Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn
Research ArticleArticle

Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists

Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
Drug Metabolism and Disposition November 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Albert Braeuning
Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Maria Thomas
Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ute Hofmann
Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Silvia Vetter
Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Eva Zeller
Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Barbara Petzuch
Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Janina Johänning
Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Werner Schroth
Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Thomas S. Weiss
Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ulrich M. Zanger
Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Michael Schwarz
Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF
Loading

Article Information

vol. 43 no. 11 1781-1787
DOI 
https://doi.org/10.1124/dmd.115.064667
PubMed 
26310804

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 19, 2015
  • Accepted August 24, 2015
  • Published online October 12, 2015.

Article Versions

  • Earlier version (August 26, 2015 - 07:25).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Albert Braeuning,
  2. Maria Thomas,
  3. Ute Hofmann,
  4. Silvia Vetter,
  5. Eva Zeller,
  6. Barbara Petzuch,
  7. Janina Johänning,
  8. Werner Schroth,
  9. Thomas S. Weiss,
  10. Ulrich M. Zanger, and
  11. Michael Schwarz
  1. Department of Food Safety, Federal Institute for Risk Assessment, Berlin, Germany (A.B.); Dr.-Margarethe-Fischer-Bosch-Institute for Clinical Pharmacology, Stuttgart, and University of Tübingen, Tübingen, Germany (M.T., U.H., J.J., W.S., U.M.Z.); Department of Toxicology, Institute of Experimental and Clinical Pharmacology and Toxicology, Tübingen, Germany (A.B., S.V., E.Z., B.P., M.S.); Regensburg University Hospital, Regensburg, Germany (T.S.W.)
  1. Address correspondence to:
    Dr. Albert Braeuning, Federal Institute for Risk Assessment, Dept. Food Safety, Max-Dohrn-Str. 8-10, 10589 Berlin, Germany. E-mail: Albert.Braeuning{at}bfr.bund.de
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: August 2017 to March 2023

AbstractFullPdf
Aug 2017102635
Sep 2017411232
Oct 20171010317
Nov 2017132826
Dec 2017113120
Jan 2018102712
Feb 2018142429
Mar 201892014
Apr 2018102622
May 201872013
Jun 201872510
Jul 201861513
Aug 201872017
Sep 201881510
Oct 20180189
Nov 201861916
Dec 20183523
Jan 201931428
Feb 201982029
Mar 20193822
Apr 201951138
May 20191919
Jun 201941227
Jul 201921225
Aug 201991339
Oct 201901226
Nov 201941837
Dec 201931624
Jan 202051123
Feb 202011734
Mar 202061443
May 20201912
Jun 20200167
Jul 20200123
Aug 20202129
Sep 20207158
Oct 202011612
Nov 202011618
Dec 202091222
Jan 202171711
Feb 202151516
Mar 202191125
Apr 202144415
May 2021216119
Jun 20217724
Jul 202189329
Aug 2021841119
Sep 202101310
Oct 202144419
Nov 20215332
Dec 20211512
Jan 20223216
Feb 20221713
Mar 20221921
Apr 20224317
May 20224815
Jun 20225616
Jul 202238221
Aug 20223444
Sep 20222910
Oct 20222641
Nov 20222828
Dec 20221848
Jan 20233120
Feb 20231626
Mar 20231021

PreviousNext
Back to top

In this issue

Drug Metabolism and Disposition: 43 (11)
Drug Metabolism and Disposition
Vol. 43, Issue 11
1 Nov 2015
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Drug Metabolism & Disposition article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Comparative Analysis and Functional Characterization of HC-AFW1 Hepatocarcinoma Cells: Cytochrome P450 Expression and Induction by Nuclear Receptor Agonists
(Your Name) has forwarded a page to you from Drug Metabolism & Disposition
(Your Name) thought you would be interested in this article in Drug Metabolism & Disposition.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleArticle

Induction of Drug Metabolism in HC-AFW1 Cells

Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
Drug Metabolism and Disposition November 1, 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Research ArticleArticle

Induction of Drug Metabolism in HC-AFW1 Cells

Albert Braeuning, Maria Thomas, Ute Hofmann, Silvia Vetter, Eva Zeller, Barbara Petzuch, Janina Johänning, Werner Schroth, Thomas S. Weiss, Ulrich M. Zanger and Michael Schwarz
Drug Metabolism and Disposition November 1, 2015, 43 (11) 1781-1787; DOI: https://doi.org/10.1124/dmd.115.064667
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF + SI
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • Olanzapine Glucuronidation in Humanized Mice
  • rs2242480 Regulates the Expression of CYP3A4 and CYP3A5
  • Absorption, Metabolism, and Excretion of Taselisib
Show more Articles

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics