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Index by author

December 01, 2015; Volume 43,Issue 12

A

  1. Abagyan, Ruben

    1. Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors
      Wei Wu, Kevin T. Bush, Henry C. Liu, Christopher Zhu, Ruben Abagyan and Sanjay K. Nigam
      Drug Metabolism and Disposition December 2015, 43 (12) 1855-1863; DOI: https://doi.org/10.1124/dmd.115.065250

  2. Anderson, Shelby R.

    1. Low-Turnover Drug Molecules: A Current Challenge for Drug Metabolism Scientists
      J. Matthew Hutzler, Barbara J. Ring and Shelby R. Anderson
      Drug Metabolism and Disposition December 2015, 43 (12) 1917-1928; DOI: https://doi.org/10.1124/dmd.115.066431

B

  1. Baumgart, Joachim

    1. Penetration of Treosulfan and its Active Monoepoxide Transformation Product into Central Nervous System of Juvenile and Young Adult Rats
      Michał Romański, Joachim Baumgart, Sonja Böhm and Franciszek K. Główka
      Drug Metabolism and Disposition December 2015, 43 (12) 1946-1954; DOI: https://doi.org/10.1124/dmd.115.066050

  2. Berrigan, Liam

    1. Organic Anion Transporter 1 Is Inhibited by Multiple Mechanisms and Shows a Transport Mode Independent of Exchange
      Adam G. Hotchkiss, Tiandai Gao, Usman Khan, Liam Berrigan, Mansong Li, Leslie Ingraham and Ryan M. Pelis
      Drug Metabolism and Disposition December 2015, 43 (12) 1847-1854; DOI: https://doi.org/10.1124/dmd.115.065748

  3. Bodnar, Wanda M.

    1. Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family
      Matthew J. Fay, My Trang Nguyen, John N. Snouwaert, Rebecca Dye, Delores J. Grant, Wanda M. Bodnar and Beverly H. Koller
      Drug Metabolism and Disposition December 2015, 43 (12) 1838-1846; DOI: https://doi.org/10.1124/dmd.115.065482

  4. Böhm, Sonja

    1. Penetration of Treosulfan and its Active Monoepoxide Transformation Product into Central Nervous System of Juvenile and Young Adult Rats
      Michał Romański, Joachim Baumgart, Sonja Böhm and Franciszek K. Główka
      Drug Metabolism and Disposition December 2015, 43 (12) 1946-1954; DOI: https://doi.org/10.1124/dmd.115.066050

  5. Boily, Marc-Olivier

    1. In Vitro and In Vivo Mechanistic Studies toward Understanding the Role of 1-Aminobenzotriazole in Rat Drug-Drug Interactions
      Marc-Olivier Boily, Nathalie Chauret, Julie Laterreur, François A. Leblond, Chantal Boudreau, Marie-Claude Duquet, Jean-François Lévesque, Line Ste-Marie and Vincent Pichette
      Drug Metabolism and Disposition December 2015, 43 (12) 1960-1965; DOI: https://doi.org/10.1124/dmd.115.066357

  6. Boudreau, Chantal

    1. In Vitro and In Vivo Mechanistic Studies toward Understanding the Role of 1-Aminobenzotriazole in Rat Drug-Drug Interactions
      Marc-Olivier Boily, Nathalie Chauret, Julie Laterreur, François A. Leblond, Chantal Boudreau, Marie-Claude Duquet, Jean-François Lévesque, Line Ste-Marie and Vincent Pichette
      Drug Metabolism and Disposition December 2015, 43 (12) 1960-1965; DOI: https://doi.org/10.1124/dmd.115.066357

  7. Burns, Kushari

    1. The Nonspecific Binding of Tyrosine Kinase Inhibitors to Human Liver Microsomes
      Kushari Burns, Pramod C. Nair, Andrew Rowland, Peter I. Mackenzie, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition December 2015, 43 (12) 1934-1937; DOI: https://doi.org/10.1124/dmd.115.065292

  8. Bush, Kevin T.

    1. Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors
      Wei Wu, Kevin T. Bush, Henry C. Liu, Christopher Zhu, Ruben Abagyan and Sanjay K. Nigam
      Drug Metabolism and Disposition December 2015, 43 (12) 1855-1863; DOI: https://doi.org/10.1124/dmd.115.065250

C

  1. Cardoso, Josiane de Oliveira

    1. In Vitro Metabolism of Montelukast by Cytochrome P450s and UDP-Glucuronosyltransferases
      Josiane de Oliveira Cardoso, Regina Vincenzi Oliveira, Jessica Bo Li Lu and Zeruesenay Desta
      Drug Metabolism and Disposition December 2015, 43 (12) 1905-1916; DOI: https://doi.org/10.1124/dmd.115.065763

