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Index by author

January 01, 2015; Volume 43,Issue 1

A

  1. Actis-Goretta, Lucas

    1. Modulation of (–)-Epicatechin Metabolism by Coadministration with Other Polyphenols in Caco-2 Cell Model
      Belén Sanchez-Bridge, Antoine Lévèques, Hequn Li, Emmanuelle Bertschy, Amaury Patin and Lucas Actis-Goretta
      Drug Metabolism and Disposition January 2015, 43 (1) 9-16; DOI: https://doi.org/10.1124/dmd.114.060590

  2. Akanuma, Shin-ichi

    1. Involvement of the H+/Organic Cation Antiporter in Nicotine Transport in Rat Liver
      Yuma Tega, Shin-ichi Akanuma, Yoshiyuki Kubo and Ken-ichi Hosoya
      Drug Metabolism and Disposition January 2015, 43 (1) 89-92; DOI: https://doi.org/10.1124/dmd.114.061002

  3. Alshogran, Osama Y.

    1. Effect of Experimental Kidney Disease on the Functional Expression of Hepatic Reductases
      Osama Y. Alshogran, Judith Naud, Andrew J. Ocque, François A. Leblond, Vincent Pichette and Thomas D. Nolin
      Drug Metabolism and Disposition January 2015, 43 (1) 100-106; DOI: https://doi.org/10.1124/dmd.114.061150

  4. Andersson, Linda

    1. HepaRG Cells as Human-Relevant In Vitro Model to Study the Effects of Inflammatory Stimuli on Cytochrome P450 Isoenzymes
      Katarina Rubin, Annika Janefeldt, Linda Andersson, Zsofia Berke, Ken Grime and Tommy B. Andersson
      Drug Metabolism and Disposition January 2015, 43 (1) 119-125; DOI: https://doi.org/10.1124/dmd.114.059246

  5. Andersson, Tommy B.

    1. HepaRG Cells as Human-Relevant In Vitro Model to Study the Effects of Inflammatory Stimuli on Cytochrome P450 Isoenzymes
      Katarina Rubin, Annika Janefeldt, Linda Andersson, Zsofia Berke, Ken Grime and Tommy B. Andersson
      Drug Metabolism and Disposition January 2015, 43 (1) 119-125; DOI: https://doi.org/10.1124/dmd.114.059246

  6. Annaert, Pieter

    1. Age-Dependent Activity of the Uptake Transporters Ntcp and Oatp1b2 in Male Rat Hepatocytes: From Birth Till Adulthood
      Sarinj Fattah, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition January 2015, 43 (1) 1-8; DOI: https://doi.org/10.1124/dmd.114.059212

  7. Ashton-Chess, Joanna

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  8. Augustijns, Patrick

    1. Age-Dependent Activity of the Uptake Transporters Ntcp and Oatp1b2 in Male Rat Hepatocytes: From Birth Till Adulthood
      Sarinj Fattah, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition January 2015, 43 (1) 1-8; DOI: https://doi.org/10.1124/dmd.114.059212

B

  1. Balavenkatraman, Kamal Kumar

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  2. Barr, John T.

    1. Inhibition of Human Aldehyde Oxidase Activity by Diet-Derived Constituents: Structural Influence, Enzyme-Ligand Interactions, and Clinical Relevance
      John T. Barr, Jeffrey P. Jones, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition January 2015, 43 (1) 34-41; DOI: https://doi.org/10.1124/dmd.114.061192

  3. Berke, Zsofia

    1. HepaRG Cells as Human-Relevant In Vitro Model to Study the Effects of Inflammatory Stimuli on Cytochrome P450 Isoenzymes
      Katarina Rubin, Annika Janefeldt, Linda Andersson, Zsofia Berke, Ken Grime and Tommy B. Andersson
      Drug Metabolism and Disposition January 2015, 43 (1) 119-125; DOI: https://doi.org/10.1124/dmd.114.059246

  4. Bertschi, Barbara

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  5. Bertschy, Emmanuelle

    1. Modulation of (–)-Epicatechin Metabolism by Coadministration with Other Polyphenols in Caco-2 Cell Model
      Belén Sanchez-Bridge, Antoine Lévèques, Hequn Li, Emmanuelle Bertschy, Amaury Patin and Lucas Actis-Goretta
      Drug Metabolism and Disposition January 2015, 43 (1) 9-16; DOI: https://doi.org/10.1124/dmd.114.060590

  6. Buckley, David B.

    1. Anti-CD28 Monoclonal Antibody–Stimulated Cytokines Released from Blood Suppress CYP1A2, CYP2B6, and CYP3A4 in Human Hepatocytes In VitroGraphic
      Maciej Czerwiński, Faraz Kazmi, Andrew Parkinson and David B. Buckley
      Drug Metabolism and Disposition January 2015, 43 (1) 42-52; DOI: https://doi.org/10.1124/dmd.114.060186

  7. Burczynski, Frank J.

    1. Assessing Steatotic Liver Function after Ischemia-Reperfusion Injury by In Vivo Multiphoton Imaging of Fluorescein Disposition
      Camilla A. Thorling, Lu Jin, Michael Weiss, Darrell Crawford, Xin Liu, Frank J. Burczynski, David Liu, Haolu Wang and Michael S. Roberts
      Drug Metabolism and Disposition January 2015, 43 (1) 154-162; DOI: https://doi.org/10.1124/dmd.114.060848

C

  1. Camenisch, Gian

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  2. Canet, Mark J.

