Index by author
July 01, 2015; Volume 43,Issue 7
A
Addepalli, Balasubrahmanyam
- You have accessChimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve ChemosensitivityMei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming YuDrug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493
An, Gang
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
B
Babiskin, Andrew
- You have accessMetabolism of Bupropion by Carbonyl Reductases in Liver and IntestineJamie N. Connarn, Xinyuan Zhang, Andrew Babiskin and Duxin SunDrug Metabolism and Disposition July 2015, 43 (7) 1019-1027; DOI: https://doi.org/10.1124/dmd.115.063107
Bacon, James
- You have accessEthnic Variability in the Expression of Hepatic Drug Transporters: Absolute Quantification by an Optimized Targeted Quantitative Proteomic ApproachKuan-wei Peng, James Bacon, Ming Zheng, Yingying Guo and Michael Zhuo WangDrug Metabolism and Disposition July 2015, 43 (7) 1045-1055; DOI: https://doi.org/10.1124/dmd.115.063362
Barrett, Kathleen G.
- You have accessUpregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid ConjugationKathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-MorrisDrug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440
Bi, Yi-an
- You have accessQuantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-GlucuronideManthena V. S. Varma, Jian Lin, Yi-an Bi, Emi Kimoto and A. David RodriguesDrug Metabolism and Disposition July 2015, 43 (7) 1108-1118; DOI: https://doi.org/10.1124/dmd.115.064303
Blanco, Javier G.
- You have accessCharacterization of the Canine Anthracycline-Metabolizing Enzyme Carbonyl Reductase 1 (cbr1) and the Functional Isoform cbr1 V218Daniel C. Ferguson, Qiuying Cheng and Javier G. BlancoDrug Metabolism and Disposition July 2015, 43 (7) 922-927; DOI: https://doi.org/10.1124/dmd.115.064295
Bott, Debbie
- You have accessRelative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult MiceShuang Wang, Debbie Bott, Aveline Tung, Kim S. Sugamori and Denis M. GrantDrug Metabolism and Disposition July 2015, 43 (7) 916-921; DOI: https://doi.org/10.1124/dmd.115.063297
C
Calinski, Diane M.
- You have accessHydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring PolymorphismsDiane M. Calinski, Haoming Zhang, Susan Ludeman, M. Eileen Dolan and Paul F. HollenbergDrug Metabolism and Disposition July 2015, 43 (7) 1084-1090; DOI: https://doi.org/10.1124/dmd.115.063628
Chabowski, Adrian
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Chang, Chia-Yu
- You have accessThe Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated InhibitionSheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang UengDrug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966
Cheatham, Bentley
- You have accessPharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal ImpairmentRobin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. WilkisonDrug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828
Chen, Cliff
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Chen, Qiu-Xia
- You have accessChimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve ChemosensitivityMei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming YuDrug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493
Cheng, Qiuying
- You have accessCharacterization of the Canine Anthracycline-Metabolizing Enzyme Carbonyl Reductase 1 (cbr1) and the Functional Isoform cbr1 V218Daniel C. Ferguson, Qiuying Cheng and Javier G. BlancoDrug Metabolism and Disposition July 2015, 43 (7) 922-927; DOI: https://doi.org/10.1124/dmd.115.064295
Chesworth, Richard
- You have accessStructural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. WatersDrug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014
Chlopicki, Stefan
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Christopher, Lisa J.
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Connarn, Jamie N.
- You have accessMetabolism of Bupropion by Carbonyl Reductases in Liver and IntestineJamie N. Connarn, Xinyuan Zhang, Andrew Babiskin and Duxin SunDrug Metabolism and Disposition July 2015, 43 (7) 1019-1027; DOI: https://doi.org/10.1124/dmd.115.063107
Copeland, Robert A.
