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Index by author

November 01, 2015; Volume 43,Issue 11

A

  1. Au, Nicholas T.

    1. P450-Based Drug-Drug Interactions of Amiodarone and its Metabolites: Diversity of Inhibitory Mechanisms
      Matthew G. McDonald, Nicholas T. Au and Allan E. Rettie
      Drug Metabolism and Disposition November 2015, 43 (11) 1661-1669; DOI: https://doi.org/10.1124/dmd.115.065623

B

  1. Backman, Janne T.

    1. Clopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate Simvastatin
      Matti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938

  2. Blobaum, Anna L.

    1. A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo
      Anna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott Daniels
      Drug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006

  3. Braeuning, Albert

    1. Application of HC-AFW1 Hepatocarcinoma Cells for Mechanistic Studies: Regulation of Cytochrome P450 2B6 Expression by Dimethyl Sulfoxide and Early Growth Response 1
      Barbara Petzuch, Nicola Groll, Michael Schwarz and Albert Braeuning
      Drug Metabolism and Disposition November 2015, 43 (11) 1727-1733; DOI: https://doi.org/10.1124/dmd.115.064659
    2. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
      Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
      Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

  4. Bridges, Thomas M.

    1. A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo
      Anna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott Daniels
      Drug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006

  5. Buckley, David B.

    1. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments
      Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson
      Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597

  6. Busch, Diana

    1. Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model
      Nico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656

  7. Byers, Frank W.

    1. A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo
      Anna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott Daniels
      Drug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006

C

  1. Cai, Hong

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

  2. Chaudhry, Amarjit

    1. In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
      Kazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. Schuetz
      Drug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078

  3. Chen, Xiaoyan

    1. Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury
      Xiuli Li, Kan Zhong, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition November 2015, 43 (11) 1751-1759; DOI: https://doi.org/10.1124/dmd.115.064121

  4. Chen, Yang

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881

  5. Cline, Cynthia

    1. In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
      Kazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. Schuetz
      Drug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078

  6. Collier, Ann C.

    1. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study
      Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

  7. Conn, P. Jeffrey

    1. A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo
      Anna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott Daniels
      Drug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006

D

  1. Daniels, J. Scott

    1. A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo
      Anna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott Daniels
      Drug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006

  2. Deo, Anand K.

    1. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study
      Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

  3. Dierks, Elizabeth A.

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

  4. Domino, Karen B.

    1. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study
      Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

  5. Duan, Haichuan

    1. Potent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease Inhibitors
      Haichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne Wang
      Drug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824

E

  1. Eary, Janet F.

    1. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study
      Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

F

  1. Finel, Moshe

    1. The Polymorphic Variant P24T of UDP-Glucuronosyltransferase 1A4 and Its Unusual Consequences
      Johanna Troberg and Moshe Finel
      Drug Metabolism and Disposition November 2015, 43 (11) 1769-1772; DOI: https://doi.org/10.1124/dmd.115.065680

  2. Foti, Robert S.

    1. Potent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease Inhibitors
      Haichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne Wang
      Drug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824

  3. Fox, Maxine

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

G

  1. Ganguly, Samit

    1. In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
      Kazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. Schuetz
      Drug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078

  2. Graf, Tyler N.

    1. Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides
      Brandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition November 2015, 43 (11) 1734-1743; DOI: https://doi.org/10.1124/dmd.115.066076

  3. Groll, Nicola

    1. Application of HC-AFW1 Hepatocarcinoma Cells for Mechanistic Studies: Regulation of Cytochrome P450 2B6 Expression by Dimethyl Sulfoxide and Early Growth Response 1
      Barbara Petzuch, Nicola Groll, Michael Schwarz and Albert Braeuning
      Drug Metabolism and Disposition November 2015, 43 (11) 1727-1733; DOI: https://doi.org/10.1124/dmd.115.064659

  4. Gu, Xiaomei

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

  5. Gufford, Brandon T.

    1. Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides
      Brandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition November 2015, 43 (11) 1734-1743; DOI: https://doi.org/10.1124/dmd.115.066076

  6. Guo, Haifang

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881

  7. Guo, Zitao

    1. Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury
      Xiuli Li, Kan Zhong, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition November 2015, 43 (11) 1751-1759; DOI: https://doi.org/10.1124/dmd.115.064121

H

  1. Haupt, Lois J.

    1. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments
      Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson
      Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597

