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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
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Index by author

October 01, 2015; Volume 43,Issue 10
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Allred, Clint D.

    1. You have access
      Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes
      Yating Cheng, Un-Ho Jin, Clint D. Allred, Arul Jayaraman, Robert S. Chapkin and Stephen Safe
      Drug Metabolism and Disposition October 2015, 43 (10) 1536-1543; DOI: https://doi.org/10.1124/dmd.115.063677
  2. Aoki, Yasuhiro

    1. You have access
      Single-Nucleotide Polymorphisms in Cytochrome P450 2E1 (CYP2E1) 3′-Untranslated Region Affect the Regulation of CYP2E1 by miR-570
      Masataka Nakano, Takuya Mohri, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Howard L. McLeod and Miki Nakajima
      Drug Metabolism and Disposition October 2015, 43 (10) 1450-1457; DOI: https://doi.org/10.1124/dmd.115.065664

B

  1. Beaton, Melanie D.

    1. You have access
      CYP3A Activity and Expression in Nonalcoholic Fatty Liver Disease
      Sarah J. Woolsey, Sara E. Mansell, Richard B. Kim, Rommel G. Tirona and Melanie D. Beaton
      Drug Metabolism and Disposition October 2015, 43 (10) 1484-1490; DOI: https://doi.org/10.1124/dmd.115.065979
  2. Brown-Augsburger, Patricia L.

    1. You have access
      Disposition of Basal Insulin Peglispro Compared with 20-kDa Polyethylene Glycol in Rats Following a Single Intravenous or Subcutaneous Dose
      Mary Pat Knadler, Bernice B. Ellis, Patricia L. Brown-Augsburger, Anthony T. Murphy, Jennifer A. Martin and Victor J. Wroblewski
      Drug Metabolism and Disposition October 2015, 43 (10) 1477-1483; DOI: https://doi.org/10.1124/dmd.115.064337

C

  1. Chan, Eric Chun Yong

    1. You have access
      Investigation of Host–Gut Microbiota Modulation of Therapeutic Outcome
      Lian Yee Yip and Eric Chun Yong Chan
      Drug Metabolism and Disposition October 2015, 43 (10) 1619-1631; DOI: https://doi.org/10.1124/dmd.115.063750
  2. Chapkin, Robert S.

    1. You have access
      Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes
      Yating Cheng, Un-Ho Jin, Clint D. Allred, Arul Jayaraman, Robert S. Chapkin and Stephen Safe
      Drug Metabolism and Disposition October 2015, 43 (10) 1536-1543; DOI: https://doi.org/10.1124/dmd.115.063677
  3. Chau, Nuy

    1. You have access
      Inhibition of Human UDP-Glucuronosyltransferase Enzymes by Canagliflozin and Dapagliflozin: Implications for Drug-Drug Interactions
      Attarat Pattanawongsa, Nuy Chau, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition October 2015, 43 (10) 1468-1476; DOI: https://doi.org/10.1124/dmd.115.065870
  4. Chen, Qingmei

    1. Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1<em>α</em>, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      You have access
      Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1α, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      Linfeng Dong, Qingmei Chen, Xin Liu, Jikai Wen, Jun Jiang and Yiqun Deng
      Drug Metabolism and Disposition October 2015, 43 (10) 1458-1467; DOI: https://doi.org/10.1124/dmd.115.065565
  5. Chen, Xiaoyan

    1. You have access
      Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel
      Cai Liu, Zhaoqiang Chen, Kan Zhong, Liang Li, Weiliang Zhu, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2015, 43 (10) 1632-1641; DOI: https://doi.org/10.1124/dmd.115.064949
  6. Chen, Yan

    1. Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      You have access
      Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      Jing Zhou, Yi Hua Ma, Zhong Zhou, Yan Chen, Ying Wang and Xia Gao
      Drug Metabolism and Disposition October 2015, 43 (10) 1590-1600; DOI: https://doi.org/10.1124/dmd.115.064386
  7. Chen, Zhaoqiang

    1. You have access
      Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel
      Cai Liu, Zhaoqiang Chen, Kan Zhong, Liang Li, Weiliang Zhu, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2015, 43 (10) 1632-1641; DOI: https://doi.org/10.1124/dmd.115.064949
  8. Cheng, Yating

    1. You have access
      Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes
      Yating Cheng, Un-Ho Jin, Clint D. Allred, Arul Jayaraman, Robert S. Chapkin and Stephen Safe
      Drug Metabolism and Disposition October 2015, 43 (10) 1536-1543; DOI: https://doi.org/10.1124/dmd.115.063677
  9. Clark, Alex M.

    1. Making Transporter Models for Drug–Drug Interaction Prediction Mobile
      You have access
      Making Transporter Models for Drug–Drug Interaction Prediction Mobile
      Sean Ekins, Alex M. Clark and Stephen H. Wright
      Drug Metabolism and Disposition October 2015, 43 (10) 1642-1645; DOI: https://doi.org/10.1124/dmd.115.064956
  10. Csanaky, Iván L.

