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Index by author

May 01, 2015; Volume 43,Issue 5

A

  1. A, Jiye

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  2. Amano, Hirotaka

    1. Metabolism, Excretion, and Pharmacokinetics of S-Allyl-l-Cysteine in Rats and Dogs
      Hirotaka Amano, Daichi Kazamori, Kenji Itoh and Yukihiro Kodera
      Drug Metabolism and Disposition May 2015, 43 (5) 749-755; DOI: https://doi.org/10.1124/dmd.115.063230

  3. Anzai, Kazuya

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  4. Aoki, Yasuhiro

    1. CYP2A7 Pseudogene Transcript Affects CYP2A6 Expression in Human Liver by Acting as a Decoy for miR-126*
      Masataka Nakano, Yasunari Fukushima, Shin-ichi Yokota, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition May 2015, 43 (5) 703-712; DOI: https://doi.org/10.1124/dmd.115.063255

  5. Arase, Yoshitaka

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  6. Ayanoglu, Gulesi

    1. Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters
      Theresa V. Nguyen, Okechukwu Ukairo, Salman R. Khetani, Michael McVay, Chitra Kanchagar, Wolfgang Seghezzi, Gulesi Ayanoglu, Onyi Irrechukwu and Raymond Evers
      Drug Metabolism and Disposition May 2015, 43 (5) 774-785; DOI: https://doi.org/10.1124/dmd.114.061317

B

  1. Bedwell, David W.

    1. In Vitro Characterization of the Bioconversion of Pomaglumetad Methionil, a Novel Metabotropic Glutamate 2/3 Receptor Agonist Peptide Prodrug
      Richard D. Moulton, Kenneth J. Ruterbories, David W. Bedwell and Michael A. Mohutsky
      Drug Metabolism and Disposition May 2015, 43 (5) 756-761; DOI: https://doi.org/10.1124/dmd.114.062893

  2. Brouwer, Kim L. R.

    1. Toward Predicting Drug-Induced Liver Injury: Parallel Computational Approaches to Identify Multidrug Resistance Protein 4 and Bile Salt Export Pump Inhibitors
      Matthew A. Welch, Kathleen Köck, Thomas J. Urban, Kim L. R. Brouwer and Peter W. Swaan
      Drug Metabolism and Disposition May 2015, 43 (5) 725-734; DOI: https://doi.org/10.1124/dmd.114.062539

  3. Bumpus, Namandjé N.

    1. Response to “Clinical Relevance of CYP3A5 Genotype on Maraviroc Exposures”
      Yanhui Lu, Edward J. Fuchs, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition May 2015, 43 (5) 773; DOI: https://doi.org/10.1124/dmd.115.064188

C

  1. Chen, Xiaoyan

    1. Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes
      Jian Meng, Dafang Zhong, Liang Li, Zhengyu Yuan, Hong Yuan, Cen Xie, Jialan Zhou, Chen Li, Mikhail Fedorovich Gordeev, Jinqian Liu and Xiaoyan Chen
      Drug Metabolism and Disposition May 2015, 43 (5) 646-659; DOI: https://doi.org/10.1124/dmd.114.061747

  2. Clark, Andrew

    1. Clinical Relevance of CYP3A5 Genotype on Maraviroc Exposures
      Manoli Vourvahis, Lynn McFadyen, Jayvant Heera and Andrew Clark
      Drug Metabolism and Disposition May 2015, 43 (5) 771-772; DOI: https://doi.org/10.1124/dmd.115.063321

D

  1. Davis, Hugh M.

    1. Pharmacokinetics and Immunogenicity Investigation of a Human Anti-Interleukin-17 Monoclonal Antibody in Non-Naïve Cynomolgus Monkeys
      Chao Han, George R. Gunn, Joseph C. Marini, Gopi Shankar, Helen Han Hsu and Hugh M. Davis
      Drug Metabolism and Disposition May 2015, 43 (5) 762-770; DOI: https://doi.org/10.1124/dmd.114.062679

  2. Ding, Xinxin

    1. Suppression of Pulmonary CYP2A13 Expression by Carcinogen-Induced Lung Tumorigenesis in a CYP2A13-Humanized Mouse Model
      Zhihua Liu, Vandana Megaraj, Lei Li, Stewart Sell, Jing Hu and Xinxin Ding
      Drug Metabolism and Disposition May 2015, 43 (5) 698-702; DOI: https://doi.org/10.1124/dmd.115.063305

  3. Dong, Jiajia

    1. Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions
      Weiwei Jia, Feifei Du, Xinwei Liu, Rongrong Jiang, Fang Xu, Junling Yang, Li Li, Fengqing Wang, Olajide E. Olaleye, Jiajia Dong and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 669-678; DOI: https://doi.org/10.1124/dmd.114.062000
    2. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  4. Du, Feifei

    1. Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions
      Weiwei Jia, Feifei Du, Xinwei Liu, Rongrong Jiang, Fang Xu, Junling Yang, Li Li, Fengqing Wang, Olajide E. Olaleye, Jiajia Dong and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 669-678; DOI: https://doi.org/10.1124/dmd.114.062000
    2. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

E

  1. Ebinuma, Hirotoshi

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  2. Evers, Raymond

    1. Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters
      Theresa V. Nguyen, Okechukwu Ukairo, Salman R. Khetani, Michael McVay, Chitra Kanchagar, Wolfgang Seghezzi, Gulesi Ayanoglu, Onyi Irrechukwu and Raymond Evers
      Drug Metabolism and Disposition May 2015, 43 (5) 774-785; DOI: https://doi.org/10.1124/dmd.114.061317

F

  1. Fuchs, Edward J.

    1. Response to “Clinical Relevance of CYP3A5 Genotype on Maraviroc Exposures”
      Yanhui Lu, Edward J. Fuchs, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition May 2015, 43 (5) 773; DOI: https://doi.org/10.1124/dmd.115.064188

  2. Fukami, Tatsuki

    1. CYP2A7 Pseudogene Transcript Affects CYP2A6 Expression in Human Liver by Acting as a Decoy for miR-126*
      Masataka Nakano, Yasunari Fukushima, Shin-ichi Yokota, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition May 2015, 43 (5) 703-712; DOI: https://doi.org/10.1124/dmd.115.063255

  3. Fukushima, Yasunari

    1. CYP2A7 Pseudogene Transcript Affects CYP2A6 Expression in Human Liver by Acting as a Decoy for miR-126*
      Masataka Nakano, Yasunari Fukushima, Shin-ichi Yokota, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition May 2015, 43 (5) 703-712; DOI: https://doi.org/10.1124/dmd.115.063255

G

  1. Gordeev, Mikhail Fedorovich

    1. Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes
      Jian Meng, Dafang Zhong, Liang Li, Zhengyu Yuan, Hong Yuan, Cen Xie, Jialan Zhou, Chen Li, Mikhail Fedorovich Gordeev, Jinqian Liu and Xiaoyan Chen
      Drug Metabolism and Disposition May 2015, 43 (5) 646-659; DOI: https://doi.org/10.1124/dmd.114.061747

  2. Gunn, George R.

    1. Pharmacokinetics and Immunogenicity Investigation of a Human Anti-Interleukin-17 Monoclonal Antibody in Non-Naïve Cynomolgus Monkeys
      Chao Han, George R. Gunn, Joseph C. Marini, Gopi Shankar, Helen Han Hsu and Hugh M. Davis
      Drug Metabolism and Disposition May 2015, 43 (5) 762-770; DOI: https://doi.org/10.1124/dmd.114.062679

H

  1. Hammock, Bruce D.

    1. The 2014 Bernard B. Brodie Award Lecture—Epoxide Hydrolases: Drug Metabolism to Therapeutics for Chronic Pain
      Sean D. Kodani and Bruce D. Hammock
      Drug Metabolism and Disposition May 2015, 43 (5) 788-802; DOI: https://doi.org/10.1124/dmd.115.063339

  2. Han, Chao

    1. Pharmacokinetics and Immunogenicity Investigation of a Human Anti-Interleukin-17 Monoclonal Antibody in Non-Naïve Cynomolgus Monkeys
      Chao Han, George R. Gunn, Joseph C. Marini, Gopi Shankar, Helen Han Hsu and Hugh M. Davis
      Drug Metabolism and Disposition May 2015, 43 (5) 762-770; DOI: https://doi.org/10.1124/dmd.114.062679

  3. Han Hsu, Helen

    1. Pharmacokinetics and Immunogenicity Investigation of a Human Anti-Interleukin-17 Monoclonal Antibody in Non-Naïve Cynomolgus Monkeys
      Chao Han, George R. Gunn, Joseph C. Marini, Gopi Shankar, Helen Han Hsu and Hugh M. Davis
      Drug Metabolism and Disposition May 2015, 43 (5) 762-770; DOI: https://doi.org/10.1124/dmd.114.062679

  4. Heera, Jayvant

    1. Clinical Relevance of CYP3A5 Genotype on Maraviroc Exposures
      Manoli Vourvahis, Lynn McFadyen, Jayvant Heera and Andrew Clark
      Drug Metabolism and Disposition May 2015, 43 (5) 771-772; DOI: https://doi.org/10.1124/dmd.115.063321

  5. Hendrix, Craig W.

    1. Response to “Clinical Relevance of CYP3A5 Genotype on Maraviroc Exposures”
      Yanhui Lu, Edward J. Fuchs, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition May 2015, 43 (5) 773; DOI: https://doi.org/10.1124/dmd.115.064188

  6. Hirose, Shunji

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  7. Ho, Rodney J. Y.

