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Research ArticleArticle

The Need for Human Breast Cancer Resistance Protein Substrate and Inhibition Evaluation in Drug Discovery and Development: Why, When, and How?

Agnès Poirier, Renée Portmann, Anne-Christine Cascais, Urs Bader, Isabelle Walter, Mohammed Ullah and Christoph Funk
Drug Metabolism and Disposition September 2014, 42 (9) 1466-1477; DOI: https://doi.org/10.1124/dmd.114.058248

Article Information

vol. 42 no. 9 1466-1477
DOI 
https://doi.org/10.1124/dmd.114.058248
PubMed 
24989889
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 19, 2014
  • Accepted July 2, 2014
  • Published online August 6, 2014.

Article Versions

Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Agnès Poirier,
  2. Renée Portmann,
  3. Anne-Christine Cascais,
  4. Urs Bader,
  5. Isabelle Walter,
  6. Mohammed Ullah, and
  7. Christoph Funk
  1. Roche Pharmaceutical Research and Early Development, Roche Innovation Center Basel, Basel, Switzerland
  1. Address correspondence to:
    Christoph Funk, F. Hoffmann-La Roche Ltd., B69/R154, Grenzacherstrasse 124, CH-4070 Basel, Switzerland. E-mail: christoph.funk{at}roche.com
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Agnès Poirier, Renée Portmann, Anne-Christine Cascais, Urs Bader, Isabelle Walter, Mohammed Ullah and Christoph Funk
Drug Metabolism and Disposition September 1, 2014, 42 (9) 1466-1477; DOI: https://doi.org/10.1124/dmd.114.058248
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