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Index by author

June 01, 2015; Volume 43,Issue 6

A

  1. Achterbergh, Roos

    1. Short-Term Fasting Alters Cytochrome P450–Mediated Drug Metabolism in Humans
      Laureen A. Lammers, Roos Achterbergh, Emmely M. de Vries, F. Samuel van Nierop, Heinz-Josef Klümpen, Maarten R. Soeters, Anita Boelen, Johannes A. Romijn and Ron A. A. Mathôt
      Drug Metabolism and Disposition June 2015, 43 (6) 819-828; DOI: https://doi.org/10.1124/dmd.114.062299

  2. Almon, Richard R.

    1. Biodistribution of Etanercept to Tissues and Sites of Inflammation in Arthritic Rats
      Xi Chen, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition June 2015, 43 (6) 898-907; DOI: https://doi.org/10.1124/dmd.114.062901

B

  1. Baker, Jessica A. Roseberry

    1. Prediction of In Vivo Clearance and Associated Variability of CYP2C19 Substrates by Genotypes in Populations Utilizing a Pharmacogenetics-Based Mechanistic Model
      Boyd Steere, Jessica A. Roseberry Baker, Stephen D. Hall and Yingying Guo
      Drug Metabolism and Disposition June 2015, 43 (6) 870-883; DOI: https://doi.org/10.1124/dmd.114.061523

  2. Barr, John T.

    1. A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834
      Jasleen K. Sodhi, Susan Wong, Donald S. Kirkpatrick, Lichuan Liu, S. Cyrus Khojasteh, Cornelis E. C. A. Hop, John T. Barr, Jeffrey P. Jones and Jason S. Halladay
      Drug Metabolism and Disposition June 2015, 43 (6) 908-915; DOI: https://doi.org/10.1124/dmd.114.061804

  3. Bataille, Amy M.

    1. Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis
      Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington
      Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703

  4. Boelen, Anita

    1. Short-Term Fasting Alters Cytochrome P450–Mediated Drug Metabolism in Humans
      Laureen A. Lammers, Roos Achterbergh, Emmely M. de Vries, F. Samuel van Nierop, Heinz-Josef Klümpen, Maarten R. Soeters, Anita Boelen, Johannes A. Romijn and Ron A. A. Mathôt
      Drug Metabolism and Disposition June 2015, 43 (6) 819-828; DOI: https://doi.org/10.1124/dmd.114.062299

C

  1. Cai, Xiaoxin

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  2. Calle, Roberto A.

    1. Mechanistic Investigation of the Preclinical Pharmacokinetics and Interspecies Scaling of PF-05231023, a Fibroblast Growth Factor 21–Antibody Protein Conjugate
      Craig Giragossian, Chandra Vage, Jun Li, Kathleen Pelletier, Nicole Piché-Nicholas, Manoj Rajadhyaksha, Jennifer Liras, Alison Logan, Roberto A. Calle and Yan Weng
      Drug Metabolism and Disposition June 2015, 43 (6) 803-811; DOI: https://doi.org/10.1124/dmd.114.061713

  3. Campion, Sarah N.

    1. Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis
      Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington
      Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703

  4. Canet, Mark J.

    1. Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis
      Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington
      Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703

  5. Castro-Perez, Jose

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  6. Chan, Grace H.

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  7. Chanawong, Apichaya

    1. Induction of UDP-Glucuronosyltransferase 2B15 Gene Expression by the Major Active Metabolites of Tamoxifen, 4-Hydroxytamoxifen and Endoxifen, in Breast Cancer Cells
      Apichaya Chanawong, Dong Gui Hu, Robyn Meech, Peter I. Mackenzie and Ross A. McKinnon
      Drug Metabolism and Disposition June 2015, 43 (6) 889-897; DOI: https://doi.org/10.1124/dmd.114.062935

  8. Chen, Xi

    1. Biodistribution of Etanercept to Tissues and Sites of Inflammation in Arthritic Rats
      Xi Chen, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition June 2015, 43 (6) 898-907; DOI: https://doi.org/10.1124/dmd.114.062901

  9. Cherrington, Nathan J.

    1. Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis
      Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington
      Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703

  10. Choo, Edna F.

    1. Use of Transgenic Mouse Models to Understand the Oral Disposition and Drug-Drug Interaction Potential of Cobimetinib, a MEK Inhibitor
      Edna F. Choo, Sarah Woolsey, Kevin DeMent, Justin Ly, Kirsten Messick, Ann Qin and Ryan Takahashi
      Drug Metabolism and Disposition June 2015, 43 (6) 864-869; DOI: https://doi.org/10.1124/dmd.115.063743