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  8. Hokari, Ryota

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  9. Horie, Yoshinori

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  10. Hu, Dong Gui

    1. Induction of Human UDP-Glucuronosyltransferase 2B7 Gene Expression by Cytotoxic Anticancer Drugs in Liver Cancer HepG2 Cells
      Dong Gui Hu, Peter I. Mackenzie, Lu Lu, Robyn Meech and Ross A. McKinnon
      Drug Metabolism and Disposition May 2015, 43 (5) 660-668; DOI: https://doi.org/10.1124/dmd.114.062380

  11. Hu, Jing

    1. Suppression of Pulmonary CYP2A13 Expression by Carcinogen-Induced Lung Tumorigenesis in a CYP2A13-Humanized Mouse Model
      Zhihua Liu, Vandana Megaraj, Lei Li, Stewart Sell, Jing Hu and Xinxin Ding
      Drug Metabolism and Disposition May 2015, 43 (5) 698-702; DOI: https://doi.org/10.1124/dmd.115.063305

  12. Huang, Yühong

    1. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

I

  1. Ieda, Satsuki

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  2. Inoko, Hidetoshi

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  3. Inoue, Takashi

    1. Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (<em>Callithrix jacchus</em>)
      Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (Callithrix jacchus)
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Norie Murayama, Makiko Shimizu, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2015, 43 (5) 735-742; DOI: https://doi.org/10.1124/dmd.115.063594

  4. Irrechukwu, Onyi

    1. Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters
      Theresa V. Nguyen, Okechukwu Ukairo, Salman R. Khetani, Michael McVay, Chitra Kanchagar, Wolfgang Seghezzi, Gulesi Ayanoglu, Onyi Irrechukwu and Raymond Evers
      Drug Metabolism and Disposition May 2015, 43 (5) 774-785; DOI: https://doi.org/10.1124/dmd.114.061317

  5. Itoh, Kenji

    1. Metabolism, Excretion, and Pharmacokinetics of S-Allyl-l-Cysteine in Rats and Dogs
      Hirotaka Amano, Daichi Kazamori, Kenji Itoh and Yukihiro Kodera
      Drug Metabolism and Disposition May 2015, 43 (5) 749-755; DOI: https://doi.org/10.1124/dmd.115.063230

J

  1. Jeong, Hyunyoung

    1. GW4064, an Agonist of Farnesoid X Receptor, Represses CYP3A4 Expression in Human Hepatocytes by Inducing Small Heterodimer Partner Expression
      Shu Zhang, Xian Pan and Hyunyoung Jeong
      Drug Metabolism and Disposition May 2015, 43 (5) 743-748; DOI: https://doi.org/10.1124/dmd.114.062836

  2. Jia, Lifu

    1. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  3. Jia, Weiwei

    1. Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions
      Weiwei Jia, Feifei Du, Xinwei Liu, Rongrong Jiang, Fang Xu, Junling Yang, Li Li, Fengqing Wang, Olajide E. Olaleye, Jiajia Dong and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 669-678; DOI: https://doi.org/10.1124/dmd.114.062000
    2. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  4. Jiang, Rongrong

    1. Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions
      Weiwei Jia, Feifei Du, Xinwei Liu, Rongrong Jiang, Fang Xu, Junling Yang, Li Li, Fengqing Wang, Olajide E. Olaleye, Jiajia Dong and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 669-678; DOI: https://doi.org/10.1124/dmd.114.062000

K

  1. Kagawa, Tatehiro

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  2. Kanchagar, Chitra

    1. Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters
      Theresa V. Nguyen, Okechukwu Ukairo, Salman R. Khetani, Michael McVay, Chitra Kanchagar, Wolfgang Seghezzi, Gulesi Ayanoglu, Onyi Irrechukwu and Raymond Evers
      Drug Metabolism and Disposition May 2015, 43 (5) 774-785; DOI: https://doi.org/10.1124/dmd.114.061317

  3. Kazamori, Daichi

    1. Metabolism, Excretion, and Pharmacokinetics of S-Allyl-l-Cysteine in Rats and Dogs
      Hirotaka Amano, Daichi Kazamori, Kenji Itoh and Yukihiro Kodera
      Drug Metabolism and Disposition May 2015, 43 (5) 749-755; DOI: https://doi.org/10.1124/dmd.115.063230

  4. Khetani, Salman R.

    1. Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters
      Theresa V. Nguyen, Okechukwu Ukairo, Salman R. Khetani, Michael McVay, Chitra Kanchagar, Wolfgang Seghezzi, Gulesi Ayanoglu, Onyi Irrechukwu and Raymond Evers
      Drug Metabolism and Disposition May 2015, 43 (5) 774-785; DOI: https://doi.org/10.1124/dmd.114.061317

  5. Kitamura, Tsuneo

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  6. Köck, Kathleen

    1. Toward Predicting Drug-Induced Liver Injury: Parallel Computational Approaches to Identify Multidrug Resistance Protein 4 and Bile Salt Export Pump Inhibitors
      Matthew A. Welch, Kathleen Köck, Thomas J. Urban, Kim L. R. Brouwer and Peter W. Swaan
      Drug Metabolism and Disposition May 2015, 43 (5) 725-734; DOI: https://doi.org/10.1124/dmd.114.062539

  7. Kodani, Sean D.

    1. The 2014 Bernard B. Brodie Award Lecture—Epoxide Hydrolases: Drug Metabolism to Therapeutics for Chronic Pain
      Sean D. Kodani and Bruce D. Hammock
      Drug Metabolism and Disposition May 2015, 43 (5) 788-802; DOI: https://doi.org/10.1124/dmd.115.063339