  2. Chauret, Nathalie

    1. In Vitro and In Vivo Mechanistic Studies toward Understanding the Role of 1-Aminobenzotriazole in Rat Drug-Drug Interactions
      Marc-Olivier Boily, Nathalie Chauret, Julie Laterreur, François A. Leblond, Chantal Boudreau, Marie-Claude Duquet, Jean-François Lévesque, Line Ste-Marie and Vincent Pichette
      Drug Metabolism and Disposition December 2015, 43 (12) 1960-1965; DOI: https://doi.org/10.1124/dmd.115.066357

  3. Choo, Edna F.

    1. Elucidating the Mechanisms of Formation for Two Unusual Cytochrome P450–Mediated Fused Ring Metabolites of GDC-0623, a MAPK/ERK Kinase Inhibitor
      Ryan H. Takahashi, Shuguang Ma, Sarah J. Robinson, Qin Yue, Edna F. Choo and S. Cyrus Khojasteh
      Drug Metabolism and Disposition December 2015, 43 (12) 1929-1933; DOI: https://doi.org/10.1124/dmd.115.067181

  4. Croy, Johnny E.

    1. Insights into the Impact of Heterogeneous Glycosylation on the Pharmacokinetic Behavior of Follistatin-Fc–Based Biotherapeutics
      Amita Datta-Mannan, Lihua Huang, Jennifer Pereira, Benjamin Yaden, Andrew Korytko and Johnny E. Croy
      Drug Metabolism and Disposition December 2015, 43 (12) 1882-1890; DOI: https://doi.org/10.1124/dmd.115.064519

D

  1. Datta-Mannan, Amita

    1. Insights into the Impact of Heterogeneous Glycosylation on the Pharmacokinetic Behavior of Follistatin-Fc–Based Biotherapeutics
      Amita Datta-Mannan, Lihua Huang, Jennifer Pereira, Benjamin Yaden, Andrew Korytko and Johnny E. Croy
      Drug Metabolism and Disposition December 2015, 43 (12) 1882-1890; DOI: https://doi.org/10.1124/dmd.115.064519

  2. Desta, Zeruesenay

    1. In Vitro Metabolism of Montelukast by Cytochrome P450s and UDP-Glucuronosyltransferases
      Josiane de Oliveira Cardoso, Regina Vincenzi Oliveira, Jessica Bo Li Lu and Zeruesenay Desta
      Drug Metabolism and Disposition December 2015, 43 (12) 1905-1916; DOI: https://doi.org/10.1124/dmd.115.065763

  3. Duan, Haichuan

    1. Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins
      Jia Yin, Haichuan Duan, Yoshiyuki Shirasaka, Bhagwat Prasad and Joanne Wang
      Drug Metabolism and Disposition December 2015, 43 (12) 1872-1881; DOI: https://doi.org/10.1124/dmd.115.066175

  4. Duquet, Marie-Claude

    1. In Vitro and In Vivo Mechanistic Studies toward Understanding the Role of 1-Aminobenzotriazole in Rat Drug-Drug Interactions
      Marc-Olivier Boily, Nathalie Chauret, Julie Laterreur, François A. Leblond, Chantal Boudreau, Marie-Claude Duquet, Jean-François Lévesque, Line Ste-Marie and Vincent Pichette
      Drug Metabolism and Disposition December 2015, 43 (12) 1960-1965; DOI: https://doi.org/10.1124/dmd.115.066357

  5. Dye, Rebecca

    1. Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family
      Matthew J. Fay, My Trang Nguyen, John N. Snouwaert, Rebecca Dye, Delores J. Grant, Wanda M. Bodnar and Beverly H. Koller
      Drug Metabolism and Disposition December 2015, 43 (12) 1838-1846; DOI: https://doi.org/10.1124/dmd.115.065482

F

  1. Fay, Matthew J.

    1. Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family
      Matthew J. Fay, My Trang Nguyen, John N. Snouwaert, Rebecca Dye, Delores J. Grant, Wanda M. Bodnar and Beverly H. Koller
      Drug Metabolism and Disposition December 2015, 43 (12) 1838-1846; DOI: https://doi.org/10.1124/dmd.115.065482

  2. Fujii, Shinobu

    1. Functional Characterization of Carrier-Mediated Transport of Pravastatin across the Blood-Retinal Barrier in Rats
      Shinobu Fujii, Chikako Setoguchi, Kouichi Kawazu and Ken-ichi Hosoya
      Drug Metabolism and Disposition December 2015, 43 (12) 1956-1959; DOI: https://doi.org/10.1124/dmd.115.066266

G

  1. Gao, Tiandai

    1. Organic Anion Transporter 1 Is Inhibited by Multiple Mechanisms and Shows a Transport Mode Independent of Exchange
      Adam G. Hotchkiss, Tiandai Gao, Usman Khan, Liam Berrigan, Mansong Li, Leslie Ingraham and Ryan M. Pelis
      Drug Metabolism and Disposition December 2015, 43 (12) 1847-1854; DOI: https://doi.org/10.1124/dmd.115.065748

