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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
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Index by author

August 01, 2014; Volume 42,Issue 8
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Achour, Brahim

    1. You have access
      Expression of Hepatic Drug-Metabolizing Cytochrome P450 Enzymes and Their Intercorrelations: A Meta-Analysis
      Brahim Achour, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition August 2014, 42 (8) 1349-1356; DOI: https://doi.org/10.1124/dmd.114.058834
  2. Atchley, William T.

    1. You have access
      Treatment with a Monoclonal Antibody against Methamphetamine and Amphetamine Reduces Maternal and Fetal Rat Brain Concentrations in Late Pregnancy
      Sarah J. White, Howard P. Hendrickson, William T. Atchley, Elizabeth M. Laurenzana, W. Brooks Gentry, D. Keith Williams and S. Michael Owens
      Drug Metabolism and Disposition August 2014, 42 (8) 1285-1291; DOI: https://doi.org/10.1124/dmd.114.056879

B

  1. Bae, Jong-Sup

    1. You have access
      Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide Including CYP3A4-Mediated C-Demethylation in Human Liver Microsomes with High-Resolution/High-Accuracy Tandem Mass
      Min Song, Doohyun Lee, Sun Kim, Jong-Sup Bae, Jaeick Lee, Young-Dae Gong, Taeho Lee and Sangkyu Lee
      Drug Metabolism and Disposition August 2014, 42 (8) 1252-1260; DOI: https://doi.org/10.1124/dmd.114.057570
  2. Barber, Jill

    1. You have access
      Expression of Hepatic Drug-Metabolizing Cytochrome P450 Enzymes and Their Intercorrelations: A Meta-Analysis
      Brahim Achour, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition August 2014, 42 (8) 1349-1356; DOI: https://doi.org/10.1124/dmd.114.058834
  3. Barnaba, Carlo

    1. You have access
      In Vitro Oxidative Metabolism of 6-Mercaptopurine in Human Liver: Insights into the Role of the Molybdoflavoenzymes Aldehyde Oxidase, Xanthine Oxidase, and Xanthine Dehydrogenase
      Kanika V. Choughule, Carlo Barnaba, Carolyn A. Joswig-Jones and Jeffrey P. Jones
      Drug Metabolism and Disposition August 2014, 42 (8) 1334-1340; DOI: https://doi.org/10.1124/dmd.114.058107
  4. Bartizal, Kenneth

    1. You have access
      Absorption, Distribution, Metabolism, and Excretion of the Novel Antibacterial Prodrug Tedizolid Phosphate
      Voon Ong, Shawn Flanagan, Edward Fang, Howard J. Dreskin, Jeffrey B. Locke, Kenneth Bartizal and Philippe Prokocimer
      Drug Metabolism and Disposition August 2014, 42 (8) 1275-1284; DOI: https://doi.org/10.1124/dmd.113.056697
  5. Bowen, Chester

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
  6. Bruyère, Arnaud

    1. You have access
      Interactions of Endosulfan and Methoxychlor Involving CYP3A4 and CYP2B6 in Human HepaRG Cells
      Camille C. Savary, Rozenn Jossé, Arnaud Bruyère, Fabrice Guillet, Marie-Anne Robin and André Guillouzo
      Drug Metabolism and Disposition August 2014, 42 (8) 1235-1240; DOI: https://doi.org/10.1124/dmd.114.057786

C

  1. Chen, Liangfu

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
    2. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
  2. Choughule, Kanika V.

    1. You have access
      In Vitro Oxidative Metabolism of 6-Mercaptopurine in Human Liver: Insights into the Role of the Molybdoflavoenzymes Aldehyde Oxidase, Xanthine Oxidase, and Xanthine Dehydrogenase
      Kanika V. Choughule, Carlo Barnaba, Carolyn A. Joswig-Jones and Jeffrey P. Jones
      Drug Metabolism and Disposition August 2014, 42 (8) 1334-1340; DOI: https://doi.org/10.1124/dmd.114.058107
  3. Chu, Xiaoyan

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976

D

  1. Dai, Renke

    1. You have access
      Different Binding Sites of Bovine Organic Anion–Transporting Polypeptide1a2 Are Involved in the Transport of Different Fluoroquinolones
      Yunpeng Xiao, Jifeng Deng, Xiaoxiao Liu, Jiujiu Huang, Yongxue Sun, Renke Dai and Mei Hong
      Drug Metabolism and Disposition August 2014, 42 (8) 1261-1267; DOI: https://doi.org/10.1124/dmd.114.057448
  2. Dallas, Shannon

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  3. de Koning, Barbara A. E.

    1. You have access
      Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
      Miriam G. Mooij, Ute I. Schwarz, Barbara A. E. de Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, Johannes B. van Goudoever, Dick Tibboel, Richard B. Kim and Saskia N. de Wildt
      Drug Metabolism and Disposition August 2014, 42 (8) 1268-1274; DOI: https://doi.org/10.1124/dmd.114.056929
  4. Deng, Jifeng

    1. You have access
      Different Binding Sites of Bovine Organic Anion–Transporting Polypeptide1a2 Are Involved in the Transport of Different Fluoroquinolones
      Yunpeng Xiao, Jifeng Deng, Xiaoxiao Liu, Jiujiu Huang, Yongxue Sun, Renke Dai and Mei Hong
      Drug Metabolism and Disposition August 2014, 42 (8) 1261-1267; DOI: https://doi.org/10.1124/dmd.114.057448
  5. Deng, Yanli

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
  6. de Wildt, Saskia N.

    1. You have access
      Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
      Miriam G. Mooij, Ute I. Schwarz, Barbara A. E. de Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, Johannes B. van Goudoever, Dick Tibboel, Richard B. Kim and Saskia N. de Wildt
      Drug Metabolism and Disposition August 2014, 42 (8) 1268-1274; DOI: https://doi.org/10.1124/dmd.114.056929
  7. Ding, Xinxin

    1. You have access
      Generation and Characterization of a Novel CYP2A13-Transgenic Mouse Model
      Kunzhi Jia, Lei Li, Zhihua Liu, Matthew Hartog, Kerri Kluetzman, Qing-Yu Zhang and Xinxin Ding
      Drug Metabolism and Disposition August 2014, 42 (8) 1341-1348; DOI: https://doi.org/10.1124/dmd.114.059188
  8. Dreskin, Howard J.

    1. You have access
      Absorption, Distribution, Metabolism, and Excretion of the Novel Antibacterial Prodrug Tedizolid Phosphate
      Voon Ong, Shawn Flanagan, Edward Fang, Howard J. Dreskin, Jeffrey B. Locke, Kenneth Bartizal and Philippe Prokocimer
      Drug Metabolism and Disposition August 2014, 42 (8) 1275-1284; DOI: https://doi.org/10.1124/dmd.113.056697
  9. Dumont, Etienne

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420

E

  1. Elmquist, William F.

    1. You have access
      Factors Influencing the CNS Distribution of a Novel MEK-1/2 Inhibitor: Implications for Combination Therapy for Melanoma Brain Metastases
      Shruthi Vaidhyanathan, Rajendar K. Mittapalli, Jann N. Sarkaria and William F. Elmquist
      Drug Metabolism and Disposition August 2014, 42 (8) 1292-1300; DOI: https://doi.org/10.1124/dmd.114.058339
  2. Evers, Raymond

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976

F

  1. Fang, Edward

    1. You have access
      Absorption, Distribution, Metabolism, and Excretion of the Novel Antibacterial Prodrug Tedizolid Phosphate
      Voon Ong, Shawn Flanagan, Edward Fang, Howard J. Dreskin, Jeffrey B. Locke, Kenneth Bartizal and Philippe Prokocimer
      Drug Metabolism and Disposition August 2014, 42 (8) 1275-1284; DOI: https://doi.org/10.1124/dmd.113.056697
  2. Felgate, Clive

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
  3. Flanagan, Shawn

    1. You have access
      Absorption, Distribution, Metabolism, and Excretion of the Novel Antibacterial Prodrug Tedizolid Phosphate
      Voon Ong, Shawn Flanagan, Edward Fang, Howard J. Dreskin, Jeffrey B. Locke, Kenneth Bartizal and Philippe Prokocimer
      Drug Metabolism and Disposition August 2014, 42 (8) 1275-1284; DOI: https://doi.org/10.1124/dmd.113.056697
  4. Fukuda, Katsuyuki

    1. You have access
      Oxidative Metabolic Pathway of Lenvatinib Mediated by Aldehyde Oxidase
      Kazuko Inoue, Hitoshi Mizuo, Shinki Kawaguchi, Katsuyuki Fukuda, Kazutomi Kusano and Tsutomu Yoshimura
      Drug Metabolism and Disposition August 2014, 42 (8) 1326-1333; DOI: https://doi.org/10.1124/dmd.114.058073

G

  1. Gaedigk, Roger

    1. You have access
      Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
      Miriam G. Mooij, Ute I. Schwarz, Barbara A. E. de Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, Johannes B. van Goudoever, Dick Tibboel, Richard B. Kim and Saskia N. de Wildt
      Drug Metabolism and Disposition August 2014, 42 (8) 1268-1274; DOI: https://doi.org/10.1124/dmd.114.056929
  2. Geier, Ethan G.