- You have accessStructural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. WatersDrug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014
Crittenden, Frank
- You have accessActivity Suppression Behavior Phenotype in SULT4A1 Frameshift Mutant ZebrafishFrank Crittenden, Holly R. Thomas, John M. Parant and Charles N. FalanyDrug Metabolism and Disposition July 2015, 43 (7) 1037-1044; DOI: https://doi.org/10.1124/dmd.115.064485
Csanaky, Iván L.
- You have accessMultidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of DiclofenacRenato J. Scialis, Iván L. Csanaky, Michael J. Goedken and José E. ManautouDrug Metabolism and Disposition July 2015, 43 (7) 944-950; DOI: https://doi.org/10.1124/dmd.114.061705
Cukovic, Daniela
- You have accessUpregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid ConjugationKathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-MorrisDrug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440
D
Dai, Peimin
- You have accessUDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver MicrosomesLijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
Deshmukh, Gauri
- You have accessUse of Cassette Dosing to Enhance the Throughput of Rat Brain Microdialysis StudiesGauri Deshmukh, Kefeng Sun, Bianca M. Liederer, Xiao Ding and Xingrong LiuDrug Metabolism and Disposition July 2015, 43 (7) 1123-1128; DOI: https://doi.org/10.1124/dmd.115.064204
Ding, Xiao
- You have accessUse of Cassette Dosing to Enhance the Throughput of Rat Brain Microdialysis StudiesGauri Deshmukh, Kefeng Sun, Bianca M. Liederer, Xiao Ding and Xingrong LiuDrug Metabolism and Disposition July 2015, 43 (7) 1123-1128; DOI: https://doi.org/10.1124/dmd.115.064204
Dobbins, Robert L.
- You have accessPharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal ImpairmentRobin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. WilkisonDrug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828
Dolan, M. Eileen
- You have accessHydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring PolymorphismsDiane M. Calinski, Haoming Zhang, Susan Ludeman, M. Eileen Dolan and Paul F. HollenbergDrug Metabolism and Disposition July 2015, 43 (7) 1084-1090; DOI: https://doi.org/10.1124/dmd.115.063628
Dombkowski, Alan A.
- You have accessUpregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid ConjugationKathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-MorrisDrug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440
Dyer, Rachel L.
- You have accessMetabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver BioreactorUjjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. TannenbaumDrug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495
E
Ebrahimkhani, Mohammad R.
- You have accessMetabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver BioreactorUjjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. TannenbaumDrug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495
F
Falany, Charles N.
- You have accessActivity Suppression Behavior Phenotype in SULT4A1 Frameshift Mutant ZebrafishFrank Crittenden, Holly R. Thomas, John M. Parant and Charles N. FalanyDrug Metabolism and Disposition July 2015, 43 (7) 1037-1044; DOI: https://doi.org/10.1124/dmd.115.064485
Fang, Hailin
- You have accessUpregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid ConjugationKathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-MorrisDrug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440
Ferguson, Daniel C.
- You have accessCharacterization of the Canine Anthracycline-Metabolizing Enzyme Carbonyl Reductase 1 (cbr1) and the Functional Isoform cbr1 V218Daniel C. Ferguson, Qiuying Cheng and Javier G. BlancoDrug Metabolism and Disposition July 2015, 43 (7) 922-927; DOI: https://doi.org/10.1124/dmd.115.064295
Friedel, Christina
- You have accessDifferences in Methadone Metabolism by CYP2B6 VariantsSarah Gadel, Christina Friedel and Evan D. KharaschDrug Metabolism and Disposition July 2015, 43 (7) 994-1001; DOI: https://doi.org/10.1124/dmd.115.064352
Frost, Kerry
- You have accessStructural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. WatersDrug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014
Fujiwara, Ryoichi
- You have accessExpression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse BrainYuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi FujiwaraDrug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719
Fukami, Tatsuki
- You have accessCarbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in RatsAzumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370
G
Gadel, Sarah
- You have accessDifferences in Methadone Metabolism by CYP2B6 VariantsSarah Gadel, Christina Friedel and Evan D. KharaschDrug Metabolism and Disposition July 2015, 43 (7) 994-1001; DOI: https://doi.org/10.1124/dmd.115.064352
Goedken, Michael J.