  2. Henderson, Colin. J.

    1. Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model
      Nico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656

  3. Hofmann, Ute

    1. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
      Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
      Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

  4. Hsiao, Peng

    1. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study
      Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

  5. Hu, Mengyue

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881

  6. Hu, Tao

    1. Potent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease Inhibitors
      Haichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne Wang
      Drug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824

  7. Huang, Ke

    1. High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions
      Guannan Li, Ke Huang, Dejan Nikolic and Richard B. van Breemen
      Drug Metabolism and Disposition November 2015, 43 (11) 1670-1678; DOI: https://doi.org/10.1124/dmd.115.065987

  8. Humphreys, W. Griffith

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

I

  1. Isoherranen, Nina

    1. Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification
      Jennifer E. Sager, Jingjing Yu, Isabelle Ragueneau-Majlessi and Nina Isoherranen
      Drug Metabolism and Disposition November 2015, 43 (11) 1823-1837; DOI: https://doi.org/10.1124/dmd.115.065920

  2. Itkonen, Matti K.

    1. Clopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate Simvastatin
      Matti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938

  3. Ito, Kousei

    1. Prediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte Assay
      Takeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei Ito
      Drug Metabolism and Disposition November 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425

J

  1. Johänning, Janina

    1. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
      Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
      Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

  2. Jones, Russell

    1. A New Rapid In Vitro Assay for Assessing Reactivity of Acyl Glucuronides
      Sheng Zhong, Russell Jones, Wenzhe Lu, Simone Schadt and Giorgio Ottaviani
      Drug Metabolism and Disposition November 2015, 43 (11) 1711-1717; DOI: https://doi.org/10.1124/dmd.115.066159

K

  1. Kapelyukh, Yury

    1. Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model
      Nico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656

  2. Kato, Masashi

    1. New Photosafety Assessment Strategy Based on the Photochemical and Pharmacokinetic Properties of Both Parent Chemicals and Metabolites
      Masashi Kato, Gen Suzuki, Hiroto Ohtake, Yoshiki Seto and Satomi Onoue
      Drug Metabolism and Disposition November 2015, 43 (11) 1815-1822; DOI: https://doi.org/10.1124/dmd.115.065060

  3. Kazmi, Faraz

    1. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments
      Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson
      Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597

  4. Kim, Richard B.

    1. In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
      Kazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. Schuetz
      Drug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078

  5. Korprasertthaworn, Porntipa

    1. In Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine Metabolism
      Porntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew Rowland
      Drug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790

L

  1. Lai, Yurong

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

  2. Leatherman, Sarah

    1. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments
      Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson
      Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597

  3. Li, Feng

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881

  4. Li, Guannan

    1. High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions
      Guannan Li, Ke Huang, Dejan Nikolic and Richard B. van Breemen
      Drug Metabolism and Disposition November 2015, 43 (11) 1670-1678; DOI: https://doi.org/10.1124/dmd.115.065987

  5. Li, Jia

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881

  6. Li, Xiuli

    1. Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury
      Xiuli Li, Kan Zhong, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition November 2015, 43 (11) 1751-1759; DOI: https://doi.org/10.1124/dmd.115.064121

  7. Li, Ying

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881

  8. Lin, De

    1. Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model
      Nico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656

  9. Lin, Yvonne S.

    1. In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
      Kazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. Schuetz
      Drug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078

  10. Lindsley, Craig W.

    1. A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo
      Anna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott Daniels
      Drug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006

  11. Link, Jeanne M.

    1. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study
      Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

  12. Liu, Can

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881

  13. Liu, Li

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
    2. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study
      Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

  14. Liu, Xiaodong

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881

  15. Locuson, Charles W.

    1. A Screen of Approved Drugs Identifies the Androgen Receptor Antagonist Flutamide and Its Pharmacologically Active Metabolite 2-Hydroxy-Flutamide as Heterotropic Activators of Cytochrome P450 3A In Vitro and In Vivo
      Anna L. Blobaum, Frank W. Byers, Thomas M. Bridges, Charles W. Locuson, P. Jeffrey Conn, Craig W. Lindsley and J. Scott Daniels
      Drug Metabolism and Disposition November 2015, 43 (11) 1718-1726; DOI: https://doi.org/10.1124/dmd.115.064006