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  3. Gentry, W. Brooks

    1. You have access
      Treatment with a Monoclonal Antibody against Methamphetamine and Amphetamine Reduces Maternal and Fetal Rat Brain Concentrations in Late Pregnancy
      Sarah J. White, Howard P. Hendrickson, William T. Atchley, Elizabeth M. Laurenzana, W. Brooks Gentry, D. Keith Williams and S. Michael Owens
      Drug Metabolism and Disposition August 2014, 42 (8) 1285-1291; DOI: https://doi.org/10.1124/dmd.114.056879
  4. Gong, Young-Dae

    1. You have access
      Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide Including CYP3A4-Mediated C-Demethylation in Human Liver Microsomes with High-Resolution/High-Accuracy Tandem Mass
      Min Song, Doohyun Lee, Sun Kim, Jong-Sup Bae, Jaeick Lee, Young-Dae Gong, Taeho Lee and Sangkyu Lee
      Drug Metabolism and Disposition August 2014, 42 (8) 1252-1260; DOI: https://doi.org/10.1124/dmd.114.057570
  5. Gorycki, Peter D.

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
  6. Guillet, Fabrice

    1. You have access
      Interactions of Endosulfan and Methoxychlor Involving CYP3A4 and CYP2B6 in Human HepaRG Cells
      Camille C. Savary, Rozenn Jossé, Arnaud Bruyère, Fabrice Guillet, Marie-Anne Robin and André Guillouzo
      Drug Metabolism and Disposition August 2014, 42 (8) 1235-1240; DOI: https://doi.org/10.1124/dmd.114.057786
  7. Guillouzo, André

    1. You have access
      Interactions of Endosulfan and Methoxychlor Involving CYP3A4 and CYP2B6 in Human HepaRG Cells
      Camille C. Savary, Rozenn Jossé, Arnaud Bruyère, Fabrice Guillet, Marie-Anne Robin and André Guillouzo
      Drug Metabolism and Disposition August 2014, 42 (8) 1235-1240; DOI: https://doi.org/10.1124/dmd.114.057786

H

  1. Hartog, Matthew

    1. You have access
      Generation and Characterization of a Novel CYP2A13-Transgenic Mouse Model
      Kunzhi Jia, Lei Li, Zhihua Liu, Matthew Hartog, Kerri Kluetzman, Qing-Yu Zhang and Xinxin Ding
      Drug Metabolism and Disposition August 2014, 42 (8) 1341-1348; DOI: https://doi.org/10.1124/dmd.114.059188
  2. Hendrickson, Howard P.

    1. You have access
      Treatment with a Monoclonal Antibody against Methamphetamine and Amphetamine Reduces Maternal and Fetal Rat Brain Concentrations in Late Pregnancy
      Sarah J. White, Howard P. Hendrickson, William T. Atchley, Elizabeth M. Laurenzana, W. Brooks Gentry, D. Keith Williams and S. Michael Owens
      Drug Metabolism and Disposition August 2014, 42 (8) 1285-1291; DOI: https://doi.org/10.1124/dmd.114.056879
  3. Hong, Mei

    1. You have access
      Different Binding Sites of Bovine Organic Anion–Transporting Polypeptide1a2 Are Involved in the Transport of Different Fluoroquinolones
      Yunpeng Xiao, Jifeng Deng, Xiaoxiao Liu, Jiujiu Huang, Yongxue Sun, Renke Dai and Mei Hong
      Drug Metabolism and Disposition August 2014, 42 (8) 1261-1267; DOI: https://doi.org/10.1124/dmd.114.057448
  4. Huang, Jiujiu

    1. You have access
      Different Binding Sites of Bovine Organic Anion–Transporting Polypeptide1a2 Are Involved in the Transport of Different Fluoroquinolones
      Yunpeng Xiao, Jifeng Deng, Xiaoxiao Liu, Jiujiu Huang, Yongxue Sun, Renke Dai and Mei Hong
      Drug Metabolism and Disposition August 2014, 42 (8) 1261-1267; DOI: https://doi.org/10.1124/dmd.114.057448

I

  1. Inoue, Kazuko

    1. You have access
      Oxidative Metabolic Pathway of Lenvatinib Mediated by Aldehyde Oxidase
      Kazuko Inoue, Hitoshi Mizuo, Shinki Kawaguchi, Katsuyuki Fukuda, Kazutomi Kusano and Tsutomu Yoshimura
      Drug Metabolism and Disposition August 2014, 42 (8) 1326-1333; DOI: https://doi.org/10.1124/dmd.114.058073

