Absorption, Metabolism, and Excretion of Oral 14C Radiolabeled Ibrutinib: An Open-Label, Phase I, Single-Dose Study in Healthy Men

Ellen Scheers; Laurent Leclercq; Jan de Jong; Nini Bode; Marc Bockx; Aline Laenen; Filip Cuyckens; Donna Skee; Joe Murphy; Juthamas Sukbuntherng; Geert Mannens

doi:10.1124/dmd.114.060061

Research ArticleArticle

Absorption, Metabolism, and Excretion of Oral ¹⁴C Radiolabeled Ibrutinib: An Open-Label, Phase I, Single-Dose Study in Healthy Men

Ellen Scheers, Laurent Leclercq, Jan de Jong, Nini Bode, Marc Bockx, Aline Laenen, Filip Cuyckens, Donna Skee, Joe Murphy, Juthamas Sukbuntherng and Geert Mannens

Drug Metabolism and Disposition February 2015, 43 (2) 289-297; DOI: https://doi.org/10.1124/dmd.114.060061

Ellen Scheers

Pharmacokinetics, Dynamics and Metabolism, Janssen R&D, Beerse, Belgium (E.S., L.L., M.B., A.L., F.C., G.M.); Clinical Pharmacology, Janssen R&D, San Diego, California (J.d.J.); Pre-Clinical Project Development, Janssen R&D, Beerse, Belgium (N.B.); Clinical Pharmacology, Janssen R&D, Raritan, New Jersey (D.S., J.M.); and Pharmacyclics, Sunnyvale, California (J.S.)

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Laurent Leclercq

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Jan de Jong

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Nini Bode

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Marc Bockx

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Aline Laenen

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Filip Cuyckens

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Donna Skee

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Joe Murphy

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Juthamas Sukbuntherng

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Geert Mannens

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Drug Metabolism and Disposition

Vol. 43, Issue 2

1 Feb 2015

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Research ArticleArticle

Absorption, Metabolism, and Excretion of Ibrutinib

Ellen Scheers, Laurent Leclercq, Jan de Jong, Nini Bode, Marc Bockx, Aline Laenen, Filip Cuyckens, Donna Skee, Joe Murphy, Juthamas Sukbuntherng and Geert Mannens

Drug Metabolism and Disposition February 1, 2015, 43 (2) 289-297; DOI: https://doi.org/10.1124/dmd.114.060061

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Research ArticleArticle

Absorption, Metabolism, and Excretion of Ibrutinib

Ellen Scheers, Laurent Leclercq, Jan de Jong, Nini Bode, Marc Bockx, Aline Laenen, Filip Cuyckens, Donna Skee, Joe Murphy, Juthamas Sukbuntherng and Geert Mannens

Drug Metabolism and Disposition February 1, 2015, 43 (2) 289-297; DOI: https://doi.org/10.1124/dmd.114.060061

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