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Index by author

July 01, 2015; Volume 43,Issue 7

A

  1. Addepalli, Balasubrahmanyam

    1. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity
      Mei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493

  2. An, Gang

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

B

  1. Babiskin, Andrew

    1. Metabolism of Bupropion by Carbonyl Reductases in Liver and Intestine
      Jamie N. Connarn, Xinyuan Zhang, Andrew Babiskin and Duxin Sun
      Drug Metabolism and Disposition July 2015, 43 (7) 1019-1027; DOI: https://doi.org/10.1124/dmd.115.063107

  2. Bacon, James

    1. Ethnic Variability in the Expression of Hepatic Drug Transporters: Absolute Quantification by an Optimized Targeted Quantitative Proteomic Approach
      Kuan-wei Peng, James Bacon, Ming Zheng, Yingying Guo and Michael Zhuo Wang
      Drug Metabolism and Disposition July 2015, 43 (7) 1045-1055; DOI: https://doi.org/10.1124/dmd.115.063362

  3. Barrett, Kathleen G.

    1. Upregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation
      Kathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-Morris
      Drug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440

  4. Bi, Yi-an

    1. Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide
      Manthena V. S. Varma, Jian Lin, Yi-an Bi, Emi Kimoto and A. David Rodrigues
      Drug Metabolism and Disposition July 2015, 43 (7) 1108-1118; DOI: https://doi.org/10.1124/dmd.115.064303

  5. Blanco, Javier G.

    1. Characterization of the Canine Anthracycline-Metabolizing Enzyme Carbonyl Reductase 1 (cbr1) and the Functional Isoform cbr1 V218
      Daniel C. Ferguson, Qiuying Cheng and Javier G. Blanco
      Drug Metabolism and Disposition July 2015, 43 (7) 922-927; DOI: https://doi.org/10.1124/dmd.115.064295

  6. Bott, Debbie

    1. Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice
      Shuang Wang, Debbie Bott, Aveline Tung, Kim S. Sugamori and Denis M. Grant
      Drug Metabolism and Disposition July 2015, 43 (7) 916-921; DOI: https://doi.org/10.1124/dmd.115.063297

C

  1. Calinski, Diane M.

    1. Hydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring Polymorphisms
      Diane M. Calinski, Haoming Zhang, Susan Ludeman, M. Eileen Dolan and Paul F. Hollenberg
      Drug Metabolism and Disposition July 2015, 43 (7) 1084-1090; DOI: https://doi.org/10.1124/dmd.115.063628

  2. Chabowski, Adrian

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  3. Chang, Chia-Yu

    1. The Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated Inhibition
      Sheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang Ueng
      Drug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966

  4. Cheatham, Bentley

    1. Pharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal Impairment
      Robin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. Wilkison
      Drug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828

  5. Chen, Cliff

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  6. Chen, Qiu-Xia

    1. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity
      Mei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493

  7. Cheng, Qiuying

    1. Characterization of the Canine Anthracycline-Metabolizing Enzyme Carbonyl Reductase 1 (cbr1) and the Functional Isoform cbr1 V218
      Daniel C. Ferguson, Qiuying Cheng and Javier G. Blanco
      Drug Metabolism and Disposition July 2015, 43 (7) 922-927; DOI: https://doi.org/10.1124/dmd.115.064295

  8. Chesworth, Richard

    1. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652
      Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. Waters
      Drug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014

  9. Chlopicki, Stefan

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  10. Christopher, Lisa J.

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  11. Connarn, Jamie N.

    1. Metabolism of Bupropion by Carbonyl Reductases in Liver and Intestine
      Jamie N. Connarn, Xinyuan Zhang, Andrew Babiskin and Duxin Sun
      Drug Metabolism and Disposition July 2015, 43 (7) 1019-1027; DOI: https://doi.org/10.1124/dmd.115.063107

  12. Copeland, Robert A.

    1. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652
      Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. Waters
      Drug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014

  13. Crittenden, Frank

    1. Activity Suppression Behavior Phenotype in SULT4A1 Frameshift Mutant Zebrafish
      Frank Crittenden, Holly R. Thomas, John M. Parant and Charles N. Falany
      Drug Metabolism and Disposition July 2015, 43 (7) 1037-1044; DOI: https://doi.org/10.1124/dmd.115.064485

  14. Csanaky, Iván L.

    1. Multidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of Diclofenac
      Renato J. Scialis, Iván L. Csanaky, Michael J. Goedken and José E. Manautou
      Drug Metabolism and Disposition July 2015, 43 (7) 944-950; DOI: https://doi.org/10.1124/dmd.114.061705

  15. Cukovic, Daniela

    1. Upregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation
      Kathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-Morris
      Drug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440

D

  1. Dai, Peimin

    1. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes
      Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552