J

  1. Jia, Kunzhi

    1. You have access
      Generation and Characterization of a Novel CYP2A13-Transgenic Mouse Model
      Kunzhi Jia, Lei Li, Zhihua Liu, Matthew Hartog, Kerri Kluetzman, Qing-Yu Zhang and Xinxin Ding
      Drug Metabolism and Disposition August 2014, 42 (8) 1341-1348; DOI: https://doi.org/10.1124/dmd.114.059188
  2. Jones, Jeffrey P.

    1. You have access
      In Vitro Oxidative Metabolism of 6-Mercaptopurine in Human Liver: Insights into the Role of the Molybdoflavoenzymes Aldehyde Oxidase, Xanthine Oxidase, and Xanthine Dehydrogenase
      Kanika V. Choughule, Carlo Barnaba, Carolyn A. Joswig-Jones and Jeffrey P. Jones
      Drug Metabolism and Disposition August 2014, 42 (8) 1334-1340; DOI: https://doi.org/10.1124/dmd.114.058107
  3. Jones, Lori

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
  4. Jossé, Rozenn

    1. You have access
      Interactions of Endosulfan and Methoxychlor Involving CYP3A4 and CYP2B6 in Human HepaRG Cells
      Camille C. Savary, Rozenn Jossé, Arnaud Bruyère, Fabrice Guillet, Marie-Anne Robin and André Guillouzo
      Drug Metabolism and Disposition August 2014, 42 (8) 1235-1240; DOI: https://doi.org/10.1124/dmd.114.057786
  5. Joswig-Jones, Carolyn A.

    1. You have access
      In Vitro Oxidative Metabolism of 6-Mercaptopurine in Human Liver: Insights into the Role of the Molybdoflavoenzymes Aldehyde Oxidase, Xanthine Oxidase, and Xanthine Dehydrogenase
      Kanika V. Choughule, Carlo Barnaba, Carolyn A. Joswig-Jones and Jeffrey P. Jones
      Drug Metabolism and Disposition August 2014, 42 (8) 1334-1340; DOI: https://doi.org/10.1124/dmd.114.058107

K

  1. Kawaguchi, Shinki

    1. You have access
      Oxidative Metabolic Pathway of Lenvatinib Mediated by Aldehyde Oxidase
      Kazuko Inoue, Hitoshi Mizuo, Shinki Kawaguchi, Katsuyuki Fukuda, Kazutomi Kusano and Tsutomu Yoshimura
      Drug Metabolism and Disposition August 2014, 42 (8) 1326-1333; DOI: https://doi.org/10.1124/dmd.114.058073
  2. Kehler, Jonathan

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  3. Kim, Richard B.

    1. You have access
      Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
      Miriam G. Mooij, Ute I. Schwarz, Barbara A. E. de Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, Johannes B. van Goudoever, Dick Tibboel, Richard B. Kim and Saskia N. de Wildt
      Drug Metabolism and Disposition August 2014, 42 (8) 1268-1274; DOI: https://doi.org/10.1124/dmd.114.056929
  4. Kim, Sun

    1. You have access
      Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide Including CYP3A4-Mediated C-Demethylation in Human Liver Microsomes with High-Resolution/High-Accuracy Tandem Mass
      Min Song, Doohyun Lee, Sun Kim, Jong-Sup Bae, Jaeick Lee, Young-Dae Gong, Taeho Lee and Sangkyu Lee
      Drug Metabolism and Disposition August 2014, 42 (8) 1252-1260; DOI: https://doi.org/10.1124/dmd.114.057570
  5. Kluetzman, Kerri

    1. You have access
      Generation and Characterization of a Novel CYP2A13-Transgenic Mouse Model
      Kunzhi Jia, Lei Li, Zhihua Liu, Matthew Hartog, Kerri Kluetzman, Qing-Yu Zhang and Xinxin Ding
      Drug Metabolism and Disposition August 2014, 42 (8) 1341-1348; DOI: https://doi.org/10.1124/dmd.114.059188
  6. Kunta, Jeevan

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  7. Kusano, Kazutomi

    1. You have access
      Oxidative Metabolic Pathway of Lenvatinib Mediated by Aldehyde Oxidase
      Kazuko Inoue, Hitoshi Mizuo, Shinki Kawaguchi, Katsuyuki Fukuda, Kazutomi Kusano and Tsutomu Yoshimura
      Drug Metabolism and Disposition August 2014, 42 (8) 1326-1333; DOI: https://doi.org/10.1124/dmd.114.058073

L

  1. Laplanche, Loic

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  2. Laurenzana, Elizabeth M.

