Inhibition of Human UDP-Glucuronosyltransferase Enzymes by Canagliflozin and Dapagliflozin: Implications for Drug-Drug Interactions

Attarat Pattanawongsa; Nuy Chau; Andrew Rowland; John O. Miners

doi:10.1124/dmd.115.065870

Research ArticleArticle

Inhibition of Human UDP-Glucuronosyltransferase Enzymes by Canagliflozin and Dapagliflozin: Implications for Drug-Drug Interactions

Attarat Pattanawongsa, Nuy Chau, Andrew Rowland and John O. Miners

Drug Metabolism and Disposition October 2015, 43 (10) 1468-1476; DOI: https://doi.org/10.1124/dmd.115.065870

Attarat Pattanawongsa

Department of Clinical Pharmacology (A.P., N.C., A.R., J.O.M.) and Flinders Centre for Innovation in Cancer, Flinders University School of Medicine, Adelaide, Australia (A.R., J.O.M.)

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Nuy Chau

Department of Clinical Pharmacology (A.P., N.C., A.R., J.O.M.) and Flinders Centre for Innovation in Cancer, Flinders University School of Medicine, Adelaide, Australia (A.R., J.O.M.)

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Andrew Rowland

Department of Clinical Pharmacology (A.P., N.C., A.R., J.O.M.) and Flinders Centre for Innovation in Cancer, Flinders University School of Medicine, Adelaide, Australia (A.R., J.O.M.)

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John O. Miners

Department of Clinical Pharmacology (A.P., N.C., A.R., J.O.M.) and Flinders Centre for Innovation in Cancer, Flinders University School of Medicine, Adelaide, Australia (A.R., J.O.M.)

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Drug Metabolism and Disposition

Vol. 43, Issue 10

1 Oct 2015

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Research ArticleArticle

UGT Enzyme Inhibition by Canagliflozin and Dapagliflozin

Attarat Pattanawongsa, Nuy Chau, Andrew Rowland and John O. Miners

Drug Metabolism and Disposition October 1, 2015, 43 (10) 1468-1476; DOI: https://doi.org/10.1124/dmd.115.065870

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Research ArticleArticle

UGT Enzyme Inhibition by Canagliflozin and Dapagliflozin

Attarat Pattanawongsa, Nuy Chau, Andrew Rowland and John O. Miners

Drug Metabolism and Disposition October 1, 2015, 43 (10) 1468-1476; DOI: https://doi.org/10.1124/dmd.115.065870

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