  8. Kodera, Yukihiro

    1. Metabolism, Excretion, and Pharmacokinetics of S-Allyl-l-Cysteine in Rats and Dogs
      Hirotaka Amano, Daichi Kazamori, Kenji Itoh and Yukihiro Kodera
      Drug Metabolism and Disposition May 2015, 43 (5) 749-755; DOI: https://doi.org/10.1124/dmd.115.063230

L

  1. Li, Chen

    1. Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes
      Jian Meng, Dafang Zhong, Liang Li, Zhengyu Yuan, Hong Yuan, Cen Xie, Jialan Zhou, Chen Li, Mikhail Fedorovich Gordeev, Jinqian Liu and Xiaoyan Chen
      Drug Metabolism and Disposition May 2015, 43 (5) 646-659; DOI: https://doi.org/10.1124/dmd.114.061747

  2. Li, Chuan

    1. Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions
      Weiwei Jia, Feifei Du, Xinwei Liu, Rongrong Jiang, Fang Xu, Junling Yang, Li Li, Fengqing Wang, Olajide E. Olaleye, Jiajia Dong and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 669-678; DOI: https://doi.org/10.1124/dmd.114.062000
    2. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  3. Li, Jian

    1. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  4. Li, Lei

    1. Suppression of Pulmonary CYP2A13 Expression by Carcinogen-Induced Lung Tumorigenesis in a CYP2A13-Humanized Mouse Model
      Zhihua Liu, Vandana Megaraj, Lei Li, Stewart Sell, Jing Hu and Xinxin Ding
      Drug Metabolism and Disposition May 2015, 43 (5) 698-702; DOI: https://doi.org/10.1124/dmd.115.063305

  5. Li, Li

    1. Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions
      Weiwei Jia, Feifei Du, Xinwei Liu, Rongrong Jiang, Fang Xu, Junling Yang, Li Li, Fengqing Wang, Olajide E. Olaleye, Jiajia Dong and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 669-678; DOI: https://doi.org/10.1124/dmd.114.062000
    2. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  6. Li, Liang

    1. Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes
      Jian Meng, Dafang Zhong, Liang Li, Zhengyu Yuan, Hong Yuan, Cen Xie, Jialan Zhou, Chen Li, Mikhail Fedorovich Gordeev, Jinqian Liu and Xiaoyan Chen
      Drug Metabolism and Disposition May 2015, 43 (5) 646-659; DOI: https://doi.org/10.1124/dmd.114.061747

  7. Li, Meijuan

    1. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  8. Li, Yanfen

    1. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  9. Lim, Justin B. R.

    1. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  10. Liu, Jinghan

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  11. Liu, Jinqian

    1. Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes
      Jian Meng, Dafang Zhong, Liang Li, Zhengyu Yuan, Hong Yuan, Cen Xie, Jialan Zhou, Chen Li, Mikhail Fedorovich Gordeev, Jinqian Liu and Xiaoyan Chen
      Drug Metabolism and Disposition May 2015, 43 (5) 646-659; DOI: https://doi.org/10.1124/dmd.114.061747

  12. Liu, Ke

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  13. Liu, Xinwei

    1. Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions
      Weiwei Jia, Feifei Du, Xinwei Liu, Rongrong Jiang, Fang Xu, Junling Yang, Li Li, Fengqing Wang, Olajide E. Olaleye, Jiajia Dong and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 669-678; DOI: https://doi.org/10.1124/dmd.114.062000

  14. Liu, Zhihua

    1. Suppression of Pulmonary CYP2A13 Expression by Carcinogen-Induced Lung Tumorigenesis in a CYP2A13-Humanized Mouse Model
      Zhihua Liu, Vandana Megaraj, Lei Li, Stewart Sell, Jing Hu and Xinxin Ding
      Drug Metabolism and Disposition May 2015, 43 (5) 698-702; DOI: https://doi.org/10.1124/dmd.115.063305

  15. Lu, Lu

    1. Induction of Human UDP-Glucuronosyltransferase 2B7 Gene Expression by Cytotoxic Anticancer Drugs in Liver Cancer HepG2 Cells
      Dong Gui Hu, Peter I. Mackenzie, Lu Lu, Robyn Meech and Ross A. McKinnon
      Drug Metabolism and Disposition May 2015, 43 (5) 660-668; DOI: https://doi.org/10.1124/dmd.114.062380

  16. Lu, Yanhui

    1. Response to “Clinical Relevance of CYP3A5 Genotype on Maraviroc Exposures”
      Yanhui Lu, Edward J. Fuchs, Craig W. Hendrix and Namandjé N. Bumpus
      Drug Metabolism and Disposition May 2015, 43 (5) 773; DOI: https://doi.org/10.1124/dmd.115.064188

M

  1. Mackenzie, Peter I.

    1. Induction of Human UDP-Glucuronosyltransferase 2B7 Gene Expression by Cytotoxic Anticancer Drugs in Liver Cancer HepG2 Cells
      Dong Gui Hu, Peter I. Mackenzie, Lu Lu, Robyn Meech and Ross A. McKinnon
      Drug Metabolism and Disposition May 2015, 43 (5) 660-668; DOI: https://doi.org/10.1124/dmd.114.062380

  2. Maekawa, Keiko

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  3. Marini, Joseph C.

