Index by author
November 01, 2015; Volume 43,Issue 11
A
Au, Nicholas T.
- You have accessP450-Based Drug-Drug Interactions of Amiodarone and its Metabolites: Diversity of Inhibitory MechanismsMatthew G. McDonald, Nicholas T. Au and Allan E. RettieDrug Metabolism and Disposition November 2015, 43 (11) 1661-1669; DOI: https://doi.org/10.1124/dmd.115.065623
B
Backman, Janne T.
- You have accessClopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate SimvastatinMatti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. BackmanDrug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938
Blobaum, Anna L.
- You have accessA Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In VivoAnna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott DanielsDrug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006
Braeuning, Albert
- You have accessApplication of HC-AFW1 Hepatocarcinoma Cells for Mechanistic Studies: Regulation of Cytochrome P450 2B6 Expression by Dimethyl Sulfoxide and Early Growth Response 1Barbara Petzuch, Nicola Groll, Michael Schwarz and Albert BraeuningDrug Metabolism and Disposition November 2015, 43 (11) 1727-1733; DOI: https://doi.org/10.1124/dmd.115.064659
- You have accessComparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor AgonistsAlbert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael SchwarzDrug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Bridges, Thomas M.
- You have accessA Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In VivoAnna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott DanielsDrug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006
Buckley, David B.
- You have accessThe Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 ExperimentsLois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew ParkinsonDrug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
Busch, Diana
- You have accessDefining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse ModelNico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland WolfDrug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656
Byers, Frank W.
- You have accessA Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In VivoAnna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott DanielsDrug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006
C
Cai, Hong
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Chaudhry, Amarjit
- You have accessIn Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter MiceKazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. SchuetzDrug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078
Chen, Xiaoyan
- You have accessFasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver InjuryXiuli Li, Kan Zhong, Zitao Guo, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition November 2015, 43 (11) 1751-1759; DOI: https://doi.org/10.1124/dmd.115.064121
Chen, Yang
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
Cline, Cynthia
- You have accessIn Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter MiceKazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. SchuetzDrug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078
Collier, Ann C.
- You have accessModulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging StudyLi Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. UnadkatDrug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
Conn, P. Jeffrey
- You have accessA Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In VivoAnna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott DanielsDrug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006
D
Daniels, J. Scott
- You have accessA Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In VivoAnna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott DanielsDrug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006
Deo, Anand K.
- You have accessModulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging StudyLi Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. UnadkatDrug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
Dierks, Elizabeth A.
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Domino, Karen B.
- You have accessModulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging StudyLi Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. UnadkatDrug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
Duan, Haichuan
- You have accessPotent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease InhibitorsHaichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne WangDrug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824
E
Eary, Janet F.
- You have accessModulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging StudyLi Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. UnadkatDrug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
F
Finel, Moshe
- You have accessThe Polymorphic Variant P24T of UDP-Glucuronosyltransferase 1A4 and Its Unusual ConsequencesJohanna Troberg and Moshe FinelDrug Metabolism and Disposition November 2015, 43 (11) 1769-1772; DOI: https://doi.org/10.1124/dmd.115.065680
Foti, Robert S.
- You have accessPotent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease InhibitorsHaichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne WangDrug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824
Fox, Maxine
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
G
Ganguly, Samit
- You have accessIn Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter MiceKazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. SchuetzDrug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078
Graf, Tyler N.
- You have accessChemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan GlucuronidesBrandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition November 2015, 43 (11) 1734-1743; DOI: https://doi.org/10.1124/dmd.115.066076
Groll, Nicola
- You have accessApplication of HC-AFW1 Hepatocarcinoma Cells for Mechanistic Studies: Regulation of Cytochrome P450 2B6 Expression by Dimethyl Sulfoxide and Early Growth Response 1Barbara Petzuch, Nicola Groll, Michael Schwarz and Albert BraeuningDrug Metabolism and Disposition November 2015, 43 (11) 1727-1733; DOI: https://doi.org/10.1124/dmd.115.064659
Gu, Xiaomei
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Gufford, Brandon T.
- You have accessChemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan GlucuronidesBrandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition November 2015, 43 (11) 1734-1743; DOI: https://doi.org/10.1124/dmd.115.066076
Guo, Haifang
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
Guo, Zitao
- You have accessFasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver InjuryXiuli Li, Kan Zhong, Zitao Guo, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition November 2015, 43 (11) 1751-1759; DOI: https://doi.org/10.1124/dmd.115.064121
H
Haupt, Lois J.
- You have accessThe Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 ExperimentsLois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew ParkinsonDrug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
Henderson, Colin. J.
- You have accessDefining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse ModelNico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland WolfDrug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656
Hofmann, Ute
- You have accessComparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor AgonistsAlbert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael SchwarzDrug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Hsiao, Peng
- You have accessModulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging StudyLi Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. UnadkatDrug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
Hu, Mengyue
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
Hu, Tao
- You have accessPotent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease InhibitorsHaichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne WangDrug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824
Huang, Ke
- You have accessHigh-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical InteractionsGuannan Li, Ke Huang, Dejan Nikolic and Richard B. van BreemenDrug Metabolism and Disposition November 2015, 43 (11) 1670-1678; DOI: https://doi.org/10.1124/dmd.115.065987
Humphreys, W. Griffith
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
I
Isoherranen, Nina
- You have accessPhysiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model VerificationJennifer E. Sager, Jingjing Yu, Isabelle Ragueneau-Majlessi and Nina IsoherranenDrug Metabolism and Disposition November 2015, 43 (11) 1823-1837; DOI: https://doi.org/10.1124/dmd.115.065920
Itkonen, Matti K.
- You have accessClopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate SimvastatinMatti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. BackmanDrug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938
Ito, Kousei
- You have accessPrediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte AssayTakeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei ItoDrug Metabolism and Disposition November 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425
J
Johänning, Janina
- You have accessComparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor AgonistsAlbert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael SchwarzDrug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Jones, Russell
- You have accessA New Rapid In Vitro Assay for Assessing Reactivity of Acyl GlucuronidesSheng Zhong, Russell Jones, Wenzhe Lu, Simone Schadt and Giorgio OttavianiDrug Metabolism and Disposition November 2015, 43 (11) 1711-1717; DOI: https://doi.org/10.1124/dmd.115.066159
K
Kapelyukh, Yury
- You have accessDefining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse ModelNico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland WolfDrug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656
Kato, Masashi
- You have accessNew Photosafety Assessment Strategy Based on the Photochemical and Pharmacokinetic Properties of Both Parent Chemicals and MetabolitesMasashi Kato, Gen Suzuki, Hiroto Ohtake, Yoshiki Seto and Satomi OnoueDrug Metabolism and Disposition November 2015, 43 (11) 1815-1822; DOI: https://doi.org/10.1124/dmd.115.065060
Kazmi, Faraz
- You have accessThe Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 ExperimentsLois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew ParkinsonDrug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
Kim, Richard B.
- You have accessIn Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter MiceKazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. SchuetzDrug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078
Korprasertthaworn, Porntipa
- You have accessIn Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine MetabolismPorntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew RowlandDrug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790
L
Lai, Yurong
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Leatherman, Sarah
- You have accessThe Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 ExperimentsLois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew ParkinsonDrug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
Li, Feng
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
Li, Guannan
- You have accessHigh-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical InteractionsGuannan Li, Ke Huang, Dejan Nikolic and Richard B. van BreemenDrug Metabolism and Disposition November 2015, 43 (11) 1670-1678; DOI: https://doi.org/10.1124/dmd.115.065987
Li, Jia
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
Li, Xiuli
- You have accessFasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver InjuryXiuli Li, Kan Zhong, Zitao Guo, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition November 2015, 43 (11) 1751-1759; DOI: https://doi.org/10.1124/dmd.115.064121
Li, Ying
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
Lin, De
- You have accessDefining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse ModelNico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland WolfDrug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656
Lin, Yvonne S.
- You have accessIn Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter MiceKazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. SchuetzDrug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078
Lindsley, Craig W.
- You have accessA Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In VivoAnna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott DanielsDrug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006
Link, Jeanne M.
- You have accessModulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging StudyLi Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. UnadkatDrug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
Liu, Can
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
Liu, Li
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
- You have accessModulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging StudyLi Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. UnadkatDrug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
Liu, Xiaodong
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
Locuson, Charles W.
- You have accessA Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In VivoAnna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott DanielsDrug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006
Lu, Wenzhe
- You have accessA New Rapid In Vitro Assay for Assessing Reactivity of Acyl GlucuronidesSheng Zhong, Russell Jones, Wenzhe Lu, Simone Schadt and Giorgio OttavianiDrug Metabolism and Disposition November 2015, 43 (11) 1711-1717; DOI: https://doi.org/10.1124/dmd.115.066159
Luk, Chiuwa E.
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
M
MacGuire, Jamus G.
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Mankoff, David A.
- You have accessModulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging StudyLi Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. UnadkatDrug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
Marathe, Punit
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Martorana, Giuseppe Ettore
- You have accessInhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising DrugsAlvaro Mordente, Andrea Silvestrini, Giuseppe Ettore Martorana, Daniela Tavian and Elisabetta MeucciDrug Metabolism and Disposition November 2015, 43 (11) 1691-1701; DOI: https://doi.org/10.1124/dmd.115.065110
McDonald, Matthew G.