  16. Lu, Wenzhe

    1. A New Rapid In Vitro Assay for Assessing Reactivity of Acyl Glucuronides
      Sheng Zhong, Russell Jones, Wenzhe Lu, Simone Schadt and Giorgio Ottaviani
      Drug Metabolism and Disposition November 2015, 43 (11) 1711-1717; DOI: https://doi.org/10.1124/dmd.115.066159

  17. Luk, Chiuwa E.

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

M

  1. MacGuire, Jamus G.

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

  2. Mankoff, David A.

    1. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study
      Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

  3. Marathe, Punit

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

  4. Martorana, Giuseppe Ettore

    1. Inhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising Drugs
      Alvaro Mordente, Andrea Silvestrini, Giuseppe Ettore Martorana, Daniela Tavian and Elisabetta Meucci
      Drug Metabolism and Disposition November 2015, 43 (11) 1691-1701; DOI: https://doi.org/10.1124/dmd.115.065110

  5. McDonald, Matthew G.

    1. P450-Based Drug-Drug Interactions of Amiodarone and its Metabolites: Diversity of Inhibitory Mechanisms
      Matthew G. McDonald, Nicholas T. Au and Allan E. Rettie
      Drug Metabolism and Disposition November 2015, 43 (11) 1661-1669; DOI: https://doi.org/10.1124/dmd.115.065623

  6. McLachlan, Andrew J.

    1. In Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine Metabolism
      Porntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew Rowland
      Drug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790

  7. McLaughlin, Lesley A.

    1. Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model
      Nico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656

  8. Meucci, Elisabetta

    1. Inhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising Drugs
      Alvaro Mordente, Andrea Silvestrini, Giuseppe Ettore Martorana, Daniela Tavian and Elisabetta Meucci
      Drug Metabolism and Disposition November 2015, 43 (11) 1691-1701; DOI: https://doi.org/10.1124/dmd.115.065110

  9. Miners, John O.

    1. In Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine Metabolism
      Porntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew Rowland
      Drug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790

  10. Mordente, Alvaro

    1. Inhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising Drugs
      Alvaro Mordente, Andrea Silvestrini, Giuseppe Ettore Martorana, Daniela Tavian and Elisabetta Meucci
      Drug Metabolism and Disposition November 2015, 43 (11) 1691-1701; DOI: https://doi.org/10.1124/dmd.115.065110

  11. Morse, Bridget L.

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

N

  1. Neuvonen, Mikko

    1. Clopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate Simvastatin
      Matti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938

  2. Neuvonen, Pertti J.

    1. Clopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate Simvastatin
      Matti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938

  3. Niemi, Mikko

    1. Clopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate Simvastatin
      Matti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938

  4. Nikolic, Dejan

    1. High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions
      Guannan Li, Ke Huang, Dejan Nikolic and Richard B. van Breemen
      Drug Metabolism and Disposition November 2015, 43 (11) 1670-1678; DOI: https://doi.org/10.1124/dmd.115.065987

  5. Nozaki, Mayuka

    1. Prediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte Assay
      Takeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei Ito
      Drug Metabolism and Disposition November 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425

O

  1. Oberlies, Nicholas H.

    1. Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides
      Brandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition November 2015, 43 (11) 1734-1743; DOI: https://doi.org/10.1124/dmd.115.066076

  2. Ogilvie, Brian W.

    1. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments
      Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson
      Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597

  3. Ohtake, Hiroto

    1. New Photosafety Assessment Strategy Based on the Photochemical and Pharmacokinetic Properties of Both Parent Chemicals and Metabolites
      Masashi Kato, Gen Suzuki, Hiroto Ohtake, Yoshiki Seto and Satomi Onoue
      Drug Metabolism and Disposition November 2015, 43 (11) 1815-1822; DOI: https://doi.org/10.1124/dmd.115.065060

  4. Onoue, Satomi

    1. New Photosafety Assessment Strategy Based on the Photochemical and Pharmacokinetic Properties of Both Parent Chemicals and Metabolites
      Masashi Kato, Gen Suzuki, Hiroto Ohtake, Yoshiki Seto and Satomi Onoue
      Drug Metabolism and Disposition November 2015, 43 (11) 1815-1822; DOI: https://doi.org/10.1124/dmd.115.065060

  5. Oswald, Stefan

    1. Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model
      Nico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656