  2. Główka, Franciszek K.

    1. Penetration of Treosulfan and its Active Monoepoxide Transformation Product into Central Nervous System of Juvenile and Young Adult Rats
      Michał Romański, Joachim Baumgart, Sonja Böhm and Franciszek K. Główka
      Drug Metabolism and Disposition December 2015, 43 (12) 1946-1954; DOI: https://doi.org/10.1124/dmd.115.066050

  3. Grant, Delores J.

    1. Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family
      Matthew J. Fay, My Trang Nguyen, John N. Snouwaert, Rebecca Dye, Delores J. Grant, Wanda M. Bodnar and Beverly H. Koller
      Drug Metabolism and Disposition December 2015, 43 (12) 1838-1846; DOI: https://doi.org/10.1124/dmd.115.065482

H

  1. Horling, Aline

    1. Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis
      Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
      Drug Metabolism and Disposition December 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755

  2. Hosoya, Ken-ichi

    1. Functional Characterization of Carrier-Mediated Transport of Pravastatin across the Blood-Retinal Barrier in Rats
      Shinobu Fujii, Chikako Setoguchi, Kouichi Kawazu and Ken-ichi Hosoya
      Drug Metabolism and Disposition December 2015, 43 (12) 1956-1959; DOI: https://doi.org/10.1124/dmd.115.066266

  3. Hotchkiss, Adam G.

    1. Organic Anion Transporter 1 Is Inhibited by Multiple Mechanisms and Shows a Transport Mode Independent of Exchange
      Adam G. Hotchkiss, Tiandai Gao, Usman Khan, Liam Berrigan, Mansong Li, Leslie Ingraham and Ryan M. Pelis
      Drug Metabolism and Disposition December 2015, 43 (12) 1847-1854; DOI: https://doi.org/10.1124/dmd.115.065748

  4. Huang, Lihua

    1. Insights into the Impact of Heterogeneous Glycosylation on the Pharmacokinetic Behavior of Follistatin-Fc–Based Biotherapeutics
      Amita Datta-Mannan, Lihua Huang, Jennifer Pereira, Benjamin Yaden, Andrew Korytko and Johnny E. Croy
      Drug Metabolism and Disposition December 2015, 43 (12) 1882-1890; DOI: https://doi.org/10.1124/dmd.115.064519

  5. Hutzler, J. Matthew

    1. Low-Turnover Drug Molecules: A Current Challenge for Drug Metabolism Scientists
      J. Matthew Hutzler, Barbara J. Ring and Shelby R. Anderson
      Drug Metabolism and Disposition December 2015, 43 (12) 1917-1928; DOI: https://doi.org/10.1124/dmd.115.066431

I

  1. Imming, Peter

    1. Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis
      Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
      Drug Metabolism and Disposition December 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755

  2. Ingraham, Leslie

    1. Organic Anion Transporter 1 Is Inhibited by Multiple Mechanisms and Shows a Transport Mode Independent of Exchange
      Adam G. Hotchkiss, Tiandai Gao, Usman Khan, Liam Berrigan, Mansong Li, Leslie Ingraham and Ryan M. Pelis
      Drug Metabolism and Disposition December 2015, 43 (12) 1847-1854; DOI: https://doi.org/10.1124/dmd.115.065748

J

  1. Jiang, Weiwu

    1. Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor
      Ananddeep Patel, Shaojie Zhang, Maturu Paramahamsa, Weiwu Jiang, Lihua Wang, Bhagavatula Moorthy and Binoy Shivanna
      Drug Metabolism and Disposition December 2015, 43 (12) 1966-1970; DOI: https://doi.org/10.1124/dmd.115.066084

K

  1. Kawazu, Kouichi

    1. Functional Characterization of Carrier-Mediated Transport of Pravastatin across the Blood-Retinal Barrier in Rats
      Shinobu Fujii, Chikako Setoguchi, Kouichi Kawazu and Ken-ichi Hosoya
      Drug Metabolism and Disposition December 2015, 43 (12) 1956-1959; DOI: https://doi.org/10.1124/dmd.115.066266

  2. Khan, Usman

    1. Organic Anion Transporter 1 Is Inhibited by Multiple Mechanisms and Shows a Transport Mode Independent of Exchange
      Adam G. Hotchkiss, Tiandai Gao, Usman Khan, Liam Berrigan, Mansong Li, Leslie Ingraham and Ryan M. Pelis
      Drug Metabolism and Disposition December 2015, 43 (12) 1847-1854; DOI: https://doi.org/10.1124/dmd.115.065748

  3. Khojasteh, S. Cyrus

    1. Elucidating the Mechanisms of Formation for Two Unusual Cytochrome P450–Mediated Fused Ring Metabolites of GDC-0623, a MAPK/ERK Kinase Inhibitor
      Ryan H. Takahashi, Shuguang Ma, Sarah J. Robinson, Qin Yue, Edna F. Choo and S. Cyrus Khojasteh
      Drug Metabolism and Disposition December 2015, 43 (12) 1929-1933; DOI: https://doi.org/10.1124/dmd.115.067181

  4. Knights, Kathleen M.

    1. The Nonspecific Binding of Tyrosine Kinase Inhibitors to Human Liver Microsomes
      Kushari Burns, Pramod C. Nair, Andrew Rowland, Peter I. Mackenzie, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition December 2015, 43 (12) 1934-1937; DOI: https://doi.org/10.1124/dmd.115.065292

  5. Koller, Beverly H.

    1. Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family
      Matthew J. Fay, My Trang Nguyen, John N. Snouwaert, Rebecca Dye, Delores J. Grant, Wanda M. Bodnar and Beverly H. Koller
      Drug Metabolism and Disposition December 2015, 43 (12) 1838-1846; DOI: https://doi.org/10.1124/dmd.115.065482

  6. Korytko, Andrew

    1. Insights into the Impact of Heterogeneous Glycosylation on the Pharmacokinetic Behavior of Follistatin-Fc–Based Biotherapeutics
      Amita Datta-Mannan, Lihua Huang, Jennifer Pereira, Benjamin Yaden, Andrew Korytko and Johnny E. Croy
      Drug Metabolism and Disposition December 2015, 43 (12) 1882-1890; DOI: https://doi.org/10.1124/dmd.115.064519

  7. Kraemer, Thomas

    1. Chiral Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine and its Phase I and II Metabolites following Controlled Administration to Humans
      Andrea E. Steuer, Corina Schmidhauser, Yasmin Schmid, Anna Rickli, Matthias E. Liechti and Thomas Kraemer
      Drug Metabolism and Disposition December 2015, 43 (12) 1864-1871; DOI: https://doi.org/10.1124/dmd.115.066340

L

  1. Lahtela-Kakkonen, Maija

    1. Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis
      Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
      Drug Metabolism and Disposition December 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755

  2. Laitinen, Tuomo

    1. Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis
      Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
      Drug Metabolism and Disposition December 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755

  3. Laterreur, Julie

    1. In Vitro and In Vivo Mechanistic Studies toward Understanding the Role of 1-Aminobenzotriazole in Rat Drug-Drug Interactions
      Marc-Olivier Boily, Nathalie Chauret, Julie Laterreur, François A. Leblond, Chantal Boudreau, Marie-Claude Duquet, Jean-François Lévesque, Line Ste-Marie and Vincent Pichette
      Drug Metabolism and Disposition December 2015, 43 (12) 1960-1965; DOI: https://doi.org/10.1124/dmd.115.066357

  4. Leblond, François A.

    1. In Vitro and In Vivo Mechanistic Studies toward Understanding the Role of 1-Aminobenzotriazole in Rat Drug-Drug Interactions
      Marc-Olivier Boily, Nathalie Chauret, Julie Laterreur, François A. Leblond, Chantal Boudreau, Marie-Claude Duquet, Jean-François Lévesque, Line Ste-Marie and Vincent Pichette
      Drug Metabolism and Disposition December 2015, 43 (12) 1960-1965; DOI: https://doi.org/10.1124/dmd.115.066357

  5. Lévesque, Jean-François

    1. In Vitro and In Vivo Mechanistic Studies toward Understanding the Role of 1-Aminobenzotriazole in Rat Drug-Drug Interactions
      Marc-Olivier Boily, Nathalie Chauret, Julie Laterreur, François A. Leblond, Chantal Boudreau, Marie-Claude Duquet, Jean-François Lévesque, Line Ste-Marie and Vincent Pichette
      Drug Metabolism and Disposition December 2015, 43 (12) 1960-1965; DOI: https://doi.org/10.1124/dmd.115.066357

  6. Li, Mansong

    1. Organic Anion Transporter 1 Is Inhibited by Multiple Mechanisms and Shows a Transport Mode Independent of Exchange
      Adam G. Hotchkiss, Tiandai Gao, Usman Khan, Liam Berrigan, Mansong Li, Leslie Ingraham and Ryan M. Pelis
      Drug Metabolism and Disposition December 2015, 43 (12) 1847-1854; DOI: https://doi.org/10.1124/dmd.115.065748

  7. Liechti, Matthias E.

    1. Chiral Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine and its Phase I and II Metabolites following Controlled Administration to Humans
      Andrea E. Steuer, Corina Schmidhauser, Yasmin Schmid, Anna Rickli, Matthias E. Liechti and Thomas Kraemer
      Drug Metabolism and Disposition December 2015, 43 (12) 1864-1871; DOI: https://doi.org/10.1124/dmd.115.066340