- You have accessP450-Based Drug-Drug Interactions of Amiodarone and its Metabolites: Diversity of Inhibitory MechanismsMatthew G. McDonald, Nicholas T. Au and Allan E. RettieDrug Metabolism and Disposition November 2015, 43 (11) 1661-1669; DOI: https://doi.org/10.1124/dmd.115.065623
McLachlan, Andrew J.
- You have accessIn Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine MetabolismPorntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew RowlandDrug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790
McLaughlin, Lesley A.
- You have accessDefining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse ModelNico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland WolfDrug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656
Meucci, Elisabetta
- You have accessInhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising DrugsAlvaro Mordente, Andrea Silvestrini, Giuseppe Ettore Martorana, Daniela Tavian and Elisabetta MeucciDrug Metabolism and Disposition November 2015, 43 (11) 1691-1701; DOI: https://doi.org/10.1124/dmd.115.065110
Miners, John O.
- You have accessIn Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine MetabolismPorntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew RowlandDrug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790
Mordente, Alvaro
- You have accessInhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising DrugsAlvaro Mordente, Andrea Silvestrini, Giuseppe Ettore Martorana, Daniela Tavian and Elisabetta MeucciDrug Metabolism and Disposition November 2015, 43 (11) 1691-1701; DOI: https://doi.org/10.1124/dmd.115.065110
Morse, Bridget L.
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
N
Neuvonen, Mikko
- You have accessClopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate SimvastatinMatti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. BackmanDrug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938
Neuvonen, Pertti J.
- You have accessClopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate SimvastatinMatti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. BackmanDrug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938
Niemi, Mikko
- You have accessClopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate SimvastatinMatti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. BackmanDrug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938
Nikolic, Dejan
- You have accessHigh-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical InteractionsGuannan Li, Ke Huang, Dejan Nikolic and Richard B. van BreemenDrug Metabolism and Disposition November 2015, 43 (11) 1670-1678; DOI: https://doi.org/10.1124/dmd.115.065987
Nozaki, Mayuka
- You have accessPrediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte AssayTakeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei ItoDrug Metabolism and Disposition November 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425
O
Oberlies, Nicholas H.
- You have accessChemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan GlucuronidesBrandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition November 2015, 43 (11) 1734-1743; DOI: https://doi.org/10.1124/dmd.115.066076
Ogilvie, Brian W.
- You have accessThe Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 ExperimentsLois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew ParkinsonDrug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
Ohtake, Hiroto
- You have accessNew Photosafety Assessment Strategy Based on the Photochemical and Pharmacokinetic Properties of Both Parent Chemicals and MetabolitesMasashi Kato, Gen Suzuki, Hiroto Ohtake, Yoshiki Seto and Satomi OnoueDrug Metabolism and Disposition November 2015, 43 (11) 1815-1822; DOI: https://doi.org/10.1124/dmd.115.065060
Onoue, Satomi
- You have accessNew Photosafety Assessment Strategy Based on the Photochemical and Pharmacokinetic Properties of Both Parent Chemicals and MetabolitesMasashi Kato, Gen Suzuki, Hiroto Ohtake, Yoshiki Seto and Satomi OnoueDrug Metabolism and Disposition November 2015, 43 (11) 1815-1822; DOI: https://doi.org/10.1124/dmd.115.065060
Oswald, Stefan
- You have accessDefining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse ModelNico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland WolfDrug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656
Ottaviani, Giorgio
- You have accessA New Rapid In Vitro Assay for Assessing Reactivity of Acyl GlucuronidesSheng Zhong, Russell Jones, Wenzhe Lu, Simone Schadt and Giorgio OttavianiDrug Metabolism and Disposition November 2015, 43 (11) 1711-1717; DOI: https://doi.org/10.1124/dmd.115.066159
P
Paguigan, Noemi D.
- You have accessChemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan GlucuronidesBrandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition November 2015, 43 (11) 1734-1743; DOI: https://doi.org/10.1124/dmd.115.066076
Paine, Mary F.
