Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study

Li Liu; Ann C. Collier; Jeanne M. Link; Karen B. Domino; David A. Mankoff; Janet F. Eary; Charles F. Spiekerman; Peng Hsiao; Anand K. Deo; Jashvant D. Unadkat

doi:10.1124/dmd.114.058685

Research ArticleArticle

Modulation of P-glycoprotein at the Human Blood-Brain Barrier by Quinidine or Rifampin Treatment: A Positron Emission Tomography Imaging Study

Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat

Drug Metabolism and Disposition November 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

Li Liu

Department of Pharmaceutics (L.L., P.H., A.K.D., J.D.U.), Department of Medicine (A.C.C.), Division of Nuclear Medicine (J.M.L., D.A.M., J.F.E.), Department of Anesthesiology and Pain Medicine (K.B.D.), and Department of Oral Health Sciences (C.F.S.), University of Washington, Seattle, Washington

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Ann C. Collier

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Jeanne M. Link

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Karen B. Domino

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David A. Mankoff

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Janet F. Eary

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Charles F. Spiekerman

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Peng Hsiao

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Anand K. Deo

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Jashvant D. Unadkat

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Drug Metabolism and Disposition

Vol. 43, Issue 11

1 Nov 2015

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Research ArticleArticle

Modulation of Human BBB P-gp by Quinidine or Rifampin via PET Imaging

Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat

Drug Metabolism and Disposition November 1, 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

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Research ArticleArticle

Modulation of Human BBB P-gp by Quinidine or Rifampin via PET Imaging

Li Liu, Ann C. Collier, Jeanne M. Link, Karen B. Domino, David A. Mankoff, Janet F. Eary, Charles F. Spiekerman, Peng Hsiao, Anand K. Deo and Jashvant D. Unadkat

Drug Metabolism and Disposition November 1, 2015, 43 (11) 1795-1804; DOI: https://doi.org/10.1124/dmd.114.058685

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