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Research ArticleArticle

Prediction of Organic Anion-Transporting Polypeptide 1B1- and 1B3-Mediated Hepatic Uptake of Statins Based on Transporter Protein Expression and Activity Data

Annett Kunze, Jörg Huwyler, Gian Camenisch and Birk Poller
Drug Metabolism and Disposition September 2014, 42 (9) 1514-1521; DOI: https://doi.org/10.1124/dmd.114.058412

Article Information

vol. 42 no. 9 1514-1521
DOI 
https://doi.org/10.1124/dmd.114.058412
PubMed 
24989890
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received April 4, 2014
  • Accepted July 2, 2014
  • Published online August 6, 2014.

Article Versions

Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Annett Kunze,
  2. Jörg Huwyler,
  3. Gian Camenisch, and
  4. Birk Poller
  1. Division of Drug Metabolism and Pharmacokinetics, Drug-Drug Interactions Section, Novartis Institutes for BioMedical Research, Basel, Switzerland (A.K., G.C., B.P.); and Department of Pharmaceutical Sciences, Division of Pharmaceutical Technology, University of Basel, Basel, Switzerland (A.K., J.H.)
  1. Address correspondence to:
    Dr. Birk Poller, Novartis Pharma AG, Fabrikstrasse 14, CH-4056 Basel, Switzerland. E-mail: birk.poller{at}novartis.com
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Research ArticleArticle

Prediction of OATP-Mediated Hepatic Uptake of Statins

Annett Kunze, Jörg Huwyler, Gian Camenisch and Birk Poller
Drug Metabolism and Disposition September 1, 2014, 42 (9) 1514-1521; DOI: https://doi.org/10.1124/dmd.114.058412
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