  11. Chu, Xiaoyan

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

D

  1. DeMent, Kevin

    1. Use of Transgenic Mouse Models to Understand the Oral Disposition and Drug-Drug Interaction Potential of Cobimetinib, a MEK Inhibitor
      Edna F. Choo, Sarah Woolsey, Kevin DeMent, Justin Ly, Kirsten Messick, Ann Qin and Ryan Takahashi
      Drug Metabolism and Disposition June 2015, 43 (6) 864-869; DOI: https://doi.org/10.1124/dmd.115.063743

  2. de Vries, Emmely M.

    1. Short-Term Fasting Alters Cytochrome P450–Mediated Drug Metabolism in Humans
      Laureen A. Lammers, Roos Achterbergh, Emmely M. de Vries, F. Samuel van Nierop, Heinz-Josef Klümpen, Maarten R. Soeters, Anita Boelen, Johannes A. Romijn and Ron A. A. Mathôt
      Drug Metabolism and Disposition June 2015, 43 (6) 819-828; DOI: https://doi.org/10.1124/dmd.114.062299

  3. DuBois, Debra C.

    1. Biodistribution of Etanercept to Tissues and Sites of Inflammation in Arthritic Rats
      Xi Chen, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition June 2015, 43 (6) 898-907; DOI: https://doi.org/10.1124/dmd.114.062901

  4. Duffel, Michael W.

    1. The Effects of Endoxifen and Other Major Metabolites of Tamoxifen on the Sulfation of Estradiol Catalyzed by Human Cytosolic Sulfotransferases hSULT1E1 and hSULT1A1*1
      Edwin J. Squirewell and Michael W. Duffel
      Drug Metabolism and Disposition June 2015, 43 (6) 843-850; DOI: https://doi.org/10.1124/dmd.115.063206

E

  1. Erickson, Robert P.

    1. Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis
      Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington
      Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703

  2. Evers, Raymond

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

F

  1. Farooq, Muhammad

    1. Prediction of Gestational Age–Dependent Induction of In Vivo Hepatic CYP3A Activity Based on HepaRG Cells and Human Hepatocytes
      Zufei Zhang, Muhammad Farooq, Bhagwat Prasad, Sue Grepper and Jashvant D. Unadkat
      Drug Metabolism and Disposition June 2015, 43 (6) 836-842; DOI: https://doi.org/10.1124/dmd.114.062984

  2. Fernandis, Aaron

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  3. Ferreira, Daniel W.

    1. Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis
      Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington
      Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703

  4. Fujiwara, Ryoichi

    1. Targeted Screen for Human UDP-Glucuronosyltransferases Inhibitors and the Evaluation of Potential Drug-Drug Interactions with Zafirlukast
      Shingo Oda, Ryoichi Fujiwara, Yuki Kutsuno, Tatsuki Fukami, Tomoo Itoh, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition June 2015, 43 (6) 812-818; DOI: https://doi.org/10.1124/dmd.114.062141

  5. Fukami, Tatsuki

    1. Targeted Screen for Human UDP-Glucuronosyltransferases Inhibitors and the Evaluation of Potential Drug-Drug Interactions with Zafirlukast
      Shingo Oda, Ryoichi Fujiwara, Yuki Kutsuno, Tatsuki Fukami, Tomoo Itoh, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition June 2015, 43 (6) 812-818; DOI: https://doi.org/10.1124/dmd.114.062141

G

  1. Giragossian, Craig

    1. Mechanistic Investigation of the Preclinical Pharmacokinetics and Interspecies Scaling of PF-05231023, a Fibroblast Growth Factor 21–Antibody Protein Conjugate
      Craig Giragossian, Chandra Vage, Jun Li, Kathleen Pelletier, Nicole Piché-Nicholas, Manoj Rajadhyaksha, Jennifer Liras, Alison Logan, Roberto A. Calle and Yan Weng
      Drug Metabolism and Disposition June 2015, 43 (6) 803-811; DOI: https://doi.org/10.1124/dmd.114.061713

  2. Grepper, Sue

    1. Prediction of Gestational Age–Dependent Induction of In Vivo Hepatic CYP3A Activity Based on HepaRG Cells and Human Hepatocytes
      Zufei Zhang, Muhammad Farooq, Bhagwat Prasad, Sue Grepper and Jashvant D. Unadkat
      Drug Metabolism and Disposition June 2015, 43 (6) 836-842; DOI: https://doi.org/10.1124/dmd.114.062984

  3. Guo, Yingying

    1. Prediction of In Vivo Clearance and Associated Variability of CYP2C19 Substrates by Genotypes in Populations Utilizing a Pharmacogenetics-Based Mechanistic Model
      Boyd Steere, Jessica A. Roseberry Baker, Stephen D. Hall and Yingying Guo
      Drug Metabolism and Disposition June 2015, 43 (6) 870-883; DOI: https://doi.org/10.1124/dmd.114.061523

H

  1. Hall, Stephen D.

    1. Prediction of In Vivo Clearance and Associated Variability of CYP2C19 Substrates by Genotypes in Populations Utilizing a Pharmacogenetics-Based Mechanistic Model
      Boyd Steere, Jessica A. Roseberry Baker, Stephen D. Hall and Yingying Guo
      Drug Metabolism and Disposition June 2015, 43 (6) 870-883; DOI: https://doi.org/10.1124/dmd.114.061523

  2. Halladay, Jason S.

    1. A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834
      Jasleen K. Sodhi, Susan Wong, Donald S. Kirkpatrick, Lichuan Liu, S. Cyrus Khojasteh, Cornelis E. C. A. Hop, John T. Barr, Jeffrey P. Jones and Jason S. Halladay
      Drug Metabolism and Disposition June 2015, 43 (6) 908-915; DOI: https://doi.org/10.1124/dmd.114.061804

  3. Hardwick, Rhiannon N.

    1. Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis
      Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington
      Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703

  4. Hentze, Hannes

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  5. Hesham A-Kader, H.

    1. Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis
      Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington
      Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703

  6. Hofmann, Ute

    1. Inflammation-Associated MicroRNA-130b Down-Regulates Cytochrome P450 Activities and Directly Targets CYP2C9
      Jessica K. Rieger, Sandra Reutter, Ute Hofmann, Matthias Schwab and Ulrich M. Zanger
      Drug Metabolism and Disposition June 2015, 43 (6) 884-888; DOI: https://doi.org/10.1124/dmd.114.062844

  7. Hop, Cornelis E. C. A.

    1. A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834
      Jasleen K. Sodhi, Susan Wong, Donald S. Kirkpatrick, Lichuan Liu, S. Cyrus Khojasteh, Cornelis E. C. A. Hop, John T. Barr, Jeffrey P. Jones and Jason S. Halladay
      Drug Metabolism and Disposition June 2015, 43 (6) 908-915; DOI: https://doi.org/10.1124/dmd.114.061804

  8. Hu, Dong Gui

    1. Induction of UDP-Glucuronosyltransferase 2B15 Gene Expression by the Major Active Metabolites of Tamoxifen, 4-Hydroxytamoxifen and Endoxifen, in Breast Cancer Cells
      Apichaya Chanawong, Dong Gui Hu, Robyn Meech, Peter I. Mackenzie and Ross A. McKinnon
      Drug Metabolism and Disposition June 2015, 43 (6) 889-897; DOI: https://doi.org/10.1124/dmd.114.062935

I

  1. Itoh, Tomoo

    1. Targeted Screen for Human UDP-Glucuronosyltransferases Inhibitors and the Evaluation of Potential Drug-Drug Interactions with Zafirlukast
      Shingo Oda, Ryoichi Fujiwara, Yuki Kutsuno, Tatsuki Fukami, Tomoo Itoh, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition June 2015, 43 (6) 812-818; DOI: https://doi.org/10.1124/dmd.114.062141

J

  1. Jones, Jeffrey P.

    1. A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834
      Jasleen K. Sodhi, Susan Wong, Donald S. Kirkpatrick, Lichuan Liu, S. Cyrus Khojasteh, Cornelis E. C. A. Hop, John T. Barr, Jeffrey P. Jones and Jason S. Halladay
      Drug Metabolism and Disposition June 2015, 43 (6) 908-915; DOI: https://doi.org/10.1124/dmd.114.061804

  2. Jusko, William J.

    1. Biodistribution of Etanercept to Tissues and Sites of Inflammation in Arthritic Rats
      Xi Chen, Debra C. DuBois, Richard R. Almon and William J. Jusko
      Drug Metabolism and Disposition June 2015, 43 (6) 898-907; DOI: https://doi.org/10.1124/dmd.114.062901