  2. Deshmukh, Gauri

    1. Use of Cassette Dosing to Enhance the Throughput of Rat Brain Microdialysis Studies
      Gauri Deshmukh, Kefeng Sun, Bianca M. Liederer, Xiao Ding and Xingrong Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 1123-1128; DOI: https://doi.org/10.1124/dmd.115.064204

  3. Ding, Xiao

    1. Use of Cassette Dosing to Enhance the Throughput of Rat Brain Microdialysis Studies
      Gauri Deshmukh, Kefeng Sun, Bianca M. Liederer, Xiao Ding and Xingrong Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 1123-1128; DOI: https://doi.org/10.1124/dmd.115.064204

  4. Dobbins, Robert L.

    1. Pharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal Impairment
      Robin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. Wilkison
      Drug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828

  5. Dolan, M. Eileen

    1. Hydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring Polymorphisms
      Diane M. Calinski, Haoming Zhang, Susan Ludeman, M. Eileen Dolan and Paul F. Hollenberg
      Drug Metabolism and Disposition July 2015, 43 (7) 1084-1090; DOI: https://doi.org/10.1124/dmd.115.063628

  6. Dombkowski, Alan A.

    1. Upregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation
      Kathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-Morris
      Drug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440

  7. Dyer, Rachel L.

    1. Metabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver Bioreactor
      Ujjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. Tannenbaum
      Drug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495

E

  1. Ebrahimkhani, Mohammad R.

    1. Metabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver Bioreactor
      Ujjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. Tannenbaum
      Drug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495

F

  1. Falany, Charles N.

    1. Activity Suppression Behavior Phenotype in SULT4A1 Frameshift Mutant Zebrafish
      Frank Crittenden, Holly R. Thomas, John M. Parant and Charles N. Falany
      Drug Metabolism and Disposition July 2015, 43 (7) 1037-1044; DOI: https://doi.org/10.1124/dmd.115.064485

  2. Fang, Hailin

    1. Upregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation
      Kathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-Morris
      Drug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440

  3. Ferguson, Daniel C.

    1. Characterization of the Canine Anthracycline-Metabolizing Enzyme Carbonyl Reductase 1 (cbr1) and the Functional Isoform cbr1 V218
      Daniel C. Ferguson, Qiuying Cheng and Javier G. Blanco
      Drug Metabolism and Disposition July 2015, 43 (7) 922-927; DOI: https://doi.org/10.1124/dmd.115.064295

  4. Friedel, Christina

    1. Differences in Methadone Metabolism by CYP2B6 Variants
      Sarah Gadel, Christina Friedel and Evan D. Kharasch
      Drug Metabolism and Disposition July 2015, 43 (7) 994-1001; DOI: https://doi.org/10.1124/dmd.115.064352

  5. Frost, Kerry

    1. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652
      Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. Waters
      Drug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014

  6. Fujiwara, Ryoichi

    1. Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain
      Yuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719

  7. Fukami, Tatsuki

    1. Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats
      Azumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370

G

  1. Gadel, Sarah

    1. Differences in Methadone Metabolism by CYP2B6 Variants
      Sarah Gadel, Christina Friedel and Evan D. Kharasch
      Drug Metabolism and Disposition July 2015, 43 (7) 994-1001; DOI: https://doi.org/10.1124/dmd.115.064352

  2. Goedken, Michael J.

    1. Multidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of Diclofenac
      Renato J. Scialis, Iván L. Csanaky, Michael J. Goedken and José E. Manautou
      Drug Metabolism and Disposition July 2015, 43 (7) 944-950; DOI: https://doi.org/10.1124/dmd.114.061705

  3. Gonciarz-Dytman, Anna

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  4. Grant, Denis M.

    1. Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice
      Shuang Wang, Debbie Bott, Aveline Tung, Kim S. Sugamori and Denis M. Grant
      Drug Metabolism and Disposition July 2015, 43 (7) 916-921; DOI: https://doi.org/10.1124/dmd.115.063297

  5. Griffith, Linda G.

    1. Metabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver Bioreactor
      Ujjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. Tannenbaum
      Drug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495

  6. Guo, Yingying

    1. Ethnic Variability in the Expression of Hepatic Drug Transporters: Absolute Quantification by an Optimized Targeted Quantitative Proteomic Approach
      Kuan-wei Peng, James Bacon, Ming Zheng, Yingying Guo and Michael Zhuo Wang
      Drug Metabolism and Disposition July 2015, 43 (7) 1045-1055; DOI: https://doi.org/10.1124/dmd.115.063362

H

  1. He, Enuo

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  2. Hirashima, Rika

    1. Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain
      Yuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719

  3. Holland, Ryan J.

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  4. Hollenberg, Paul F.