    1. Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
      Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2015, 43 (1) 93-99; DOI: https://doi.org/10.1124/dmd.114.060103

  3. Cao, Jiaojiao

    1. Imperatorin Is a Mechanism-Based Inactivator of CYP2B6
      Liwei Zheng, Jiaojiao Cao, Dan Lu, Lin Ji, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition January 2015, 43 (1) 82-88; DOI: https://doi.org/10.1124/dmd.114.060558

  4. Cao, Yuan

    1. A Nonradioactive Approach to Investigate the Metabolism of Therapeutic Peptides by Tagging with 127I and Using Inductively-Coupled Plasma Mass Spectrometry Analysis
      Heng-Keang Lim, Yuan Cao, Xi Qiu, Jose Silva and David C. Evans
      Drug Metabolism and Disposition January 2015, 43 (1) 17-26; DOI: https://doi.org/10.1124/dmd.114.059774

  5. Chen, Chen

    1. The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism
      Jingjing Sheng, Xiaoting Tian, Guanglin Xu, Zhitao Wu, Chen Chen, Le Wang, Lili Pan, Chenggang Huang and Guoyu Pan
      Drug Metabolism and Disposition January 2015, 43 (1) 63-72; DOI: https://doi.org/10.1124/dmd.114.059923

  6. Cherrington, Nathan J.

    1. Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
      Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2015, 43 (1) 93-99; DOI: https://doi.org/10.1124/dmd.114.060103

  7. Crawford, Darrell

    1. Assessing Steatotic Liver Function after Ischemia-Reperfusion Injury by In Vivo Multiphoton Imaging of Fluorescein Disposition
      Camilla A. Thorling, Lu Jin, Michael Weiss, Darrell Crawford, Xin Liu, Frank J. Burczynski, David Liu, Haolu Wang and Michael S. Roberts
      Drug Metabolism and Disposition January 2015, 43 (1) 154-162; DOI: https://doi.org/10.1124/dmd.114.060848

  8. Czerwiński, Maciej

    1. Anti-CD28 Monoclonal Antibody–Stimulated Cytokines Released from Blood Suppress CYP1A2, CYP2B6, and CYP3A4 in Human Hepatocytes In VitroGraphic
      Maciej Czerwiński, Faraz Kazmi, Andrew Parkinson and David B. Buckley
      Drug Metabolism and Disposition January 2015, 43 (1) 42-52; DOI: https://doi.org/10.1124/dmd.114.060186

D

  1. Dave, Rutwij A.

    1. Quantitative Structure-Pharmacokinetic Relationships for the Prediction of Renal Clearance in Humans
      Rutwij A. Dave and Marilyn E. Morris
      Drug Metabolism and Disposition January 2015, 43 (1) 73-81; DOI: https://doi.org/10.1124/dmd.114.059857

E

  1. Evans, David C.

    1. A Nonradioactive Approach to Investigate the Metabolism of Therapeutic Peptides by Tagging with 127I and Using Inductively-Coupled Plasma Mass Spectrometry Analysis
      Heng-Keang Lim, Yuan Cao, Xi Qiu, Jose Silva and David C. Evans
      Drug Metabolism and Disposition January 2015, 43 (1) 17-26; DOI: https://doi.org/10.1124/dmd.114.059774

F

  1. Fattah, Sarinj

    1. Age-Dependent Activity of the Uptake Transporters Ntcp and Oatp1b2 in Male Rat Hepatocytes: From Birth Till Adulthood
      Sarinj Fattah, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition January 2015, 43 (1) 1-8; DOI: https://doi.org/10.1124/dmd.114.059212

  2. Finel, Moshe

    1. Dog UDP-Glucuronosyltransferase Enzymes of Subfamily 1A: Cloning, Expression, and Activity
      Johanna Troberg, Erkka Järvinen, Maria Muniz, Nina Sneitz, Johanna Mosorin, Marja Hagström and Moshe Finel
      Drug Metabolism and Disposition January 2015, 43 (1) 107-118; DOI: https://doi.org/10.1124/dmd.114.059303

  3. Forsberg, Markus M.

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

  4. Fujino, Hideki

    1. Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2015, 43 (1) 27-33; DOI: https://doi.org/10.1124/dmd.114.061275

G

  1. Grime, Ken

    1. HepaRG Cells as Human-Relevant In Vitro Model to Study the Effects of Inflammatory Stimuli on Cytochrome P450 Isoenzymes
      Katarina Rubin, Annika Janefeldt, Linda Andersson, Zsofia Berke, Ken Grime and Tommy B. Andersson
      Drug Metabolism and Disposition January 2015, 43 (1) 119-125; DOI: https://doi.org/10.1124/dmd.114.059246