    1. You have access
      Importance of Large Intestine in Regulating Bile Acids and Glucagon-Like Peptide-1 in Germ-Free Mice
      Felcy Pavithra Selwyn, Iván L. Csanaky, Youcai Zhang and Curtis D. Klaassen
      Drug Metabolism and Disposition October 2015, 43 (10) 1544-1556; DOI: https://doi.org/10.1124/dmd.115.065276
  11. Cui, Julia Yue

    1. You have access
      Review: Mechanisms of How the Intestinal Microbiota Alters the Effects of Drugs and Bile Acids
      Curtis D. Klaassen and Julia Yue Cui
      Drug Metabolism and Disposition October 2015, 43 (10) 1505-1521; DOI: https://doi.org/10.1124/dmd.115.065698
    2. You have access
      RNA-Seq Quantification of Hepatic Drug Processing Genes in Germ-Free Mice
      Felcy Pavithra Selwyn, Julia Yue Cui and Curtis D. Klaassen
      Drug Metabolism and Disposition October 2015, 43 (10) 1572-1580; DOI: https://doi.org/10.1124/dmd.115.063545

D

  1. Deng, Yiqun

    1. Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1<em>α</em>, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      You have access
      Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1α, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      Linfeng Dong, Qingmei Chen, Xin Liu, Jikai Wen, Jun Jiang and Yiqun Deng
      Drug Metabolism and Disposition October 2015, 43 (10) 1458-1467; DOI: https://doi.org/10.1124/dmd.115.065565
  2. Dong, Linfeng

    1. Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1<em>α</em>, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      You have access
      Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1α, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      Linfeng Dong, Qingmei Chen, Xin Liu, Jikai Wen, Jun Jiang and Yiqun Deng
      Drug Metabolism and Disposition October 2015, 43 (10) 1458-1467; DOI: https://doi.org/10.1124/dmd.115.065565

E

  1. Ekins, Sean

    1. Making Transporter Models for Drug–Drug Interaction Prediction Mobile
      You have access
      Making Transporter Models for Drug–Drug Interaction Prediction Mobile
      Sean Ekins, Alex M. Clark and Stephen H. Wright
      Drug Metabolism and Disposition October 2015, 43 (10) 1642-1645; DOI: https://doi.org/10.1124/dmd.115.064956
  2. Ellis, Bernice B.

    1. You have access
      Disposition of Basal Insulin Peglispro Compared with 20-kDa Polyethylene Glycol in Rats Following a Single Intravenous or Subcutaneous Dose
      Mary Pat Knadler, Bernice B. Ellis, Patricia L. Brown-Augsburger, Anthony T. Murphy, Jennifer A. Martin and Victor J. Wroblewski
      Drug Metabolism and Disposition October 2015, 43 (10) 1477-1483; DOI: https://doi.org/10.1124/dmd.115.064337

F

  1. Fukami, Tatsuki

    1. You have access
      Single-Nucleotide Polymorphisms in Cytochrome P450 2E1 (CYP2E1) 3′-Untranslated Region Affect the Regulation of CYP2E1 by miR-570
      Masataka Nakano, Takuya Mohri, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Howard L. McLeod and Miki Nakajima
      Drug Metabolism and Disposition October 2015, 43 (10) 1450-1457; DOI: https://doi.org/10.1124/dmd.115.065664

G

  1. Gao, Xia

    1. Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      You have access
      Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      Jing Zhou, Yi Hua Ma, Zhong Zhou, Yan Chen, Ying Wang and Xia Gao
      Drug Metabolism and Disposition October 2015, 43 (10) 1590-1600; DOI: https://doi.org/10.1124/dmd.115.064386
  2. Gu, Chungang

    1. Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      You have access
      Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      Chungang Gu, Richard J. Lewis, Andrew S. Wells, Per H. Svensson, Vinayak P. Hosagrahara, Eskil Johnsson and Gösta Hallström
      Drug Metabolism and Disposition October 2015, 43 (10) 1441-1449; DOI: https://doi.org/10.1124/dmd.115.065136

H

  1. Hallström, Gösta

    1. Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      You have access
      Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      Chungang Gu, Richard J. Lewis, Andrew S. Wells, Per H. Svensson, Vinayak P. Hosagrahara, Eskil Johnsson and Gösta Hallström
      Drug Metabolism and Disposition October 2015, 43 (10) 1441-1449; DOI: https://doi.org/10.1124/dmd.115.065136
  2. Hosagrahara, Vinayak P.

    1. Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      You have access
      Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      Chungang Gu, Richard J. Lewis, Andrew S. Wells, Per H. Svensson, Vinayak P. Hosagrahara, Eskil Johnsson and Gösta Hallström
      Drug Metabolism and Disposition October 2015, 43 (10) 1441-1449; DOI: https://doi.org/10.1124/dmd.115.065136
  3. Hubbard, Troy D.

    1. You have access
      Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation
      Troy D. Hubbard, Iain A. Murray and Gary H. Perdew
      Drug Metabolism and Disposition October 2015, 43 (10) 1522-1535; DOI: https://doi.org/10.1124/dmd.115.064246

I

  1. Inoue, Takashi

    1. Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, <em>S</em>-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      You have access
      Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition October 2015, 43 (10) 1408-1416; DOI: https://doi.org/10.1124/dmd.115.066100

J

  1. Jayaraman, Arul

    1. You have access
      Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes
      Yating Cheng, Un-Ho Jin, Clint D. Allred, Arul Jayaraman, Robert S. Chapkin and Stephen Safe
      Drug Metabolism and Disposition October 2015, 43 (10) 1536-1543; DOI: https://doi.org/10.1124/dmd.115.063677
  2. Jiang, Jun

    1. Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1<em>α</em>, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      You have access
      Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1α, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      Linfeng Dong, Qingmei Chen, Xin Liu, Jikai Wen, Jun Jiang and Yiqun Deng
      Drug Metabolism and Disposition October 2015, 43 (10) 1458-1467; DOI: https://doi.org/10.1124/dmd.115.065565
  3. Jin, Un-Ho

    1. You have access
      Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes
      Yating Cheng, Un-Ho Jin, Clint D. Allred, Arul Jayaraman, Robert S. Chapkin and Stephen Safe
      Drug Metabolism and Disposition October 2015, 43 (10) 1536-1543; DOI: https://doi.org/10.1124/dmd.115.063677
  4. Johnson, Theodore R.

