Research ArticleArticle
Time-Dependent Inhibition of CYP2C19 by Isoquinoline Alkaloids: In Vitro and In Silico Analysis
Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
Drug Metabolism and Disposition December 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755
Kaisa A. Salminen
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (K.A.S., M.R.-R., R.V., A.P., T.L., H.R., M.L.-K.); and Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany (P.I., A.M., A.H.)
Minna Rahnasto-Rilla
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (K.A.S., M.R.-R., R.V., A.P., T.L., H.R., M.L.-K.); and Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany (P.I., A.M., A.H.)
Raija Väänänen
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (K.A.S., M.R.-R., R.V., A.P., T.L., H.R., M.L.-K.); and Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany (P.I., A.M., A.H.)
Peter Imming
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (K.A.S., M.R.-R., R.V., A.P., T.L., H.R., M.L.-K.); and Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany (P.I., A.M., A.H.)
Achim Meyer
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (K.A.S., M.R.-R., R.V., A.P., T.L., H.R., M.L.-K.); and Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany (P.I., A.M., A.H.)
Aline Horling
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (K.A.S., M.R.-R., R.V., A.P., T.L., H.R., M.L.-K.); and Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany (P.I., A.M., A.H.)
Antti Poso
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (K.A.S., M.R.-R., R.V., A.P., T.L., H.R., M.L.-K.); and Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany (P.I., A.M., A.H.)
Tuomo Laitinen
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (K.A.S., M.R.-R., R.V., A.P., T.L., H.R., M.L.-K.); and Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany (P.I., A.M., A.H.)
Hannu Raunio
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (K.A.S., M.R.-R., R.V., A.P., T.L., H.R., M.L.-K.); and Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany (P.I., A.M., A.H.)
Maija Lahtela-Kakkonen
School of Pharmacy, Faculty of Health Sciences, University of Eastern Finland, Kuopio, Finland (K.A.S., M.R.-R., R.V., A.P., T.L., H.R., M.L.-K.); and Institut für Pharmazie, Martin-Luther-Universität Halle-Wittenberg, Halle, Germany (P.I., A.M., A.H.)
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Research ArticleArticle
3D-QSAR Model for CYP2C19 Inactivation by Plant Alkaloids
Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
Drug Metabolism and Disposition December 1, 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755
Research ArticleArticle
3D-QSAR Model for CYP2C19 Inactivation by Plant Alkaloids
Kaisa A. Salminen, Minna Rahnasto-Rilla, Raija Väänänen, Peter Imming, Achim Meyer, Aline Horling, Antti Poso, Tuomo Laitinen, Hannu Raunio and Maija Lahtela-Kakkonen
Drug Metabolism and Disposition December 1, 2015, 43 (12) 1891-1904; DOI: https://doi.org/10.1124/dmd.115.065755
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