  2. Gynther, Mikko

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

H

  1. Hagström, Marja

    1. Dog UDP-Glucuronosyltransferase Enzymes of Subfamily 1A: Cloning, Expression, and Activity
      Johanna Troberg, Erkka Järvinen, Maria Muniz, Nina Sneitz, Johanna Mosorin, Marja Hagström and Moshe Finel
      Drug Metabolism and Disposition January 2015, 43 (1) 107-118; DOI: https://doi.org/10.1124/dmd.114.059303

  2. Hakkarainen, Jenni J.

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

  3. Harder, Bryan G.

    1. Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
      Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2015, 43 (1) 93-99; DOI: https://doi.org/10.1124/dmd.114.060103

  4. Hosaka, Shinya

    1. Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2015, 43 (1) 27-33; DOI: https://doi.org/10.1124/dmd.114.061275

  5. Hosoya, Ken-ichi

    1. Involvement of the H+/Organic Cation Antiporter in Nicotine Transport in Rat Liver
      Yuma Tega, Shin-ichi Akanuma, Yoshiyuki Kubo and Ken-ichi Hosoya
      Drug Metabolism and Disposition January 2015, 43 (1) 89-92; DOI: https://doi.org/10.1124/dmd.114.061002

  6. Huang, Chenggang

    1. The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism
      Jingjing Sheng, Xiaoting Tian, Guanglin Xu, Zhitao Wu, Chen Chen, Le Wang, Lili Pan, Chenggang Huang and Guoyu Pan
      Drug Metabolism and Disposition January 2015, 43 (1) 63-72; DOI: https://doi.org/10.1124/dmd.114.059923

I

  1. Itin, Peter

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  2. Iwano, Shunsuke

    1. Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2015, 43 (1) 27-33; DOI: https://doi.org/10.1124/dmd.114.061275

  3. Iwasaki, Kazuhide

    1. Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2015, 43 (1) 27-33; DOI: https://doi.org/10.1124/dmd.114.061275

J

  1. Jackson, Jonathan P.

    1. Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
      Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2015, 43 (1) 93-99; DOI: https://doi.org/10.1124/dmd.114.060103

  2. Jalkanen, Aaro J.

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

  3. Janefeldt, Annika

    1. HepaRG Cells as Human-Relevant In Vitro Model to Study the Effects of Inflammatory Stimuli on Cytochrome P450 Isoenzymes
      Katarina Rubin, Annika Janefeldt, Linda Andersson, Zsofia Berke, Ken Grime and Tommy B. Andersson
      Drug Metabolism and Disposition January 2015, 43 (1) 119-125; DOI: https://doi.org/10.1124/dmd.114.059246

  4. Järvinen, Erkka

    1. Dog UDP-Glucuronosyltransferase Enzymes of Subfamily 1A: Cloning, Expression, and Activity
      Johanna Troberg, Erkka Järvinen, Maria Muniz, Nina Sneitz, Johanna Mosorin, Marja Hagström and Moshe Finel
      Drug Metabolism and Disposition January 2015, 43 (1) 107-118; DOI: https://doi.org/10.1124/dmd.114.059303

  5. Ji, Lin

    1. Imperatorin Is a Mechanism-Based Inactivator of CYP2B6
      Liwei Zheng, Jiaojiao Cao, Dan Lu, Lin Ji, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition January 2015, 43 (1) 82-88; DOI: https://doi.org/10.1124/dmd.114.060558

  6. Jin, Lu

    1. Assessing Steatotic Liver Function after Ischemia-Reperfusion Injury by In Vivo Multiphoton Imaging of Fluorescein Disposition
      Camilla A. Thorling, Lu Jin, Michael Weiss, Darrell Crawford, Xin Liu, Frank J. Burczynski, David Liu, Haolu Wang and Michael S. Roberts
      Drug Metabolism and Disposition January 2015, 43 (1) 154-162; DOI: https://doi.org/10.1124/dmd.114.060848

  7. Jones, Jeffrey P.

    1. Inhibition of Human Aldehyde Oxidase Activity by Diet-Derived Constituents: Structural Influence, Enzyme-Ligand Interactions, and Clinical Relevance
      John T. Barr, Jeffrey P. Jones, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition January 2015, 43 (1) 34-41; DOI: https://doi.org/10.1124/dmd.114.061192

K

  1. Kääriäinen, Tiina M.

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

  2. Kazmi, Faraz

    1. Anti-CD28 Monoclonal Antibody–Stimulated Cytokines Released from Blood Suppress CYP1A2, CYP2B6, and CYP3A4 in Human Hepatocytes In VitroGraphic
      Maciej Czerwiński, Faraz Kazmi, Andrew Parkinson and David B. Buckley
      Drug Metabolism and Disposition January 2015, 43 (1) 42-52; DOI: https://doi.org/10.1124/dmd.114.060186

  3. Kretz, Olivier

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  4. Kubo, Yoshiyuki

    1. Involvement of the H+/Organic Cation Antiporter in Nicotine Transport in Rat Liver
      Yuma Tega, Shin-ichi Akanuma, Yoshiyuki Kubo and Ken-ichi Hosoya
      Drug Metabolism and Disposition January 2015, 43 (1) 89-92; DOI: https://doi.org/10.1124/dmd.114.061002

