Table of Contents

Articles

• You have access

  Mechanistic Investigation of the Preclinical Pharmacokinetics and Interspecies Scaling of PF-05231023, a Fibroblast Growth Factor 21–Antibody Protein Conjugate

  Craig Giragossian, Chandra Vage, Jun Li, Kathleen Pelletier, Nicole Piché-Nicholas, Manoj Rajadhyaksha, Jennifer Liras, Alison Logan, Roberto A. Calle and Yan Weng

  Drug Metabolism and Disposition June 2015, 43 (6) 803-811; DOI: https://doi.org/10.1124/dmd.114.061713
• You have access

  Targeted Screen for Human UDP-Glucuronosyltransferases Inhibitors and the Evaluation of Potential Drug-Drug Interactions with Zafirlukast

  Shingo Oda, Ryoichi Fujiwara, Yuki Kutsuno, Tatsuki Fukami, Tomoo Itoh, Tsuyoshi Yokoi and Miki Nakajima

  Drug Metabolism and Disposition June 2015, 43 (6) 812-818; DOI: https://doi.org/10.1124/dmd.114.062141
• You have access

  Short-Term Fasting Alters Cytochrome P450–Mediated Drug Metabolism in Humans

  Laureen A. Lammers, Roos Achterbergh, Emmely M. de Vries, F. Samuel van Nierop, Heinz-Josef Klümpen, Maarten R. Soeters, Anita Boelen, Johannes A. Romijn and Ron A. A. Mathôt

  Drug Metabolism and Disposition June 2015, 43 (6) 819-828; DOI: https://doi.org/10.1124/dmd.114.062299
• You have access

  Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis

  Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington

  Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703
• You have access

  Prediction of Gestational Age–Dependent Induction of In Vivo Hepatic CYP3A Activity Based on HepaRG Cells and Human Hepatocytes

  Zufei Zhang, Muhammad Farooq, Bhagwat Prasad, Sue Grepper and Jashvant D. Unadkat

  Drug Metabolism and Disposition June 2015, 43 (6) 836-842; DOI: https://doi.org/10.1124/dmd.114.062984
• You have access

  The Effects of Endoxifen and Other Major Metabolites of Tamoxifen on the Sulfation of Estradiol Catalyzed by Human Cytosolic Sulfotransferases hSULT1E1 and hSULT1A1*1

  Edwin J. Squirewell and Michael W. Duffel

  Drug Metabolism and Disposition June 2015, 43 (6) 843-850; DOI: https://doi.org/10.1124/dmd.115.063206
• You have access

  Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans

  Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers

  Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347
• You have access

  Prediction of In Vivo Clearance and Associated Variability of CYP2C19 Substrates by Genotypes in Populations Utilizing a Pharmacogenetics-Based Mechanistic Model

  Boyd Steere, Jessica A. Roseberry Baker, Stephen D. Hall and Yingying Guo

  Drug Metabolism and Disposition June 2015, 43 (6) 870-883; DOI: https://doi.org/10.1124/dmd.114.061523
• You have access

  Induction of UDP-Glucuronosyltransferase 2B15 Gene Expression by the Major Active Metabolites of Tamoxifen, 4-Hydroxytamoxifen and Endoxifen, in Breast Cancer Cells

  Apichaya Chanawong, Dong Gui Hu, Robyn Meech, Peter I. Mackenzie and Ross A. McKinnon

  Drug Metabolism and Disposition June 2015, 43 (6) 889-897; DOI: https://doi.org/10.1124/dmd.114.062935
• You have access

  Biodistribution of Etanercept to Tissues and Sites of Inflammation in Arthritic Rats

  Xi Chen, Debra C. DuBois, Richard R. Almon and William J. Jusko

  Drug Metabolism and Disposition June 2015, 43 (6) 898-907; DOI: https://doi.org/10.1124/dmd.114.062901
• You have access

  A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834

  Jasleen K. Sodhi, Susan Wong, Donald S. Kirkpatrick, Lichuan Liu, S. Cyrus Khojasteh, Cornelis E. C. A. Hop, John T. Barr, Jeffrey P. Jones and Jason S. Halladay

  Drug Metabolism and Disposition June 2015, 43 (6) 908-915; DOI: https://doi.org/10.1124/dmd.114.061804