Index by author
October 01, 2016; Volume 44,Issue 10
A
Afkarian, Maryam
- You have accessAn Optimized Method for Protein Extraction from OCT-Embedded Human Kidney Tissue for Protein Quantification by LC-MS/MS ProteomicsMarc Vrana, Anne Goodling, Maryam Afkarian and Bhagwat PrasadDrug Metabolism and Disposition October 2016, 44 (10) 1692-1696; DOI: https://doi.org/10.1124/dmd.116.071522
Ando, Osamu
- You have accessAnalysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial AgentsAkiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu AndoDrug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654
B
Bernard, Apexa
- You have accessIn Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 ActivityJohan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly ChienDrug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672
Bittner, Florian
- You have accessDefining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme SystemBirte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd ClementDrug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845
Boer, Jason
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Bork, Bettina
- You have accessDefining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme SystemBirte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd ClementDrug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845
Bowman, Kevin J.
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Brown, Janice A.
- You have accessDetermination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated UptakeKeith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li DiDrug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837
Burt, Howard J.
- Open AccessAbundance of Hepatic Transporters in Caucasians: A Meta-AnalysisHoward J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle NeuhoffDrug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183
C
Callegari, Ernesto
- You have accessThe Use of In Vitro Data and Physiologically-Based Pharmacokinetic Modeling to Predict Drug Metabolite Exposure: Desipramine Exposure in Cytochrome P4502D6 Extensive and Poor Metabolizers Following Administration of ImipramineHoa Q. Nguyen, Ernesto Callegari and R. Scott ObachDrug Metabolism and Disposition October 2016, 44 (10) 1569-1578; DOI: https://doi.org/10.1124/dmd.116.071639
Catoire, Alexandre
- You have accessUtilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial AgentSu-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. MangoldDrug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108
Chen, Liangfu
- You have accessEvaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry PerspectiveOdette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing WangDrug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076
Chen, Shuqing
- You have accessMethylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular CarcinomaXiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing ChenDrug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243
Chen, Zhongjian
- You have accessMethylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular CarcinomaXiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing ChenDrug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243
Chien, Caly
- You have accessIn Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 ActivityJohan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly ChienDrug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672
Clark, Rebecca N.
- You have accessCytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of LapatinibJoanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. JacksonDrug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839
Clement, Bernd
- You have accessDefining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme SystemBirte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd ClementDrug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845
Combs, Andrew P.
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Crewe, H. Kim
- Open AccessAbundance of Hepatic Transporters in Caucasians: A Meta-AnalysisHoward J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle NeuhoffDrug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183
D
Di, Li
- You have accessDetermination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated UptakeKeith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li DiDrug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837
Diamond, Sharon
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Dong, Dong
- You have accessMorbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia InductionDong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian WuDrug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605
E
Einolf, Heidi J.
- You have accessEvaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry PerspectiveOdette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing WangDrug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076
Enokiya, Tomoyuki
- You have accessLansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro OkudaDrug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722
Erion, Derek M.
- You have accessDetermination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated UptakeKeith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li DiDrug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837
F
Fahmi, Odette A.
- You have accessEvaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry PerspectiveOdette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing WangDrug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076
Flarakos, Jimmy
- You have accessUtilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial AgentSu-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. MangoldDrug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108
Forseth, Ry R.
- You have accessUtilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial AgentSu-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. MangoldDrug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108
Frietze, William
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Fujimoto, Hajime
- You have accessLansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro OkudaDrug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722
G
Galya, Laurine
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Ge, Lele
- You have accessMethylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular CarcinomaXiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing ChenDrug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243
Gill, Katherine L.
- Open AccessAbundance of Hepatic Transporters in Caucasians: A Meta-AnalysisHoward J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle NeuhoffDrug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183
Goldman, Jennifer L.
- You have accessBioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver MicrosomesJennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. HanzlikDrug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041
Gonzalez, Martha
- You have accessIn Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 ActivityJohan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly ChienDrug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672
Goodling, Anne
- You have accessAn Optimized Method for Protein Extraction from OCT-Embedded Human Kidney Tissue for Protein Quantification by LC-MS/MS ProteomicsMarc Vrana, Anne Goodling, Maryam Afkarian and Bhagwat PrasadDrug Metabolism and Disposition October 2016, 44 (10) 1692-1696; DOI: https://doi.org/10.1124/dmd.116.071522
Gorgoglione, Matthew F.
- You have accessDetermination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated UptakeKeith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li DiDrug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837
Gosset, James
- You have accessDetermination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated UptakeKeith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li DiDrug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837
Grube, Markus
- You have accessExpression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial TherapyAndrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus GrubeDrug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807
H
Hamada, Yugo
- You have accessLansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro OkudaDrug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722
Hanzlik, Robert P.
- You have accessBioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver MicrosomesJennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. HanzlikDrug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041
Harwood, Matthew D.
- Open AccessAbundance of Hepatic Transporters in Caucasians: A Meta-AnalysisHoward J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle NeuhoffDrug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183
Havemeyer, Antje
- You have accessDefining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme SystemBirte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd ClementDrug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845
He, Handan
- You have accessUtilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial AgentSu-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. MangoldDrug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108
Hop, Cornelis E. C. A.
- You have accessAn Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin XuDrug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017
Huard, Kim
- You have accessDetermination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated UptakeKeith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li DiDrug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837
Hubeny, Andrea
- You have accessExpression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial TherapyAndrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus GrubeDrug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807
Huskey, Su-Er W.
- You have accessUtilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial AgentSu-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. MangoldDrug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108
I
Ieiri, Ichiro
- You have accessClarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro InformationSoo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276
Ikemura, Kenji
- You have accessLansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro OkudaDrug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722
Inoue, Shin-ichi
- You have accessAnalysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial AgentsAkiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu AndoDrug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654
Irie, Shin
- You have accessClarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro InformationSoo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276
Isoherranen, Nina
- Open AccessStereoselective Metabolism of Bupropion to OH-bupropion, Threohydrobupropion, Erythrohydrobupropion, and 4′-OH-bupropion in vitroJennifer E. Sager, Lauren S. L. Price and Nina IsoherranenDrug Metabolism and Disposition October 2016, 44 (10) 1709-1719; DOI: https://doi.org/10.1124/dmd.116.072363
Iwamoto, Takuya
- You have accessLansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro OkudaDrug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722
Iwao, Takahiro
- You have accessCharacteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem CellsNao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide MatsunagaDrug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336
J
Jackson, Klarissa D.
- You have accessCytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of LapatinibJoanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. JacksonDrug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839
Jedlitschky, Gabriele
- You have accessExpression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial TherapyAndrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus GrubeDrug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807
Jian, Zhigang
- You have accessUtilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial AgentSu-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. MangoldDrug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108
Jiao, James
- You have accessIn Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 ActivityJohan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly ChienDrug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672
K
Katano, Takahiro
- You have accessCharacteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem CellsNao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide MatsunagaDrug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336
Kaya, Chinatsu
- You have accessLansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro OkudaDrug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722
Keiser, Markus
- You have accessExpression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial TherapyAndrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus GrubeDrug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807
Kelly, Edward J.
- You have accessSpecies Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ ToxicityOliver T. Parkinson, