Research ArticleArticle
Rosuvastatin Liver Partitioning in Cynomolgus Monkeys: Measurement In Vivo and Prediction Using In Vitro Monkey Hepatocyte Uptake
Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
Drug Metabolism and Disposition November 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Bridget L. Morse
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Hong Cai
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Jamus G. MacGuire
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Maxine Fox
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Lisa Zhang
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Yueping Zhang
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Xiaomei Gu
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Hong Shen
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Elizabeth A. Dierks
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Hong Su
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Chiuwa E. Luk
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Punit Marathe
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Yue-Zhong Shu
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
W. Griffith Humphreys
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
Yurong Lai
Pharmaceutical Candidate Optimization (B.L.M., H.C., L.Z., Y.Z., X.G., H.S., E.A.D., H.S., C.E.L., P.M., Y-Z.S., W.G.H., Y.L.) and Veterinary Sciences, Bristol-Myers Squibb, Princeton, New Jersey (J.G.M., M.F.)
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Research ArticleArticle
Prediction of Rosuvastatin Liver Partitioning in Monkeys
Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
Drug Metabolism and Disposition November 1, 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
Research ArticleArticle
Prediction of Rosuvastatin Liver Partitioning in Monkeys
Bridget L. Morse, Hong Cai, Jamus G. MacGuire, Maxine Fox, Lisa Zhang, Yueping Zhang, Xiaomei Gu, Hong Shen, Elizabeth A. Dierks, Hong Su, Chiuwa E. Luk, Punit Marathe, Yue-Zhong Shu, W. Griffith Humphreys and Yurong Lai
Drug Metabolism and Disposition November 1, 2015, 43 (11) 1788-1794; DOI: https://doi.org/10.1124/dmd.115.065946
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