    1. You have access
      Treatment with a Monoclonal Antibody against Methamphetamine and Amphetamine Reduces Maternal and Fetal Rat Brain Concentrations in Late Pregnancy
      Sarah J. White, Howard P. Hendrickson, William T. Atchley, Elizabeth M. Laurenzana, W. Brooks Gentry, D. Keith Williams and S. Michael Owens
      Drug Metabolism and Disposition August 2014, 42 (8) 1285-1291; DOI: https://doi.org/10.1124/dmd.114.056879
  3. Lee, Doohyun

    1. You have access
      Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide Including CYP3A4-Mediated C-Demethylation in Human Liver Microsomes with High-Resolution/High-Accuracy Tandem Mass
      Min Song, Doohyun Lee, Sun Kim, Jong-Sup Bae, Jaeick Lee, Young-Dae Gong, Taeho Lee and Sangkyu Lee
      Drug Metabolism and Disposition August 2014, 42 (8) 1252-1260; DOI: https://doi.org/10.1124/dmd.114.057570
  4. Lee, Jaeick

    1. You have access
      Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide Including CYP3A4-Mediated C-Demethylation in Human Liver Microsomes with High-Resolution/High-Accuracy Tandem Mass
      Min Song, Doohyun Lee, Sun Kim, Jong-Sup Bae, Jaeick Lee, Young-Dae Gong, Taeho Lee and Sangkyu Lee
      Drug Metabolism and Disposition August 2014, 42 (8) 1252-1260; DOI: https://doi.org/10.1124/dmd.114.057570
  5. Lee, Sangkyu

    1. You have access
      Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide Including CYP3A4-Mediated C-Demethylation in Human Liver Microsomes with High-Resolution/High-Accuracy Tandem Mass
      Min Song, Doohyun Lee, Sun Kim, Jong-Sup Bae, Jaeick Lee, Young-Dae Gong, Taeho Lee and Sangkyu Lee
      Drug Metabolism and Disposition August 2014, 42 (8) 1252-1260; DOI: https://doi.org/10.1124/dmd.114.057570
  6. Lee, Taeho

    1. You have access
      Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide Including CYP3A4-Mediated C-Demethylation in Human Liver Microsomes with High-Resolution/High-Accuracy Tandem Mass
      Min Song, Doohyun Lee, Sun Kim, Jong-Sup Bae, Jaeick Lee, Young-Dae Gong, Taeho Lee and Sangkyu Lee
      Drug Metabolism and Disposition August 2014, 42 (8) 1252-1260; DOI: https://doi.org/10.1124/dmd.114.057570
  7. Leeder, J. Steven

    1. You have access
      Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
      Miriam G. Mooij, Ute I. Schwarz, Barbara A. E. de Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, Johannes B. van Goudoever, Dick Tibboel, Richard B. Kim and Saskia N. de Wildt
      Drug Metabolism and Disposition August 2014, 42 (8) 1268-1274; DOI: https://doi.org/10.1124/dmd.114.056929
  8. Li, Lei

    1. You have access
      Generation and Characterization of a Novel CYP2A13-Transgenic Mouse Model
      Kunzhi Jia, Lei Li, Zhihua Liu, Matthew Hartog, Kerri Kluetzman, Qing-Yu Zhang and Xinxin Ding
      Drug Metabolism and Disposition August 2014, 42 (8) 1341-1348; DOI: https://doi.org/10.1124/dmd.114.059188
  9. Lin, Min

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
  10. Liu, Xiaoxiao

    1. You have access
      Different Binding Sites of Bovine Organic Anion–Transporting Polypeptide1a2 Are Involved in the Transport of Different Fluoroquinolones
      Yunpeng Xiao, Jifeng Deng, Xiaoxiao Liu, Jiujiu Huang, Yongxue Sun, Renke Dai and Mei Hong
      Drug Metabolism and Disposition August 2014, 42 (8) 1261-1267; DOI: https://doi.org/10.1124/dmd.114.057448
  11. Liu, Zhihua

    1. You have access
      Generation and Characterization of a Novel CYP2A13-Transgenic Mouse Model
      Kunzhi Jia, Lei Li, Zhihua Liu, Matthew Hartog, Kerri Kluetzman, Qing-Yu Zhang and Xinxin Ding
      Drug Metabolism and Disposition August 2014, 42 (8) 1341-1348; DOI: https://doi.org/10.1124/dmd.114.059188
  12. Locke, Jeffrey B.

    1. You have access
      Absorption, Distribution, Metabolism, and Excretion of the Novel Antibacterial Prodrug Tedizolid Phosphate
      Voon Ong, Shawn Flanagan, Edward Fang, Howard J. Dreskin, Jeffrey B. Locke, Kenneth Bartizal and Philippe Prokocimer
      Drug Metabolism and Disposition August 2014, 42 (8) 1275-1284; DOI: https://doi.org/10.1124/dmd.113.056697

M

  1. Mamaril-Fishman, Donna

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
    2. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
  2. Mezler, Mario

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  3. Michaels, Scott

    1. You have access
      The Revised Human Liver Cytochrome P450 “Pie”: Absolute Protein Quantification of CYP4F and CYP3A Enzymes Using Targeted Quantitative Proteomics
      Scott Michaels and Michael Zhuo Wang
      Drug Metabolism and Disposition August 2014, 42 (8) 1241-1251; DOI: https://doi.org/10.1124/dmd.114.058040
  4. Mittapalli, Rajendar K.

    1. You have access
      Factors Influencing the CNS Distribution of a Novel MEK-1/2 Inhibitor: Implications for Combination Therapy for Melanoma Brain Metastases
      Shruthi Vaidhyanathan, Rajendar K. Mittapalli, Jann N. Sarkaria and William F. Elmquist
      Drug Metabolism and Disposition August 2014, 42 (8) 1292-1300; DOI: https://doi.org/10.1124/dmd.114.058339
  5. Mizuo, Hitoshi

    1. You have access
      Oxidative Metabolic Pathway of Lenvatinib Mediated by Aldehyde Oxidase
      Kazuko Inoue, Hitoshi Mizuo, Shinki Kawaguchi, Katsuyuki Fukuda, Kazutomi Kusano and Tsutomu Yoshimura
      Drug Metabolism and Disposition August 2014, 42 (8) 1326-1333; DOI: https://doi.org/10.1124/dmd.114.058073
  6. Mooij, Miriam G.

    1. You have access
      Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
      Miriam G. Mooij, Ute I. Schwarz, Barbara A. E. de Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, Johannes B. van Goudoever, Dick Tibboel, Richard B. Kim and Saskia N. de Wildt
      Drug Metabolism and Disposition August 2014, 42 (8) 1268-1274; DOI: https://doi.org/10.1124/dmd.114.056929

N

  1. Naderer, Odin

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420

O

  1. Ong, Voon

    1. You have access
      Absorption, Distribution, Metabolism, and Excretion of the Novel Antibacterial Prodrug Tedizolid Phosphate
      Voon Ong, Shawn Flanagan, Edward Fang, Howard J. Dreskin, Jeffrey B. Locke, Kenneth Bartizal and Philippe Prokocimer
      Drug Metabolism and Disposition August 2014, 42 (8) 1275-1284; DOI: https://doi.org/10.1124/dmd.113.056697
  2. Owens, S. Michael

    1. You have access
      Treatment with a Monoclonal Antibody against Methamphetamine and Amphetamine Reduces Maternal and Fetal Rat Brain Concentrations in Late Pregnancy
      Sarah J. White, Howard P. Hendrickson, William T. Atchley, Elizabeth M. Laurenzana, W. Brooks Gentry, D. Keith Williams and S. Michael Owens
      Drug Metabolism and Disposition August 2014, 42 (8) 1285-1291; DOI: https://doi.org/10.1124/dmd.114.056879

P

  1. Pang, Jodie

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  2. Patel, Parul

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
  3. Pierre, Esaie

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
  4. Prasad, Bhagwat

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  5. Prokocimer, Philippe

    1. You have access
      Absorption, Distribution, Metabolism, and Excretion of the Novel Antibacterial Prodrug Tedizolid Phosphate
      Voon Ong, Shawn Flanagan, Edward Fang, Howard J. Dreskin, Jeffrey B. Locke, Kenneth Bartizal and Philippe Prokocimer
      Drug Metabolism and Disposition August 2014, 42 (8) 1275-1284; DOI: https://doi.org/10.1124/dmd.113.056697

R

  1. Robin, Marie-Anne

    1. You have access
      Interactions of Endosulfan and Methoxychlor Involving CYP3A4 and CYP2B6 in Human HepaRG Cells
      Camille C. Savary, Rozenn Jossé, Arnaud Bruyère, Fabrice Guillet, Marie-Anne Robin and André Guillouzo
      Drug Metabolism and Disposition August 2014, 42 (8) 1235-1240; DOI: https://doi.org/10.1124/dmd.114.057786
  2. Rode, Anja

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  3. Rostami-Hodjegan, Amin

    1. You have access
      Expression of Hepatic Drug-Metabolizing Cytochrome P450 Enzymes and Their Intercorrelations: A Meta-Analysis
      Brahim Achour, Jill Barber and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition August 2014, 42 (8) 1349-1356; DOI: https://doi.org/10.1124/dmd.114.058834

S

  1. Salphati, Laurent

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  2. Samsom, Janneke N.

