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Cover Caption

About the cover: The contour maps with compounds 20 and 6. See the article by Salminen et al. (dx.doi.org/10.1124/dmd.115.065755).

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Drug Metabolism and Disposition: 43 (12)

Drug Metabolism and Disposition

Vol. 43, Issue 12

1 Dec 2015

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Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUC_I/AUC) RATIOS
In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model

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