K

  1. Khojasteh, S. Cyrus

    1. A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834
      Jasleen K. Sodhi, Susan Wong, Donald S. Kirkpatrick, Lichuan Liu, S. Cyrus Khojasteh, Cornelis E. C. A. Hop, John T. Barr, Jeffrey P. Jones and Jason S. Halladay
      Drug Metabolism and Disposition June 2015, 43 (6) 908-915; DOI: https://doi.org/10.1124/dmd.114.061804

  2. Kirkpatrick, Donald S.

    1. A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834
      Jasleen K. Sodhi, Susan Wong, Donald S. Kirkpatrick, Lichuan Liu, S. Cyrus Khojasteh, Cornelis E. C. A. Hop, John T. Barr, Jeffrey P. Jones and Jason S. Halladay
      Drug Metabolism and Disposition June 2015, 43 (6) 908-915; DOI: https://doi.org/10.1124/dmd.114.061804

  3. Klümpen, Heinz-Josef

    1. Short-Term Fasting Alters Cytochrome P450–Mediated Drug Metabolism in Humans
      Laureen A. Lammers, Roos Achterbergh, Emmely M. de Vries, F. Samuel van Nierop, Heinz-Josef Klümpen, Maarten R. Soeters, Anita Boelen, Johannes A. Romijn and Ron A. A. Mathôt
      Drug Metabolism and Disposition June 2015, 43 (6) 819-828; DOI: https://doi.org/10.1124/dmd.114.062299

  4. Kutsuno, Yuki

    1. Targeted Screen for Human UDP-Glucuronosyltransferases Inhibitors and the Evaluation of Potential Drug-Drug Interactions with Zafirlukast
      Shingo Oda, Ryoichi Fujiwara, Yuki Kutsuno, Tatsuki Fukami, Tomoo Itoh, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition June 2015, 43 (6) 812-818; DOI: https://doi.org/10.1124/dmd.114.062141

L

  1. Lammers, Laureen A.

    1. Short-Term Fasting Alters Cytochrome P450–Mediated Drug Metabolism in Humans
      Laureen A. Lammers, Roos Achterbergh, Emmely M. de Vries, F. Samuel van Nierop, Heinz-Josef Klümpen, Maarten R. Soeters, Anita Boelen, Johannes A. Romijn and Ron A. A. Mathôt
      Drug Metabolism and Disposition June 2015, 43 (6) 819-828; DOI: https://doi.org/10.1124/dmd.114.062299

  2. Li, Jun

    1. Mechanistic Investigation of the Preclinical Pharmacokinetics and Interspecies Scaling of PF-05231023, a Fibroblast Growth Factor 21–Antibody Protein Conjugate
      Craig Giragossian, Chandra Vage, Jun Li, Kathleen Pelletier, Nicole Piché-Nicholas, Manoj Rajadhyaksha, Jennifer Liras, Alison Logan, Roberto A. Calle and Yan Weng
      Drug Metabolism and Disposition June 2015, 43 (6) 803-811; DOI: https://doi.org/10.1124/dmd.114.061713

  3. Liaw, Andy

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  4. Liras, Jennifer

    1. Mechanistic Investigation of the Preclinical Pharmacokinetics and Interspecies Scaling of PF-05231023, a Fibroblast Growth Factor 21–Antibody Protein Conjugate
      Craig Giragossian, Chandra Vage, Jun Li, Kathleen Pelletier, Nicole Piché-Nicholas, Manoj Rajadhyaksha, Jennifer Liras, Alison Logan, Roberto A. Calle and Yan Weng
      Drug Metabolism and Disposition June 2015, 43 (6) 803-811; DOI: https://doi.org/10.1124/dmd.114.061713

  5. Liu, Lichuan

    1. A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834
      Jasleen K. Sodhi, Susan Wong, Donald S. Kirkpatrick, Lichuan Liu, S. Cyrus Khojasteh, Cornelis E. C. A. Hop, John T. Barr, Jeffrey P. Jones and Jason S. Halladay
      Drug Metabolism and Disposition June 2015, 43 (6) 908-915; DOI: https://doi.org/10.1124/dmd.114.061804

  6. Logan, Alison

    1. Mechanistic Investigation of the Preclinical Pharmacokinetics and Interspecies Scaling of PF-05231023, a Fibroblast Growth Factor 21–Antibody Protein Conjugate
      Craig Giragossian, Chandra Vage, Jun Li, Kathleen Pelletier, Nicole Piché-Nicholas, Manoj Rajadhyaksha, Jennifer Liras, Alison Logan, Roberto A. Calle and Yan Weng
      Drug Metabolism and Disposition June 2015, 43 (6) 803-811; DOI: https://doi.org/10.1124/dmd.114.061713