- You have accessMultidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of DiclofenacRenato J. Scialis, Iván L. Csanaky, Michael J. Goedken and José E. ManautouDrug Metabolism and Disposition July 2015, 43 (7) 944-950; DOI: https://doi.org/10.1124/dmd.114.061705
Gonciarz-Dytman, Anna
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Grant, Denis M.
- You have accessRelative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult MiceShuang Wang, Debbie Bott, Aveline Tung, Kim S. Sugamori and Denis M. GrantDrug Metabolism and Disposition July 2015, 43 (7) 916-921; DOI: https://doi.org/10.1124/dmd.115.063297
Griffith, Linda G.
- You have accessMetabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver BioreactorUjjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. TannenbaumDrug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495
Guo, Yingying
- You have accessEthnic Variability in the Expression of Hepatic Drug Transporters: Absolute Quantification by an Optimized Targeted Quantitative Proteomic ApproachKuan-wei Peng, James Bacon, Ming Zheng, Yingying Guo and Michael Zhuo WangDrug Metabolism and Disposition July 2015, 43 (7) 1045-1055; DOI: https://doi.org/10.1124/dmd.115.063362
H
He, Enuo
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Hirashima, Rika
- You have accessExpression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse BrainYuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi FujiwaraDrug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719
Holland, Ryan J.
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Hollenberg, Paul F.
- You have accessHydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring PolymorphismsDiane M. Calinski, Haoming Zhang, Susan Ludeman, M. Eileen Dolan and Paul F. HollenbergDrug Metabolism and Disposition July 2015, 43 (7) 1084-1090; DOI: https://doi.org/10.1124/dmd.115.063628
Hosaka, Shinya
- You have accessComprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz OxidaseShinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925
House, Larry K.
- You have accessGlucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10Jacqueline Ramírez, Snezana Mirkov, Larry K. House and Mark J. RatainDrug Metabolism and Disposition July 2015, 43 (7) 928-935; DOI: https://doi.org/10.1124/dmd.115.063271
Hu, Ming
- You have accessUDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver MicrosomesLijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
Huang, Chiung-Chiao
- You have accessThe Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated InhibitionSheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang UengDrug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966
Huang, Min
- You have accessChimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve ChemosensitivityMei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming YuDrug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493
Hughes, David J.
- You have accessMetabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver BioreactorUjjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. TannenbaumDrug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495
Hussey, Elizabeth K.
- You have accessPharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal ImpairmentRobin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. WilkisonDrug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828
I
Iida, Azumi
- You have accessCarbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in RatsAzumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370
Inoue, Takashi
- You have accessSubstrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 969-976; DOI: https://doi.org/10.1124/dmd.115.063909
Ito, Sumito
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Itoh, Tomoo
- You have accessExpression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse BrainYuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi FujiwaraDrug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719
Iwano, Shunsuke
- You have accessComprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz OxidaseShinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925
Iwasaki, Kazuhide
- You have accessComprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz OxidaseShinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925
J
Jeong, Hyunyoung
- You have accessFarnesoid X Receptor Agonist Represses Cytochrome P450 2D6 Expression by Upregulating Small Heterodimer PartnerXian Pan, Yoon-Kwang Lee and Hyunyoung JeongDrug Metabolism and Disposition July 2015, 43 (7) 1002-1007; DOI: https://doi.org/10.1124/dmd.115.064758
Ji, Hyeon-Kyeong
- You have accessSimultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5′-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography–Tandem Mass SpectrometryBoram Lee, Hyeon-Kyeong Ji, Taeho Lee and Kwang-Hyeon LiuDrug Metabolism and Disposition July 2015, 43 (7) 1137-1146; DOI: https://doi.org/10.1124/dmd.114.063016
K
Kapur, Anita
- You have accessPharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal ImpairmentRobin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. WilkisonDrug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828
Keefer, Larry K.