    1. Hydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring Polymorphisms
      Diane M. Calinski, Haoming Zhang, Susan Ludeman, M. Eileen Dolan and Paul F. Hollenberg
      Drug Metabolism and Disposition July 2015, 43 (7) 1084-1090; DOI: https://doi.org/10.1124/dmd.115.063628

  5. Hosaka, Shinya

    1. Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925

  6. House, Larry K.

    1. Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10
      Jacqueline Ramírez, Snezana Mirkov, Larry K. House and Mark J. Ratain
      Drug Metabolism and Disposition July 2015, 43 (7) 928-935; DOI: https://doi.org/10.1124/dmd.115.063271

  7. Hu, Ming

    1. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes
      Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552

  8. Huang, Chiung-Chiao

    1. The Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated Inhibition
      Sheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang Ueng
      Drug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966

  9. Huang, Min

    1. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity
      Mei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493

  10. Hughes, David J.

    1. Metabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver Bioreactor
      Ujjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. Tannenbaum
      Drug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495

  11. Hussey, Elizabeth K.

    1. Pharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal Impairment
      Robin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. Wilkison
      Drug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828

I

  1. Iida, Azumi

    1. Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats
      Azumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370

  2. Inoue, Takashi

    1. Substrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 969-976; DOI: https://doi.org/10.1124/dmd.115.063909

  3. Ito, Sumito

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  4. Itoh, Tomoo

    1. Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain
      Yuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719

  5. Iwano, Shunsuke

    1. Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925

  6. Iwasaki, Kazuhide

    1. Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925

J

  1. Jeong, Hyunyoung

    1. Farnesoid X Receptor Agonist Represses Cytochrome P450 2D6 Expression by Upregulating Small Heterodimer Partner
      Xian Pan, Yoon-Kwang Lee and Hyunyoung Jeong
      Drug Metabolism and Disposition July 2015, 43 (7) 1002-1007; DOI: https://doi.org/10.1124/dmd.115.064758

  2. Ji, Hyeon-Kyeong

    1. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5′-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography–Tandem Mass Spectrometry
      Boram Lee, Hyeon-Kyeong Ji, Taeho Lee and Kwang-Hyeon Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 1137-1146; DOI: https://doi.org/10.1124/dmd.114.063016

K

  1. Kapur, Anita

    1. Pharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal Impairment
      Robin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. Wilkison
      Drug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828

  2. Keefer, Larry K.

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  3. Kharasch, Evan D.

    1. Differences in Methadone Metabolism by CYP2B6 Variants
      Sarah Gadel, Christina Friedel and Evan D. Kharasch
      Drug Metabolism and Disposition July 2015, 43 (7) 994-1001; DOI: https://doi.org/10.1124/dmd.115.064352

  4. Kij, Agnieszka

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  5. Kimoto, Emi

    1. Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide
      Manthena V. S. Varma, Jian Lin, Yi-an Bi, Emi Kimoto and A. David Rodrigues
      Drug Metabolism and Disposition July 2015, 43 (7) 1108-1118; DOI: https://doi.org/10.1124/dmd.115.064303

  6. Kocarek, Thomas A.

    1. Upregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation
      Kathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-Morris
      Drug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440

  7. Kus, Kamil

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  8. Kusuhara, Hiroyuki

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  9. Kutsuno, Yuki

    1. Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain
      Yuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719

L

  1. Lai, Yurong

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  2. Large, Emma M.

    1. Metabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver Bioreactor
      Ujjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. Tannenbaum
      Drug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495

  3. LaSalle, Janine M.

    1. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity
      Mei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493

  4. Lee, Boram

    1. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5′-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography–Tandem Mass Spectrometry
      Boram Lee, Hyeon-Kyeong Ji, Taeho Lee and Kwang-Hyeon Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 1137-1146; DOI: https://doi.org/10.1124/dmd.114.063016

  5. Lee, Taeho

    1. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5′-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography–Tandem Mass Spectrometry
      Boram Lee, Hyeon-Kyeong Ji, Taeho Lee and Kwang-Hyeon Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 1137-1146; DOI: https://doi.org/10.1124/dmd.114.063016

  6. Lee, Yoon-Kwang

    1. Farnesoid X Receptor Agonist Represses Cytochrome P450 2D6 Expression by Upregulating Small Heterodimer Partner
      Xian Pan, Yoon-Kwang Lee and Hyunyoung Jeong
      Drug Metabolism and Disposition July 2015, 43 (7) 1002-1007; DOI: https://doi.org/10.1124/dmd.115.064758

  7. Lewin, Anne C.

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  8. Li, Mei-Mei

    1. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity
      Mei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493

  9. Li, Yang

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  10. Liederer, Bianca M.

    1. Use of Cassette Dosing to Enhance the Throughput of Rat Brain Microdialysis Studies
      Gauri Deshmukh, Kefeng Sun, Bianca M. Liederer, Xiao Ding and Xingrong Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 1123-1128; DOI: https://doi.org/10.1124/dmd.115.064204

  11. Limbach, Patrick A.

    1. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity
      Mei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493

  12. Lin, Jian

    1. Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide
      Manthena V. S. Varma, Jian Lin, Yi-an Bi, Emi Kimoto and A. David Rodrigues
      Drug Metabolism and Disposition July 2015, 43 (7) 1108-1118; DOI: https://doi.org/10.1124/dmd.115.064303

  13. Liu, Guowen

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  14. Liu, Houfu

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  15. Liu, Kwang-Hyeon

    1. Simultaneous Screening of Activities of Five Cytochrome P450 and Four Uridine 5′-Diphospho-glucuronosyltransferase Enzymes in Human Liver Microsomes Using Cocktail Incubation and Liquid Chromatography–Tandem Mass Spectrometry
      Boram Lee, Hyeon-Kyeong Ji, Taeho Lee and Kwang-Hyeon Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 1137-1146; DOI: https://doi.org/10.1124/dmd.114.063016

  16. Liu, Liang

    1. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes
      Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552

  17. Liu, Tongtong

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  18. Liu, Xingrong

    1. Use of Cassette Dosing to Enhance the Throughput of Rat Brain Microdialysis Studies
      Gauri Deshmukh, Kefeng Sun, Bianca M. Liederer, Xiao Ding and Xingrong Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 1123-1128; DOI: https://doi.org/10.1124/dmd.115.064204

  19. Liu, Zhongqiu

    1. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes
      Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552

  20. Lo, Sheng-Nan

    1. The Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated Inhibition
      Sheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang Ueng
      Drug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966

  21. Lu, Linlin

    1. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes
      Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552

  22. Lu, Sijie

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  23. Lu, Xinyan

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  24. Ludeman, Susan

    1. Hydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring Polymorphisms
      Diane M. Calinski, Haoming Zhang, Susan Ludeman, M. Eileen Dolan and Paul F. Hollenberg
      Drug Metabolism and Disposition July 2015, 43 (7) 1084-1090; DOI: https://doi.org/10.1124/dmd.115.063628

  25. Luo, Feifei

    1. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes
      Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552

M

  1. Manautou, José E.

    1. Multidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of Diclofenac
      Renato J. Scialis, Iván L. Csanaky, Michael J. Goedken and José E. Manautou
      Drug Metabolism and Disposition July 2015, 43 (7) 944-950; DOI: https://doi.org/10.1124/dmd.114.061705

  2. Marathe, Punit

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  3. Maslak, Edyta

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  4. Mehvar, Reza

    1. Fractional Clearance for Verapamil N-Demethylation in the Isolated Rat Liver Preparation
      Reza Mehvar
      Drug Metabolism and Disposition July 2015, 43 (7) 1056-1057; DOI: https://doi.org/10.1124/dmd.115.064691

  5. Michimae, Hirofumi

    1. Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain
      Yuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719

  6. Mirkov, Snezana

    1. Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10
      Jacqueline Ramírez, Snezana Mirkov, Larry K. House and Mark J. Ratain
      Drug Metabolism and Disposition July 2015, 43 (7) 928-935; DOI: https://doi.org/10.1124/dmd.115.063271

  7. Mitchell, Lorna H.

    1. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652
      Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. Waters
      Drug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014

  8. Morse, Bridget L.

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  9. Moyer, Mikel P.

    1. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652
      Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. Waters
      Drug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014

  10. Murayama, Norie

    1. Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925

N

  1. Nakajima, Miki

    1. Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats
      Azumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370

O

  1. O’Connor-Semmes, Robin

    1. Pharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal Impairment
      Robin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. Wilkison
      Drug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828

P

  1. Pan, Xian

    1. Farnesoid X Receptor Agonist Represses Cytochrome P450 2D6 Expression by Upregulating Small Heterodimer Partner
      Xian Pan, Yoon-Kwang Lee and Hyunyoung Jeong
      Drug Metabolism and Disposition July 2015, 43 (7) 1002-1007; DOI: https://doi.org/10.1124/dmd.115.064758

  2. Pang, K. Sandy

    1. Response to Letter to the Editor on “Fractional Clearance for Verapamil N-Demethylation in the Isolated Rat Liver Preparation”
      K. Sandy Pang and Qi Joy Yang
      Drug Metabolism and Disposition July 2015, 43 (7) 1058-1059; DOI: https://doi.org/10.1124/dmd.115.065227

  3. Parant, John M.

    1. Activity Suppression Behavior Phenotype in SULT4A1 Frameshift Mutant Zebrafish
      Frank Crittenden, Holly R. Thomas, John M. Parant and Charles N. Falany
      Drug Metabolism and Disposition July 2015, 43 (7) 1037-1044; DOI: https://doi.org/10.1124/dmd.115.064485

  4. Peng, Kuan-wei

    1. Ethnic Variability in the Expression of Hepatic Drug Transporters: Absolute Quantification by an Optimized Targeted Quantitative Proteomic Approach
      Kuan-wei Peng, James Bacon, Ming Zheng, Yingying Guo and Michael Zhuo Wang
      Drug Metabolism and Disposition July 2015, 43 (7) 1045-1055; DOI: https://doi.org/10.1124/dmd.115.063362