  8. Liu, Henry C.

    1. Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors
      Wei Wu, Kevin T. Bush, Henry C. Liu, Christopher Zhu, Ruben Abagyan and Sanjay K. Nigam
      Drug Metabolism and Disposition December 2015, 43 (12) 1855-1863; DOI: https://doi.org/10.1124/dmd.115.065250

  9. Liu, Ke

    1. Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver
      Yun-Chen Tien, Ke Liu, Chad Pope, Pengcheng Wang, Xiaochao Ma and Xiao-bo Zhong
      Drug Metabolism and Disposition December 2015, 43 (12) 1938-1945; DOI: https://doi.org/10.1124/dmd.115.066316

  10. Lu, Jessica Bo Li

    1. In Vitro Metabolism of Montelukast by Cytochrome P450s and UDP-Glucuronosyltransferases
      Josiane de Oliveira Cardoso, Regina Vincenzi Oliveira, Jessica Bo Li Lu and Zeruesenay Desta
      Drug Metabolism and Disposition December 2015, 43 (12) 1905-1916; DOI: https://doi.org/10.1124/dmd.115.065763

M

  1. Ma, Shuguang

    1. Elucidating the Mechanisms of Formation for Two Unusual Cytochrome P450–Mediated Fused Ring Metabolites of GDC-0623, a MAPK/ERK Kinase Inhibitor
      Ryan H. Takahashi, Shuguang Ma, Sarah J. Robinson, Qin Yue, Edna F. Choo and S. Cyrus Khojasteh
      Drug Metabolism and Disposition December 2015, 43 (12) 1929-1933; DOI: https://doi.org/10.1124/dmd.115.067181

  2. Ma, Xiaochao

    1. Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver
      Yun-Chen Tien, Ke Liu, Chad Pope, Pengcheng Wang, Xiaochao Ma and Xiao-bo Zhong
      Drug Metabolism and Disposition December 2015, 43 (12) 1938-1945; DOI: https://doi.org/10.1124/dmd.115.066316

  3. Mackenzie, Peter I.

    1. The Nonspecific Binding of Tyrosine Kinase Inhibitors to Human Liver Microsomes
      Kushari Burns, Pramod C. Nair, Andrew Rowland, Peter I. Mackenzie, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition December 2015, 43 (12) 1934-1937; DOI: https://doi.org/10.1124/dmd.115.065292

  4. Meyer, Achim

    1. Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis
      Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
      Drug Metabolism and Disposition December 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755

  5. Miners, John O.

    1. The Nonspecific Binding of Tyrosine Kinase Inhibitors to Human Liver Microsomes
      Kushari Burns, Pramod C. Nair, Andrew Rowland, Peter I. Mackenzie, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition December 2015, 43 (12) 1934-1937; DOI: https://doi.org/10.1124/dmd.115.065292

  6. Moorthy, Bhagavatula

    1. Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor
      Ananddeep Patel, Shaojie Zhang, Maturu Paramahamsa, Weiwu Jiang, Lihua Wang, Bhagavatula Moorthy and Binoy Shivanna
      Drug Metabolism and Disposition December 2015, 43 (12) 1966-1970; DOI: https://doi.org/10.1124/dmd.115.066084

N

  1. Nair, Pramod C.

    1. The Nonspecific Binding of Tyrosine Kinase Inhibitors to Human Liver Microsomes
      Kushari Burns, Pramod C. Nair, Andrew Rowland, Peter I. Mackenzie, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition December 2015, 43 (12) 1934-1937; DOI: https://doi.org/10.1124/dmd.115.065292

  2. Nguyen, My Trang

    1. Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family
      Matthew J. Fay, My Trang Nguyen, John N. Snouwaert, Rebecca Dye, Delores J. Grant, Wanda M. Bodnar and Beverly H. Koller
      Drug Metabolism and Disposition December 2015, 43 (12) 1838-1846; DOI: https://doi.org/10.1124/dmd.115.065482

  3. Nigam, Sanjay K.

    1. Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors
      Wei Wu, Kevin T. Bush, Henry C. Liu, Christopher Zhu, Ruben Abagyan and Sanjay K. Nigam
      Drug Metabolism and Disposition December 2015, 43 (12) 1855-1863; DOI: https://doi.org/10.1124/dmd.115.065250

O

  1. Oliveira, Regina Vincenzi

    1. In Vitro Metabolism of Montelukast by Cytochrome P450s and UDP-Glucuronosyltransferases
      Josiane de Oliveira Cardoso, Regina Vincenzi Oliveira, Jessica Bo Li Lu and Zeruesenay Desta
      Drug Metabolism and Disposition December 2015, 43 (12) 1905-1916; DOI: https://doi.org/10.1124/dmd.115.065763

