Skip to main content
Advertisement

Main menu

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET

User menu

  • My alerts
  • Log in
  • My Cart

Search

  • Advanced search
Drug Metabolism & Disposition
  • Other Publications
    • Drug Metabolism and Disposition
    • Journal of Pharmacology and Experimental Therapeutics
    • Molecular Pharmacology
    • Pharmacological Reviews
    • Pharmacology Research & Perspectives
    • ASPET
  • My alerts
  • Log in
  • My Cart
Drug Metabolism & Disposition

Advanced Search

  • Home
  • Articles
    • Current Issue
    • Fast Forward
    • Latest Articles
    • Special Sections
    • Archive
  • Information
    • Instructions to Authors
    • Submit a Manuscript
    • FAQs
    • For Subscribers
    • Terms & Conditions of Use
    • Permissions
  • Editorial Board
  • Alerts
    • Alerts
    • RSS Feeds
  • Virtual Issues
  • Feedback
  • Submit
  • Visit dmd on Facebook
  • Follow dmd on Twitter
  • Follow ASPET on LinkedIn
Research ArticleArticle

Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study

Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
Li Liu
Department of Pharmaceutics (L.L., P.H., A.K.D., J.D.U.), Department of Medicine (A.C.C.), Division of Nuclear Medicine (J.M.L., D.A.M., J.F.E.), Department of Anesthesiology and Pain Medicine (K.B.D.), and Department of Oral Health Sciences (C.F.S.), University of Washington, Seattle, Washington
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Ann C. Collier
Department of Pharmaceutics (L.L., P.H., A.K.D., J.D.U.), Department of Medicine (A.C.C.), Division of Nuclear Medicine (J.M.L., D.A.M., J.F.E.), Department of Anesthesiology and Pain Medicine (K.B.D.), and Department of Oral Health Sciences (C.F.S.), University of Washington, Seattle, Washington
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jeanne M. Link
Department of Pharmaceutics (L.L., P.H., A.K.D., J.D.U.), Department of Medicine (A.C.C.), Division of Nuclear Medicine (J.M.L., D.A.M., J.F.E.), Department of Anesthesiology and Pain Medicine (K.B.D.), and Department of Oral Health Sciences (C.F.S.), University of Washington, Seattle, Washington
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Karen B. Domino
Department of Pharmaceutics (L.L., P.H., A.K.D., J.D.U.), Department of Medicine (A.C.C.), Division of Nuclear Medicine (J.M.L., D.A.M., J.F.E.), Department of Anesthesiology and Pain Medicine (K.B.D.), and Department of Oral Health Sciences (C.F.S.), University of Washington, Seattle, Washington
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
David A. Mankoff
Department of Pharmaceutics (L.L., P.H., A.K.D., J.D.U.), Department of Medicine (A.C.C.), Division of Nuclear Medicine (J.M.L., D.A.M., J.F.E.), Department of Anesthesiology and Pain Medicine (K.B.D.), and Department of Oral Health Sciences (C.F.S.), University of Washington, Seattle, Washington
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Janet F. Eary
Department of Pharmaceutics (L.L., P.H., A.K.D., J.D.U.), Department of Medicine (A.C.C.), Division of Nuclear Medicine (J.M.L., D.A.M., J.F.E.), Department of Anesthesiology and Pain Medicine (K.B.D.), and Department of Oral Health Sciences (C.F.S.), University of Washington, Seattle, Washington
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Charles F. Spiekerman
Department of Pharmaceutics (L.L., P.H., A.K.D., J.D.U.), Department of Medicine (A.C.C.), Division of Nuclear Medicine (J.M.L., D.A.M., J.F.E.), Department of Anesthesiology and Pain Medicine (K.B.D.), and Department of Oral Health Sciences (C.F.S.), University of Washington, Seattle, Washington
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Peng Hsiao
Department of Pharmaceutics (L.L., P.H., A.K.D., J.D.U.), Department of Medicine (A.C.C.), Division of Nuclear Medicine (J.M.L., D.A.M., J.F.E.), Department of Anesthesiology and Pain Medicine (K.B.D.), and Department of Oral Health Sciences (C.F.S.), University of Washington, Seattle, Washington
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Anand K. Deo
Department of Pharmaceutics (L.L., P.H., A.K.D., J.D.U.), Department of Medicine (A.C.C.), Division of Nuclear Medicine (J.M.L., D.A.M., J.F.E.), Department of Anesthesiology and Pain Medicine (K.B.D.), and Department of Oral Health Sciences (C.F.S.), University of Washington, Seattle, Washington
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
Jashvant D. Unadkat
Department of Pharmaceutics (L.L., P.H., A.K.D., J.D.U.), Department of Medicine (A.C.C.), Division of Nuclear Medicine (J.M.L., D.A.M., J.F.E.), Department of Anesthesiology and Pain Medicine (K.B.D.), and Department of Oral Health Sciences (C.F.S.), University of Washington, Seattle, Washington
  • Find this author on Google Scholar
  • Find this author on PubMed
  • Search for this author on this site
  • Article
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF
Loading