    1. Prediction of Drug-Drug Interactions with Crizotinib as the CYP3A Substrate Using a Physiologically Based Pharmacokinetic Model
      You have access
      Prediction of Drug-Drug Interactions with Crizotinib as the CYP3A Substrate Using a Physiologically Based Pharmacokinetic Model
      Shinji Yamazaki, Theodore R. Johnson and Bill J. Smith
      Drug Metabolism and Disposition October 2015, 43 (10) 1417-1429; DOI: https://doi.org/10.1124/dmd.115.064618
  5. Johnsson, Eskil

    1. Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      You have access
      Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      Chungang Gu, Richard J. Lewis, Andrew S. Wells, Per H. Svensson, Vinayak P. Hosagrahara, Eskil Johnsson and Gösta Hallström
      Drug Metabolism and Disposition October 2015, 43 (10) 1441-1449; DOI: https://doi.org/10.1124/dmd.115.065136
  6. Johnstone, Nicholas

    1. You have access
      Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies
      Michelle McCabe, Rucha S. Sane, Monica Keith-Luzzi, Jun Xu, Illeaniz King, Andrea Whitcher-Johnstone, Nicholas Johnstone, Donald J. Tweedie and Yongmei Li
      Drug Metabolism and Disposition October 2015, 43 (10) 1612-1618; DOI: https://doi.org/10.1124/dmd.115.064477

K

  1. Kawano, Mirai

    1. Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, <em>S</em>-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      You have access
      Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition October 2015, 43 (10) 1408-1416; DOI: https://doi.org/10.1124/dmd.115.066100
  2. Keith-Luzzi, Monica

    1. You have access
      Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies
      Michelle McCabe, Rucha S. Sane, Monica Keith-Luzzi, Jun Xu, Illeaniz King, Andrea Whitcher-Johnstone, Nicholas Johnstone, Donald J. Tweedie and Yongmei Li
      Drug Metabolism and Disposition October 2015, 43 (10) 1612-1618; DOI: https://doi.org/10.1124/dmd.115.064477
  3. Kim, Dong-Hyun

    1. You have access
      Gut Microbiota-Mediated Drug-Antibiotic Interactions
      Dong-Hyun Kim
      Drug Metabolism and Disposition October 2015, 43 (10) 1581-1589; DOI: https://doi.org/10.1124/dmd.115.063867
  4. Kim, Richard B.

    1. You have access
      CYP3A Activity and Expression in Nonalcoholic Fatty Liver Disease
      Sarah J. Woolsey, Sara E. Mansell, Richard B. Kim, Rommel G. Tirona and Melanie D. Beaton
      Drug Metabolism and Disposition October 2015, 43 (10) 1484-1490; DOI: https://doi.org/10.1124/dmd.115.065979
  5. King, Illeaniz

    1. You have access
      Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies
      Michelle McCabe, Rucha S. Sane, Monica Keith-Luzzi, Jun Xu, Illeaniz King, Andrea Whitcher-Johnstone, Nicholas Johnstone, Donald J. Tweedie and Yongmei Li
      Drug Metabolism and Disposition October 2015, 43 (10) 1612-1618; DOI: https://doi.org/10.1124/dmd.115.064477
  6. Klaassen, Curtis D.

    1. You have access
      Review: Mechanisms of How the Intestinal Microbiota Alters the Effects of Drugs and Bile Acids
      Curtis D. Klaassen and Julia Yue Cui
      Drug Metabolism and Disposition October 2015, 43 (10) 1505-1521; DOI: https://doi.org/10.1124/dmd.115.065698
    2. You have access
      RNA-Seq Quantification of Hepatic Drug Processing Genes in Germ-Free Mice
      Felcy Pavithra Selwyn, Julia Yue Cui and Curtis D. Klaassen
      Drug Metabolism and Disposition October 2015, 43 (10) 1572-1580; DOI: https://doi.org/10.1124/dmd.115.063545
    3. You have access
      Importance of Large Intestine in Regulating Bile Acids and Glucagon-Like Peptide-1 in Germ-Free Mice
      Felcy Pavithra Selwyn, Iván L. Csanaky, Youcai Zhang and Curtis D. Klaassen
      Drug Metabolism and Disposition October 2015, 43 (10) 1544-1556; DOI: https://doi.org/10.1124/dmd.115.065276
  7. Knadler, Mary Pat

    1. You have access
      Disposition of Basal Insulin Peglispro Compared with 20-kDa Polyethylene Glycol in Rats Following a Single Intravenous or Subcutaneous Dose
      Mary Pat Knadler, Bernice B. Ellis, Patricia L. Brown-Augsburger, Anthony T. Murphy, Jennifer A. Martin and Victor J. Wroblewski
      Drug Metabolism and Disposition October 2015, 43 (10) 1477-1483; DOI: https://doi.org/10.1124/dmd.115.064337

L

  1. Lee, Simon Ming-Yuen

    1. You have access
      The Presystemic Interplay between Gut Microbiota and Orally Administered Calycosin-7-O-β-d-Glucoside
      Jian-Qing Ruan, Shang Li, Ya-Ping Li, Wen-Jin Wu, Simon Ming-Yuen Lee and Ru Yan
      Drug Metabolism and Disposition October 2015, 43 (10) 1601-1611; DOI: https://doi.org/10.1124/dmd.115.065094
  2. Lewis, Richard J.