P

  1. Paramahamsa, Maturu

    1. Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor
      Ananddeep Patel, Shaojie Zhang, Maturu Paramahamsa, Weiwu Jiang, Lihua Wang, Bhagavatula Moorthy and Binoy Shivanna
      Drug Metabolism and Disposition December 2015, 43 (12) 1966-1970; DOI: https://doi.org/10.1124/dmd.115.066084

  2. Patel, Ananddeep

    1. Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor
      Ananddeep Patel, Shaojie Zhang, Maturu Paramahamsa, Weiwu Jiang, Lihua Wang, Bhagavatula Moorthy and Binoy Shivanna
      Drug Metabolism and Disposition December 2015, 43 (12) 1966-1970; DOI: https://doi.org/10.1124/dmd.115.066084

  3. Pelis, Ryan M.

    1. Organic Anion Transporter 1 Is Inhibited by Multiple Mechanisms and Shows a Transport Mode Independent of Exchange
      Adam G. Hotchkiss, Tiandai Gao, Usman Khan, Liam Berrigan, Mansong Li, Leslie Ingraham and Ryan M. Pelis
      Drug Metabolism and Disposition December 2015, 43 (12) 1847-1854; DOI: https://doi.org/10.1124/dmd.115.065748

  4. Pereira, Jennifer

    1. Insights into the Impact of Heterogeneous Glycosylation on the Pharmacokinetic Behavior of Follistatin-Fc–Based Biotherapeutics
      Amita Datta-Mannan, Lihua Huang, Jennifer Pereira, Benjamin Yaden, Andrew Korytko and Johnny E. Croy
      Drug Metabolism and Disposition December 2015, 43 (12) 1882-1890; DOI: https://doi.org/10.1124/dmd.115.064519

  5. Pichette, Vincent

    1. In Vitro and In Vivo Mechanistic Studies toward Understanding the Role of 1-Aminobenzotriazole in Rat Drug-Drug Interactions
      Marc-Olivier Boily, Nathalie Chauret, Julie Laterreur, François A. Leblond, Chantal Boudreau, Marie-Claude Duquet, Jean-François Lévesque, Line Ste-Marie and Vincent Pichette
      Drug Metabolism and Disposition December 2015, 43 (12) 1960-1965; DOI: https://doi.org/10.1124/dmd.115.066357

  6. Pope, Chad

    1. Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver
      Yun-Chen Tien, Ke Liu, Chad Pope, Pengcheng Wang, Xiaochao Ma and Xiao-bo Zhong
      Drug Metabolism and Disposition December 2015, 43 (12) 1938-1945; DOI: https://doi.org/10.1124/dmd.115.066316

  7. Poso, Antti

    1. Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis
      Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
      Drug Metabolism and Disposition December 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755

  8. Prasad, Bhagwat

    1. Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins
      Jia Yin, Haichuan Duan, Yoshiyuki Shirasaka, Bhagwat Prasad and Joanne Wang
      Drug Metabolism and Disposition December 2015, 43 (12) 1872-1881; DOI: https://doi.org/10.1124/dmd.115.066175

R

  1. Rahnasto-Rilla, Minna

    1. Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis
      Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
      Drug Metabolism and Disposition December 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755

  2. Raunio, Hannu

    1. Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis
      Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
      Drug Metabolism and Disposition December 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755

  3. Rickli, Anna

    1. Chiral Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine and its Phase I and II Metabolites following Controlled Administration to Humans
      Andrea E. Steuer, Corina Schmidhauser, Yasmin Schmid, Anna Rickli, Matthias E. Liechti and Thomas Kraemer
      Drug Metabolism and Disposition December 2015, 43 (12) 1864-1871; DOI: https://doi.org/10.1124/dmd.115.066340

  4. Ring, Barbara J.

    1. Low-Turnover Drug Molecules: A Current Challenge for Drug Metabolism Scientists
      J. Matthew Hutzler, Barbara J. Ring and Shelby R. Anderson
      Drug Metabolism and Disposition December 2015, 43 (12) 1917-1928; DOI: https://doi.org/10.1124/dmd.115.066431

  5. Robinson, Sarah J.

    1. Elucidating the Mechanisms of Formation for Two Unusual Cytochrome P450–Mediated Fused Ring Metabolites of GDC-0623, a MAPK/ERK Kinase Inhibitor
      Ryan H. Takahashi, Shuguang Ma, Sarah J. Robinson, Qin Yue, Edna F. Choo and S. Cyrus Khojasteh
      Drug Metabolism and Disposition December 2015, 43 (12) 1929-1933; DOI: https://doi.org/10.1124/dmd.115.067181

  6. Romański, Michał

    1. Penetration of Treosulfan and its Active Monoepoxide Transformation Product into Central Nervous System of Juvenile and Young Adult Rats
      Michał Romański, Joachim Baumgart, Sonja Böhm and Franciszek K. Główka
      Drug Metabolism and Disposition December 2015, 43 (12) 1946-1954; DOI: https://doi.org/10.1124/dmd.115.066050

  7. Rowland, Andrew

    1. The Nonspecific Binding of Tyrosine Kinase Inhibitors to Human Liver Microsomes
      Kushari Burns, Pramod C. Nair, Andrew Rowland, Peter I. Mackenzie, Kathleen M. Knights and John O. Miners
      Drug Metabolism and Disposition December 2015, 43 (12) 1934-1937; DOI: https://doi.org/10.1124/dmd.115.065292

S

  1. Salminen, Kaisa A.

    1. Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis
      Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
      Drug Metabolism and Disposition December 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755

  2. Schmid, Yasmin

    1. Chiral Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine and its Phase I and II Metabolites following Controlled Administration to Humans
      Andrea E. Steuer, Corina Schmidhauser, Yasmin Schmid, Anna Rickli, Matthias E. Liechti and Thomas Kraemer
      Drug Metabolism and Disposition December 2015, 43 (12) 1864-1871; DOI: https://doi.org/10.1124/dmd.115.066340

  3. Schmidhauser, Corina

    1. Chiral Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine and its Phase I and II Metabolites following Controlled Administration to Humans
      Andrea E. Steuer, Corina Schmidhauser, Yasmin Schmid, Anna Rickli, Matthias E. Liechti and Thomas Kraemer
      Drug Metabolism and Disposition December 2015, 43 (12) 1864-1871; DOI: https://doi.org/10.1124/dmd.115.066340

  4. Setoguchi, Chikako

    1. Functional Characterization of Carrier-Mediated Transport of Pravastatin across the Blood-Retinal Barrier in Rats
      Shinobu Fujii, Chikako Setoguchi, Kouichi Kawazu and Ken-ichi Hosoya
      Drug Metabolism and Disposition December 2015, 43 (12) 1956-1959; DOI: https://doi.org/10.1124/dmd.115.066266

  5. Shirasaka, Yoshiyuki

    1. Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins
      Jia Yin, Haichuan Duan, Yoshiyuki Shirasaka, Bhagwat Prasad and Joanne Wang
      Drug Metabolism and Disposition December 2015, 43 (12) 1872-1881; DOI: https://doi.org/10.1124/dmd.115.066175

  6. Shivanna, Binoy

    1. Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor
      Ananddeep Patel, Shaojie Zhang, Maturu Paramahamsa, Weiwu Jiang, Lihua Wang, Bhagavatula Moorthy and Binoy Shivanna
      Drug Metabolism and Disposition December 2015, 43 (12) 1966-1970; DOI: https://doi.org/10.1124/dmd.115.066084

  7. Snouwaert, John N.

    1. Xenobiotic Metabolism in Mice Lacking the UDP-Glucuronosyltransferase 2 Family
      Matthew J. Fay, My Trang Nguyen, John N. Snouwaert, Rebecca Dye, Delores J. Grant, Wanda M. Bodnar and Beverly H. Koller
      Drug Metabolism and Disposition December 2015, 43 (12) 1838-1846; DOI: https://doi.org/10.1124/dmd.115.065482

  8. Ste-Marie, Line

    1. In Vitro and In Vivo Mechanistic Studies toward Understanding the Role of 1-Aminobenzotriazole in Rat Drug-Drug Interactions
      Marc-Olivier Boily, Nathalie Chauret, Julie Laterreur, François A. Leblond, Chantal Boudreau, Marie-Claude Duquet, Jean-François Lévesque, Line Ste-Marie and Vincent Pichette
      Drug Metabolism and Disposition December 2015, 43 (12) 1960-1965; DOI: https://doi.org/10.1124/dmd.115.066357

  9. Steuer, Andrea E.

    1. Chiral Plasma Pharmacokinetics of 3,4-Methylenedioxymethamphetamine and its Phase I and II Metabolites following Controlled Administration to Humans
      Andrea E. Steuer, Corina Schmidhauser, Yasmin Schmid, Anna Rickli, Matthias E. Liechti and Thomas Kraemer
      Drug Metabolism and Disposition December 2015, 43 (12) 1864-1871; DOI: https://doi.org/10.1124/dmd.115.066340

T

  1. Takahashi, Ryan H.

    1. Elucidating the Mechanisms of Formation for Two Unusual Cytochrome P450–Mediated Fused Ring Metabolites of GDC-0623, a MAPK/ERK Kinase Inhibitor
      Ryan H. Takahashi, Shuguang Ma, Sarah J. Robinson, Qin Yue, Edna F. Choo and S. Cyrus Khojasteh
      Drug Metabolism and Disposition December 2015, 43 (12) 1929-1933; DOI: https://doi.org/10.1124/dmd.115.067181