  5. Petrovic, Vanja

    1. Polyinosinic/Polycytidylic Acid–Mediated Changes in Maternal and Fetal Disposition of Lopinavir in Rats
      Vanja Petrovic and Micheline Piquette-Miller
      Drug Metabolism and Disposition July 2015, 43 (7) 951-957; DOI: https://doi.org/10.1124/dmd.114.062315

  6. Piquette-Miller, Micheline

    1. Polyinosinic/Polycytidylic Acid–Mediated Changes in Maternal and Fetal Disposition of Lopinavir in Rats
      Vanja Petrovic and Micheline Piquette-Miller
      Drug Metabolism and Disposition July 2015, 43 (7) 951-957; DOI: https://doi.org/10.1124/dmd.114.062315

  7. Plant, Katie

    1. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652
      Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. Waters
      Drug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014

  8. Prasad, Bhagwat

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

Q

  1. Qiu, Xi

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

R

  1. Ramírez, Jacqueline

    1. Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10
      Jacqueline Ramírez, Snezana Mirkov, Larry K. House and Mark J. Ratain
      Drug Metabolism and Disposition July 2015, 43 (7) 928-935; DOI: https://doi.org/10.1124/dmd.115.063271

  2. Ratain, Mark J.

    1. Glucuronidation of OTS167 in Humans Is Catalyzed by UDP-Glucuronosyltransferases UGT1A1, UGT1A3, UGT1A8, and UGT1A10
      Jacqueline Ramírez, Snezana Mirkov, Larry K. House and Mark J. Ratain
      Drug Metabolism and Disposition July 2015, 43 (7) 928-935; DOI: https://doi.org/10.1124/dmd.115.063271

  3. Ravindra, Kodihalli C.

    1. Metabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver Bioreactor
      Ujjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. Tannenbaum
      Drug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495

  4. Ribich, Scott

    1. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652
      Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. Waters
      Drug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014

  5. Rioux, Nathalie

    1. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652
      Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. Waters
      Drug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014

  6. Rivera-Burgos, Dinelia

    1. Metabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver Bioreactor
      Ujjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. Tannenbaum
      Drug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495

  7. Rodrigues, A. David

    1. Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide
      Manthena V. S. Varma, Jian Lin, Yi-an Bi, Emi Kimoto and A. David Rodrigues
      Drug Metabolism and Disposition July 2015, 43 (7) 1108-1118; DOI: https://doi.org/10.1124/dmd.115.064303

  8. Runge-Morris, Melissa

    1. Upregulation of UGT2B4 Expression by 3′-Phosphoadenosine-5′-Phosphosulfate Synthase Knockdown: Implications for Coordinated Control of Bile Acid Conjugation
      Kathleen G. Barrett, Hailin Fang, Daniela Cukovic, Alan A. Dombkowski, Thomas A. Kocarek and Melissa Runge-Morris
      Drug Metabolism and Disposition July 2015, 43 (7) 1061-1070; DOI: https://doi.org/10.1124/dmd.114.061440

S

  1. Saavedra, Joseph E.

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  2. Sahi, Jasminder

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  3. Sakamoto, Masaya

    1. Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain
      Yuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719

  4. Sarkar, Ujjal

    1. Metabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver Bioreactor
      Ujjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. Tannenbaum
      Drug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495

  5. Sasaki, Eita

    1. Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats
      Azumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370

  6. Sasaki, Erika

    1. Substrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 969-976; DOI: https://doi.org/10.1124/dmd.115.063909

  7. Satsukawa, Masahiro

    1. Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925

  8. Scialis, Renato J.

    1. Multidrug Resistance-Associated Protein 3 Plays an Important Role in Protection against Acute Toxicity of Diclofenac
      Renato J. Scialis, Iván L. Csanaky, Michael J. Goedken and José E. Manautou
      Drug Metabolism and Disposition July 2015, 43 (7) 944-950; DOI: https://doi.org/10.1124/dmd.114.061705

  9. Shaw, Joanne

    1. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652
      Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. Waters
      Drug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014

  10. Shen, Chien-Chang

    1. The Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated Inhibition
      Sheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang Ueng
      Drug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966

  11. Shen, Hong

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  12. Shimizu, Makiko

    1. Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925

  13. Sitek, Barbara

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  14. Sugamori, Kim S.