    1. You have access
      Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
      Miriam G. Mooij, Ute I. Schwarz, Barbara A. E. de Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, Johannes B. van Goudoever, Dick Tibboel, Richard B. Kim and Saskia N. de Wildt
      Drug Metabolism and Disposition August 2014, 42 (8) 1268-1274; DOI: https://doi.org/10.1124/dmd.114.056929
  3. Sarkaria, Jann N.

    1. You have access
      Factors Influencing the CNS Distribution of a Novel MEK-1/2 Inhibitor: Implications for Combination Therapy for Melanoma Brain Metastases
      Shruthi Vaidhyanathan, Rajendar K. Mittapalli, Jann N. Sarkaria and William F. Elmquist
      Drug Metabolism and Disposition August 2014, 42 (8) 1292-1300; DOI: https://doi.org/10.1124/dmd.114.058339
  4. Savary, Camille C.

    1. You have access
      Interactions of Endosulfan and Methoxychlor Involving CYP3A4 and CYP2B6 in Human HepaRG Cells
      Camille C. Savary, Rozenn Jossé, Arnaud Bruyère, Fabrice Guillet, Marie-Anne Robin and André Guillouzo
      Drug Metabolism and Disposition August 2014, 42 (8) 1235-1240; DOI: https://doi.org/10.1124/dmd.114.057786
  5. Scheer, Nico

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  6. Schinkel, Alfred H.

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  7. Schwarz, Ute I.

    1. You have access
      Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
      Miriam G. Mooij, Ute I. Schwarz, Barbara A. E. de Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, Johannes B. van Goudoever, Dick Tibboel, Richard B. Kim and Saskia N. de Wildt
      Drug Metabolism and Disposition August 2014, 42 (8) 1268-1274; DOI: https://doi.org/10.1124/dmd.114.056929
  8. Soars, Matthew G.

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  9. Song, Min

    1. You have access
      Identification of Metabolites of N-(5-Benzoyl-2-(4-(2-Methoxyphenyl)piperazin-1-yl)thiazol-4-yl)pivalamide Including CYP3A4-Mediated C-Demethylation in Human Liver Microsomes with High-Resolution/High-Accuracy Tandem Mass
      Min Song, Doohyun Lee, Sun Kim, Jong-Sup Bae, Jaeick Lee, Young-Dae Gong, Taeho Lee and Sangkyu Lee
      Drug Metabolism and Disposition August 2014, 42 (8) 1252-1260; DOI: https://doi.org/10.1124/dmd.114.057570
  10. Spaans, Edwin

    1. You have access
      Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
      Miriam G. Mooij, Ute I. Schwarz, Barbara A. E. de Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, Johannes B. van Goudoever, Dick Tibboel, Richard B. Kim and Saskia N. de Wildt
      Drug Metabolism and Disposition August 2014, 42 (8) 1268-1274; DOI: https://doi.org/10.1124/dmd.114.056929
  11. Stump, Patrick

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
  12. Sun, Yongxue

    1. You have access
      Different Binding Sites of Bovine Organic Anion–Transporting Polypeptide1a2 Are Involved in the Transport of Different Fluoroquinolones
      Yunpeng Xiao, Jifeng Deng, Xiaoxiao Liu, Jiujiu Huang, Yongxue Sun, Renke Dai and Mei Hong
      Drug Metabolism and Disposition August 2014, 42 (8) 1261-1267; DOI: https://doi.org/10.1124/dmd.114.057448

T

  1. Tibboel, Dick

    1. You have access
      Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
      Miriam G. Mooij, Ute I. Schwarz, Barbara A. E. de Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, Johannes B. van Goudoever, Dick Tibboel, Richard B. Kim and Saskia N. de Wildt
      Drug Metabolism and Disposition August 2014, 42 (8) 1268-1274; DOI: https://doi.org/10.1124/dmd.114.056929

U

  1. Unadkat, Jashvant D.

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976

V

  1. Vaidhyanathan, Shruthi

    1. You have access
      Factors Influencing the CNS Distribution of a Novel MEK-1/2 Inhibitor: Implications for Combination Therapy for Melanoma Brain Metastases
      Shruthi Vaidhyanathan, Rajendar K. Mittapalli, Jann N. Sarkaria and William F. Elmquist
      Drug Metabolism and Disposition August 2014, 42 (8) 1292-1300; DOI: https://doi.org/10.1124/dmd.114.058339
  2. van Goudoever, Johannes B.

