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Research ArticleArticle

Clopidogrel Has No Clinically Meaningful Effect on the Pharmacokinetics of the Organic Anion Transporting Polypeptide 1B1 and Cytochrome P450 3A4 Substrate Simvastatin

Matti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
Drug Metabolism and Disposition November 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938
Matti K. Itkonen
Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Aleksi Tornio
Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Mikko Neuvonen
Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Pertti J. Neuvonen
Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Mikko Niemi
Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Janne T. Backman
Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
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Article Information

vol. 43 no. 11 1655-1660
DOI 
https://doi.org/10.1124/dmd.115.065938
PubMed 
26329790

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received June 13, 2015
  • Accepted August 31, 2015
  • Published online September 29, 2015.

Article Versions

  • Earlier version (September 1, 2015 - 07:19).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Matti K. Itkonen,
  2. Aleksi Tornio,
  3. Mikko Neuvonen,
  4. Pertti J. Neuvonen,
  5. Mikko Niemi, and
  6. Janne T. Backman
  1. Department of Clinical Pharmacology, University of Helsinki and Helsinki University Hospital, Helsinki, Finland
  1. Address correspondence to:
    Dr. Janne T. Backman, Department of Clinical Pharmacology, University of Helsinki, Tukholmankatu 8, Biomedicum 2 C, 00014 University of Helsinki, Finland. E-mail: janne.backman{at}helsinki.fi
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Drug Metabolism and Disposition: 43 (11)
Drug Metabolism and Disposition
Vol. 43, Issue 11
1 Nov 2015
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Research ArticleArticle

Effect of Clopidogrel on the Pharmacokinetics of Simvastatin

Matti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
Drug Metabolism and Disposition November 1, 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938

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Research ArticleArticle

Effect of Clopidogrel on the Pharmacokinetics of Simvastatin

Matti K. Itkonen, Aleksi Tornio, Mikko Neuvonen, Pertti J. Neuvonen, Mikko Niemi and Janne T. Backman
Drug Metabolism and Disposition November 1, 2015, 43 (11) 1655-1660; DOI: https://doi.org/10.1124/dmd.115.065938
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