    1. Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      You have access
      Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      Chungang Gu, Richard J. Lewis, Andrew S. Wells, Per H. Svensson, Vinayak P. Hosagrahara, Eskil Johnsson and Gösta Hallström
      Drug Metabolism and Disposition October 2015, 43 (10) 1441-1449; DOI: https://doi.org/10.1124/dmd.115.065136
  3. Li, Liang

    1. You have access
      Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel
      Cai Liu, Zhaoqiang Chen, Kan Zhong, Liang Li, Weiliang Zhu, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2015, 43 (10) 1632-1641; DOI: https://doi.org/10.1124/dmd.115.064949
  4. Li, Shang

    1. You have access
      The Presystemic Interplay between Gut Microbiota and Orally Administered Calycosin-7-O-β-d-Glucoside
      Jian-Qing Ruan, Shang Li, Ya-Ping Li, Wen-Jin Wu, Simon Ming-Yuen Lee and Ru Yan
      Drug Metabolism and Disposition October 2015, 43 (10) 1601-1611; DOI: https://doi.org/10.1124/dmd.115.065094
  5. Li, Ya-Ping

    1. You have access
      The Presystemic Interplay between Gut Microbiota and Orally Administered Calycosin-7-O-β-d-Glucoside
      Jian-Qing Ruan, Shang Li, Ya-Ping Li, Wen-Jin Wu, Simon Ming-Yuen Lee and Ru Yan
      Drug Metabolism and Disposition October 2015, 43 (10) 1601-1611; DOI: https://doi.org/10.1124/dmd.115.065094
  6. Li, Yongmei

    1. You have access
      Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies
      Michelle McCabe, Rucha S. Sane, Monica Keith-Luzzi, Jun Xu, Illeaniz King, Andrea Whitcher-Johnstone, Nicholas Johnstone, Donald J. Tweedie and Yongmei Li
      Drug Metabolism and Disposition October 2015, 43 (10) 1612-1618; DOI: https://doi.org/10.1124/dmd.115.064477
  7. Liu, Cai

    1. You have access
      Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel
      Cai Liu, Zhaoqiang Chen, Kan Zhong, Liang Li, Weiliang Zhu, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2015, 43 (10) 1632-1641; DOI: https://doi.org/10.1124/dmd.115.064949
  8. Liu, Xin

    1. Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1<em>α</em>, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      You have access
      Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1α, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      Linfeng Dong, Qingmei Chen, Xin Liu, Jikai Wen, Jun Jiang and Yiqun Deng
      Drug Metabolism and Disposition October 2015, 43 (10) 1458-1467; DOI: https://doi.org/10.1124/dmd.115.065565
  9. Lu, Danyi

    1. You have access
      Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Controls Efflux Transport of Hesperetin Sulfates in Sulfotransferase 1A3–Overexpressing Human Embryonic Kidney 293 Cells
      Hua Sun, Xiao Wang, Xiaotong Zhou, Danyi Lu, Zhiguo Ma and Baojian Wu
      Drug Metabolism and Disposition October 2015, 43 (10) 1430-1440; DOI: https://doi.org/10.1124/dmd.115.065953

M

  1. Ma, Yi Hua

    1. Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      You have access
      Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      Jing Zhou, Yi Hua Ma, Zhong Zhou, Yan Chen, Ying Wang and Xia Gao
      Drug Metabolism and Disposition October 2015, 43 (10) 1590-1600; DOI: https://doi.org/10.1124/dmd.115.064386
  2. Ma, Zhiguo

    1. You have access
      Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Controls Efflux Transport of Hesperetin Sulfates in Sulfotransferase 1A3–Overexpressing Human Embryonic Kidney 293 Cells
      Hua Sun, Xiao Wang, Xiaotong Zhou, Danyi Lu, Zhiguo Ma and Baojian Wu
      Drug Metabolism and Disposition October 2015, 43 (10) 1430-1440; DOI: https://doi.org/10.1124/dmd.115.065953
  3. Mansell, Sara E.

    1. You have access
      CYP3A Activity and Expression in Nonalcoholic Fatty Liver Disease
      Sarah J. Woolsey, Sara E. Mansell, Richard B. Kim, Rommel G. Tirona and Melanie D. Beaton
      Drug Metabolism and Disposition October 2015, 43 (10) 1484-1490; DOI: https://doi.org/10.1124/dmd.115.065979
  4. Mao, Xu

    1. You have access
      In Vitro and In Vivo Characterization of Reactive Intermediates of Corynoline
      Xu Mao, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition October 2015, 43 (10) 1491-1498; DOI: https://doi.org/10.1124/dmd.115.065813
  5. Martin, Jennifer A.

    1. You have access
      Disposition of Basal Insulin Peglispro Compared with 20-kDa Polyethylene Glycol in Rats Following a Single Intravenous or Subcutaneous Dose
      Mary Pat Knadler, Bernice B. Ellis, Patricia L. Brown-Augsburger, Anthony T. Murphy, Jennifer A. Martin and Victor J. Wroblewski
      Drug Metabolism and Disposition October 2015, 43 (10) 1477-1483; DOI: https://doi.org/10.1124/dmd.115.064337
  6. McCabe, Michelle

    1. You have access
      Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies
      Michelle McCabe, Rucha S. Sane, Monica Keith-Luzzi, Jun Xu, Illeaniz King, Andrea Whitcher-Johnstone, Nicholas Johnstone, Donald J. Tweedie and Yongmei Li
      Drug Metabolism and Disposition October 2015, 43 (10) 1612-1618; DOI: https://doi.org/10.1124/dmd.115.064477
  7. McLeod, Howard L.

    1. You have access
      Single-Nucleotide Polymorphisms in Cytochrome P450 2E1 (CYP2E1) 3′-Untranslated Region Affect the Regulation of CYP2E1 by miR-570
      Masataka Nakano, Takuya Mohri, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Howard L. McLeod and Miki Nakajima
      Drug Metabolism and Disposition October 2015, 43 (10) 1450-1457; DOI: https://doi.org/10.1124/dmd.115.065664
  8. Miners, John O.

    1. You have access
      Inhibition of Human UDP-Glucuronosyltransferase Enzymes by Canagliflozin and Dapagliflozin: Implications for Drug-Drug Interactions
      Attarat Pattanawongsa, Nuy Chau, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition October 2015, 43 (10) 1468-1476; DOI: https://doi.org/10.1124/dmd.115.065870
  9. Mohri, Takuya

    1. You have access
      Single-Nucleotide Polymorphisms in Cytochrome P450 2E1 (CYP2E1) 3′-Untranslated Region Affect the Regulation of CYP2E1 by miR-570
      Masataka Nakano, Takuya Mohri, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Howard L. McLeod and Miki Nakajima
      Drug Metabolism and Disposition October 2015, 43 (10) 1450-1457; DOI: https://doi.org/10.1124/dmd.115.065664
  10. Murphy, Anthony T.

    1. You have access
      Disposition of Basal Insulin Peglispro Compared with 20-kDa Polyethylene Glycol in Rats Following a Single Intravenous or Subcutaneous Dose
      Mary Pat Knadler, Bernice B. Ellis, Patricia L. Brown-Augsburger, Anthony T. Murphy, Jennifer A. Martin and Victor J. Wroblewski
      Drug Metabolism and Disposition October 2015, 43 (10) 1477-1483; DOI: https://doi.org/10.1124/dmd.115.064337
  11. Murray, Iain A.

    1. You have access
      Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation
      Troy D. Hubbard, Iain A. Murray and Gary H. Perdew
      Drug Metabolism and Disposition October 2015, 43 (10) 1522-1535; DOI: https://doi.org/10.1124/dmd.115.064246

N

  1. Nakajima, Miki

    1. You have access
      Single-Nucleotide Polymorphisms in Cytochrome P450 2E1 (CYP2E1) 3′-Untranslated Region Affect the Regulation of CYP2E1 by miR-570
      Masataka Nakano, Takuya Mohri, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Howard L. McLeod and Miki Nakajima
      Drug Metabolism and Disposition October 2015, 43 (10) 1450-1457; DOI: https://doi.org/10.1124/dmd.115.065664
  2. Nakano, Masataka

    1. You have access
      Single-Nucleotide Polymorphisms in Cytochrome P450 2E1 (CYP2E1) 3′-Untranslated Region Affect the Regulation of CYP2E1 by miR-570
      Masataka Nakano, Takuya Mohri, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Howard L. McLeod and Miki Nakajima
      Drug Metabolism and Disposition October 2015, 43 (10) 1450-1457; DOI: https://doi.org/10.1124/dmd.115.065664

P

  1. Pattanawongsa, Attarat

    1. You have access
      Inhibition of Human UDP-Glucuronosyltransferase Enzymes by Canagliflozin and Dapagliflozin: Implications for Drug-Drug Interactions
      Attarat Pattanawongsa, Nuy Chau, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition October 2015, 43 (10) 1468-1476; DOI: https://doi.org/10.1124/dmd.115.065870
  2. Peng, Ying

    1. You have access
      In Vitro and In Vivo Characterization of Reactive Intermediates of Corynoline
      Xu Mao, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition October 2015, 43 (10) 1491-1498; DOI: https://doi.org/10.1124/dmd.115.065813
  3. Perdew, Gary H.

    1. You have access
      Indole and Tryptophan Metabolism: Endogenous and Dietary Routes to Ah Receptor Activation
      Troy D. Hubbard, Iain A. Murray and Gary H. Perdew
      Drug Metabolism and Disposition October 2015, 43 (10) 1522-1535; DOI: https://doi.org/10.1124/dmd.115.064246

R

  1. Rosenfeld, Cheryl S.

    1. You have access
      Microbiome Disturbances and Autism Spectrum Disorders
      Cheryl S. Rosenfeld
      Drug Metabolism and Disposition October 2015, 43 (10) 1557-1571; DOI: https://doi.org/10.1124/dmd.115.063826
  2. Rowland, Andrew

    1. You have access
      Inhibition of Human UDP-Glucuronosyltransferase Enzymes by Canagliflozin and Dapagliflozin: Implications for Drug-Drug Interactions
      Attarat Pattanawongsa, Nuy Chau, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition October 2015, 43 (10) 1468-1476; DOI: https://doi.org/10.1124/dmd.115.065870
  3. Ruan, Jian-Qing

    1. You have access
      The Presystemic Interplay between Gut Microbiota and Orally Administered Calycosin-7-O-β-d-Glucoside
      Jian-Qing Ruan, Shang Li, Ya-Ping Li, Wen-Jin Wu, Simon Ming-Yuen Lee and Ru Yan
      Drug Metabolism and Disposition October 2015, 43 (10) 1601-1611; DOI: https://doi.org/10.1124/dmd.115.065094

S

  1. Safe, Stephen

    1. You have access
      Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes
      Yating Cheng, Un-Ho Jin, Clint D. Allred, Arul Jayaraman, Robert S. Chapkin and Stephen Safe
      Drug Metabolism and Disposition October 2015, 43 (10) 1536-1543; DOI: https://doi.org/10.1124/dmd.115.063677
  2. Sane, Rucha S.

