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Research ArticleArticle

Hydrastine Pharmacokinetics and Metabolism after a Single Oral Dose of Goldenseal (Hydrastis canadensis) to Humans

Prem K. Gupta, Gary Barone, Bill J. Gurley, E. Kim Fifer and Howard P. Hendrickson
Drug Metabolism and Disposition April 2015, 43 (4) 534-552; DOI: https://doi.org/10.1124/dmd.114.059410
Prem K. Gupta
Department of Pharmaceutical Sciences, College of Pharmacy (P.K.G., B.J.G., E.K.F., H.P.H.), and Department of Surgery, College of Medicine (G.B.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Gary Barone
Department of Pharmaceutical Sciences, College of Pharmacy (P.K.G., B.J.G., E.K.F., H.P.H.), and Department of Surgery, College of Medicine (G.B.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Bill J. Gurley
Department of Pharmaceutical Sciences, College of Pharmacy (P.K.G., B.J.G., E.K.F., H.P.H.), and Department of Surgery, College of Medicine (G.B.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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E. Kim Fifer
Department of Pharmaceutical Sciences, College of Pharmacy (P.K.G., B.J.G., E.K.F., H.P.H.), and Department of Surgery, College of Medicine (G.B.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Howard P. Hendrickson
Department of Pharmaceutical Sciences, College of Pharmacy (P.K.G., B.J.G., E.K.F., H.P.H.), and Department of Surgery, College of Medicine (G.B.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
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Article Information

vol. 43 no. 4 534-552
DOI 
https://doi.org/10.1124/dmd.114.059410
PubMed 
25609220

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received July 9, 2014
  • Accepted January 20, 2015
  • Published online February 23, 2015.

Article Versions

  • Earlier version (January 21, 2015 - 08:06).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2015 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Prem K. Gupta,
  2. Gary Barone,
  3. Bill J. Gurley,
  4. E. Kim Fifer, and
  5. Howard P. Hendrickson
  1. Department of Pharmaceutical Sciences, College of Pharmacy (P.K.G., B.J.G., E.K.F., H.P.H.), and Department of Surgery, College of Medicine (G.B.), University of Arkansas for Medical Sciences, Little Rock, Arkansas
  1. Address correspondence to:
    Howard P. Hendrickson, Ph.D., Department of Pharmaceutical Sciences, College of Pharmacy, University of Arkansas for Medical Sciences #622, 4301 West Markham Street, Little Rock, AR 72205. E-mail: hendricksonhowardp{at}uams.edu
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Drug Metabolism and Disposition: 43 (4)
Drug Metabolism and Disposition
Vol. 43, Issue 4
1 Apr 2015
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Research ArticleArticle

Hydrastine ADME in Humans after a Single Dose of Goldenseal

Prem K. Gupta, Gary Barone, Bill J. Gurley, E. Kim Fifer and Howard P. Hendrickson
Drug Metabolism and Disposition April 1, 2015, 43 (4) 534-552; DOI: https://doi.org/10.1124/dmd.114.059410

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Research ArticleArticle

Hydrastine ADME in Humans after a Single Dose of Goldenseal

Prem K. Gupta, Gary Barone, Bill J. Gurley, E. Kim Fifer and Howard P. Hendrickson
Drug Metabolism and Disposition April 1, 2015, 43 (4) 534-552; DOI: https://doi.org/10.1124/dmd.114.059410
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