2014, 42 (7) 1163-1173; DOI: https://doi.org/10.1124/dmd.114.057000
  4. Tu, Meijuan

    1. You have access
      The Contribution of Human OCT1, OCT3, and CYP3A4 to Nitidine Chloride–Induced Hepatocellular Toxicity
      Liping Li, Meijuan Tu, Xi Yang, Siyuan Sun, Xiaodan Wu, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition July 2014, 42 (7) 1227-1234; DOI: https://doi.org/10.1124/dmd.113.056689
  5. Tukey, Robert H.

    1. You have access
      Glucuronidation of Drugs and Drug-Induced Toxicity in Humanized UDP-Glucuronosyltransferase 1 Mice
      Yuki Kutsuno, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2014, 42 (7) 1146-1152; DOI: https://doi.org/10.1124/dmd.114.057083

V

  1. Vildhede, Anna

    1. You have access
      Hepatic Uptake of Atorvastatin: Influence of Variability in Transporter Expression on Uptake Clearance and Drug-Drug InteractionsGraphic
      Anna Vildhede, Maria Karlgren, Elin K. Svedberg, Jacek R. Wisniewski, Yurong Lai, Agneta Norén and Per Artursson
      Drug Metabolism and Disposition July 2014, 42 (7) 1210-1218; DOI: https://doi.org/10.1124/dmd.113.056309

W

  1. Walsky, Robert L.

    1. You have access
      Relative Contributions of Cytochrome CYP3A4 Versus CYP3A5 for CYP3A-Cleared Drugs Assessed In Vitro Using a CYP3A4-Selective Inactivator (CYP3cide)
      Elaine Tseng, Robert L. Walsky, Ricardo A. Luzietti, Jennifer J. Harris, Rachel E. Kosa, Theunis C. Goosen, Michael A. Zientek and R. Scott Obach
      Drug Metabolism and Disposition July 2014, 42 (7) 1163-1173; DOI: https://doi.org/10.1124/dmd.114.057000
  2. Weber, Eckhard

    1. You have access
      1-Aminobenzotriazole Modulates Oral Drug Pharmacokinetics through Cytochrome P450 Inhibition and Delay of Gastric Emptying in Rats
      Rowan A. Stringer, Eckhard Weber, Bruno Tigani, Paul Lavan, Stephen Medhurst and Bindi Sohal
      Drug Metabolism and Disposition July 2014, 42 (7) 1117-1124; DOI: https://doi.org/10.1124/dmd.113.056408
  3. Wisniewski, Jacek R.

    1. You have access
      Hepatic Uptake of Atorvastatin: Influence of Variability in Transporter Expression on Uptake Clearance and Drug-Drug InteractionsGraphic
      Anna Vildhede, Maria Karlgren, Elin K. Svedberg, Jacek R. Wisniewski, Yurong Lai, Agneta Norén and Per Artursson
      Drug Metabolism and Disposition July 2014, 42 (7) 1210-1218; DOI: https://doi.org/10.1124/dmd.113.056309
  4. Wonganan, Piyanuch

    1. You have access
      Evaluation of the HC-04 Cell Line as an In Vitro Model for Mechanistic Assessment of Changes in Hepatic Cytochrome P450 3A during Adenovirus Infection
      Piyanuch Wonganan, Kristina Jonsson-Schmunk, Shellie M. Callahan, Jin Huk Choi and Maria A. Croyle
      Drug Metabolism and Disposition July 2014, 42 (7) 1191-1201; DOI: https://doi.org/10.1124/dmd.113.056663
  5. Wu, Xiaodan

    1. You have access
      The Contribution of Human OCT1, OCT3, and CYP3A4 to Nitidine Chloride–Induced Hepatocellular Toxicity
      Liping Li, Meijuan Tu, Xi Yang, Siyuan Sun, Xiaodan Wu, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition July 2014, 42 (7) 1227-1234; DOI: https://doi.org/10.1124/dmd.113.056689

