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Research ArticleArticle

Glucuronidation of Drugs and Drug-Induced Toxicity in Humanized UDP-Glucuronosyltransferase 1 Mice

Yuki Kutsuno, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
Drug Metabolism and Disposition July 2014, 42 (7) 1146-1152; DOI: https://doi.org/10.1124/dmd.114.057083
Yuki Kutsuno
School of Pharmacy, Kitasato University, Tokyo, Japan (Y.K., T.I., R.F.); and Laboratory of Environmental Toxicology, Department of Pharmacology, University of California San Diego, La Jolla, California (R.H.T.)
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Tomoo Itoh
School of Pharmacy, Kitasato University, Tokyo, Japan (Y.K., T.I., R.F.); and Laboratory of Environmental Toxicology, Department of Pharmacology, University of California San Diego, La Jolla, California (R.H.T.)
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Robert H. Tukey
School of Pharmacy, Kitasato University, Tokyo, Japan (Y.K., T.I., R.F.); and Laboratory of Environmental Toxicology, Department of Pharmacology, University of California San Diego, La Jolla, California (R.H.T.)
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Ryoichi Fujiwara
School of Pharmacy, Kitasato University, Tokyo, Japan (Y.K., T.I., R.F.); and Laboratory of Environmental Toxicology, Department of Pharmacology, University of California San Diego, La Jolla, California (R.H.T.)
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Article Information

vol. 42 no. 7 1146-1152
DOI 
https://doi.org/10.1124/dmd.114.057083
PubMed 
24764149

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received January 15, 2014
  • Accepted April 24, 2014
  • Published online May 23, 2014.

Article Versions

  • Earlier version (April 24, 2014 - 07:27).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yuki Kutsuno,
  2. Tomoo Itoh,
  3. Robert H. Tukey, and
  4. Ryoichi Fujiwara
  1. School of Pharmacy, Kitasato University, Tokyo, Japan (Y.K., T.I., R.F.); and Laboratory of Environmental Toxicology, Department of Pharmacology, University of California San Diego, La Jolla, California (R.H.T.)
  1. Address correspondence to:
    Dr. Ryoichi Fujiwara, School of Pharmacy, Kitasato University, 5-9-1 Shirokane, Minato-ku, Tokyo 108-8641, Japan. E-mail: fujiwarar{at}pharm.kitasato-u.ac.jp
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Drug Metabolism and Disposition: 42 (7)
Drug Metabolism and Disposition
Vol. 42, Issue 7
1 Jul 2014
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Research ArticleArticle

Glucuronidation and Drug-Induced Toxicity in Humanized UGT1 Mice

Yuki Kutsuno, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
Drug Metabolism and Disposition July 1, 2014, 42 (7) 1146-1152; DOI: https://doi.org/10.1124/dmd.114.057083

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Research ArticleArticle

Glucuronidation and Drug-Induced Toxicity in Humanized UGT1 Mice

Yuki Kutsuno, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
Drug Metabolism and Disposition July 1, 2014, 42 (7) 1146-1152; DOI: https://doi.org/10.1124/dmd.114.057083
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