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Kharasch, Evan D.
- You have accessDifferences in Methadone Metabolism by CYP2B6 VariantsSarah Gadel, Christina Friedel and Evan D. KharaschDrug Metabolism and Disposition July 2015, 43 (7) 994-1001; DOI: https://doi.org/10.1124/dmd.115.064352
Kij, Agnieszka
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Kimoto, Emi
- You have accessQuantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-GlucuronideManthena V. S. Varma, Jian Lin, Yi-an Bi, Emi Kimoto and A. David RodriguesDrug Metabolism and Disposition July 2015, 43 (7) 1108-1118; DOI: https://doi.org/10.1124/dmd.115.064303
Kocarek, Thomas A.
- You have accessUpregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid ConjugationKathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-MorrisDrug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440
Kus, Kamil
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Kusuhara, Hiroyuki
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Kutsuno, Yuki
- You have accessExpression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse BrainYuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi FujiwaraDrug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719
L
Lai, Yurong
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Large, Emma M.
- You have accessMetabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver BioreactorUjjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. TannenbaumDrug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495
LaSalle, Janine M.
- You have accessChimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve ChemosensitivityMei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming YuDrug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493
Lee, Boram
- You have accessSimultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5′-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography–Tandem Mass SpectrometryBoram Lee, Hyeon-Kyeong Ji, Taeho Lee and Kwang-Hyeon LiuDrug Metabolism and Disposition July 2015, 43 (7) 1137-1146; DOI: https://doi.org/10.1124/dmd.114.063016
Lee, Taeho
- You have accessSimultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5′-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography–Tandem Mass SpectrometryBoram Lee, Hyeon-Kyeong Ji, Taeho Lee and Kwang-Hyeon LiuDrug Metabolism and Disposition July 2015, 43 (7) 1137-1146; DOI: https://doi.org/10.1124/dmd.114.063016
Lee, Yoon-Kwang
- You have accessFarnesoid X Receptor Agonist Represses Cytochrome P450 2D6 Expression by Upregulating Small Heterodimer PartnerXian Pan, Yoon-Kwang Lee and Hyunyoung JeongDrug Metabolism and Disposition July 2015, 43 (7) 1002-1007; DOI: https://doi.org/10.1124/dmd.115.064758
Lewin, Anne C.
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Li, Mei-Mei
- You have accessChimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve ChemosensitivityMei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming YuDrug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493
Li, Yang
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Liederer, Bianca M.
- You have accessUse of Cassette Dosing to Enhance the Throughput of Rat Brain Microdialysis StudiesGauri Deshmukh, Kefeng Sun, Bianca M. Liederer, Xiao Ding and Xingrong LiuDrug Metabolism and Disposition July 2015, 43 (7) 1123-1128; DOI: https://doi.org/10.1124/dmd.115.064204
Limbach, Patrick A.
- You have accessChimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve ChemosensitivityMei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming YuDrug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493
Lin, Jian
- You have accessQuantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-GlucuronideManthena V. S. Varma, Jian Lin, Yi-an Bi, Emi Kimoto and A. David RodriguesDrug Metabolism and Disposition July 2015, 43 (7) 1108-1118; DOI: https://doi.org/10.1124/dmd.115.064303
Liu, Guowen
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Liu, Houfu
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Liu, Kwang-Hyeon
- You have accessSimultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5′-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography–Tandem Mass SpectrometryBoram Lee, Hyeon-Kyeong Ji, Taeho Lee and Kwang-Hyeon LiuDrug Metabolism and Disposition July 2015, 43 (7) 1137-1146; DOI: https://doi.org/10.1124/dmd.114.063016
Liu, Liang
- You have accessUDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver MicrosomesLijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
Liu, Tongtong
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Liu, Xingrong
- You have accessUse of Cassette Dosing to Enhance the Throughput of Rat Brain Microdialysis StudiesGauri Deshmukh, Kefeng Sun, Bianca M. Liederer, Xiao Ding and Xingrong LiuDrug Metabolism and Disposition July 2015, 43 (7) 1123-1128; DOI: https://doi.org/10.1124/dmd.115.064204
Liu, Zhongqiu
- You have accessUDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver MicrosomesLijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
Lo, Sheng-Nan
- You have accessThe Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated InhibitionSheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang UengDrug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966
Lu, Linlin
- You have accessUDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver MicrosomesLijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
Lu, Sijie
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Lu, Xinyan
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Ludeman, Susan
- You have accessHydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring PolymorphismsDiane M. Calinski, Haoming Zhang, Susan Ludeman, M. Eileen Dolan and Paul F. HollenbergDrug Metabolism and Disposition July 2015, 43 (7) 1084-1090; DOI: https://doi.org/10.1124/dmd.115.063628
Luo, Feifei
- You have accessUDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver MicrosomesLijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
M
Manautou, José E.