    1. Pharmacokinetics and Immunogenicity Investigation of a Human Anti-Interleukin-17 Monoclonal Antibody in Non-Naïve Cynomolgus Monkeys
      Chao Han, George R. Gunn, Joseph C. Marini, Gopi Shankar, Helen Han Hsu and Hugh M. Davis
      Drug Metabolism and Disposition May 2015, 43 (5) 762-770; DOI: https://doi.org/10.1124/dmd.114.062679

  4. McFadyen, Lynn

    1. Clinical Relevance of CYP3A5 Genotype on Maraviroc Exposures
      Manoli Vourvahis, Lynn McFadyen, Jayvant Heera and Andrew Clark
      Drug Metabolism and Disposition May 2015, 43 (5) 771-772; DOI: https://doi.org/10.1124/dmd.115.063321

  5. McKinnon, Ross A.

    1. Induction of Human UDP-Glucuronosyltransferase 2B7 Gene Expression by Cytotoxic Anticancer Drugs in Liver Cancer HepG2 Cells
      Dong Gui Hu, Peter I. Mackenzie, Lu Lu, Robyn Meech and Ross A. McKinnon
      Drug Metabolism and Disposition May 2015, 43 (5) 660-668; DOI: https://doi.org/10.1124/dmd.114.062380

  6. McVay, Michael

    1. Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters
      Theresa V. Nguyen, Okechukwu Ukairo, Salman R. Khetani, Michael McVay, Chitra Kanchagar, Wolfgang Seghezzi, Gulesi Ayanoglu, Onyi Irrechukwu and Raymond Evers
      Drug Metabolism and Disposition May 2015, 43 (5) 774-785; DOI: https://doi.org/10.1124/dmd.114.061317

  7. Meech, Robyn

    1. Induction of Human UDP-Glucuronosyltransferase 2B7 Gene Expression by Cytotoxic Anticancer Drugs in Liver Cancer HepG2 Cells
      Dong Gui Hu, Peter I. Mackenzie, Lu Lu, Robyn Meech and Ross A. McKinnon
      Drug Metabolism and Disposition May 2015, 43 (5) 660-668; DOI: https://doi.org/10.1124/dmd.114.062380

  8. Megaraj, Vandana

    1. Suppression of Pulmonary CYP2A13 Expression by Carcinogen-Induced Lung Tumorigenesis in a CYP2A13-Humanized Mouse Model
      Zhihua Liu, Vandana Megaraj, Lei Li, Stewart Sell, Jing Hu and Xinxin Ding
      Drug Metabolism and Disposition May 2015, 43 (5) 698-702; DOI: https://doi.org/10.1124/dmd.115.063305

  9. Meng, Jian

    1. Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes
      Jian Meng, Dafang Zhong, Liang Li, Zhengyu Yuan, Hong Yuan, Cen Xie, Jialan Zhou, Chen Li, Mikhail Fedorovich Gordeev, Jinqian Liu and Xiaoyan Chen
      Drug Metabolism and Disposition May 2015, 43 (5) 646-659; DOI: https://doi.org/10.1124/dmd.114.061747

  10. Mine, Tetsuya

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  11. Miura, Soichiro

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  12. Mohutsky, Michael A.

    1. In Vitro Characterization of the Bioconversion of Pomaglumetad Methionil, a Novel Metabotropic Glutamate 2/3 Receptor Agonist Peptide Prodrug
      Richard D. Moulton, Kenneth J. Ruterbories, David W. Bedwell and Michael A. Mohutsky
      Drug Metabolism and Disposition May 2015, 43 (5) 756-761; DOI: https://doi.org/10.1124/dmd.114.062893

  13. Moulton, Richard D.

    1. In Vitro Characterization of the Bioconversion of Pomaglumetad Methionil, a Novel Metabotropic Glutamate 2/3 Receptor Agonist Peptide Prodrug
      Richard D. Moulton, Kenneth J. Ruterbories, David W. Bedwell and Michael A. Mohutsky
      Drug Metabolism and Disposition May 2015, 43 (5) 756-761; DOI: https://doi.org/10.1124/dmd.114.062893

  14. Murayama, Norie

    1. Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (<em>Callithrix jacchus</em>)
      Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (Callithrix jacchus)
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Norie Murayama, Makiko Shimizu, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2015, 43 (5) 735-742; DOI: https://doi.org/10.1124/dmd.115.063594

N

  1. Nakajima, Miki

    1. CYP2A7 Pseudogene Transcript Affects CYP2A6 Expression in Human Liver by Acting as a Decoy for miR-126*
      Masataka Nakano, Yasunari Fukushima, Shin-ichi Yokota, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition May 2015, 43 (5) 703-712; DOI: https://doi.org/10.1124/dmd.115.063255

  2. Nakano, Masataka

    1. CYP2A7 Pseudogene Transcript Affects CYP2A6 Expression in Human Liver by Acting as a Decoy for miR-126*
      Masataka Nakano, Yasunari Fukushima, Shin-ichi Yokota, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition May 2015, 43 (5) 703-712; DOI: https://doi.org/10.1124/dmd.115.063255

  3. Nakazawa, Takahide

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  4. Nguyen, Theresa V.