 

DMD articles become freely available 12 months after publication, and remain freely available for 5 years. 

Non-open access articles that fall outside this five year window are available only to institutional subscribers and current ASPET members, or through the article purchase feature at the bottom of the page. 

 

  • Click here for information on institutional subscriptions.
  • Click here for information on individual ASPET membership.

 

Log in using your username and password

Forgot your user name or password?

Purchase access

You may purchase access to this article. This will require you to create an account if you don't already have one.
PreviousNext
Back to top

In this issue

Drug Metabolism and Disposition: 43 (11)
Drug Metabolism and Disposition
Vol. 43, Issue 11
1 Nov 2015
  • Table of Contents
  • Table of Contents (PDF)
  • About the Cover
  • Index by author
  • Editorial Board (PDF)
  • Front Matter (PDF)
Download PDF
Article Alerts
Sign In to Email Alerts with your Email Address
Email Article

Thank you for sharing this Drug Metabolism & Disposition article.

NOTE: We request your email address only to inform the recipient that it was you who recommended this article, and that it is not junk mail. We do not retain these email addresses.

Enter multiple addresses on separate lines or separate them with commas.
Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study
(Your Name) has forwarded a page to you from Drug Metabolism & Disposition
(Your Name) thought you would be interested in this article in Drug Metabolism & Disposition.
CAPTCHA
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Citation Tools
Research ArticleArticle

Modulation of Human BBB P-gp by Quinidine or Rifampin via PET Imaging

Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
Drug Metabolism and Disposition November 1, 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

Citation Manager Formats

  • BibTeX
  • Bookends
  • EasyBib
  • EndNote (tagged)
  • EndNote 8 (xml)
  • Medlars
  • Mendeley
  • Papers
  • RefWorks Tagged
  • Ref Manager
  • RIS
  • Zotero

Share
Research ArticleArticle

Modulation of Human BBB P-gp by Quinidine or Rifampin via PET Imaging

Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat
Drug Metabolism and Disposition November 1, 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685
Reddit logo Twitter logo Facebook logo Mendeley logo
  • Tweet Widget
  • Facebook Like
  • Google Plus One

Jump to section

  • Article
    • Abstract
    • Introduction
    • Materials and Methods
    • Results
    • Discussion
    • Acknowledgments
    • Authorship Contributions
    • Footnotes
    • Abbreviations
    • References
  • Figures & Data
  • Info & Metrics
  • eLetters
  • PDF

Related Articles

Cited By...

More in this TOC Section

  • CYP3A-mediated oxidation of DABE and BIBR0951
  • Adipocyte PXR does not play an essential role in obesity.
  • Biodistribution of Lipid in Rats
Show more Articles

Similar Articles

Advertisement
  • Home
  • Alerts
Facebook   Twitter   LinkedIn   RSS

Navigate

  • Current Issue
  • Fast Forward by date
  • Fast Forward by section
  • Latest Articles
  • Archive
  • Search for Articles
  • Feedback
  • ASPET

More Information

  • About DMD
  • Editorial Board
  • Instructions to Authors
  • Submit a Manuscript
  • Customized Alerts
  • RSS Feeds
  • Subscriptions
  • Permissions
  • Terms & Conditions of Use

ASPET's Other Journals

  • Journal of Pharmacology and Experimental Therapeutics
  • Molecular Pharmacology
  • Pharmacological Reviews
  • Pharmacology Research & Perspectives
ISSN 1521-009X (Online)

Copyright © 2023 by the American Society for Pharmacology and Experimental Therapeutics