    1. Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice
      Shuang Wang, Debbie Bott, Aveline Tung, Kim S. Sugamori and Denis M. Grant
      Drug Metabolism and Disposition July 2015, 43 (7) 916-921; DOI: https://doi.org/10.1124/dmd.115.063297

  15. Sugiyama, Yuichi

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  16. Sun, Duxin

    1. Metabolism of Bupropion by Carbonyl Reductases in Liver and Intestine
      Jamie N. Connarn, Xinyuan Zhang, Andrew Babiskin and Duxin Sun
      Drug Metabolism and Disposition July 2015, 43 (7) 1019-1027; DOI: https://doi.org/10.1124/dmd.115.063107

  17. Sun, Kefeng

    1. Use of Cassette Dosing to Enhance the Throughput of Rat Brain Microdialysis Studies
      Gauri Deshmukh, Kefeng Sun, Bianca M. Liederer, Xiao Ding and Xingrong Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 1123-1128; DOI: https://doi.org/10.1124/dmd.115.064204

T

  1. Tan, Qing-Rong

    1. Peony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro Models
      Wei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin Zhang
      Drug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653

  2. Tannenbaum, Steven R.

    1. Metabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver Bioreactor
      Ujjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. Tannenbaum
      Drug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495

  3. Tao, Wenli

    1. Pharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal Impairment
      Robin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. Wilkison
      Drug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828

  4. Thomas, Holly R.

    1. Activity Suppression Behavior Phenotype in SULT4A1 Frameshift Mutant Zebrafish
      Frank Crittenden, Holly R. Thomas, John M. Parant and Charles N. Falany
      Drug Metabolism and Disposition July 2015, 43 (7) 1037-1044; DOI: https://doi.org/10.1124/dmd.115.064485

  5. Tian, Dan-Dan

    1. Peony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro Models
      Wei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin Zhang
      Drug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653

  6. Tiller, Philip

    1. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652
      Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. Waters
      Drug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014

  7. Tsai, Keng-Chang

    1. The Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated Inhibition
      Sheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang Ueng
      Drug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966

  8. Tsuneyama, Koichi

    1. Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats
      Azumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370

  9. Tu, Mei-Juan

    1. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity
      Mei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493

  10. Tukey, Robert H.

    1. Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain
      Yuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719

  11. Tung, Aveline

    1. Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice
      Shuang Wang, Debbie Bott, Aveline Tung, Kim S. Sugamori and Denis M. Grant
      Drug Metabolism and Disposition July 2015, 43 (7) 916-921; DOI: https://doi.org/10.1124/dmd.115.063297

U

  1. Uehara, Shotaro

    1. Substrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 969-976; DOI: https://doi.org/10.1124/dmd.115.063909
    2. Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925

  2. Ueng, Yune-Fang

    1. The Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated Inhibition
      Sheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang Ueng
      Drug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966

  3. Unadkat, Jashvant D.

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  4. Uno, Yasuhiro

    1. Substrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 969-976; DOI: https://doi.org/10.1124/dmd.115.063909
    2. Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925

  5. Ushikubo, Hiroko

    1. Expression of UDP-Glucuronosyltransferase 1 (UGT1) and Glucuronidation Activity toward Endogenous Substances in Humanized UGT1 Mouse Brain
      Yuki Kutsuno, Rika Hirashima, Masaya Sakamoto, Hiroko Ushikubo, Hirofumi Michimae, Tomoo Itoh, Robert H. Tukey and Ryoichi Fujiwara
      Drug Metabolism and Disposition July 2015, 43 (7) 1071-1076; DOI: https://doi.org/10.1124/dmd.115.063719

V

  1. Varma, Manthena V. S.

    1. Quantitative Rationalization of Gemfibrozil Drug Interactions: Consideration of Transporters-Enzyme Interplay and the Role of Circulating Metabolite Gemfibrozil 1-O-β-Glucuronide
      Manthena V. S. Varma, Jian Lin, Yi-an Bi, Emi Kimoto and A. David Rodrigues
      Drug Metabolism and Disposition July 2015, 43 (7) 1108-1118; DOI: https://doi.org/10.1124/dmd.115.064303

W

  1. Walczak, Maria

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  2. Walker, Susan

    1. Pharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal Impairment
      Robin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. Wilkison
      Drug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828

  3. Wandzel, Krystyna

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  4. Wang, Chuan-Yue

    1. Peony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro Models
      Wei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin Zhang
      Drug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653

  5. Wang, Di

    1. Peony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro Models
      Wei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin Zhang
      Drug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653

  6. Wang, Fei

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  7. Wang, Michael Zhuo

    1. Ethnic Variability in the Expression of Hepatic Drug Transporters: Absolute Quantification by an Optimized Targeted Quantitative Proteomic Approach
      Kuan-wei Peng, James Bacon, Ming Zheng, Yingying Guo and Michael Zhuo Wang
      Drug Metabolism and Disposition July 2015, 43 (7) 1045-1055; DOI: https://doi.org/10.1124/dmd.115.063362

  8. Wang, Shuang

    1. Relative Contributions of CYP1A2 and CYP2E1 to the Bioactivation and Clearance of 4-Aminobiphenyl in Adult Mice
      Shuang Wang, Debbie Bott, Aveline Tung, Kim S. Sugamori and Denis M. Grant
      Drug Metabolism and Disposition July 2015, 43 (7) 916-921; DOI: https://doi.org/10.1124/dmd.115.063297