    1. You have access
      Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies
      Michelle McCabe, Rucha S. Sane, Monica Keith-Luzzi, Jun Xu, Illeaniz King, Andrea Whitcher-Johnstone, Nicholas Johnstone, Donald J. Tweedie and Yongmei Li
      Drug Metabolism and Disposition October 2015, 43 (10) 1612-1618; DOI: https://doi.org/10.1124/dmd.115.064477
  3. Sasaki, Erika

    1. Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, <em>S</em>-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      You have access
      Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition October 2015, 43 (10) 1408-1416; DOI: https://doi.org/10.1124/dmd.115.066100
  4. Selwyn, Felcy Pavithra

    1. You have access
      RNA-Seq Quantification of Hepatic Drug Processing Genes in Germ-Free Mice
      Felcy Pavithra Selwyn, Julia Yue Cui and Curtis D. Klaassen
      Drug Metabolism and Disposition October 2015, 43 (10) 1572-1580; DOI: https://doi.org/10.1124/dmd.115.063545
    2. You have access
      Importance of Large Intestine in Regulating Bile Acids and Glucagon-Like Peptide-1 in Germ-Free Mice
      Felcy Pavithra Selwyn, Iván L. Csanaky, Youcai Zhang and Curtis D. Klaassen
      Drug Metabolism and Disposition October 2015, 43 (10) 1544-1556; DOI: https://doi.org/10.1124/dmd.115.065276
  5. Shimizu, Makiko

    1. Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, <em>S</em>-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      You have access
      Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition October 2015, 43 (10) 1408-1416; DOI: https://doi.org/10.1124/dmd.115.066100
  6. Smith, Bill J.

    1. Prediction of Drug-Drug Interactions with Crizotinib as the CYP3A Substrate Using a Physiologically Based Pharmacokinetic Model
      You have access
      Prediction of Drug-Drug Interactions with Crizotinib as the CYP3A Substrate Using a Physiologically Based Pharmacokinetic Model
      Shinji Yamazaki, Theodore R. Johnson and Bill J. Smith
      Drug Metabolism and Disposition October 2015, 43 (10) 1417-1429; DOI: https://doi.org/10.1124/dmd.115.064618
  7. Sun, Hua

    1. You have access
      Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Controls Efflux Transport of Hesperetin Sulfates in Sulfotransferase 1A3–Overexpressing Human Embryonic Kidney 293 Cells
      Hua Sun, Xiao Wang, Xiaotong Zhou, Danyi Lu, Zhiguo Ma and Baojian Wu
      Drug Metabolism and Disposition October 2015, 43 (10) 1430-1440; DOI: https://doi.org/10.1124/dmd.115.065953
  8. Svensson, Per H.

    1. Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      You have access
      Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      Chungang Gu, Richard J. Lewis, Andrew S. Wells, Per H. Svensson, Vinayak P. Hosagrahara, Eskil Johnsson and Gösta Hallström
      Drug Metabolism and Disposition October 2015, 43 (10) 1441-1449; DOI: https://doi.org/10.1124/dmd.115.065136
  9. Swanson, Hollie I.

    1. You have access
      Drug Metabolism by the Host and Gut Microbiota: A Partnership or Rivalry?
      Hollie I. Swanson
      Drug Metabolism and Disposition October 2015, 43 (10) 1499-1504; DOI: https://doi.org/10.1124/dmd.115.065714

T

  1. Takamiya, Masataka

    1. You have access
      Single-Nucleotide Polymorphisms in Cytochrome P450 2E1 (CYP2E1) 3′-Untranslated Region Affect the Regulation of CYP2E1 by miR-570
      Masataka Nakano, Takuya Mohri, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Howard L. McLeod and Miki Nakajima
      Drug Metabolism and Disposition October 2015, 43 (10) 1450-1457; DOI: https://doi.org/10.1124/dmd.115.065664
  2. Tirona, Rommel G.

    1. You have access
      CYP3A Activity and Expression in Nonalcoholic Fatty Liver Disease
      Sarah J. Woolsey, Sara E. Mansell, Richard B. Kim, Rommel G. Tirona and Melanie D. Beaton
      Drug Metabolism and Disposition October 2015, 43 (10) 1484-1490; DOI: https://doi.org/10.1124/dmd.115.065979
  3. Toda, Akiko

    1. Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, <em>S</em>-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      You have access
      Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition October 2015, 43 (10) 1408-1416; DOI: https://doi.org/10.1124/dmd.115.066100
  4. Tweedie, Donald J.