- You have accessChemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan GlucuronidesBrandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies and Mary F. PaineDrug Metabolism and Disposition November 2015, 43 (11) 1734-1743; DOI: https://doi.org/10.1124/dmd.115.066076
Pan, Yongmei
- You have accessPotent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease InhibitorsHaichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne WangDrug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824
Paris, Brandy
- You have accessThe Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 ExperimentsLois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew ParkinsonDrug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
Parkinson, Andrew
- You have accessThe Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 ExperimentsLois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew ParkinsonDrug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
Parkinson, Oliver
- You have accessThe Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 ExperimentsLois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew ParkinsonDrug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
Petzuch, Barbara
- You have accessApplication of HC-AFW1 Hepatocarcinoma Cells for Mechanistic Studies: Regulation of Cytochrome P450 2B6 Expression by Dimethyl Sulfoxide and Early Growth Response 1Barbara Petzuch, Nicola Groll, Michael Schwarz and Albert BraeuningDrug Metabolism and Disposition November 2015, 43 (11) 1727-1733; DOI: https://doi.org/10.1124/dmd.115.064659
- You have accessComparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor AgonistsAlbert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael SchwarzDrug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Polasek, Thomas M.
- You have accessIn Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine MetabolismPorntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew RowlandDrug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790
R
Ragueneau-Majlessi, Isabelle
- You have accessPhysiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model VerificationJennifer E. Sager, Jingjing Yu, Isabelle Ragueneau-Majlessi and Nina IsoherranenDrug Metabolism and Disposition November 2015, 43 (11) 1823-1837; DOI: https://doi.org/10.1124/dmd.115.065920
Rettie, Allan E.
- You have accessP450-Based Drug-Drug Interactions of Amiodarone and its Metabolites: Diversity of Inhibitory MechanismsMatthew G. McDonald, Nicholas T. Au and Allan E. RettieDrug Metabolism and Disposition November 2015, 43 (11) 1661-1669; DOI: https://doi.org/10.1124/dmd.115.065623
Rode, Anja
- You have accessDefining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse ModelNico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland WolfDrug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656
Rowland, Andrew
- You have accessIn Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine MetabolismPorntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew RowlandDrug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790
S
Sager, Jennifer E.
- You have accessPhysiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model VerificationJennifer E. Sager, Jingjing Yu, Isabelle Ragueneau-Majlessi and Nina IsoherranenDrug Metabolism and Disposition November 2015, 43 (11) 1823-1837; DOI: https://doi.org/10.1124/dmd.115.065920
Schadt, Simone
- You have accessA New Rapid In Vitro Assay for Assessing Reactivity of Acyl GlucuronidesSheng Zhong, Russell Jones, Wenzhe Lu, Simone Schadt and Giorgio OttavianiDrug Metabolism and Disposition November 2015, 43 (11) 1711-1717; DOI: https://doi.org/10.1124/dmd.115.066159
Scheer, Nico
- You have accessDefining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse ModelNico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland WolfDrug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656
Scheib, Rachel
- You have accessIn Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter MiceKazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. SchuetzDrug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078
Schroth, Werner
- You have accessComparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor AgonistsAlbert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael SchwarzDrug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Schuetz, Erin G.
- You have accessIn Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter MiceKazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. SchuetzDrug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078
Schwarz, Michael
- You have accessApplication of HC-AFW1 Hepatocarcinoma Cells for Mechanistic Studies: Regulation of Cytochrome P450 2B6 Expression by Dimethyl Sulfoxide and Early Growth Response 1Barbara Petzuch, Nicola Groll, Michael Schwarz and Albert BraeuningDrug Metabolism and Disposition November 2015, 43 (11) 1727-1733; DOI: https://doi.org/10.1124/dmd.115.064659
- You have accessComparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor AgonistsAlbert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael SchwarzDrug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Sekine, Shuichi
- You have accessPrediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte AssayTakeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei ItoDrug Metabolism and Disposition November 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425
Seto, Yoshiki
- You have accessNew Photosafety Assessment Strategy Based on the Photochemical and Pharmacokinetic Properties of Both Parent Chemicals and MetabolitesMasashi Kato, Gen Suzuki, Hiroto Ohtake, Yoshiki Seto and Satomi OnoueDrug Metabolism and Disposition November 2015, 43 (11) 1815-1822; DOI: https://doi.org/10.1124/dmd.115.065060
Shen, Hong
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Shu, Yue-Zhong
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Silvestrini, Andrea
- You have accessInhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising DrugsAlvaro Mordente, Andrea Silvestrini, Giuseppe Ettore Martorana, Daniela Tavian and Elisabetta MeucciDrug Metabolism and Disposition November 2015, 43 (11) 1691-1701; DOI: https://doi.org/10.1124/dmd.115.065110
Smith, Brian D.
- You have accessThe Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 ExperimentsLois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew ParkinsonDrug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597
Sorich, Michael J.
- You have accessIn Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine MetabolismPorntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew RowlandDrug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790
Spiekerman, Charles F.
