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Research ArticleArticle

Prediction of the Clinical Risk of Drug-Induced Cholestatic Liver Injury Using an In Vitro Sandwich Cultured Hepatocyte Assay

Takeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei Ito
Drug Metabolism and Disposition November 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425

Article Information

vol. 43 no. 11 1760-1768
DOI 
https://doi.org/10.1124/dmd.115.065425
PubMed 
26329788
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 13, 2015
  • Accepted August 31, 2015
  • Published online October 12, 2015.

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Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Takeshi Susukida,
  2. Shuichi Sekine,
  3. Mayuka Nozaki,
  4. Mayuko Tokizono, and
  5. Kousei Ito
  1. Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Chuo-ku, Chiba, Japan
  1. Address correspondence to:
    Dr. Kousei Ito, Laboratory of Biopharmaceutics, Graduate School of Pharmaceutical Sciences, Chiba University, Inohana 1-8-1, Chuo-ku, Chiba 260-8675, Japan. E-mail: itokousei{at}chiba-u.jp
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Prediction of Cholestatic DILI Risk

Takeshi Susukida, Shuichi Sekine, Mayuka Nozaki, Mayuko Tokizono and Kousei Ito
Drug Metabolism and Disposition November 1, 2015, 43 (11) 1760-1768; DOI: https://doi.org/10.1124/dmd.115.065425
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