    1. You have access
      Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies
      Michelle McCabe, Rucha S. Sane, Monica Keith-Luzzi, Jun Xu, Illeaniz King, Andrea Whitcher-Johnstone, Nicholas Johnstone, Donald J. Tweedie and Yongmei Li
      Drug Metabolism and Disposition October 2015, 43 (10) 1612-1618; DOI: https://doi.org/10.1124/dmd.115.064477

U

  1. Uehara, Shotaro

    1. Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, <em>S</em>-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      You have access
      Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition October 2015, 43 (10) 1408-1416; DOI: https://doi.org/10.1124/dmd.115.066100
  2. Uno, Yasuhiro

    1. Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, <em>S</em>-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      You have access
      Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition October 2015, 43 (10) 1408-1416; DOI: https://doi.org/10.1124/dmd.115.066100
  3. Utoh, Masahiro

    1. Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, <em>S</em>-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      You have access
      Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition October 2015, 43 (10) 1408-1416; DOI: https://doi.org/10.1124/dmd.115.066100

W

  1. Wang, Xiao

    1. You have access
      Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Controls Efflux Transport of Hesperetin Sulfates in Sulfotransferase 1A3–Overexpressing Human Embryonic Kidney 293 Cells
      Hua Sun, Xiao Wang, Xiaotong Zhou, Danyi Lu, Zhiguo Ma and Baojian Wu
      Drug Metabolism and Disposition October 2015, 43 (10) 1430-1440; DOI: https://doi.org/10.1124/dmd.115.065953
  2. Wang, Ying

    1. Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      You have access
      Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      Jing Zhou, Yi Hua Ma, Zhong Zhou, Yan Chen, Ying Wang and Xia Gao
      Drug Metabolism and Disposition October 2015, 43 (10) 1590-1600; DOI: https://doi.org/10.1124/dmd.115.064386
  3. Wells, Andrew S.

    1. Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      You have access
      Lipid Peroxide–Mediated Oxidative Rearrangement of the Pyrazinone Carboxamide Core of Neutrophil Elastase Inhibitor AZD9819 in Blood Plasma Samples
      Chungang Gu, Richard J. Lewis, Andrew S. Wells, Per H. Svensson, Vinayak P. Hosagrahara, Eskil Johnsson and Gösta Hallström
      Drug Metabolism and Disposition October 2015, 43 (10) 1441-1449; DOI: https://doi.org/10.1124/dmd.115.065136
  4. Wen, Jikai

    1. Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1<em>α</em>, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      You have access
      Role of Specificity Protein 1, Hepatocyte Nuclear Factor 1α, and Pregnane X Receptor in the Basal and Rifampicin-Induced Transcriptional Regulation of Porcine Cytochrome P450 3A46
      Linfeng Dong, Qingmei Chen, Xin Liu, Jikai Wen, Jun Jiang and Yiqun Deng
      Drug Metabolism and Disposition October 2015, 43 (10) 1458-1467; DOI: https://doi.org/10.1124/dmd.115.065565
  5. Whitcher-Johnstone, Andrea

    1. You have access
      Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies
      Michelle McCabe, Rucha S. Sane, Monica Keith-Luzzi, Jun Xu, Illeaniz King, Andrea Whitcher-Johnstone, Nicholas Johnstone, Donald J. Tweedie and Yongmei Li
      Drug Metabolism and Disposition October 2015, 43 (10) 1612-1618; DOI: https://doi.org/10.1124/dmd.115.064477
  6. Woolsey, Sarah J.

    1. You have access
      CYP3A Activity and Expression in Nonalcoholic Fatty Liver Disease
      Sarah J. Woolsey, Sara E. Mansell, Richard B. Kim, Rommel G. Tirona and Melanie D. Beaton
      Drug Metabolism and Disposition October 2015, 43 (10) 1484-1490; DOI: https://doi.org/10.1124/dmd.115.065979
  7. Wright, Stephen H.

    1. Making Transporter Models for Drug–Drug Interaction Prediction Mobile
      You have access
      Making Transporter Models for Drug–Drug Interaction Prediction Mobile
      Sean Ekins, Alex M. Clark and Stephen H. Wright
      Drug Metabolism and Disposition October 2015, 43 (10) 1642-1645; DOI: https://doi.org/10.1124/dmd.115.064956
  8. Wroblewski, Victor J.

    1. You have access
      Disposition of Basal Insulin Peglispro Compared with 20-kDa Polyethylene Glycol in Rats Following a Single Intravenous or Subcutaneous Dose
      Mary Pat Knadler, Bernice B. Ellis, Patricia L. Brown-Augsburger, Anthony T. Murphy, Jennifer A. Martin and Victor J. Wroblewski
      Drug Metabolism and Disposition October 2015, 43 (10) 1477-1483; DOI: https://doi.org/10.1124/dmd.115.064337
  9. Wu, Baojian

    1. You have access
      Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Controls Efflux Transport of Hesperetin Sulfates in Sulfotransferase 1A3–Overexpressing Human Embryonic Kidney 293 Cells
      Hua Sun, Xiao Wang, Xiaotong Zhou, Danyi Lu, Zhiguo Ma and Baojian Wu
      Drug Metabolism and Disposition October 2015, 43 (10) 1430-1440; DOI: https://doi.org/10.1124/dmd.115.065953
  10. Wu, Wen-Jin

    1. You have access
      The Presystemic Interplay between Gut Microbiota and Orally Administered Calycosin-7-O-β-d-Glucoside
      Jian-Qing Ruan, Shang Li, Ya-Ping Li, Wen-Jin Wu, Simon Ming-Yuen Lee and Ru Yan
      Drug Metabolism and Disposition October 2015, 43 (10) 1601-1611; DOI: https://doi.org/10.1124/dmd.115.065094

X

  1. Xu, Jun

    1. You have access
      Defining the Role of Gut Bacteria in the Metabolism of Deleobuvir: In Vitro and In Vivo Studies
      Michelle McCabe, Rucha S. Sane, Monica Keith-Luzzi, Jun Xu, Illeaniz King, Andrea Whitcher-Johnstone, Nicholas Johnstone, Donald J. Tweedie and Yongmei Li
      Drug Metabolism and Disposition October 2015, 43 (10) 1612-1618; DOI: https://doi.org/10.1124/dmd.115.064477