  9. Wang, Wei

    1. Peony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro Models
      Wei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin Zhang
      Drug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653

  10. Wang, Wei-Peng

    1. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity
      Mei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493

  11. Wang, Xi-Tao

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  12. Wang, Ying

    1. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes
      Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552

  13. Wang-Smith, Laurene

    1. Pharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal Impairment
      Robin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. Wilkison
      Drug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828

  14. Waters, Nigel J.

    1. Structural and Kinetic Characterization of a Novel N-acetylated Aliphatic Amine Metabolite of the PRMT Inhibitor, EPZ011652
      Nathalie Rioux, Lorna H. Mitchell, Philip Tiller, Katie Plant, Joanne Shaw, Kerry Frost, Scott Ribich, Mikel P. Moyer, Robert A. Copeland, Richard Chesworth and Nigel J. Waters
      Drug Metabolism and Disposition July 2015, 43 (7) 936-943; DOI: https://doi.org/10.1124/dmd.115.064014

  15. Wilkison, William O.

    1. Pharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal Impairment
      Robin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. Wilkison
      Drug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828

  16. Wishnok, John S.

    1. Metabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver Bioreactor
      Ujjal Sarkar, Dinelia Rivera-Burgos, Emma M. Large, David J. Hughes, Kodihalli C. Ravindra, Rachel L. Dyer, Mohammad R. Ebrahimkhani, John S. Wishnok, Linda G. Griffith and Steven R. Tannenbaum
      Drug Metabolism and Disposition July 2015, 43 (7) 1091-1099; DOI: https://doi.org/10.1124/dmd.115.063495

  17. Wu, Peng

    1. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes
      Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552

  18. Wu, Tian-Shung

    1. The Effect of Oxidation on Berberine-Mediated CYP1 Inhibition: Oxidation Behavior and Metabolite-Mediated Inhibition
      Sheng-Nan Lo, Chien-Chang Shen, Chia-Yu Chang, Keng-Chang Tsai, Chiung-Chiao Huang, Tian-Shung Wu and Yune-Fang Ueng
      Drug Metabolism and Disposition July 2015, 43 (7) 1100-1107; DOI: https://doi.org/10.1124/dmd.115.063966

X

  1. Xu, Han

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

Y

  1. Yamazaki, Hiroshi

    1. Substrate Selectivities and Catalytic Activities of Marmoset Liver Cytochrome P450 2A6 Differed from Those of Human P450 2A6
      Shotaro Uehara, Yasuhiro Uno, Takashi Inoue, Erika Sasaki and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 969-976; DOI: https://doi.org/10.1124/dmd.115.063909
    2. Comprehensive Evaluation for Substrate Selectivity of Cynomolgus Monkey Cytochrome P450 2C9, a New Efavirenz Oxidase
      Shinya Hosaka, Norie Murayama, Masahiro Satsukawa, Shotaro Uehara, Makiko Shimizu, Kazuhide Iwasaki, Shunsuke Iwano, Yasuhiro Uno and Hiroshi Yamazaki
      Drug Metabolism and Disposition July 2015, 43 (7) 1119-1122; DOI: https://doi.org/10.1124/dmd.115.063925

  2. Yang, Qi Joy

    1. Response to Letter to the Editor on “Fractional Clearance for Verapamil N-Demethylation in the Isolated Rat Liver Preparation”
      K. Sandy Pang and Qi Joy Yang
      Drug Metabolism and Disposition July 2015, 43 (7) 1058-1059; DOI: https://doi.org/10.1124/dmd.115.065227

  3. Yano, Azusa

    1. Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats
      Azumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370

  4. Ye, June

    1. Pharmacokinetics and Pharmacodynamics of the SGLT2 Inhibitor Remogliflozin Etabonate in Subjects with Mild and Moderate Renal Impairment
      Robin O’Connor-Semmes, Susan Walker, Anita Kapur, Elizabeth K. Hussey, June Ye, Laurene Wang-Smith, Wenli Tao, Robert L. Dobbins, Bentley Cheatham and William O. Wilkison
      Drug Metabolism and Disposition July 2015, 43 (7) 1077-1083; DOI: https://doi.org/10.1124/dmd.114.062828

  5. Yokoi, Tsuyoshi

    1. Carbamazepine-Induced Liver Injury Requires CYP3A-Mediated Metabolism and Glutathione Depletion in Rats
      Azumi Iida, Eita Sasaki, Azusa Yano, Koichi Tsuneyama, Tatsuki Fukami, Miki Nakajima and Tsuyoshi Yokoi
      Drug Metabolism and Disposition July 2015, 43 (7) 958-968; DOI: https://doi.org/10.1124/dmd.115.063370

  6. Yu, Ai-Ming

    1. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity
      Mei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493