- You have accessMultidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of DiclofenacRenato J. Scialis, Iván L. Csanaky, Michael J. Goedken and José E. ManautouDrug Metabolism and Disposition July 2015, 43 (7) 944-950; DOI: https://doi.org/10.1124/dmd.114.061705
Marathe, Punit
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Maslak, Edyta
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Mehvar, Reza
- You have accessFractional Clearance for Verapamil N-Demethylation in the Isolated Rat Liver PreparationReza MehvarDrug Metabolism and Disposition July 2015, 43 (7) 1056-1057; DOI: https://doi.org/10.1124/dmd.115.064691
Michimae, Hirofumi
- You have accessExpression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse BrainYuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi FujiwaraDrug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719
Mirkov, Snezana
- You have accessGlucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10Jacqueline Ramírez, Snezana Mirkov, Larry K. House and Mark J. RatainDrug Metabolism and Disposition July 2015, 43 (7) 928-935; DOI: https://doi.org/10.1124/dmd.115.063271
Mitchell, Lorna H.
- You have accessStructural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. WatersDrug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014
Morse, Bridget L.
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Moyer, Mikel P.
- You have accessStructural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. WatersDrug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014
Murayama, Norie
- You have accessComprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz OxidaseShinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925
N
Nakajima, Miki
- You have accessCarbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in RatsAzumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370
O
O’Connor-Semmes, Robin
- You have accessPharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal ImpairmentRobin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. WilkisonDrug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828
P
Pan, Xian
- You have accessFarnesoid X Receptor Agonist Represses Cytochrome P450 2D6 Expression by Upregulating Small Heterodimer PartnerXian Pan, Yoon-Kwang Lee and Hyunyoung JeongDrug Metabolism and Disposition July 2015, 43 (7) 1002-1007; DOI: https://doi.org/10.1124/dmd.115.064758
Pang, K. Sandy
- You have accessResponse to Letter to the Editor on “Fractional Clearance for Verapamil N-Demethylation in the Isolated Rat Liver Preparation”K. Sandy Pang and Qi Joy YangDrug Metabolism and Disposition July 2015, 43 (7) 1058-1059; DOI: https://doi.org/10.1124/dmd.115.065227
Parant, John M.