  6. Ottaviani, Giorgio

    1. A New Rapid In Vitro Assay for Assessing Reactivity of Acyl Glucuronides
      Sheng Zhong, Russell Jones, Wenzhe Lu, Simone Schadt and Giorgio Ottaviani
      Drug Metabolism and Disposition November 2015, 43 (11) 1711-1717; DOI: https://doi.org/10.1124/dmd.115.066159

P

  1. Paguigan, Noemi D.

    1. Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides
      Brandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition November 2015, 43 (11) 1734-1743; DOI: https://doi.org/10.1124/dmd.115.066076

  2. Paine, Mary F.

    1. Chemoenzymatic Synthesis, Characterization, and Scale-Up of Milk Thistle Flavonolignan Glucuronides
      Brandon T. Gufford, Tyler N. Graf, Noemi D. Paguigan, Nicholas H. Oberlies and Mary F. Paine
      Drug Metabolism and Disposition November 2015, 43 (11) 1734-1743; DOI: https://doi.org/10.1124/dmd.115.066076

  3. Pan, Yongmei

    1. Potent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease Inhibitors
      Haichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne Wang
      Drug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824

  4. Paris, Brandy

    1. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments
      Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson
      Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597

  5. Parkinson, Andrew

    1. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments
      Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson
      Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597

  6. Parkinson, Oliver

    1. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments
      Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson
      Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597

  7. Petzuch, Barbara

    1. Application of HC-AFW1 Hepatocarcinoma Cells for Mechanistic Studies: Regulation of Cytochrome P450 2B6 Expression by Dimethyl Sulfoxide and Early Growth Response 1
      Barbara Petzuch, Nicola Groll, Michael Schwarz and Albert Braeuning
      Drug Metabolism and Disposition November 2015, 43 (11) 1727-1733; DOI: https://doi.org/10.1124/dmd.115.064659
    2. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
      Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
      Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

  8. Polasek, Thomas M.

    1. In Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine Metabolism
      Porntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew Rowland
      Drug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790

R

  1. Ragueneau-Majlessi, Isabelle

    1. Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification
      Jennifer E. Sager, Jingjing Yu, Isabelle Ragueneau-Majlessi and Nina Isoherranen
      Drug Metabolism and Disposition November 2015, 43 (11) 1823-1837; DOI: https://doi.org/10.1124/dmd.115.065920

  2. Rettie, Allan E.

    1. P450-Based Drug-Drug Interactions of Amiodarone and its Metabolites: Diversity of Inhibitory Mechanisms
      Matthew G. McDonald, Nicholas T. Au and Allan E. Rettie
      Drug Metabolism and Disposition November 2015, 43 (11) 1661-1669; DOI: https://doi.org/10.1124/dmd.115.065623

  3. Rode, Anja

    1. Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model
      Nico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656

  4. Rowland, Andrew

    1. In Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine Metabolism
      Porntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew Rowland
      Drug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790

S

  1. Sager, Jennifer E.

    1. Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification
      Jennifer E. Sager, Jingjing Yu, Isabelle Ragueneau-Majlessi and Nina Isoherranen
      Drug Metabolism and Disposition November 2015, 43 (11) 1823-1837; DOI: https://doi.org/10.1124/dmd.115.065920

  2. Schadt, Simone

    1. A New Rapid In Vitro Assay for Assessing Reactivity of Acyl Glucuronides
      Sheng Zhong, Russell Jones, Wenzhe Lu, Simone Schadt and Giorgio Ottaviani
      Drug Metabolism and Disposition November 2015, 43 (11) 1711-1717; DOI: https://doi.org/10.1124/dmd.115.066159

  3. Scheer, Nico

    1. Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model
      Nico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656

  4. Scheib, Rachel

    1. In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
      Kazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. Schuetz
      Drug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078

  5. Schroth, Werner

    1. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
      Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
      Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

  6. Schuetz, Erin G.

    1. In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
      Kazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. Schuetz
      Drug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078

  7. Schwarz, Michael

    1. Application of HC-AFW1 Hepatocarcinoma Cells for Mechanistic Studies: Regulation of Cytochrome P450 2B6 Expression by Dimethyl Sulfoxide and Early Growth Response 1
      Barbara Petzuch, Nicola Groll, Michael Schwarz and Albert Braeuning
      Drug Metabolism and Disposition November 2015, 43 (11) 1727-1733; DOI: https://doi.org/10.1124/dmd.115.064659
    2. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
      Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
      Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

  8. Sekine, Shuichi

    1. Prediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte Assay
      Takeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei Ito
      Drug Metabolism and Disposition November 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425