  7. Yu, Na

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

Z

  1. Zabielski, Piotr

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  2. Zakrzewska, Agnieszka

    1. Hepatoselective Nitric Oxide (NO) Donors, V-PYRRO/NO and V-PROLI/NO, in Nonalcoholic Fatty Liver Disease: A Comparison of Antisteatotic Effects with the Biotransformation and Pharmacokinetics
      Kamil Kus, Maria Walczak, Edyta Maslak, Agnieszka Zakrzewska, Anna Gonciarz-Dytman, Piotr Zabielski, Barbara Sitek, Krystyna Wandzel, Agnieszka Kij, Adrian Chabowski, Ryan J. Holland, Joseph E. Saavedra, Larry K. Keefer and Stefan Chlopicki
      Drug Metabolism and Disposition July 2015, 43 (7) 1028-1036; DOI: https://doi.org/10.1124/dmd.115.063388

  3. Zeng, Shan

    1. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes
      Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552

  4. Zeng, Su

    1. Chimeric MicroRNA-1291 Biosynthesized Efficiently in Escherichia coli Is Effective to Reduce Target Gene Expression in Human Carcinoma Cells and Improve Chemosensitivity
      Mei-Mei Li, Balasubrahmanyam Addepalli, Mei-Juan Tu, Qiu-Xia Chen, Wei-Peng Wang, Patrick A. Limbach, Janine M. LaSalle, Su Zeng, Min Huang and Ai-Ming Yu
      Drug Metabolism and Disposition July 2015, 43 (7) 1129-1136; DOI: https://doi.org/10.1124/dmd.115.064493

  5. Zhang, Haoming

    1. Hydroxylation and N-Dechloroethylation of Ifosfamide and Deuterated Ifosfamide by the Human Cytochrome P450s and Their Commonly Occurring Polymorphisms
      Diane M. Calinski, Haoming Zhang, Susan Ludeman, M. Eileen Dolan and Paul F. Hollenberg
      Drug Metabolism and Disposition July 2015, 43 (7) 1084-1090; DOI: https://doi.org/10.1124/dmd.115.063628

  6. Zhang, Xinyuan

    1. Metabolism of Bupropion by Carbonyl Reductases in Liver and Intestine
      Jamie N. Connarn, Xinyuan Zhang, Andrew Babiskin and Duxin Sun
      Drug Metabolism and Disposition July 2015, 43 (7) 1019-1027; DOI: https://doi.org/10.1124/dmd.115.063107

  7. Zhang, Xuan

    1. Solute Carrier Family of the Organic Anion-Transporting Polypeptides 1A2– Madin-Darby Canine Kidney II: A Promising In Vitro System to Understand the Role of Organic Anion-Transporting Polypeptide 1A2 in Blood-Brain Barrier Drug Penetration
      Houfu Liu, Na Yu, Sijie Lu, Sumito Ito, Xuan Zhang, Bhagwat Prasad, Enuo He, Xinyan Lu, Yang Li, Fei Wang, Han Xu, Gang An, Jashvant D. Unadkat, Hiroyuki Kusuhara, Yuichi Sugiyama and Jasminder Sahi
      Drug Metabolism and Disposition July 2015, 43 (7) 1008-1018; DOI: https://doi.org/10.1124/dmd.115.064170

  8. Zhang, Yueping

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  9. Zhang, Zhang-Jin

    1. Peony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro Models
      Wei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin Zhang
      Drug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653

  10. Zhao, Yue

    1. Characterization of Organic Anion Transporter 2 (SLC22A7): A Highly Efficient Transporter for Creatinine and Species-Dependent Renal Tubular Expression
      Hong Shen, Tongtong Liu, Bridget L. Morse, Yue Zhao, Yueping Zhang, Xi Qiu, Cliff Chen, Anne C. Lewin, Xi-Tao Wang, Guowen Liu, Lisa J. Christopher, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition July 2015, 43 (7) 984-993; DOI: https://doi.org/10.1124/dmd.114.062364

  11. Zheng, Bin

    1. Peony-Glycyrrhiza Decoction, an Herbal Preparation, Inhibits Clozapine Metabolism via Cytochrome P450s, but Not Flavin-Containing Monooxygenase in In Vitro Models
      Wei Wang, Dan-Dan Tian, Bin Zheng, Di Wang, Qing-Rong Tan, Chuan-Yue Wang and Zhang-Jin Zhang
      Drug Metabolism and Disposition July 2015, 43 (7) 1147-1153; DOI: https://doi.org/10.1124/dmd.114.062653

  12. Zheng, Ming

    1. Ethnic Variability in the Expression of Hepatic Drug Transporters: Absolute Quantification by an Optimized Targeted Quantitative Proteomic Approach
      Kuan-wei Peng, James Bacon, Ming Zheng, Yingying Guo and Michael Zhuo Wang
      Drug Metabolism and Disposition July 2015, 43 (7) 1045-1055; DOI: https://doi.org/10.1124/dmd.115.063362

  13. Zhu, Lijun

    1. UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes
      Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
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