Research ArticleArticle
UDP-Glucuronosyltransferases 1A6 and 1A9 are the Major Isozymes Responsible for the 7-O-Glucuronidation of Esculetin and 4-Methylesculetin in Human Liver Microsomes
Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
Drug Metabolism and Disposition July 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
Lijun Zhu
International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China (Z.L.J., L.L.L., Z.S., L.F.F., D.P.M., W.P., W.Y., H.M., L.Z.Q.); Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas (H.M.); Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, PR China (D.P.M., W.Y.); and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau (SAR), PR China (L.L.)
Linlin Lu
International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China (Z.L.J., L.L.L., Z.S., L.F.F., D.P.M., W.P., W.Y., H.M., L.Z.Q.); Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas (H.M.); Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, PR China (D.P.M., W.Y.); and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau (SAR), PR China (L.L.)
Shan Zeng
International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China (Z.L.J., L.L.L., Z.S., L.F.F., D.P.M., W.P., W.Y., H.M., L.Z.Q.); Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas (H.M.); Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, PR China (D.P.M., W.Y.); and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau (SAR), PR China (L.L.)
Feifei Luo
International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China (Z.L.J., L.L.L., Z.S., L.F.F., D.P.M., W.P., W.Y., H.M., L.Z.Q.); Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas (H.M.); Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, PR China (D.P.M., W.Y.); and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau (SAR), PR China (L.L.)
Peimin Dai
International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China (Z.L.J., L.L.L., Z.S., L.F.F., D.P.M., W.P., W.Y., H.M., L.Z.Q.); Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas (H.M.); Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, PR China (D.P.M., W.Y.); and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau (SAR), PR China (L.L.)
Peng Wu
International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China (Z.L.J., L.L.L., Z.S., L.F.F., D.P.M., W.P., W.Y., H.M., L.Z.Q.); Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas (H.M.); Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, PR China (D.P.M., W.Y.); and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau (SAR), PR China (L.L.)
Ying Wang
International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China (Z.L.J., L.L.L., Z.S., L.F.F., D.P.M., W.P., W.Y., H.M., L.Z.Q.); Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas (H.M.); Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, PR China (D.P.M., W.Y.); and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau (SAR), PR China (L.L.)
Liang Liu
International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China (Z.L.J., L.L.L., Z.S., L.F.F., D.P.M., W.P., W.Y., H.M., L.Z.Q.); Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas (H.M.); Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, PR China (D.P.M., W.Y.); and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau (SAR), PR China (L.L.)
Ming Hu
International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China (Z.L.J., L.L.L., Z.S., L.F.F., D.P.M., W.P., W.Y., H.M., L.Z.Q.); Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas (H.M.); Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, PR China (D.P.M., W.Y.); and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau (SAR), PR China (L.L.)
Zhongqiu Liu
International Institute for Translational Chinese Medicine, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong, PR China (Z.L.J., L.L.L., Z.S., L.F.F., D.P.M., W.P., W.Y., H.M., L.Z.Q.); Department of Pharmacological and Pharmaceutical Sciences, College of Pharmacy, University of Houston, Houston, Texas (H.M.); Department of Pharmaceutics, School of Pharmaceutical Sciences, Southern Medical University, Guangzhou, Guangdong, PR China (D.P.M., W.Y.); and State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau (SAR), PR China (L.L.)
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Research ArticleArticle
UGT Metabolism of Esculetin and 4-Methylesculetin In Vitro
Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
Drug Metabolism and Disposition July 1, 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
Research ArticleArticle
UGT Metabolism of Esculetin and 4-Methylesculetin In Vitro
Lijun Zhu, Linlin Lu, Shan Zeng, Feifei Luo, Peimin Dai, Peng Wu, Ying Wang, Liang Liu, Ming Hu and Zhongqiu Liu
Drug Metabolism and Disposition July 1, 2015, 43 (7) 977-983; DOI: https://doi.org/10.1124/dmd.115.063552
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