- You have accessActivity Suppression Behavior Phenotype in SULT4A1 Frameshift Mutant ZebrafishFrank Crittenden, Holly R. Thomas, John M. Parant and Charles N. FalanyDrug Metabolism and Disposition July 2015, 43 (7) 1037-1044; DOI: https://doi.org/10.1124/dmd.115.064485
Peng, Kuan-wei
- You have accessEthnic Variability in the Expression of Hepatic Drug Transporters: Absolute Quantification by an Optimized Targeted Quantitative Proteomic ApproachKuan-wei Peng, James Bacon, Ming Zheng, Yingying Guo and Michael Zhuo WangDrug Metabolism and Disposition July 2015, 43 (7) 1045-1055; DOI: https://doi.org/10.1124/dmd.115.063362
Petrovic, Vanja
- You have accessPolyinosinic/Polycytidylic Acid–Mediated Changes in Maternal and Fetal Disposition of Lopinavir in RatsVanja Petrovic and Micheline Piquette-MillerDrug Metabolism and Disposition July 2015, 43 (7) 951-957; DOI: https://doi.org/10.1124/dmd.114.062315
Piquette-Miller, Micheline
- You have accessPolyinosinic/Polycytidylic Acid–Mediated Changes in Maternal and Fetal Disposition of Lopinavir in RatsVanja Petrovic and Micheline Piquette-MillerDrug Metabolism and Disposition July 2015, 43 (7) 951-957; DOI: https://doi.org/10.1124/dmd.114.062315
Plant, Katie
- You have accessStructural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. WatersDrug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014
Prasad, Bhagwat
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Q
Qiu, Xi
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
R
Ramírez, Jacqueline
- You have accessGlucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10Jacqueline Ramírez, Snezana Mirkov, Larry K. House and Mark J. RatainDrug Metabolism and Disposition July 2015, 43 (7) 928-935; DOI: https://doi.org/10.1124/dmd.115.063271
Ratain, Mark J.
- You have accessGlucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10Jacqueline Ramírez, Snezana Mirkov, Larry K. House and Mark J. RatainDrug Metabolism and Disposition July 2015, 43 (7) 928-935; DOI: https://doi.org/10.1124/dmd.115.063271
Ravindra, Kodihalli C.
- You have accessMetabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver BioreactorUjjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. TannenbaumDrug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495
Ribich, Scott
- You have accessStructural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. WatersDrug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014
Rioux, Nathalie
- You have accessStructural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. WatersDrug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014
Rivera-Burgos, Dinelia
- You have accessMetabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver BioreactorUjjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. TannenbaumDrug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495
Rodrigues, A. David
- You have accessQuantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-GlucuronideManthena V. S. Varma, Jian Lin, Yi-an Bi, Emi Kimoto and A. David RodriguesDrug Metabolism and Disposition July 2015, 43 (7) 1108-1118; DOI: https://doi.org/10.1124/dmd.115.064303
Runge-Morris, Melissa
- You have accessUpregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid ConjugationKathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-MorrisDrug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440
S
Saavedra, Joseph E.
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Sahi, Jasminder
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Sakamoto, Masaya
- You have accessExpression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse BrainYuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi FujiwaraDrug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719
Sarkar, Ujjal
- You have accessMetabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver BioreactorUjjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. TannenbaumDrug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495
Sasaki, Eita
- You have accessCarbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in RatsAzumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370
Sasaki, Erika
- You have accessSubstrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 969-976; DOI: https://doi.org/10.1124/dmd.115.063909
Satsukawa, Masahiro
- You have accessComprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz OxidaseShinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925
Scialis, Renato J.
- You have accessMultidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of DiclofenacRenato J. Scialis, Iván L. Csanaky, Michael J. Goedken and José E. ManautouDrug Metabolism and Disposition July 2015, 43 (7) 944-950; DOI: https://doi.org/10.1124/dmd.114.061705
Shaw, Joanne
- You have accessStructural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. WatersDrug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014
Shen, Chien-Chang
- You have accessThe Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated InhibitionSheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang UengDrug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966
Shen, Hong
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Shimizu, Makiko
- You have accessComprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz OxidaseShinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925
Sitek, Barbara
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Sugamori, Kim S.