  7. Ly, Justin

    1. Use of Transgenic Mouse Models to Understand the Oral Disposition and Drug-Drug Interaction Potential of Cobimetinib, a MEK Inhibitor
      Edna F. Choo, Sarah Woolsey, Kevin DeMent, Justin Ly, Kirsten Messick, Ann Qin and Ryan Takahashi
      Drug Metabolism and Disposition June 2015, 43 (6) 864-869; DOI: https://doi.org/10.1124/dmd.115.063743

M

  1. Mackenzie, Peter I.

    1. Induction of UDP-Glucuronosyltransferase 2B15 Gene Expression by the Major Active Metabolites of Tamoxifen, 4-Hydroxytamoxifen and Endoxifen, in Breast Cancer Cells
      Apichaya Chanawong, Dong Gui Hu, Robyn Meech, Peter I. Mackenzie and Ross A. McKinnon
      Drug Metabolism and Disposition June 2015, 43 (6) 889-897; DOI: https://doi.org/10.1124/dmd.114.062935

  2. Manautou, Jose E.

    1. Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis
      Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington
      Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703

  3. Mathôt, Ron A. A.

    1. Short-Term Fasting Alters Cytochrome P450–Mediated Drug Metabolism in Humans
      Laureen A. Lammers, Roos Achterbergh, Emmely M. de Vries, F. Samuel van Nierop, Heinz-Josef Klümpen, Maarten R. Soeters, Anita Boelen, Johannes A. Romijn and Ron A. A. Mathôt
      Drug Metabolism and Disposition June 2015, 43 (6) 819-828; DOI: https://doi.org/10.1124/dmd.114.062299

  4. McKinnon, Ross A.

    1. Induction of UDP-Glucuronosyltransferase 2B15 Gene Expression by the Major Active Metabolites of Tamoxifen, 4-Hydroxytamoxifen and Endoxifen, in Breast Cancer Cells
      Apichaya Chanawong, Dong Gui Hu, Robyn Meech, Peter I. Mackenzie and Ross A. McKinnon
      Drug Metabolism and Disposition June 2015, 43 (6) 889-897; DOI: https://doi.org/10.1124/dmd.114.062935

  5. Meech, Robyn

    1. Induction of UDP-Glucuronosyltransferase 2B15 Gene Expression by the Major Active Metabolites of Tamoxifen, 4-Hydroxytamoxifen and Endoxifen, in Breast Cancer Cells
      Apichaya Chanawong, Dong Gui Hu, Robyn Meech, Peter I. Mackenzie and Ross A. McKinnon
      Drug Metabolism and Disposition June 2015, 43 (6) 889-897; DOI: https://doi.org/10.1124/dmd.114.062935

  6. Merrell, Matthew D.

    1. Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis
      Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington
      Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703

  7. Messick, Kirsten

    1. Use of Transgenic Mouse Models to Understand the Oral Disposition and Drug-Drug Interaction Potential of Cobimetinib, a MEK Inhibitor
      Edna F. Choo, Sarah Woolsey, Kevin DeMent, Justin Ly, Kirsten Messick, Ann Qin and Ryan Takahashi
      Drug Metabolism and Disposition June 2015, 43 (6) 864-869; DOI: https://doi.org/10.1124/dmd.115.063743

N

  1. Nakajima, Miki

    1. Targeted Screen for Human UDP-Glucuronosyltransferases Inhibitors and the Evaluation of Potential Drug-Drug Interactions with Zafirlukast
      Shingo Oda, Ryoichi Fujiwara, Yuki Kutsuno, Tatsuki Fukami, Tomoo Itoh, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition June 2015, 43 (6) 812-818; DOI: https://doi.org/10.1124/dmd.114.062141

  2. Newton, Deborah

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  3. Ng, Choon Keow

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

O

  1. Oda, Shingo

    1. Targeted Screen for Human UDP-Glucuronosyltransferases Inhibitors and the Evaluation of Potential Drug-Drug Interactions with Zafirlukast
      Shingo Oda, Ryoichi Fujiwara, Yuki Kutsuno, Tatsuki Fukami, Tomoo Itoh, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition June 2015, 43 (6) 812-818; DOI: https://doi.org/10.1124/dmd.114.062141

