About the cover: In vitro induction parameters EC50 : panels A & B and Emax : panels C & D obtained with 6 human cryopreserved hepatocyte batches ( left ) and HepaRG cells (three independent thawing periods) ( right ), derived from test compound concentration –fold change in CYP3A4 mRNA curves. See the article by Boulenc et al. (dx.doi.org/10.1124/dmd.115.065581).