  5. Kurkipuro, Jere

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

L

  1. Lam, Justine L

    1. Mechanistic Understanding of Translational Pharmacokinetic-Pharmacodynamic Relationships in Nonclinical Tumor Models: A Case Study of Orally Available Novel Inhibitors of Anaplastic Lymphoma Kinase
      Shinji Yamazaki, Justine L Lam, Helen Y Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Drug Metabolism and Disposition January 2015, 43 (1) 54-62; DOI: https://doi.org/10.1124/dmd.114.061143

  2. Leblond, François A.

    1. Effect of Experimental Kidney Disease on the Functional Expression of Hepatic Reductases
      Osama Y. Alshogran, Judith Naud, Andrew J. Ocque, François A. Leblond, Vincent Pichette and Thomas D. Nolin
      Drug Metabolism and Disposition January 2015, 43 (1) 100-106; DOI: https://doi.org/10.1124/dmd.114.061150

  3. Lehtonen, Marko

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

  4. Lévèques, Antoine

    1. Modulation of (–)-Epicatechin Metabolism by Coadministration with Other Polyphenols in Caco-2 Cell Model
      Belén Sanchez-Bridge, Antoine Lévèques, Hequn Li, Emmanuelle Bertschy, Amaury Patin and Lucas Actis-Goretta
      Drug Metabolism and Disposition January 2015, 43 (1) 9-16; DOI: https://doi.org/10.1124/dmd.114.060590

  5. Li, Hequn

    1. Modulation of (–)-Epicatechin Metabolism by Coadministration with Other Polyphenols in Caco-2 Cell Model
      Belén Sanchez-Bridge, Antoine Lévèques, Hequn Li, Emmanuelle Bertschy, Amaury Patin and Lucas Actis-Goretta
      Drug Metabolism and Disposition January 2015, 43 (1) 9-16; DOI: https://doi.org/10.1124/dmd.114.060590

  6. Lickteig, Andrew J.

    1. Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
      Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2015, 43 (1) 93-99; DOI: https://doi.org/10.1124/dmd.114.060103

  7. Lim, Heng-Keang

    1. A Nonradioactive Approach to Investigate the Metabolism of Therapeutic Peptides by Tagging with 127I and Using Inductively-Coupled Plasma Mass Spectrometry Analysis
      Heng-Keang Lim, Yuan Cao, Xi Qiu, Jose Silva and David C. Evans
      Drug Metabolism and Disposition January 2015, 43 (1) 17-26; DOI: https://doi.org/10.1124/dmd.114.059774

  8. Ling, Barbara

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  9. Litherland, Karine

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  10. Liu, David

    1. Assessing Steatotic Liver Function after Ischemia-Reperfusion Injury by In Vivo Multiphoton Imaging of Fluorescein Disposition
      Camilla A. Thorling, Lu Jin, Michael Weiss, Darrell Crawford, Xin Liu, Frank J. Burczynski, David Liu, Haolu Wang and Michael S. Roberts
      Drug Metabolism and Disposition January 2015, 43 (1) 154-162; DOI: https://doi.org/10.1124/dmd.114.060848

  11. Liu, Xin

    1. Assessing Steatotic Liver Function after Ischemia-Reperfusion Injury by In Vivo Multiphoton Imaging of Fluorescein Disposition
      Camilla A. Thorling, Lu Jin, Michael Weiss, Darrell Crawford, Xin Liu, Frank J. Burczynski, David Liu, Haolu Wang and Michael S. Roberts
      Drug Metabolism and Disposition January 2015, 43 (1) 154-162; DOI: https://doi.org/10.1124/dmd.114.060848

  12. Lu, Dan

    1. Imperatorin Is a Mechanism-Based Inactivator of CYP2B6
      Liwei Zheng, Jiaojiao Cao, Dan Lu, Lin Ji, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition January 2015, 43 (1) 82-88; DOI: https://doi.org/10.1124/dmd.114.060558

M

  1. Mackenzie, Peter I.

    1. Transporter-Mediated Uptake of UDP–Glucuronic Acid by Human Liver Microsomes: Assay Conditions, Kinetics, and Inhibition
      Andrew Rowland, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition January 2015, 43 (1) 147-153; DOI: https://doi.org/10.1124/dmd.114.060509

  2. Maher, Jonathan M.

    1. Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
      Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2015, 43 (1) 93-99; DOI: https://doi.org/10.1124/dmd.114.060103

  3. Manevski, Nenad

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  4. Merrell, Matthew D.

