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Research ArticleArticle

P450-Based Drug-Drug Interactions of Amiodarone and its Metabolites: Diversity of Inhibitory Mechanisms

Matthew G. McDonald, Nicholas T. Au and Allan E. Rettie
Drug Metabolism and Disposition November 2015, 43 (11) 1661-1669; DOI: https://doi.org/10.1124/dmd.115.065623

Article Information

vol. 43 no. 11 1661-1669
DOI 
https://doi.org/10.1124/dmd.115.065623
PubMed 
26296708
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 21, 2015
  • Accepted August 20, 2015
  • Published online September 29, 2015.

Article Versions

Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Matthew G. McDonald,
  2. Nicholas T. Au, and
  3. Allan E. Rettie
  1. Department of Medicinal Chemistry, University of Washington, Seattle, Washington (M.G.M., N.T.A., A.E.R.)
  1. Address correspondence to:
    Allan E. Rettie, Department of Medicinal Chemistry, University of Washington, Box 357610, Seattle, WA, 98195. E-mail: rettie{at}u.washington.edu
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Research ArticleArticle

Inhibitory Metabolites in Amiodarone Drug-Drug Interactions

Matthew G. McDonald, Nicholas T. Au and Allan E. Rettie
Drug Metabolism and Disposition November 1, 2015, 43 (11) 1661-1669; DOI: https://doi.org/10.1124/dmd.115.065623
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