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Research ArticleArticle

Brain Pharmacokinetics of Ganciclovir in Rats with Orthotopic BT4C Glioma

Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
Drug Metabolism and Disposition January 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840
Mikko Gynther
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Tiina M. Kääriäinen
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Jenni J. Hakkarainen
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Aaro J. Jalkanen
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Aleksanteri Petsalo
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Marko Lehtonen
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Lauri Peura
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Jere Kurkipuro
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Haritha Samaranayake
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Seppo Ylä-Herttuala
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Jarkko Rautio
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Markus M. Forsberg
Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
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Article Information

vol. 43 no. 1 140-146
DOI 
https://doi.org/10.1124/dmd.114.059840
PubMed 
25349125

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received July 4, 2014
  • Accepted October 27, 2014
  • Published online November 24, 2014.

Article Versions

  • Earlier version (October 27, 2014 - 08:57).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2014 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Mikko Gynther,
  2. Tiina M. Kääriäinen,
  3. Jenni J. Hakkarainen,
  4. Aaro J. Jalkanen,
  5. Aleksanteri Petsalo,
  6. Marko Lehtonen,
  7. Lauri Peura,
  8. Jere Kurkipuro,
  9. Haritha Samaranayake1,
  10. Seppo Ylä-Herttuala,
  11. Jarkko Rautio, and
  12. Markus M. Forsberg
  1. Faculty of Health Sciences, School of Pharmacy (M.G., T.M.K., J.J.H., A.J.J., A.P., M.L., L.P., J.R., M.M.F.) and A. I. Virtanen Institute for Molecular Sciences (J.K., H.S., S.Y.-H.), University of Eastern Finland, Kuopio, Finland
  1. Address correspondence to:
    Mikko Gynther, School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Yliopistonranta 1 C, 70211 Kuopio, Finland. E-mail: mikko.gynther{at}uef.fi
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Drug Metabolism and Disposition: 43 (1)
Drug Metabolism and Disposition
Vol. 43, Issue 1
1 Jan 2015
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Research ArticleArticle

Brain Pharmacokinetics of Ganciclovir

Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
Drug Metabolism and Disposition January 1, 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840

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Research ArticleArticle

Brain Pharmacokinetics of Ganciclovir

Mikko Gynther, Tiina M. Kääriäinen, Jenni J. Hakkarainen, Aaro J. Jalkanen, Aleksanteri Petsalo, Marko Lehtonen, Lauri Peura, Jere Kurkipuro, Haritha Samaranayake, Seppo Ylä-Herttuala, Jarkko Rautio and Markus M. Forsberg
Drug Metabolism and Disposition January 1, 2015, 43 (1) 140-146; DOI: https://doi.org/10.1124/dmd.114.059840
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