    1. Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
      Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2015, 43 (1) 93-99; DOI: https://doi.org/10.1124/dmd.114.060103

  5. Miners, John O.

    1. Transporter-Mediated Uptake of UDP–Glucuronic Acid by Human Liver Microsomes: Assay Conditions, Kinetics, and Inhibition
      Andrew Rowland, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition January 2015, 43 (1) 147-153; DOI: https://doi.org/10.1124/dmd.114.060509

  6. Morris, Marilyn E.

    1. Quantitative Structure-Pharmacokinetic Relationships for the Prediction of Renal Clearance in Humans
      Rutwij A. Dave and Marilyn E. Morris
      Drug Metabolism and Disposition January 2015, 43 (1) 73-81; DOI: https://doi.org/10.1124/dmd.114.059857

  7. Mosorin, Johanna

    1. Dog UDP-Glucuronosyltransferase Enzymes of Subfamily 1A: Cloning, Expression, and Activity
      Johanna Troberg, Erkka Järvinen, Maria Muniz, Nina Sneitz, Johanna Mosorin, Marja Hagström and Moshe Finel
      Drug Metabolism and Disposition January 2015, 43 (1) 107-118; DOI: https://doi.org/10.1124/dmd.114.059303

  8. Muniz, Maria

    1. Dog UDP-Glucuronosyltransferase Enzymes of Subfamily 1A: Cloning, Expression, and Activity
      Johanna Troberg, Erkka Järvinen, Maria Muniz, Nina Sneitz, Johanna Mosorin, Marja Hagström and Moshe Finel
      Drug Metabolism and Disposition January 2015, 43 (1) 107-118; DOI: https://doi.org/10.1124/dmd.114.059303

  9. Murayama, Norie

    1. Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2015, 43 (1) 27-33; DOI: https://doi.org/10.1124/dmd.114.061275

N

  1. Naud, Judith

    1. Effect of Experimental Kidney Disease on the Functional Expression of Hepatic Reductases
      Osama Y. Alshogran, Judith Naud, Andrew J. Ocque, François A. Leblond, Vincent Pichette and Thomas D. Nolin
      Drug Metabolism and Disposition January 2015, 43 (1) 100-106; DOI: https://doi.org/10.1124/dmd.114.061150

  2. Nolin, Thomas D.

    1. Effect of Experimental Kidney Disease on the Functional Expression of Hepatic Reductases
      Osama Y. Alshogran, Judith Naud, Andrew J. Ocque, François A. Leblond, Vincent Pichette and Thomas D. Nolin
      Drug Metabolism and Disposition January 2015, 43 (1) 100-106; DOI: https://doi.org/10.1124/dmd.114.061150

O

  1. Oberlies, Nicholas H.

    1. Inhibition of Human Aldehyde Oxidase Activity by Diet-Derived Constituents: Structural Influence, Enzyme-Ligand Interactions, and Clinical Relevance
      John T. Barr, Jeffrey P. Jones, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition January 2015, 43 (1) 34-41; DOI: https://doi.org/10.1124/dmd.114.061192

  2. Ocque, Andrew J.

    1. Effect of Experimental Kidney Disease on the Functional Expression of Hepatic Reductases
      Osama Y. Alshogran, Judith Naud, Andrew J. Ocque, François A. Leblond, Vincent Pichette and Thomas D. Nolin
      Drug Metabolism and Disposition January 2015, 43 (1) 100-106; DOI: https://doi.org/10.1124/dmd.114.061150

P

  1. Paine, Mary F.

    1. Inhibition of Human Aldehyde Oxidase Activity by Diet-Derived Constituents: Structural Influence, Enzyme-Ligand Interactions, and Clinical Relevance
      John T. Barr, Jeffrey P. Jones, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition January 2015, 43 (1) 34-41; DOI: https://doi.org/10.1124/dmd.114.061192

  2. Pan, Guoyu

    1. The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism
      Jingjing Sheng, Xiaoting Tian, Guanglin Xu, Zhitao Wu, Chen Chen, Le Wang, Lili Pan, Chenggang Huang and Guoyu Pan
      Drug Metabolism and Disposition January 2015, 43 (1) 63-72; DOI: https://doi.org/10.1124/dmd.114.059923

  3. Pan, Lili

    1. The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism
      Jingjing Sheng, Xiaoting Tian, Guanglin Xu, Zhitao Wu, Chen Chen, Le Wang, Lili Pan, Chenggang Huang and Guoyu Pan
      Drug Metabolism and Disposition January 2015, 43 (1) 63-72; DOI: https://doi.org/10.1124/dmd.114.059923

  4. Parkinson, Andrew

    1. Anti-CD28 Monoclonal Antibody–Stimulated Cytokines Released from Blood Suppress CYP1A2, CYP2B6, and CYP3A4 in Human Hepatocytes In VitroGraphic
      Maciej Czerwiński, Faraz Kazmi, Andrew Parkinson and David B. Buckley
      Drug Metabolism and Disposition January 2015, 43 (1) 42-52; DOI: https://doi.org/10.1124/dmd.114.060186

  5. Patin, Amaury

    1. Modulation of (–)-Epicatechin Metabolism by Coadministration with Other Polyphenols in Caco-2 Cell Model
      Belén Sanchez-Bridge, Antoine Lévèques, Hequn Li, Emmanuelle Bertschy, Amaury Patin and Lucas Actis-Goretta
      Drug Metabolism and Disposition January 2015, 43 (1) 9-16; DOI: https://doi.org/10.1124/dmd.114.060590

