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Research ArticleArticle

Mechanism-Based Inhibitory and Peroxisome Proliferator-Activated Receptor α–Dependent Modulating Effects of Silybin on Principal Hepatic Drug-Metabolizing Enzymes

Hong Wang, Tingting Yan, Yuan Xie, Min Zhao, Yuan Che, Jun Zhang, Huiying Liu, Lijuan Cao, Xuefang Cheng, Yang Xie, Feiyan Li, Qu Qi, Guangji Wang and Haiping Hao
Drug Metabolism and Disposition April 2015, 43 (4) 444-454; DOI: https://doi.org/10.1124/dmd.114.061622
Hong Wang
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Tingting Yan
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Yuan Xie
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Min Zhao
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Yuan Che
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Jun Zhang
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Huiying Liu
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Lijuan Cao
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Xuefang Cheng
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Yang Xie
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Feiyan Li
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Qu Qi
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Guangji Wang
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Haiping Hao
State Key Laboratory of Natural Medicines, Key Laboratory of Drug Metabolism and Pharmacokinetics, China Pharmaceutical University, Nanjing, China
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Drug Metabolism and Disposition: 43 (4)
Drug Metabolism and Disposition
Vol. 43, Issue 4
1 Apr 2015
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Research ArticleArticle

Regulatory Effects of Silybin on DMEs

Hong Wang, Tingting Yan, Yuan Xie, Min Zhao, Yuan Che, Jun Zhang, Huiying Liu, Lijuan Cao, Xuefang Cheng, Yang Xie, Feiyan Li, Qu Qi, Guangji Wang and Haiping Hao
Drug Metabolism and Disposition April 1, 2015, 43 (4) 444-454; DOI: https://doi.org/10.1124/dmd.114.061622

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Research ArticleArticle

Regulatory Effects of Silybin on DMEs

Hong Wang, Tingting Yan, Yuan Xie, Min Zhao, Yuan Che, Jun Zhang, Huiying Liu, Lijuan Cao, Xuefang Cheng, Yang Xie, Feiyan Li, Qu Qi, Guangji Wang and Haiping Hao
Drug Metabolism and Disposition April 1, 2015, 43 (4) 444-454; DOI: https://doi.org/10.1124/dmd.114.061622
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