- You have accessRelative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult MiceShuang Wang, Debbie Bott, Aveline Tung, Kim S. Sugamori and Denis M. GrantDrug Metabolism and Disposition July 2015, 43 (7) 916-921; DOI: https://doi.org/10.1124/dmd.115.063297
Sugiyama, Yuichi
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Sun, Duxin
- You have accessMetabolism of Bupropion by Carbonyl Reductases in Liver and IntestineJamie N. Connarn, Xinyuan Zhang, Andrew Babiskin and Duxin SunDrug Metabolism and Disposition July 2015, 43 (7) 1019-1027; DOI: https://doi.org/10.1124/dmd.115.063107
Sun, Kefeng
- You have accessUse of Cassette Dosing to Enhance the Throughput of Rat Brain Microdialysis StudiesGauri Deshmukh, Kefeng Sun, Bianca M. Liederer, Xiao Ding and Xingrong LiuDrug Metabolism and Disposition July 2015, 43 (7) 1123-1128; DOI: https://doi.org/10.1124/dmd.115.064204
T
Tan, Qing-Rong
- You have accessPeony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro ModelsWei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin ZhangDrug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653
Tannenbaum, Steven R.
- You have accessMetabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver BioreactorUjjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. TannenbaumDrug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495
Tao, Wenli
- You have accessPharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal ImpairmentRobin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. WilkisonDrug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828
Thomas, Holly R.
- You have accessActivity Suppression Behavior Phenotype in SULT4A1 Frameshift Mutant ZebrafishFrank Crittenden, Holly R. Thomas, John M. Parant and Charles N. FalanyDrug Metabolism and Disposition July 2015, 43 (7) 1037-1044; DOI: https://doi.org/10.1124/dmd.115.064485
Tian, Dan-Dan
- You have accessPeony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro ModelsWei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin ZhangDrug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653
Tiller, Philip
- You have accessStructural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. WatersDrug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014
Tsai, Keng-Chang
- You have accessThe Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated InhibitionSheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang UengDrug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966
Tsuneyama, Koichi
- You have accessCarbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in RatsAzumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370
Tu, Mei-Juan
- You have accessChimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve ChemosensitivityMei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming YuDrug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493
Tukey, Robert H.
- You have accessExpression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse BrainYuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi FujiwaraDrug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719
Tung, Aveline
- You have accessRelative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult MiceShuang Wang, Debbie Bott, Aveline Tung, Kim S. Sugamori and Denis M. GrantDrug Metabolism and Disposition July 2015, 43 (7) 916-921; DOI: https://doi.org/10.1124/dmd.115.063297
U
Uehara, Shotaro
- You have accessSubstrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 969-976; DOI: https://doi.org/10.1124/dmd.115.063909
- You have accessComprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz OxidaseShinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925
Ueng, Yune-Fang
- You have accessThe Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated InhibitionSheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang UengDrug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966
Unadkat, Jashvant D.
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Uno, Yasuhiro
- You have accessSubstrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 969-976; DOI: https://doi.org/10.1124/dmd.115.063909
- You have accessComprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz OxidaseShinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925
Ushikubo, Hiroko
- You have accessExpression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse BrainYuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi FujiwaraDrug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719
V
Varma, Manthena V. S.
- You have accessQuantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-GlucuronideManthena V. S. Varma, Jian Lin, Yi-an Bi, Emi Kimoto and A. David RodriguesDrug Metabolism and Disposition July 2015, 43 (7) 1108-1118; DOI: https://doi.org/10.1124/dmd.115.064303
W
Walczak, Maria
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Walker, Susan
- You have accessPharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal ImpairmentRobin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. WilkisonDrug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828
Wandzel, Krystyna
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Wang, Chuan-Yue
- You have accessPeony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro ModelsWei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin ZhangDrug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653
Wang, Di
- You have accessPeony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro ModelsWei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin ZhangDrug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653
Wang, Fei
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Wang, Michael Zhuo
- You have accessEthnic Variability in the Expression of Hepatic Drug Transporters: Absolute Quantification by an Optimized Targeted Quantitative Proteomic ApproachKuan-wei Peng, James Bacon, Ming Zheng, Yingying Guo and Michael Zhuo WangDrug Metabolism and Disposition July 2015, 43 (7) 1045-1055; DOI: https://doi.org/10.1124/dmd.115.063362
Wang, Shuang
- You have accessRelative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult MiceShuang Wang, Debbie Bott, Aveline Tung, Kim S. Sugamori and Denis M. GrantDrug Metabolism and Disposition July 2015, 43 (7) 916-921; DOI: https://doi.org/10.1124/dmd.115.063297
Wang, Wei
- You have accessPeony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro ModelsWei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin ZhangDrug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653
Wang, Wei-Peng
- You have accessChimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve ChemosensitivityMei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming YuDrug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493
Wang, Xi-Tao
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Wang, Ying
- You have accessUDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver MicrosomesLijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
Wang-Smith, Laurene
- You have accessPharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal ImpairmentRobin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. WilkisonDrug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828
Waters, Nigel J.