  6. Peng, Ying

    1. Imperatorin Is a Mechanism-Based Inactivator of CYP2B6
      Liwei Zheng, Jiaojiao Cao, Dan Lu, Lin Ji, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition January 2015, 43 (1) 82-88; DOI: https://doi.org/10.1124/dmd.114.060558

  7. Petsalo, Aleksanteri

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

  8. Peura, Lauri

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

  9. Pichette, Vincent

    1. Effect of Experimental Kidney Disease on the Functional Expression of Hepatic Reductases
      Osama Y. Alshogran, Judith Naud, Andrew J. Ocque, François A. Leblond, Vincent Pichette and Thomas D. Nolin
      Drug Metabolism and Disposition January 2015, 43 (1) 100-106; DOI: https://doi.org/10.1124/dmd.114.061150

  10. Pognan, Francois

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

Q

  1. Qiu, Xi

    1. A Nonradioactive Approach to Investigate the Metabolism of Therapeutic Peptides by Tagging with 127I and Using Inductively-Coupled Plasma Mass Spectrometry Analysis
      Heng-Keang Lim, Yuan Cao, Xi Qiu, Jose Silva and David C. Evans
      Drug Metabolism and Disposition January 2015, 43 (1) 17-26; DOI: https://doi.org/10.1124/dmd.114.059774

R

  1. Rautio, Jarkko

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

  2. Roberts, Michael S.

    1. Assessing Steatotic Liver Function after Ischemia-Reperfusion Injury by In Vivo Multiphoton Imaging of Fluorescein Disposition
      Camilla A. Thorling, Lu Jin, Michael Weiss, Darrell Crawford, Xin Liu, Frank J. Burczynski, David Liu, Haolu Wang and Michael S. Roberts
      Drug Metabolism and Disposition January 2015, 43 (1) 154-162; DOI: https://doi.org/10.1124/dmd.114.060848

  3. Rowland, Andrew

    1. Transporter-Mediated Uptake of UDP–Glucuronic Acid by Human Liver Microsomes: Assay Conditions, Kinetics, and Inhibition
      Andrew Rowland, Peter I. Mackenzie and John O. Miners
      Drug Metabolism and Disposition January 2015, 43 (1) 147-153; DOI: https://doi.org/10.1124/dmd.114.060509

  4. Rubin, Katarina

    1. HepaRG Cells as Human-Relevant In Vitro Model to Study the Effects of Inflammatory Stimuli on Cytochrome P450 Isoenzymes
      Katarina Rubin, Annika Janefeldt, Linda Andersson, Zsofia Berke, Ken Grime and Tommy B. Andersson
      Drug Metabolism and Disposition January 2015, 43 (1) 119-125; DOI: https://doi.org/10.1124/dmd.114.059246

S

  1. Samaranayake, Haritha

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

  2. Sanchez-Bridge, Belén

    1. Modulation of (–)-Epicatechin Metabolism by Coadministration with Other Polyphenols in Caco-2 Cell Model
      Belén Sanchez-Bridge, Antoine Lévèques, Hequn Li, Emmanuelle Bertschy, Amaury Patin and Lucas Actis-Goretta
      Drug Metabolism and Disposition January 2015, 43 (1) 9-16; DOI: https://doi.org/10.1124/dmd.114.060590

  3. Satsukawa, Masahiro

    1. Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2015, 43 (1) 27-33; DOI: https://doi.org/10.1124/dmd.114.061275

  4. Schaefer, Dirk J.

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  5. Schiller, Hilmar

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  6. Sheng, Jingjing

    1. The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism
      Jingjing Sheng, Xiaoting Tian, Guanglin Xu, Zhitao Wu, Chen Chen, Le Wang, Lili Pan, Chenggang Huang and Guoyu Pan
      Drug Metabolism and Disposition January 2015, 43 (1) 63-72; DOI: https://doi.org/10.1124/dmd.114.059923

  7. Shimizu, Makiko

    1. Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2015, 43 (1) 27-33; DOI: https://doi.org/10.1124/dmd.114.061275

  8. Silva, Jose

    1. A Nonradioactive Approach to Investigate the Metabolism of Therapeutic Peptides by Tagging with 127I and Using Inductively-Coupled Plasma Mass Spectrometry Analysis
      Heng-Keang Lim, Yuan Cao, Xi Qiu, Jose Silva and David C. Evans
      Drug Metabolism and Disposition January 2015, 43 (1) 17-26; DOI: https://doi.org/10.1124/dmd.114.059774

  9. Smeal, Tod

    1. Mechanistic Understanding of Translational Pharmacokinetic-Pharmacodynamic Relationships in Nonclinical Tumor Models: A Case Study of Orally Available Novel Inhibitors of Anaplastic Lymphoma Kinase
      Shinji Yamazaki, Justine L Lam, Helen Y Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Drug Metabolism and Disposition January 2015, 43 (1) 54-62; DOI: https://doi.org/10.1124/dmd.114.061143

