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Research ArticleSpecial Section on Drug Metabolism and the Microbiome

Aryl Hydrocarbon Receptor Activity of Tryptophan Metabolites in Young Adult Mouse Colonocytes

Yating Cheng, Un-Ho Jin, Clint D. Allred, Arul Jayaraman, Robert S. Chapkin and Stephen Safe
Drug Metabolism and Disposition October 2015, 43 (10) 1536-1543; DOI: https://doi.org/10.1124/dmd.115.063677
Yating Cheng
Department of Veterinary Physiology and Pharmacology (Y.C., U.-H.J., S.S.), Department of Nutrition and Food Science (C.D.A., R.S.C.), Department of Chemical Engineering (A.J.), Texas A&M University, College Station, Texas
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Un-Ho Jin
Department of Veterinary Physiology and Pharmacology (Y.C., U.-H.J., S.S.), Department of Nutrition and Food Science (C.D.A., R.S.C.), Department of Chemical Engineering (A.J.), Texas A&M University, College Station, Texas
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Clint D. Allred
Department of Veterinary Physiology and Pharmacology (Y.C., U.-H.J., S.S.), Department of Nutrition and Food Science (C.D.A., R.S.C.), Department of Chemical Engineering (A.J.), Texas A&M University, College Station, Texas
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Arul Jayaraman
Department of Veterinary Physiology and Pharmacology (Y.C., U.-H.J., S.S.), Department of Nutrition and Food Science (C.D.A., R.S.C.), Department of Chemical Engineering (A.J.), Texas A&M University, College Station, Texas
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Robert S. Chapkin
Department of Veterinary Physiology and Pharmacology (Y.C., U.-H.J., S.S.), Department of Nutrition and Food Science (C.D.A., R.S.C.), Department of Chemical Engineering (A.J.), Texas A&M University, College Station, Texas
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Stephen Safe
Department of Veterinary Physiology and Pharmacology (Y.C., U.-H.J., S.S.), Department of Nutrition and Food Science (C.D.A., R.S.C.), Department of Chemical Engineering (A.J.), Texas A&M University, College Station, Texas
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Article Information

vol. 43 no. 10 1536-1543
DOI 
https://doi.org/10.1124/dmd.115.063677
PubMed 
25873348

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 15, 2014
  • Accepted January 1, 2015
  • Published online September 1, 2015.

Article Versions

  • Earlier version (April 14, 2015 - 08:04).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Yating Cheng,
  2. Un-Ho Jin,
  3. Clint D. Allred,
  4. Arul Jayaraman,
  5. Robert S. Chapkin, and
  6. Stephen Safe
  1. Department of Veterinary Physiology and Pharmacology (Y.C., U.-H.J., S.S.), Department of Nutrition and Food Science (C.D.A., R.S.C.), Department of Chemical Engineering (A.J.), Texas A&M University, College Station, Texas
  1. Address correspondence to:
    Stephen H. Safe, Department of Veterinary Physiology and Pharmacology, Texas A&M University, 4466 TAMU, College Station, TX 77843-4466. E-mail: ssafe{at}cvm.tamu.edu
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Drug Metabolism and Disposition: 43 (10)
Drug Metabolism and Disposition
Vol. 43, Issue 10
1 Oct 2015
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Research ArticleSpecial Section on Drug Metabolism and the Microbiome

Tryptophan Metabolites Are Selective AhR Modulators

Yating Cheng, Un-Ho Jin, Clint D. Allred, Arul Jayaraman, Robert S. Chapkin and Stephen Safe
Drug Metabolism and Disposition October 1, 2015, 43 (10) 1536-1543; DOI: https://doi.org/10.1124/dmd.115.063677

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Research ArticleSpecial Section on Drug Metabolism and the Microbiome

Tryptophan Metabolites Are Selective AhR Modulators

Yating Cheng, Un-Ho Jin, Clint D. Allred, Arul Jayaraman, Robert S. Chapkin and Stephen Safe
Drug Metabolism and Disposition October 1, 2015, 43 (10) 1536-1543; DOI: https://doi.org/10.1124/dmd.115.063677
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