    1. Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters
      Theresa V. Nguyen, Okechukwu Ukairo, Salman R. Khetani, Michael McVay, Chitra Kanchagar, Wolfgang Seghezzi, Gulesi Ayanoglu, Onyi Irrechukwu and Raymond Evers
      Drug Metabolism and Disposition May 2015, 43 (5) 774-785; DOI: https://doi.org/10.1124/dmd.114.061317

O

  1. Oka, Akira

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  2. Okuse, Chiaki

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  3. Olaleye, Olajide E.

    1. Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions
      Weiwei Jia, Feifei Du, Xinwei Liu, Rongrong Jiang, Fang Xu, Junling Yang, Li Li, Fengqing Wang, Olajide E. Olaleye, Jiajia Dong and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 669-678; DOI: https://doi.org/10.1124/dmd.114.062000
    2. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  4. Orii, Reiko

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

P

  1. Pan, Xian

    1. GW4064, an Agonist of Farnesoid X Receptor, Represses CYP3A4 Expression in Human Hepatocytes by Inducing Small Heterodimer Partner Expression
      Shu Zhang, Xian Pan and Hyunyoung Jeong
      Drug Metabolism and Disposition May 2015, 43 (5) 743-748; DOI: https://doi.org/10.1124/dmd.114.062836

  2. Peng, Ying

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

Q

  1. Qi, Huanhuan

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

R

  1. Ruterbories, Kenneth J.

    1. In Vitro Characterization of the Bioconversion of Pomaglumetad Methionil, a Novel Metabotropic Glutamate 2/3 Receptor Agonist Peptide Prodrug
      Richard D. Moulton, Kenneth J. Ruterbories, David W. Bedwell and Michael A. Mohutsky
      Drug Metabolism and Disposition May 2015, 43 (5) 756-761; DOI: https://doi.org/10.1124/dmd.114.062893

S

  1. Saito, Hidetsugu

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  2. Saito, Yoshiro

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  3. Sasaki, Erika

    1. Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (<em>Callithrix jacchus</em>)
      Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (Callithrix jacchus)
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Norie Murayama, Makiko Shimizu, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2015, 43 (5) 735-742; DOI: https://doi.org/10.1124/dmd.115.063594

  4. Seghezzi, Wolfgang

    1. Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters
      Theresa V. Nguyen, Okechukwu Ukairo, Salman R. Khetani, Michael McVay, Chitra Kanchagar, Wolfgang Seghezzi, Gulesi Ayanoglu, Onyi Irrechukwu and Raymond Evers
      Drug Metabolism and Disposition May 2015, 43 (5) 774-785; DOI: https://doi.org/10.1124/dmd.114.061317

  5. Sell, Stewart

    1. Suppression of Pulmonary CYP2A13 Expression by Carcinogen-Induced Lung Tumorigenesis in a CYP2A13-Humanized Mouse Model
      Zhihua Liu, Vandana Megaraj, Lei Li, Stewart Sell, Jing Hu and Xinxin Ding
      Drug Metabolism and Disposition May 2015, 43 (5) 698-702; DOI: https://doi.org/10.1124/dmd.115.063305

  6. Shang, Lili

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  7. Shankar, Gopi

    1. Pharmacokinetics and Immunogenicity Investigation of a Human Anti-Interleukin-17 Monoclonal Antibody in Non-Naïve Cynomolgus Monkeys
      Chao Han, George R. Gunn, Joseph C. Marini, Gopi Shankar, Helen Han Hsu and Hugh M. Davis
      Drug Metabolism and Disposition May 2015, 43 (5) 762-770; DOI: https://doi.org/10.1124/dmd.114.062679

  8. Shimizu, Makiko

    1. Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (<em>Callithrix jacchus</em>)
      Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (Callithrix jacchus)
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Norie Murayama, Makiko Shimizu, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2015, 43 (5) 735-742; DOI: https://doi.org/10.1124/dmd.115.063594

  9. Shiraishi, Koichi

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  10. Sun, Jianguo

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  11. Sun, Yue

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  12. Swaan, Peter W.

    1. Toward Predicting Drug-Induced Liver Injury: Parallel Computational Approaches to Identify Multidrug Resistance Protein 4 and Bile Salt Export Pump Inhibitors
      Matthew A. Welch, Kathleen Köck, Thomas J. Urban, Kim L. R. Brouwer and Peter W. Swaan
      Drug Metabolism and Disposition May 2015, 43 (5) 725-734; DOI: https://doi.org/10.1124/dmd.114.062539

T

  1. Takamiya, Masataka

    1. CYP2A7 Pseudogene Transcript Affects CYP2A6 Expression in Human Liver by Acting as a Decoy for miR-126*
      Masataka Nakano, Yasunari Fukushima, Shin-ichi Yokota, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition May 2015, 43 (5) 703-712; DOI: https://doi.org/10.1124/dmd.115.063255

  2. Takikawa, Hajime

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  3. Tohkin, Masahiro

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  4. Tomita, Kengo

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  5. Tsuruya, Kota

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

U

  1. Uehara, Shotaro

    1. Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (<em>Callithrix jacchus</em>)
      Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (Callithrix jacchus)
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Norie Murayama, Makiko Shimizu, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2015, 43 (5) 735-742; DOI: https://doi.org/10.1124/dmd.115.063594