  10. Sneitz, Nina

    1. Dog UDP-Glucuronosyltransferase Enzymes of Subfamily 1A: Cloning, Expression, and Activity
      Johanna Troberg, Erkka Järvinen, Maria Muniz, Nina Sneitz, Johanna Mosorin, Marja Hagström and Moshe Finel
      Drug Metabolism and Disposition January 2015, 43 (1) 107-118; DOI: https://doi.org/10.1124/dmd.114.059303

  11. Swart, Piet

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

T

  1. Tega, Yuma

    1. Involvement of the H+/Organic Cation Antiporter in Nicotine Transport in Rat Liver
      Yuma Tega, Shin-ichi Akanuma, Yoshiyuki Kubo and Ken-ichi Hosoya
      Drug Metabolism and Disposition January 2015, 43 (1) 89-92; DOI: https://doi.org/10.1124/dmd.114.061002

  2. Thorling, Camilla A.

    1. Assessing Steatotic Liver Function after Ischemia-Reperfusion Injury by In Vivo Multiphoton Imaging of Fluorescein Disposition
      Camilla A. Thorling, Lu Jin, Michael Weiss, Darrell Crawford, Xin Liu, Frank J. Burczynski, David Liu, Haolu Wang and Michael S. Roberts
      Drug Metabolism and Disposition January 2015, 43 (1) 154-162; DOI: https://doi.org/10.1124/dmd.114.060848

  3. Tian, Xiaoting

    1. The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism
      Jingjing Sheng, Xiaoting Tian, Guanglin Xu, Zhitao Wu, Chen Chen, Le Wang, Lili Pan, Chenggang Huang and Guoyu Pan
      Drug Metabolism and Disposition January 2015, 43 (1) 63-72; DOI: https://doi.org/10.1124/dmd.114.059923

  4. Troberg, Johanna

    1. Dog UDP-Glucuronosyltransferase Enzymes of Subfamily 1A: Cloning, Expression, and Activity
      Johanna Troberg, Erkka Järvinen, Maria Muniz, Nina Sneitz, Johanna Mosorin, Marja Hagström and Moshe Finel
      Drug Metabolism and Disposition January 2015, 43 (1) 107-118; DOI: https://doi.org/10.1124/dmd.114.059303

U

  1. Uehara, Shotaro

    1. Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2015, 43 (1) 27-33; DOI: https://doi.org/10.1124/dmd.114.061275

  2. Uno, Yasuhiro

    1. Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2015, 43 (1) 27-33; DOI: https://doi.org/10.1124/dmd.114.061275

V

  1. Vicini, Paolo

    1. Mechanistic Understanding of Translational Pharmacokinetic-Pharmacodynamic Relationships in Nonclinical Tumor Models: A Case Study of Orally Available Novel Inhibitors of Anaplastic Lymphoma Kinase
      Shinji Yamazaki, Justine L Lam, Helen Y Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Drug Metabolism and Disposition January 2015, 43 (1) 54-62; DOI: https://doi.org/10.1124/dmd.114.061143

W

  1. Walles, Markus

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  2. Wang, Haolu

    1. Assessing Steatotic Liver Function after Ischemia-Reperfusion Injury by In Vivo Multiphoton Imaging of Fluorescein Disposition
      Camilla A. Thorling, Lu Jin, Michael Weiss, Darrell Crawford, Xin Liu, Frank J. Burczynski, David Liu, Haolu Wang and Michael S. Roberts
      Drug Metabolism and Disposition January 2015, 43 (1) 154-162; DOI: https://doi.org/10.1124/dmd.114.060848

  3. Wang, Hui

    1. Mechanistic Understanding of Translational Pharmacokinetic-Pharmacodynamic Relationships in Nonclinical Tumor Models: A Case Study of Orally Available Novel Inhibitors of Anaplastic Lymphoma Kinase
      Shinji Yamazaki, Justine L Lam, Helen Y Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Drug Metabolism and Disposition January 2015, 43 (1) 54-62; DOI: https://doi.org/10.1124/dmd.114.061143

  4. Wang, Le

    1. The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism
      Jingjing Sheng, Xiaoting Tian, Guanglin Xu, Zhitao Wu, Chen Chen, Le Wang, Lili Pan, Chenggang Huang and Guoyu Pan
      Drug Metabolism and Disposition January 2015, 43 (1) 63-72; DOI: https://doi.org/10.1124/dmd.114.059923

  5. Weiss, Michael

    1. Assessing Steatotic Liver Function after Ischemia-Reperfusion Injury by In Vivo Multiphoton Imaging of Fluorescein Disposition
      Camilla A. Thorling, Lu Jin, Michael Weiss, Darrell Crawford, Xin Liu, Frank J. Burczynski, David Liu, Haolu Wang and Michael S. Roberts
      Drug Metabolism and Disposition January 2015, 43 (1) 154-162; DOI: https://doi.org/10.1124/dmd.114.060848