  9. Seto, Yoshiki

    1. New Photosafety Assessment Strategy Based on the Photochemical and Pharmacokinetic Properties of Both Parent Chemicals and Metabolites
      Masashi Kato, Gen Suzuki, Hiroto Ohtake, Yoshiki Seto and Satomi Onoue
      Drug Metabolism and Disposition November 2015, 43 (11) 1815-1822; DOI: https://doi.org/10.1124/dmd.115.065060

  10. Shen, Hong

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

  11. Shu, Yue-Zhong

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

  12. Silvestrini, Andrea

    1. Inhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising Drugs
      Alvaro Mordente, Andrea Silvestrini, Giuseppe Ettore Martorana, Daniela Tavian and Elisabetta Meucci
      Drug Metabolism and Disposition November 2015, 43 (11) 1691-1701; DOI: https://doi.org/10.1124/dmd.115.065110

  13. Smith, Brian D.

    1. The Reliability of Estimating Ki Values for Direct, Reversible Inhibition of Cytochrome P450 Enzymes from Corresponding IC50 Values: A Retrospective Analysis of 343 Experiments
      Lois J. Haupt, Faraz Kazmi, Brian W. Ogilvie, David B. Buckley, Brian D. Smith, Sarah Leatherman, Brandy Paris, Oliver Parkinson and Andrew Parkinson
      Drug Metabolism and Disposition November 2015, 43 (11) 1744-1750; DOI: https://doi.org/10.1124/dmd.115.066597

  14. Sorich, Michael J.

    1. In Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine Metabolism
      Porntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew Rowland
      Drug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790

  15. Spiekerman, Charles F.

    1. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study
      Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

  16. Su, Hong

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

  17. Susukida, Takeshi

    1. Prediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte Assay
      Takeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei Ito
      Drug Metabolism and Disposition November 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425

  18. Suzuki, Gen

    1. New Photosafety Assessment Strategy Based on the Photochemical and Pharmacokinetic Properties of Both Parent Chemicals and Metabolites
      Masashi Kato, Gen Suzuki, Hiroto Ohtake, Yoshiki Seto and Satomi Onoue
      Drug Metabolism and Disposition November 2015, 43 (11) 1815-1822; DOI: https://doi.org/10.1124/dmd.115.065060

  19. Swaan, Peter W.

    1. Potent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease Inhibitors
      Haichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne Wang
      Drug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824

T

  1. Tavian, Daniela

    1. Inhibition of Anthracycline Alcohol Metabolite Formation in Human Heart Cytosol: A Potential Role for Several Promising Drugs
      Alvaro Mordente, Andrea Silvestrini, Giuseppe Ettore Martorana, Daniela Tavian and Elisabetta Meucci
      Drug Metabolism and Disposition November 2015, 43 (11) 1691-1701; DOI: https://doi.org/10.1124/dmd.115.065110

  2. Thirumaran, Ranjit K.

    1. In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
      Kazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. Schuetz
      Drug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078

  3. Thomas, Maria

    1. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
      Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
      Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

  4. Tokizono, Mayuko

    1. Prediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte Assay
      Takeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei Ito
      Drug Metabolism and Disposition November 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425

  5. Tornio, Aleksi

    1. Clopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate Simvastatin
      Matti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
      Drug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938

  6. Troberg, Johanna

    1. The Polymorphic Variant P24T of UDP-Glucuronosyltransferase 1A4 and Its Unusual Consequences
      Johanna Troberg and Moshe Finel
      Drug Metabolism and Disposition November 2015, 43 (11) 1769-1772; DOI: https://doi.org/10.1124/dmd.115.065680

  7. Tucker, Geoffrey T.

    1. In Vitro Characterization of the Human Liver Microsomal Kinetics and Reaction Phenotyping of Olanzapine Metabolism
      Porntipa Korprasertthaworn, Thomas M. Polasek, Michael J. Sorich, Andrew J. McLachlan, John O. Miners, Geoffrey T. Tucker and Andrew Rowland
      Drug Metabolism and Disposition November 2015, 43 (11) 1806-1814; DOI: https://doi.org/10.1124/dmd.115.064790

U

  1. Unadkat, Jashvant D.

    1. Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study
      Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
      Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

V

  1. van Breemen, Richard B.