Y

  1. Yang, Kyunghee

    1. You have access
      Hepatocellular Exposure of Troglitazone Metabolites in Rat Sandwich-Cultured Hepatocytes Lacking Bcrp and Mrp2: Interplay between Formation and Excretion
      Kyunghee Yang and Kim L. R. Brouwer
      Drug Metabolism and Disposition July 2014, 42 (7) 1219-1226; DOI: https://doi.org/10.1124/dmd.114.057190
  2. Yang, Xi

    1. You have access
      The Contribution of Human OCT1, OCT3, and CYP3A4 to Nitidine Chloride–Induced Hepatocellular Toxicity
      Liping Li, Meijuan Tu, Xi Yang, Siyuan Sun, Xiaodan Wu, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition July 2014, 42 (7) 1227-1234; DOI: https://doi.org/10.1124/dmd.113.056689
  3. Yokoi, Tsuyoshi

    1. You have access
      Screening of Specific Inhibitors for Human Carboxylesterases or Arylacetamide Deacetylase
      Mai Shimizu, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2014, 42 (7) 1103-1109; DOI: https://doi.org/10.1124/dmd.114.056994
  4. Yoon, Seo Hyun

    1. You have access
      Effects of Proton Pump Inhibitors on Metformin Pharmacokinetics and Pharmacodynamics
      AnHye Kim, Inbum Chung, Seo Hyun Yoon, Kyung-Sang Yu, Kyoung Soo Lim, Joo-Youn Cho, Howard Lee, In-Jin Jang and Jae Yong Chung
      Drug Metabolism and Disposition July 2014, 42 (7) 1174-1179; DOI: https://doi.org/10.1124/dmd.113.055616
  5. Yu, Kyung-Sang

    1. You have access
      Effects of Proton Pump Inhibitors on Metformin Pharmacokinetics and Pharmacodynamics
      AnHye Kim, Inbum Chung, Seo Hyun Yoon, Kyung-Sang Yu, Kyoung Soo Lim, Joo-Youn Cho, Howard Lee, In-Jin Jang and Jae Yong Chung
      Drug Metabolism and Disposition July 2014, 42 (7) 1174-1179; DOI: https://doi.org/10.1124/dmd.113.055616

Z

  1. Zeng, Su

    1. You have access
      The Contribution of Human OCT1, OCT3, and CYP3A4 to Nitidine Chloride–Induced Hepatocellular Toxicity
      Liping Li, Meijuan Tu, Xi Yang, Siyuan Sun, Xiaodan Wu, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition July 2014, 42 (7) 1227-1234; DOI: https://doi.org/10.1124/dmd.113.056689
  2. Zhou, Hui

    1. You have access
      The Contribution of Human OCT1, OCT3, and CYP3A4 to Nitidine Chloride–Induced Hepatocellular Toxicity
      Liping Li, Meijuan Tu, Xi Yang, Siyuan Sun, Xiaodan Wu, Hui Zhou, Su Zeng and Huidi Jiang
      Drug Metabolism and Disposition July 2014, 42 (7) 1227-1234; DOI: https://doi.org/10.1124/dmd.113.056689
  3. Zientek, Michael A.

    1. You have access
      Relative Contributions of Cytochrome CYP3A4 Versus CYP3A5 for CYP3A-Cleared Drugs Assessed In Vitro Using a CYP3A4-Selective Inactivator (CYP3cide)
      Elaine Tseng, Robert L. Walsky, Ricardo A. Luzietti, Jennifer J. Harris, Rachel E. Kosa, Theunis C. Goosen, Michael A. Zientek and R. Scott Obach
      Drug Metabolism and Disposition July 2014, 42 (7) 1163-1173; DOI: https://doi.org/10.1124/dmd.114.057000
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Drug Metabolism and Disposition: 42 (7)
Drug Metabolism and Disposition
Vol. 42, Issue 7
1 Jul 2014
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  • Pharmacokinetics and Disposition of Biologics
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