- You have accessModulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging StudyLi Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. UnadkatDrug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
Su, Hong
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Susukida, Takeshi
- You have accessPrediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte AssayTakeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei ItoDrug Metabolism and Disposition November 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425
Suzuki, Gen
- You have accessNew Photosafety Assessment Strategy Based on the Photochemical and Pharmacokinetic Properties of Both Parent Chemicals and MetabolitesMasashi Kato, Gen Suzuki, Hiroto Ohtake, Yoshiki Seto and Satomi OnoueDrug Metabolism and Disposition November 2015, 43 (11) 1815-1822; DOI: https://doi.org/10.1124/dmd.115.065060
Swaan, Peter W.
- You have accessPotent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease InhibitorsHaichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne WangDrug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824
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Tavian, Daniela
- You have accessInhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising DrugsAlvaro Mordente, Andrea Silvestrini, Giuseppe Ettore Martorana, Daniela Tavian and Elisabetta MeucciDrug Metabolism and Disposition November 2015, 43 (11) 1691-1701; DOI: https://doi.org/10.1124/dmd.115.065110
Thirumaran, Ranjit K.
- You have accessIn Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter MiceKazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. SchuetzDrug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078
Thomas, Maria
- You have accessComparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor AgonistsAlbert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael SchwarzDrug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Tokizono, Mayuko
- You have accessPrediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte AssayTakeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei ItoDrug Metabolism and Disposition November 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425
Tornio, Aleksi
- You have accessClopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate SimvastatinMatti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. BackmanDrug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938
Troberg, Johanna
- You have accessThe Polymorphic Variant P24T of UDP-Glucuronosyltransferase 1A4 and Its Unusual ConsequencesJohanna Troberg and Moshe FinelDrug Metabolism and Disposition November 2015, 43 (11) 1769-1772; DOI: https://doi.org/10.1124/dmd.115.065680
Tucker, Geoffrey T.
- You have accessIn Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine MetabolismPorntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew RowlandDrug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790
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Unadkat, Jashvant D.
- You have accessModulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging StudyLi Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. UnadkatDrug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
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van Breemen, Richard B.
- You have accessHigh-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical InteractionsGuannan Li, Ke Huang, Dejan Nikolic and Richard B. van BreemenDrug Metabolism and Disposition November 2015, 43 (11) 1670-1678; DOI: https://doi.org/10.1124/dmd.115.065987
Vetter, Silvia
- You have accessComparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor AgonistsAlbert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael SchwarzDrug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
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Wang, Joanne
- You have accessPotent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease InhibitorsHaichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne WangDrug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824
Weiss, Thomas S.
- You have accessComparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor AgonistsAlbert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael SchwarzDrug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Wolf, C. Roland
- You have accessDefining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse ModelNico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland WolfDrug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656
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Xu, Ping
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
Y
Yasuda, Kazuto
- You have accessIn Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter MiceKazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. SchuetzDrug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078
Yu, Jingjing
- You have accessPhysiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model VerificationJennifer E. Sager, Jingjing Yu, Isabelle Ragueneau-Majlessi and Nina IsoherranenDrug Metabolism and Disposition November 2015, 43 (11) 1823-1837; DOI: https://doi.org/10.1124/dmd.115.065920
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Zanger, Ulrich M.
- You have accessComparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor AgonistsAlbert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael SchwarzDrug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Zeller, Eva
- You have accessComparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor AgonistsAlbert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael SchwarzDrug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Zhang, Ji
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
Zhang, Lisa
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Zhang, Mian
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
Zhang, Yueping
- You have accessRosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte UptakeBridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong LaiDrug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Zhong, Dafang
- You have accessFasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver InjuryXiuli Li, Kan Zhong, Zitao Guo, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition November 2015, 43 (11) 1751-1759; DOI: https://doi.org/10.1124/dmd.115.064121
Zhong, Kan
- You have accessFasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver InjuryXiuli Li, Kan Zhong, Zitao Guo, Dafang Zhong and Xiaoyan ChenDrug Metabolism and Disposition November 2015, 43 (11) 1751-1759; DOI: https://doi.org/10.1124/dmd.115.064121
Zhong, Sheng
- You have accessA New Rapid In Vitro Assay for Assessing Reactivity of Acyl GlucuronidesSheng Zhong, Russell Jones, Wenzhe Lu, Simone Schadt and Giorgio OttavianiDrug Metabolism and Disposition November 2015, 43 (11) 1711-1717; DOI: https://doi.org/10.1124/dmd.115.066159
Zhong, Zeyu
- You have accessCombined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral AdministrationCan Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong LiuDrug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
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