Y

  1. Yamazaki, Hiroshi

    1. Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, <em>S</em>-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      You have access
      Novel Marmoset Cytochrome P450 2C19 in Livers Efficiently Metabolizes Human P450 2C9 and 2C19 Substrates, S-Warfarin, Tolbutamide, Flurbiprofen, and Omeprazole
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Mirai Kawano, Makiko Shimizu, Akiko Toda, Masahiro Utoh, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition October 2015, 43 (10) 1408-1416; DOI: https://doi.org/10.1124/dmd.115.066100
  2. Yamazaki, Shinji

    1. Prediction of Drug-Drug Interactions with Crizotinib as the CYP3A Substrate Using a Physiologically Based Pharmacokinetic Model
      You have access
      Prediction of Drug-Drug Interactions with Crizotinib as the CYP3A Substrate Using a Physiologically Based Pharmacokinetic Model
      Shinji Yamazaki, Theodore R. Johnson and Bill J. Smith
      Drug Metabolism and Disposition October 2015, 43 (10) 1417-1429; DOI: https://doi.org/10.1124/dmd.115.064618
  3. Yan, Ru

    1. You have access
      The Presystemic Interplay between Gut Microbiota and Orally Administered Calycosin-7-O-β-d-Glucoside
      Jian-Qing Ruan, Shang Li, Ya-Ping Li, Wen-Jin Wu, Simon Ming-Yuen Lee and Ru Yan
      Drug Metabolism and Disposition October 2015, 43 (10) 1601-1611; DOI: https://doi.org/10.1124/dmd.115.065094
  4. Yip, Lian Yee

    1. You have access
      Investigation of Host–Gut Microbiota Modulation of Therapeutic Outcome
      Lian Yee Yip and Eric Chun Yong Chan
      Drug Metabolism and Disposition October 2015, 43 (10) 1619-1631; DOI: https://doi.org/10.1124/dmd.115.063750

Z

  1. Zhang, Youcai

    1. You have access
      Importance of Large Intestine in Regulating Bile Acids and Glucagon-Like Peptide-1 in Germ-Free Mice
      Felcy Pavithra Selwyn, Iván L. Csanaky, Youcai Zhang and Curtis D. Klaassen
      Drug Metabolism and Disposition October 2015, 43 (10) 1544-1556; DOI: https://doi.org/10.1124/dmd.115.065276
  2. Zheng, Jiang

    1. You have access
      In Vitro and In Vivo Characterization of Reactive Intermediates of Corynoline
      Xu Mao, Ying Peng and Jiang Zheng
      Drug Metabolism and Disposition October 2015, 43 (10) 1491-1498; DOI: https://doi.org/10.1124/dmd.115.065813
  3. Zhong, Dafang

    1. You have access
      Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel
      Cai Liu, Zhaoqiang Chen, Kan Zhong, Liang Li, Weiliang Zhu, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2015, 43 (10) 1632-1641; DOI: https://doi.org/10.1124/dmd.115.064949
  4. Zhong, Kan

    1. You have access
      Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel
      Cai Liu, Zhaoqiang Chen, Kan Zhong, Liang Li, Weiliang Zhu, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2015, 43 (10) 1632-1641; DOI: https://doi.org/10.1124/dmd.115.064949
  5. Zhou, Jing

    1. Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      You have access
      Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      Jing Zhou, Yi Hua Ma, Zhong Zhou, Yan Chen, Ying Wang and Xia Gao
      Drug Metabolism and Disposition October 2015, 43 (10) 1590-1600; DOI: https://doi.org/10.1124/dmd.115.064386
  6. Zhou, Xiaotong

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      Multidrug Resistance-Associated Protein 4 (MRP4/ABCC4) Controls Efflux Transport of Hesperetin Sulfates in Sulfotransferase 1A3–Overexpressing Human Embryonic Kidney 293 Cells
      Hua Sun, Xiao Wang, Xiaotong Zhou, Danyi Lu, Zhiguo Ma and Baojian Wu
      Drug Metabolism and Disposition October 2015, 43 (10) 1430-1440; DOI: https://doi.org/10.1124/dmd.115.065953
  7. Zhou, Zhong

    1. Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      You have access
      Intestinal Absorption and Metabolism of Epimedium Flavonoids in Osteoporosis Rats
      Jing Zhou, Yi Hua Ma, Zhong Zhou, Yan Chen, Ying Wang and Xia Gao
      Drug Metabolism and Disposition October 2015, 43 (10) 1590-1600; DOI: https://doi.org/10.1124/dmd.115.064386
  8. Zhu, Weiliang

    1. You have access
      Human Liver Cytochrome P450 Enzymes and Microsomal Thiol Methyltransferase Are Involved in the Stereoselective Formation and Methylation of the Pharmacologically Active Metabolite of Clopidogrel
      Cai Liu, Zhaoqiang Chen, Kan Zhong, Liang Li, Weiliang Zhu, Xiaoyan Chen and Dafang Zhong
      Drug Metabolism and Disposition October 2015, 43 (10) 1632-1641; DOI: https://doi.org/10.1124/dmd.115.064949
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Drug Metabolism and Disposition: 43 (10)
Drug Metabolism and Disposition
Vol. 43, Issue 10
1 Oct 2015
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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