  2. Tien, Yun-Chen

    1. Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver
      Yun-Chen Tien, Ke Liu, Chad Pope, Pengcheng Wang, Xiaochao Ma and Xiao-bo Zhong
      Drug Metabolism and Disposition December 2015, 43 (12) 1938-1945; DOI: https://doi.org/10.1124/dmd.115.066316

V

  1. Väänänen, Raija

    1. Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis
      Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
      Drug Metabolism and Disposition December 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755

W

  1. Wang, Joanne

    1. Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins
      Jia Yin, Haichuan Duan, Yoshiyuki Shirasaka, Bhagwat Prasad and Joanne Wang
      Drug Metabolism and Disposition December 2015, 43 (12) 1872-1881; DOI: https://doi.org/10.1124/dmd.115.066175

  2. Wang, Lihua

    1. Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor
      Ananddeep Patel, Shaojie Zhang, Maturu Paramahamsa, Weiwu Jiang, Lihua Wang, Bhagavatula Moorthy and Binoy Shivanna
      Drug Metabolism and Disposition December 2015, 43 (12) 1966-1970; DOI: https://doi.org/10.1124/dmd.115.066084

  3. Wang, Pengcheng

    1. Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver
      Yun-Chen Tien, Ke Liu, Chad Pope, Pengcheng Wang, Xiaochao Ma and Xiao-bo Zhong
      Drug Metabolism and Disposition December 2015, 43 (12) 1938-1945; DOI: https://doi.org/10.1124/dmd.115.066316

  4. Wu, Wei

    1. Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors
      Wei Wu, Kevin T. Bush, Henry C. Liu, Christopher Zhu, Ruben Abagyan and Sanjay K. Nigam
      Drug Metabolism and Disposition December 2015, 43 (12) 1855-1863; DOI: https://doi.org/10.1124/dmd.115.065250

Y

  1. Yaden, Benjamin

    1. Insights into the Impact of Heterogeneous Glycosylation on the Pharmacokinetic Behavior of Follistatin-Fc–Based Biotherapeutics
      Amita Datta-Mannan, Lihua Huang, Jennifer Pereira, Benjamin Yaden, Andrew Korytko and Johnny E. Croy
      Drug Metabolism and Disposition December 2015, 43 (12) 1882-1890; DOI: https://doi.org/10.1124/dmd.115.064519

  2. Yin, Jia

    1. Atenolol Renal Secretion Is Mediated by Human Organic Cation Transporter 2 and Multidrug and Toxin Extrusion Proteins
      Jia Yin, Haichuan Duan, Yoshiyuki Shirasaka, Bhagwat Prasad and Joanne Wang
      Drug Metabolism and Disposition December 2015, 43 (12) 1872-1881; DOI: https://doi.org/10.1124/dmd.115.066175

  3. Yue, Qin

    1. Elucidating the Mechanisms of Formation for Two Unusual Cytochrome P450–Mediated Fused Ring Metabolites of GDC-0623, a MAPK/ERK Kinase Inhibitor
      Ryan H. Takahashi, Shuguang Ma, Sarah J. Robinson, Qin Yue, Edna F. Choo and S. Cyrus Khojasteh
      Drug Metabolism and Disposition December 2015, 43 (12) 1929-1933; DOI: https://doi.org/10.1124/dmd.115.067181

Z

  1. Zhang, Shaojie

    1. Leflunomide Induces Pulmonary and Hepatic CYP1A Enzymes via Aryl Hydrocarbon Receptor
      Ananddeep Patel, Shaojie Zhang, Maturu Paramahamsa, Weiwu Jiang, Lihua Wang, Bhagavatula Moorthy and Binoy Shivanna
      Drug Metabolism and Disposition December 2015, 43 (12) 1966-1970; DOI: https://doi.org/10.1124/dmd.115.066084

  2. Zhong, Xiao-bo

    1. Dose of Phenobarbital and Age of Treatment at Early Life are Two Key Factors for the Persistent Induction of Cytochrome P450 Enzymes in Adult Mouse Liver
      Yun-Chen Tien, Ke Liu, Chad Pope, Pengcheng Wang, Xiaochao Ma and Xiao-bo Zhong
      Drug Metabolism and Disposition December 2015, 43 (12) 1938-1945; DOI: https://doi.org/10.1124/dmd.115.066316

  3. Zhu, Christopher

    1. Shared Ligands Between Organic Anion Transporters (OAT1 and OAT6) and Odorant Receptors
      Wei Wu, Kevin T. Bush, Henry C. Liu, Christopher Zhu, Ruben Abagyan and Sanjay K. Nigam
      Drug Metabolism and Disposition December 2015, 43 (12) 1855-1863; DOI: https://doi.org/10.1124/dmd.115.065250
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