  2. Ukairo, Okechukwu

    1. Establishment of a Hepatocyte-Kupffer Cell Coculture Model for Assessment of Proinflammatory Cytokine Effects on Metabolizing Enzymes and Drug Transporters
      Theresa V. Nguyen, Okechukwu Ukairo, Salman R. Khetani, Michael McVay, Chitra Kanchagar, Wolfgang Seghezzi, Gulesi Ayanoglu, Onyi Irrechukwu and Raymond Evers
      Drug Metabolism and Disposition May 2015, 43 (5) 774-785; DOI: https://doi.org/10.1124/dmd.114.061317

  3. Uno, Yasuhiro

    1. Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (<em>Callithrix jacchus</em>)
      Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (Callithrix jacchus)
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Norie Murayama, Makiko Shimizu, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2015, 43 (5) 735-742; DOI: https://doi.org/10.1124/dmd.115.063594

  4. Urban, Thomas J.

    1. Toward Predicting Drug-Induced Liver Injury: Parallel Computational Approaches to Identify Multidrug Resistance Protein 4 and Bile Salt Export Pump Inhibitors
      Matthew A. Welch, Kathleen Köck, Thomas J. Urban, Kim L. R. Brouwer and Peter W. Swaan
      Drug Metabolism and Disposition May 2015, 43 (5) 725-734; DOI: https://doi.org/10.1124/dmd.114.062539

V

  1. Vourvahis, Manoli

    1. Clinical Relevance of CYP3A5 Genotype on Maraviroc Exposures
      Manoli Vourvahis, Lynn McFadyen, Jayvant Heera and Andrew Clark
      Drug Metabolism and Disposition May 2015, 43 (5) 771-772; DOI: https://doi.org/10.1124/dmd.115.063321

W

  1. Wang, Fengqing

    1. Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions
      Weiwei Jia, Feifei Du, Xinwei Liu, Rongrong Jiang, Fang Xu, Junling Yang, Li Li, Fengqing Wang, Olajide E. Olaleye, Jiajia Dong and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 669-678; DOI: https://doi.org/10.1124/dmd.114.062000
    2. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  2. Wang, Guangji

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  3. Wasada, Mitsuru

    1. No Contribution of the ABCB11 p.444A Polymorphism in Japanese Patients with Drug-Induced Cholestasis
      Tatehiro Kagawa, Shunji Hirose, Yoshitaka Arase, Akira Oka, Kazuya Anzai, Kota Tsuruya, Koichi Shiraishi, Reiko Orii, Satsuki Ieda, Takahide Nakazawa, Kengo Tomita, Ryota Hokari, Soichiro Miura, Hirotoshi Ebinuma, Hidetsugu Saito, Tsuneo Kitamura, Yoshinori Horie, Chiaki Okuse, Mitsuru Wasada, Hidetoshi Inoko, Masahiro Tohkin, Yoshiro Saito, Keiko Maekawa, Hajime Takikawa and Tetsuya Mine
      Drug Metabolism and Disposition May 2015, 43 (5) 691-697; DOI: https://doi.org/10.1124/dmd.114.061325

  4. Welch, Matthew A.

    1. Toward Predicting Drug-Induced Liver Injury: Parallel Computational Approaches to Identify Multidrug Resistance Protein 4 and Bile Salt Export Pump Inhibitors
      Matthew A. Welch, Kathleen Köck, Thomas J. Urban, Kim L. R. Brouwer and Peter W. Swaan
      Drug Metabolism and Disposition May 2015, 43 (5) 725-734; DOI: https://doi.org/10.1124/dmd.114.062539

  5. Wu, Hui

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

X

  1. Xiao, Yanan

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  2. Xie, Cen

    1. Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes
      Jian Meng, Dafang Zhong, Liang Li, Zhengyu Yuan, Hong Yuan, Cen Xie, Jialan Zhou, Chen Li, Mikhail Fedorovich Gordeev, Jinqian Liu and Xiaoyan Chen
      Drug Metabolism and Disposition May 2015, 43 (5) 646-659; DOI: https://doi.org/10.1124/dmd.114.061747

  3. Xu, Fang

    1. Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions
      Weiwei Jia, Feifei Du, Xinwei Liu, Rongrong Jiang, Fang Xu, Junling Yang, Li Li, Fengqing Wang, Olajide E. Olaleye, Jiajia Dong and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 669-678; DOI: https://doi.org/10.1124/dmd.114.062000
    2. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

Y

  1. Yamazaki, Hiroshi

    1. Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (<em>Callithrix jacchus</em>)
      Activation and Deactivation of 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine by Cytochrome P450 Enzymes and Flavin-Containing Monooxygenases in Common Marmosets (Callithrix jacchus)
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Norie Murayama, Makiko Shimizu, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition May 2015, 43 (5) 735-742; DOI: https://doi.org/10.1124/dmd.115.063594