    1. You have access
      Ontogeny of Human Hepatic and Intestinal Transporter Gene Expression during Childhood: Age Matters
      Miriam G. Mooij, Ute I. Schwarz, Barbara A. E. de Koning, J. Steven Leeder, Roger Gaedigk, Janneke N. Samsom, Edwin Spaans, Johannes B. van Goudoever, Dick Tibboel, Richard B. Kim and Saskia N. de Wildt
      Drug Metabolism and Disposition August 2014, 42 (8) 1268-1274; DOI: https://doi.org/10.1124/dmd.114.056929
  3. van Waterschoot, Robert A. B.

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      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
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      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976

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      The Revised Human Liver Cytochrome P450 “Pie”: Absolute Protein Quantification of CYP4F and CYP3A Enzymes Using Targeted Quantitative Proteomics
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      Drug Metabolism and Disposition August 2014, 42 (8) 1241-1251; DOI: https://doi.org/10.1124/dmd.114.058040
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      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
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      Drug Metabolism and Disposition August 2014, 42 (8) 1285-1291; DOI: https://doi.org/10.1124/dmd.114.056879
  4. Williams, D. Keith

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      Treatment with a Monoclonal Antibody against Methamphetamine and Amphetamine Reduces Maternal and Fetal Rat Brain Concentrations in Late Pregnancy
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      Drug Metabolism and Disposition August 2014, 42 (8) 1285-1291; DOI: https://doi.org/10.1124/dmd.114.056879

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  1. Xiao, Yunpeng

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      Different Binding Sites of Bovine Organic Anion–Transporting Polypeptide1a2 Are Involved in the Transport of Different Fluoroquinolones
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      Drug Metabolism and Disposition August 2014, 42 (8) 1261-1267; DOI: https://doi.org/10.1124/dmd.114.057448

Y

  1. Yabut, Jocelyn

    1. You have access
      Evaluation of Organic Anion Transporting Polypeptide 1B1 and 1B3 Humanized Mice as a Translational Model to Study the Pharmacokinetics of Statins
      Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Raymond Evers, Donna Mamaril-Fishman, Ethan G. Geier, Jonathan Kehler, Jeevan Kunta, Mario Mezler, Loic Laplanche, Jodie Pang, Anja Rode, Matthew G. Soars, Jashvant D. Unadkat, Robert A. B. van Waterschoot, Jocelyn Yabut, Alfred H. Schinkel and Nico Scheer
      Drug Metabolism and Disposition August 2014, 42 (8) 1301-1313; DOI: https://doi.org/10.1124/dmd.114.057976
  2. Yoshimura, Tsutomu

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      Oxidative Metabolic Pathway of Lenvatinib Mediated by Aldehyde Oxidase
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      Drug Metabolism and Disposition August 2014, 42 (8) 1326-1333; DOI: https://doi.org/10.1124/dmd.114.058073

Z

  1. Zhang, Qing-Yu

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      Generation and Characterization of a Novel CYP2A13-Transgenic Mouse Model
      Kunzhi Jia, Lei Li, Zhihua Liu, Matthew Hartog, Kerri Kluetzman, Qing-Yu Zhang and Xinxin Ding
      Drug Metabolism and Disposition August 2014, 42 (8) 1341-1348; DOI: https://doi.org/10.1124/dmd.114.059188
  2. Zhu, John

    1. You have access
      Investigation of Metabolism and Disposition of GSK1322322, a Peptidase Deformylase Inhibitor, in Healthy Humans Using the Entero-Test for Biliary Sampling
      Donna Mamaril-Fishman, John Zhu, Min Lin, Clive Felgate, Lori Jones, Patrick Stump, Esaie Pierre, Chester Bowen, Odin Naderer, Etienne Dumont, Parul Patel, Peter D. Gorycki, Bo Wen, Liangfu Chen and Yanli Deng
      Drug Metabolism and Disposition August 2014, 42 (8) 1314-1325; DOI: https://doi.org/10.1124/dmd.114.058420
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Drug Metabolism and Disposition: 42 (8)
Drug Metabolism and Disposition
Vol. 42, Issue 8
1 Aug 2014
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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