  2. Owens, Karen

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

P

  1. Palamanda, Jairam

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  2. Pelletier, Kathleen

    1. Mechanistic Investigation of the Preclinical Pharmacokinetics and Interspecies Scaling of PF-05231023, a Fibroblast Growth Factor 21–Antibody Protein Conjugate
      Craig Giragossian, Chandra Vage, Jun Li, Kathleen Pelletier, Nicole Piché-Nicholas, Manoj Rajadhyaksha, Jennifer Liras, Alison Logan, Roberto A. Calle and Yan Weng
      Drug Metabolism and Disposition June 2015, 43 (6) 803-811; DOI: https://doi.org/10.1124/dmd.114.061713

  3. Piché-Nicholas, Nicole

    1. Mechanistic Investigation of the Preclinical Pharmacokinetics and Interspecies Scaling of PF-05231023, a Fibroblast Growth Factor 21–Antibody Protein Conjugate
      Craig Giragossian, Chandra Vage, Jun Li, Kathleen Pelletier, Nicole Piché-Nicholas, Manoj Rajadhyaksha, Jennifer Liras, Alison Logan, Roberto A. Calle and Yan Weng
      Drug Metabolism and Disposition June 2015, 43 (6) 803-811; DOI: https://doi.org/10.1124/dmd.114.061713

  4. Prasad, Bhagwat

    1. Prediction of Gestational Age–Dependent Induction of In Vivo Hepatic CYP3A Activity Based on HepaRG Cells and Human Hepatocytes
      Zufei Zhang, Muhammad Farooq, Bhagwat Prasad, Sue Grepper and Jashvant D. Unadkat
      Drug Metabolism and Disposition June 2015, 43 (6) 836-842; DOI: https://doi.org/10.1124/dmd.114.062984

Q

  1. Qin, Ann

    1. Use of Transgenic Mouse Models to Understand the Oral Disposition and Drug-Drug Interaction Potential of Cobimetinib, a MEK Inhibitor
      Edna F. Choo, Sarah Woolsey, Kevin DeMent, Justin Ly, Kirsten Messick, Ann Qin and Ryan Takahashi
      Drug Metabolism and Disposition June 2015, 43 (6) 864-869; DOI: https://doi.org/10.1124/dmd.115.063743

R

  1. Rajadhyaksha, Manoj

    1. Mechanistic Investigation of the Preclinical Pharmacokinetics and Interspecies Scaling of PF-05231023, a Fibroblast Growth Factor 21–Antibody Protein Conjugate
      Craig Giragossian, Chandra Vage, Jun Li, Kathleen Pelletier, Nicole Piché-Nicholas, Manoj Rajadhyaksha, Jennifer Liras, Alison Logan, Roberto A. Calle and Yan Weng
      Drug Metabolism and Disposition June 2015, 43 (6) 803-811; DOI: https://doi.org/10.1124/dmd.114.061713

  2. Reutter, Sandra

    1. Inflammation-Associated MicroRNA-130b Down-Regulates Cytochrome P450 Activities and Directly Targets CYP2C9
      Jessica K. Rieger, Sandra Reutter, Ute Hofmann, Matthias Schwab and Ulrich M. Zanger
      Drug Metabolism and Disposition June 2015, 43 (6) 884-888; DOI: https://doi.org/10.1124/dmd.114.062844

  3. Rieger, Jessica K.

    1. Inflammation-Associated MicroRNA-130b Down-Regulates Cytochrome P450 Activities and Directly Targets CYP2C9
      Jessica K. Rieger, Sandra Reutter, Ute Hofmann, Matthias Schwab and Ulrich M. Zanger
      Drug Metabolism and Disposition June 2015, 43 (6) 884-888; DOI: https://doi.org/10.1124/dmd.114.062844

  4. Romijn, Johannes A.

    1. Short-Term Fasting Alters Cytochrome P450–Mediated Drug Metabolism in Humans
      Laureen A. Lammers, Roos Achterbergh, Emmely M. de Vries, F. Samuel van Nierop, Heinz-Josef Klümpen, Maarten R. Soeters, Anita Boelen, Johannes A. Romijn and Ron A. A. Mathôt
      Drug Metabolism and Disposition June 2015, 43 (6) 819-828; DOI: https://doi.org/10.1124/dmd.114.062299

S

  1. Salituro, Gino

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  2. Savage, Mary J.