    1. High-Throughput Cytochrome P450 Cocktail Inhibition Assay for Assessing Drug-Drug and Drug-Botanical Interactions
      Guannan Li, Ke Huang, Dejan Nikolic and Richard B. van Breemen
      Drug Metabolism and Disposition November 2015, 43 (11) 1670-1678; DOI: https://doi.org/10.1124/dmd.115.065987

  2. Vetter, Silvia

    1. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
      Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
      Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

W

  1. Wang, Joanne

    1. Potent and Selective Inhibition of Plasma Membrane Monoamine Transporter by HIV Protease Inhibitors
      Haichuan Duan, Tao Hu, Robert S. Foti, Yongmei Pan, Peter W. Swaan and Joanne Wang
      Drug Metabolism and Disposition November 2015, 43 (11) 1773-1780; DOI: https://doi.org/10.1124/dmd.115.064824

  2. Weiss, Thomas S.

    1. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
      Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
      Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

  3. Wolf, C. Roland

    1. Defining Human Pathways of Drug Metabolism In Vivo through the Development of a Multiple Humanized Mouse Model
      Nico Scheer, Yury Kapelyukh, Anja Rode, Stefan Oswald, Diana Busch, Lesley A. McLaughlin, De Lin, Colin. J. Henderson and C. Roland Wolf
      Drug Metabolism and Disposition November 2015, 43 (11) 1679-1690; DOI: https://doi.org/10.1124/dmd.115.065656

X

  1. Xu, Ping

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881

Y

  1. Yasuda, Kazuto

    1. In Vivo Imaging of Human MDR1 Transcription in the Brain and Spine of MDR1-Luciferase Reporter Mice
      Kazuto Yasuda, Cynthia Cline, Yvonne S. Lin, Rachel Scheib, Samit Ganguly, Ranjit K. Thirumaran, Amarjit Chaudhry, Richard B. Kim and Erin G. Schuetz
      Drug Metabolism and Disposition November 2015, 43 (11) 1646-1654; DOI: https://doi.org/10.1124/dmd.115.065078

  2. Yu, Jingjing

    1. Physiologically Based Pharmacokinetic (PBPK) Modeling and Simulation Approaches: A Systematic Review of Published Models, Applications, and Model Verification
      Jennifer E. Sager, Jingjing Yu, Isabelle Ragueneau-Majlessi and Nina Isoherranen
      Drug Metabolism and Disposition November 2015, 43 (11) 1823-1837; DOI: https://doi.org/10.1124/dmd.115.065920

Z

  1. Zanger, Ulrich M.

    1. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
      Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
      Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

  2. Zeller, Eva

    1. Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
      Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
      Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

  3. Zhang, Ji

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881

  4. Zhang, Lisa

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

  5. Zhang, Mian

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881

  6. Zhang, Yueping

    1. Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
      Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
      Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946

  7. Zhong, Dafang

    1. Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury
      Xiuli Li, Kan Zhong, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition November 2015, 43 (11) 1751-1759; DOI: https://doi.org/10.1124/dmd.115.064121

  8. Zhong, Kan

    1. Fasiglifam (TAK-875) Inhibits Hepatobiliary Transporters: A Possible Factor Contributing to Fasiglifam-Induced Liver Injury
      Xiuli Li, Kan Zhong, Zitao Guo, Dafang Zhong and Xiaoyan Chen
      Drug Metabolism and Disposition November 2015, 43 (11) 1751-1759; DOI: https://doi.org/10.1124/dmd.115.064121

  9. Zhong, Sheng

    1. A New Rapid In Vitro Assay for Assessing Reactivity of Acyl Glucuronides
      Sheng Zhong, Russell Jones, Wenzhe Lu, Simone Schadt and Giorgio Ottaviani
      Drug Metabolism and Disposition November 2015, 43 (11) 1711-1717; DOI: https://doi.org/10.1124/dmd.115.066159

  10. Zhong, Zeyu

    1. Combined Contribution of Increased Intestinal Permeability and Inhibited Deglycosylation of Ginsenoside Rb1 in the Intestinal Tract to the Enhancement of Ginsenoside Rb1 Exposure in Diabetic Rats after Oral Administration
      Can Liu, Mengyue Hu, Haifang Guo, Mian Zhang, Ji Zhang, Feng Li, Zeyu Zhong, Yang Chen, Ying Li, Ping Xu, Jia Li, Li Liu and Xiaodong Liu
      Drug Metabolism and Disposition November 2015, 43 (11) 1702-1710; DOI: https://doi.org/10.1124/dmd.115.064881
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