  2. Yang, Junling

    1. Renal Tubular Secretion of Tanshinol: Molecular Mechanisms, Impact on Its Systemic Exposure, and Propensity for Dose-Related Nephrotoxicity and for Renal Herb-Drug Interactions
      Weiwei Jia, Feifei Du, Xinwei Liu, Rongrong Jiang, Fang Xu, Junling Yang, Li Li, Fengqing Wang, Olajide E. Olaleye, Jiajia Dong and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 669-678; DOI: https://doi.org/10.1124/dmd.114.062000

  3. Yokoi, Tsuyoshi

    1. CYP2A7 Pseudogene Transcript Affects CYP2A6 Expression in Human Liver by Acting as a Decoy for miR-126*
      Masataka Nakano, Yasunari Fukushima, Shin-ichi Yokota, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition May 2015, 43 (5) 703-712; DOI: https://doi.org/10.1124/dmd.115.063255

  4. Yokota, Shin-ichi

    1. CYP2A7 Pseudogene Transcript Affects CYP2A6 Expression in Human Liver by Acting as a Decoy for miR-126*
      Masataka Nakano, Yasunari Fukushima, Shin-ichi Yokota, Tatsuki Fukami, Masataka Takamiya, Yasuhiro Aoki, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition May 2015, 43 (5) 703-712; DOI: https://doi.org/10.1124/dmd.115.063255

  5. Yuan, Hong

    1. Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes
      Jian Meng, Dafang Zhong, Liang Li, Zhengyu Yuan, Hong Yuan, Cen Xie, Jialan Zhou, Chen Li, Mikhail Fedorovich Gordeev, Jinqian Liu and Xiaoyan Chen
      Drug Metabolism and Disposition May 2015, 43 (5) 646-659; DOI: https://doi.org/10.1124/dmd.114.061747

  6. Yuan, Zhengyu

    1. Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes
      Jian Meng, Dafang Zhong, Liang Li, Zhengyu Yuan, Hong Yuan, Cen Xie, Jialan Zhou, Chen Li, Mikhail Fedorovich Gordeev, Jinqian Liu and Xiaoyan Chen
      Drug Metabolism and Disposition May 2015, 43 (5) 646-659; DOI: https://doi.org/10.1124/dmd.114.061747

Z

  1. Zhang, Fengyi

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  2. Zhang, Shu

    1. GW4064, an Agonist of Farnesoid X Receptor, Represses CYP3A4 Expression in Human Hepatocytes by Inducing Small Heterodimer Partner Expression
      Shu Zhang, Xian Pan and Hyunyoung Jeong
      Drug Metabolism and Disposition May 2015, 43 (5) 743-748; DOI: https://doi.org/10.1124/dmd.114.062836

  3. Zhang, Xueyuan

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  4. Zhao, Buchang

    1. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  5. Zhong, Chenchun

    1. Systemic Exposure to and Disposition of Catechols Derived from Salvia miltiorrhiza Roots (Danshen) after Intravenous Dosing DanHong Injection in Human Subjects, Rats, and Dogs
      Meijuan Li, Fengqing Wang, Yühong Huang, Feifei Du, Chenchun Zhong, Olajide E. Olaleye, Weiwei Jia, Yanfen Li, Fang Xu, Jiajia Dong, Jian Li, Justin B. R. Lim, Buchang Zhao, Lifu Jia, Li Li and Chuan Li
      Drug Metabolism and Disposition May 2015, 43 (5) 679-690; DOI: https://doi.org/10.1124/dmd.114.061473

  6. Zhong, Dafang

    1. Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes
      Jian Meng, Dafang Zhong, Liang Li, Zhengyu Yuan, Hong Yuan, Cen Xie, Jialan Zhou, Chen Li, Mikhail Fedorovich Gordeev, Jinqian Liu and Xiaoyan Chen
      Drug Metabolism and Disposition May 2015, 43 (5) 646-659; DOI: https://doi.org/10.1124/dmd.114.061747

  7. Zhong, Yunxi

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905

  8. Zhou, Jialan

    1. Metabolism of MRX-I, a Novel Antibacterial Oxazolidinone, in Humans: The Oxidative Ring Opening of 2,3-Dihydropyridin-4-One Catalyzed by Non-P450 Enzymes
      Jian Meng, Dafang Zhong, Liang Li, Zhengyu Yuan, Hong Yuan, Cen Xie, Jialan Zhou, Chen Li, Mikhail Fedorovich Gordeev, Jinqian Liu and Xiaoyan Chen
      Drug Metabolism and Disposition May 2015, 43 (5) 646-659; DOI: https://doi.org/10.1124/dmd.114.061747

  9. Zhu, Jianping

    1. Guanfu Base A, an Antiarrhythmic Alkaloid of Aconitum coreanum, Is a CYP2D6 Inhibitor of Human, Monkey, and Dog Isoforms
      Jianguo Sun, Ying Peng, Hui Wu, Xueyuan Zhang, Yunxi Zhong, Yanan Xiao, Fengyi Zhang, Huanhuan Qi, Lili Shang, Jianping Zhu, Yue Sun, Ke Liu, Jinghan Liu, Jiye A, Rodney J. Y. Ho and Guangji Wang
      Drug Metabolism and Disposition May 2015, 43 (5) 713-724; DOI: https://doi.org/10.1124/dmd.114.060905
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