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  3. Schwab, Matthias

    1. Inflammation-Associated MicroRNA-130b Down-Regulates Cytochrome P450 Activities and Directly Targets CYP2C9
      Jessica K. Rieger, Sandra Reutter, Ute Hofmann, Matthias Schwab and Ulrich M. Zanger
      Drug Metabolism and Disposition June 2015, 43 (6) 884-888; DOI: https://doi.org/10.1124/dmd.114.062844

  4. Shaw, Rachel

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  5. Shih, Shian-Jiun

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  6. Sodhi, Jasleen K.

    1. A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834
      Jasleen K. Sodhi, Susan Wong, Donald S. Kirkpatrick, Lichuan Liu, S. Cyrus Khojasteh, Cornelis E. C. A. Hop, John T. Barr, Jeffrey P. Jones and Jason S. Halladay
      Drug Metabolism and Disposition June 2015, 43 (6) 908-915; DOI: https://doi.org/10.1124/dmd.114.061804

  7. Soeters, Maarten R.

    1. Short-Term Fasting Alters Cytochrome P450–Mediated Drug Metabolism in Humans
      Laureen A. Lammers, Roos Achterbergh, Emmely M. de Vries, F. Samuel van Nierop, Heinz-Josef Klümpen, Maarten R. Soeters, Anita Boelen, Johannes A. Romijn and Ron A. A. Mathôt
      Drug Metabolism and Disposition June 2015, 43 (6) 819-828; DOI: https://doi.org/10.1124/dmd.114.062299

  8. Squirewell, Edwin J.

    1. The Effects of Endoxifen and Other Major Metabolites of Tamoxifen on the Sulfation of Estradiol Catalyzed by Human Cytosolic Sulfotransferases hSULT1E1 and hSULT1A1*1
      Edwin J. Squirewell and Michael W. Duffel
      Drug Metabolism and Disposition June 2015, 43 (6) 843-850; DOI: https://doi.org/10.1124/dmd.115.063206

  9. Steere, Boyd

    1. Prediction of In Vivo Clearance and Associated Variability of CYP2C19 Substrates by Genotypes in Populations Utilizing a Pharmacogenetics-Based Mechanistic Model
      Boyd Steere, Jessica A. Roseberry Baker, Stephen D. Hall and Yingying Guo
      Drug Metabolism and Disposition June 2015, 43 (6) 870-883; DOI: https://doi.org/10.1124/dmd.114.061523

T

  1. Takahashi, Ryan

    1. Use of Transgenic Mouse Models to Understand the Oral Disposition and Drug-Drug Interaction Potential of Cobimetinib, a MEK Inhibitor
      Edna F. Choo, Sarah Woolsey, Kevin DeMent, Justin Ly, Kirsten Messick, Ann Qin and Ryan Takahashi
      Drug Metabolism and Disposition June 2015, 43 (6) 864-869; DOI: https://doi.org/10.1124/dmd.115.063743

U

  1. Unadkat, Jashvant D.

    1. Prediction of Gestational Age–Dependent Induction of In Vivo Hepatic CYP3A Activity Based on HepaRG Cells and Human Hepatocytes
      Zufei Zhang, Muhammad Farooq, Bhagwat Prasad, Sue Grepper and Jashvant D. Unadkat
      Drug Metabolism and Disposition June 2015, 43 (6) 836-842; DOI: https://doi.org/10.1124/dmd.114.062984

V

  1. Vage, Chandra

    1. Mechanistic Investigation of the Preclinical Pharmacokinetics and Interspecies Scaling of PF-05231023, a Fibroblast Growth Factor 21–Antibody Protein Conjugate
      Craig Giragossian, Chandra Vage, Jun Li, Kathleen Pelletier, Nicole Piché-Nicholas, Manoj Rajadhyaksha, Jennifer Liras, Alison Logan, Roberto A. Calle and Yan Weng
      Drug Metabolism and Disposition June 2015, 43 (6) 803-811; DOI: https://doi.org/10.1124/dmd.114.061713

  2. van Nierop, F. Samuel

    1. Short-Term Fasting Alters Cytochrome P450–Mediated Drug Metabolism in Humans
      Laureen A. Lammers, Roos Achterbergh, Emmely M. de Vries, F. Samuel van Nierop, Heinz-Josef Klümpen, Maarten R. Soeters, Anita Boelen, Johannes A. Romijn and Ron A. A. Mathôt
      Drug Metabolism and Disposition June 2015, 43 (6) 819-828; DOI: https://doi.org/10.1124/dmd.114.062299

