Table of Contents

Articles

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  Quantitative Polymerase Chain Reaction Analysis of the Mouse Cyp2j Subfamily: Tissue Distribution and Regulation

  Joan P. Graves, Artiom Gruzdev, J. Alyce Bradbury, Laura M. DeGraff, Huiling Li, John S. House, Samantha L. Hoopes, Matthew L. Edin and Darryl C. Zeldin

  Drug Metabolism and Disposition August 2015, 43 (8) 1169-1180; DOI: https://doi.org/10.1124/dmd.115.064139
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  Ginsenosides Regulate PXR/NF-κB Signaling and Attenuate Dextran Sulfate Sodium–Induced Colitis

  Jun Zhang, Lijuan Cao, Hong Wang, Xuefang Cheng, Lin Wang, Lin Zhu, Tingting Yan, Yang Xie, Yuzheng Wu, Min Zhao, Sijing Ma, Mengqiu Wu, Guangji Wang and Haiping Hao

  Drug Metabolism and Disposition August 2015, 43 (8) 1181-1189; DOI: https://doi.org/10.1124/dmd.115.063800
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  Metabolism and Disposition of Cabozantinib in Healthy Male Volunteers and Pharmacologic Characterization of Its Major Metabolites

  Steven Lacy, Bih Hsu, Dale Miles, Dana Aftab, Ronghua Wang and Linh Nguyen

  Drug Metabolism and Disposition August 2015, 43 (8) 1190-1207; DOI: https://doi.org/10.1124/dmd.115.063610
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  Development of Murine Cyp3a Knockout Chimeric Mice with Humanized Liver

  Kota Kato, Masato Ohbuchi, Satoko Hamamura, Hiroki Ohshita, Yasuhiro Kazuki, Mitsuo Oshimura, Koya Sato, Naoyuki Nakada, Akio Kawamura, Takashi Usui, Hidetaka Kamimura and Chise Tateno

  Drug Metabolism and Disposition August 2015, 43 (8) 1208-1217; DOI: https://doi.org/10.1124/dmd.115.063479
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  Characterization of Species Differences in Tissue Diltiazem Deacetylation Identifies Ces2a as a Rat-Specific Diltiazem Deacetylase

  Takaya Kurokawa, Tatsuki Fukami and Miki Nakajima

  Drug Metabolism and Disposition August 2015, 43 (8) 1218-1225; DOI: https://doi.org/10.1124/dmd.115.064089
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  The CYP2C19 Intron 2 Branch Point SNP is the Ancestral Polymorphism Contributing to the Poor Metabolizer Phenotype in Livers with CYP2C19*35 and CYP2C19*2 Alleles

  Amarjit S. Chaudhry, Bhagwat Prasad, Yoshiyuki Shirasaka, Alison Fohner, David Finkelstein, Yiping Fan, Shuoguo Wang, Gang Wu, Eleni Aklillu, Sarah C. Sim, Kenneth E. Thummel and Erin G. Schuetz

  Drug Metabolism and Disposition August 2015, 43 (8) 1226-1235; DOI: https://doi.org/10.1124/dmd.115.064428
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  A Novel Loading Method for Doxycycline Liposomes for Intracellular Drug Delivery: Characterization of In Vitro and In Vivo Release Kinetics and Efficacy in a J774A.1 Cell Line Model of Mycobacterium smegmatis Infection

  Rebekah K. Franklin, Sarah A. Marcus, Adel M. Talaat, Butch K. KuKanich, Ruth Sullivan, Lisa A. Krugner-Higby and Timothy D. Heath

  Drug Metabolism and Disposition August 2015, 43 (8) 1236-1245; DOI: https://doi.org/10.1124/dmd.115.063602
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  Early Changes in Cytochrome P450s and Their Associated Arachidonic Acid Metabolites Play a Crucial Role in the Initiation of Cardiac Hypertrophy Induced by Isoproterenol

  Hassan N. Althurwi, Zaid H. Maayah, Osama H. Elshenawy and Ayman O. S. El-Kadi

  Drug Metabolism and Disposition August 2015, 43 (8) 1254-1266; DOI: https://doi.org/10.1124/dmd.115.063776
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  Pharmacokinetics and Metabolism of Delamanid, a Novel Anti-Tuberculosis Drug, in Animals and Humans: Importance of Albumin Metabolism In Vivo

  Katsunori Sasahara, Yoshihiko Shimokawa, Yukihiro Hirao, Noriyuki Koyama, Kazuyoshi Kitano, Masakazu Shibata and Ken Umehara

  Drug Metabolism and Disposition August 2015, 43 (8) 1267-1276; DOI: https://doi.org/10.1124/dmd.115.064527
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  Metabolic Mechanism of Delamanid, a New Anti-Tuberculosis Drug, in Human Plasma

  Yoshihiko Shimokawa, Katsunori Sasahara, Noriyuki Koyama, Kazuyoshi Kitano, Masakazu Shibata, Noriaki Yoda and Ken Umehara

  Drug Metabolism and Disposition August 2015, 43 (8) 1277-1283; DOI: https://doi.org/10.1124/dmd.115.064550
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  Variability in Expression of CYP3A5 in Human Fetal Liver

  Carrie A. Vyhlidal, Robin E. Pearce, Roger Gaedigk, Justina C. Calamia, Diana L. Shuster, Kenneth E. Thummel and J. Steven Leeder

  Drug Metabolism and Disposition August 2015, 43 (8) 1286-1293; DOI: https://doi.org/10.1124/dmd.115.064998