- You have accessStructural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. WatersDrug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014
Wilkison, William O.
- You have accessPharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal ImpairmentRobin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. WilkisonDrug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828
Wishnok, John S.
- You have accessMetabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver BioreactorUjjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. TannenbaumDrug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495
Wu, Peng
- You have accessUDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver MicrosomesLijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
Wu, Tian-Shung
- You have accessThe Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated InhibitionSheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang UengDrug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966
X
Xu, Han
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Y
Yamazaki, Hiroshi
- You have accessSubstrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 969-976; DOI: https://doi.org/10.1124/dmd.115.063909
- You have accessComprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz OxidaseShinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi YamazakiDrug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925
Yang, Qi Joy
- You have accessResponse to Letter to the Editor on “Fractional Clearance for Verapamil N-Demethylation in the Isolated Rat Liver Preparation”K. Sandy Pang and Qi Joy YangDrug Metabolism and Disposition July 2015, 43 (7) 1058-1059; DOI: https://doi.org/10.1124/dmd.115.065227
Yano, Azusa
- You have accessCarbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in RatsAzumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370
Ye, June
- You have accessPharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal ImpairmentRobin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. WilkisonDrug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828
Yokoi, Tsuyoshi
- You have accessCarbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in RatsAzumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi YokoiDrug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370
Yu, Ai-Ming
- You have accessChimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve ChemosensitivityMei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming YuDrug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493
Yu, Na
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Z
Zabielski, Piotr
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Zakrzewska, Agnieszka
- You have accessHepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and PharmacokineticsKamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan ChlopickiDrug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388
Zeng, Shan
- You have accessUDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver MicrosomesLijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
Zeng, Su
- You have accessChimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve ChemosensitivityMei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming YuDrug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493
Zhang, Haoming
- You have accessHydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring PolymorphismsDiane M. Calinski, Haoming Zhang, Susan Ludeman, M. Eileen Dolan and Paul F. HollenbergDrug Metabolism and Disposition July 2015, 43 (7) 1084-1090; DOI: https://doi.org/10.1124/dmd.115.063628
Zhang, Xinyuan
- You have accessMetabolism of Bupropion by Carbonyl Reductases in Liver and IntestineJamie N. Connarn, Xinyuan Zhang, Andrew Babiskin and Duxin SunDrug Metabolism and Disposition July 2015, 43 (7) 1019-1027; DOI: https://doi.org/10.1124/dmd.115.063107
Zhang, Xuan
- You have accessSolute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug PenetrationHoufu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder SahiDrug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170
Zhang, Yueping
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Zhang, Zhang-Jin
- You have accessPeony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro ModelsWei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin ZhangDrug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653
Zhao, Yue
- You have accessCharacterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular ExpressionHong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong LaiDrug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364
Zheng, Bin
- You have accessPeony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro ModelsWei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin ZhangDrug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653
Zheng, Ming
- You have accessEthnic Variability in the Expression of Hepatic Drug Transporters: Absolute Quantification by an Optimized Targeted Quantitative Proteomic ApproachKuan-wei Peng, James Bacon, Ming Zheng, Yingying Guo and Michael Zhuo WangDrug Metabolism and Disposition July 2015, 43 (7) 1045-1055; DOI: https://doi.org/10.1124/dmd.115.063362
Zhu, Lijun
- You have accessUDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver MicrosomesLijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
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