W

  1. Wang, Shubing

    1. Evaluation of Cynomolgus Monkeys for the Identification of Endogenous Biomarkers for Hepatic Transporter Inhibition and as a Translatable Model to Predict Pharmacokinetic Interactions with Statins in Humans
      Xiaoyan Chu, Shian-Jiun Shih, Rachel Shaw, Hannes Hentze, Grace H. Chan, Karen Owens, Shubing Wang, Xiaoxin Cai, Deborah Newton, Jose Castro-Perez, Gino Salituro, Jairam Palamanda, Aaron Fernandis, Choon Keow Ng, Andy Liaw, Mary J. Savage and Raymond Evers
      Drug Metabolism and Disposition June 2015, 43 (6) 851-863; DOI: https://doi.org/10.1124/dmd.115.063347

  2. Weng, Yan

    1. Mechanistic Investigation of the Preclinical Pharmacokinetics and Interspecies Scaling of PF-05231023, a Fibroblast Growth Factor 21–Antibody Protein Conjugate
      Craig Giragossian, Chandra Vage, Jun Li, Kathleen Pelletier, Nicole Piché-Nicholas, Manoj Rajadhyaksha, Jennifer Liras, Alison Logan, Roberto A. Calle and Yan Weng
      Drug Metabolism and Disposition June 2015, 43 (6) 803-811; DOI: https://doi.org/10.1124/dmd.114.061713

  3. Wong, Susan

    1. A Novel Reaction Mediated by Human Aldehyde Oxidase: Amide Hydrolysis of GDC-0834
      Jasleen K. Sodhi, Susan Wong, Donald S. Kirkpatrick, Lichuan Liu, S. Cyrus Khojasteh, Cornelis E. C. A. Hop, John T. Barr, Jeffrey P. Jones and Jason S. Halladay
      Drug Metabolism and Disposition June 2015, 43 (6) 908-915; DOI: https://doi.org/10.1124/dmd.114.061804

  4. Woolsey, Sarah

    1. Use of Transgenic Mouse Models to Understand the Oral Disposition and Drug-Drug Interaction Potential of Cobimetinib, a MEK Inhibitor
      Edna F. Choo, Sarah Woolsey, Kevin DeMent, Justin Ly, Kirsten Messick, Ann Qin and Ryan Takahashi
      Drug Metabolism and Disposition June 2015, 43 (6) 864-869; DOI: https://doi.org/10.1124/dmd.115.063743

X

  1. Xanthakos, Stavra A.

    1. Altered Regulation of Hepatic Efflux Transporters Disrupts Acetaminophen Disposition in Pediatric Nonalcoholic Steatohepatitis
      Mark J. Canet, Matthew D. Merrell, Rhiannon N. Hardwick, Amy M. Bataille, Sarah N. Campion, Daniel W. Ferreira, Stavra A. Xanthakos, Jose E. Manautou, H. Hesham A-Kader, Robert P. Erickson and Nathan J. Cherrington
      Drug Metabolism and Disposition June 2015, 43 (6) 829-835; DOI: https://doi.org/10.1124/dmd.114.062703

Y

  1. Yokoi, Tsuyoshi

    1. Targeted Screen for Human UDP-Glucuronosyltransferases Inhibitors and the Evaluation of Potential Drug-Drug Interactions with Zafirlukast
      Shingo Oda, Ryoichi Fujiwara, Yuki Kutsuno, Tatsuki Fukami, Tomoo Itoh, Tsuyoshi Yokoi and Miki Nakajima
      Drug Metabolism and Disposition June 2015, 43 (6) 812-818; DOI: https://doi.org/10.1124/dmd.114.062141

Z

  1. Zanger, Ulrich M.

    1. Inflammation-Associated MicroRNA-130b Down-Regulates Cytochrome P450 Activities and Directly Targets CYP2C9
      Jessica K. Rieger, Sandra Reutter, Ute Hofmann, Matthias Schwab and Ulrich M. Zanger
      Drug Metabolism and Disposition June 2015, 43 (6) 884-888; DOI: https://doi.org/10.1124/dmd.114.062844

  2. Zhang, Zufei

    1. Prediction of Gestational Age–Dependent Induction of In Vivo Hepatic CYP3A Activity Based on HepaRG Cells and Human Hepatocytes
      Zufei Zhang, Muhammad Farooq, Bhagwat Prasad, Sue Grepper and Jashvant D. Unadkat
      Drug Metabolism and Disposition June 2015, 43 (6) 836-842; DOI: https://doi.org/10.1124/dmd.114.062984
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