  6. Wettstein, Reto

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  7. Wolf, Armin

    1. Phase II Metabolism in Human Skin: Skin Explants Show Full Coverage for Glucuronidation, Sulfation, N-Acetylation, Catechol Methylation, and Glutathione Conjugation
      Nenad Manevski, Piet Swart, Kamal Kumar Balavenkatraman, Barbara Bertschi, Gian Camenisch, Olivier Kretz, Hilmar Schiller, Markus Walles, Barbara Ling, Reto Wettstein, Dirk J. Schaefer, Peter Itin, Joanna Ashton-Chess, Francois Pognan, Armin Wolf and Karine Litherland
      Drug Metabolism and Disposition January 2015, 43 (1) 126-139; DOI: https://doi.org/10.1124/dmd.114.060350

  8. Wu, Tongde

    1. Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
      Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2015, 43 (1) 93-99; DOI: https://doi.org/10.1124/dmd.114.060103

  9. Wu, Zhitao

    1. The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism
      Jingjing Sheng, Xiaoting Tian, Guanglin Xu, Zhitao Wu, Chen Chen, Le Wang, Lili Pan, Chenggang Huang and Guoyu Pan
      Drug Metabolism and Disposition January 2015, 43 (1) 63-72; DOI: https://doi.org/10.1124/dmd.114.059923

X

  1. Xu, Guanglin

    1. The Hepatobiliary Disposition of Timosaponin B2 Is Highly Dependent on Influx/Efflux Transporters but Not Metabolism
      Jingjing Sheng, Xiaoting Tian, Guanglin Xu, Zhitao Wu, Chen Chen, Le Wang, Lili Pan, Chenggang Huang and Guoyu Pan
      Drug Metabolism and Disposition January 2015, 43 (1) 63-72; DOI: https://doi.org/10.1124/dmd.114.059923

Y

  1. Yamamoto, Masayuki

    1. Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
      Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2015, 43 (1) 93-99; DOI: https://doi.org/10.1124/dmd.114.060103

  2. Yamazaki, Hiroshi

    1. Evaluation of 89 Compounds for Identification of Substrates for Cynomolgus Monkey CYP2C76, a New Bupropion/Nifedipine Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Makiko Shimizu, Shotaro Uehara, Hideki Fujino, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition January 2015, 43 (1) 27-33; DOI: https://doi.org/10.1124/dmd.114.061275

  3. Yamazaki, Shinji

    1. Mechanistic Understanding of Translational Pharmacokinetic-Pharmacodynamic Relationships in Nonclinical Tumor Models: A Case Study of Orally Available Novel Inhibitors of Anaplastic Lymphoma Kinase
      Shinji Yamazaki, Justine L Lam, Helen Y Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Drug Metabolism and Disposition January 2015, 43 (1) 54-62; DOI: https://doi.org/10.1124/dmd.114.061143

  4. Ylä-Herttuala, Seppo

    1. Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma
      Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
      Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

  5. Youdim, Kuresh

    1. Reaction Phenotyping: Advances in the Experimental Strategies Used to Characterize the Contribution of Drug-Metabolizing Enzymes
      Michael A. Zientek and Kuresh Youdim
      Drug Metabolism and Disposition January 2015, 43 (1) 163-181; DOI: https://doi.org/10.1124/dmd.114.058750

Z

  1. Zhang, Donna D.

    1. Identification of a Functional Antioxidant Response Element within the Eighth Intron of the Human ABCC3 Gene
      Mark J. Canet, Matthew D. Merrell, Bryan G. Harder, Jonathan M. Maher, Tongde Wu, Andrew J. Lickteig, Jonathan P. Jackson, Donna D. Zhang, Masayuki Yamamoto and Nathan J. Cherrington
      Drug Metabolism and Disposition January 2015, 43 (1) 93-99; DOI: https://doi.org/10.1124/dmd.114.060103

  2. Zheng, Jiang

    1. Imperatorin Is a Mechanism-Based Inactivator of CYP2B6
      Liwei Zheng, Jiaojiao Cao, Dan Lu, Lin Ji, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition January 2015, 43 (1) 82-88; DOI: https://doi.org/10.1124/dmd.114.060558

  3. Zheng, Liwei

    1. Imperatorin Is a Mechanism-Based Inactivator of CYP2B6
      Liwei Zheng, Jiaojiao Cao, Dan Lu, Lin Ji, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition January 2015, 43 (1) 82-88; DOI: https://doi.org/10.1124/dmd.114.060558

  4. Zientek, Michael A.

    1. Reaction Phenotyping: Advances in the Experimental Strategies Used to Characterize the Contribution of Drug-Metabolizing Enzymes
      Michael A. Zientek and Kuresh Youdim
      Drug Metabolism and Disposition January 2015, 43 (1) 163-181; DOI: https://doi.org/10.1124/dmd.114.058750

  5. Zou, Helen Y

    1. Mechanistic Understanding of Translational Pharmacokinetic-Pharmacodynamic Relationships in Nonclinical Tumor Models: A Case Study of Orally Available Novel Inhibitors of Anaplastic Lymphoma Kinase
      Shinji Yamazaki, Justine L Lam, Helen Y Zou, Hui Wang, Tod Smeal and Paolo Vicini
      Drug Metabolism and Disposition January 2015, 43 (1) 54-62; DOI: https://doi.org/10.1124/dmd.114.061143
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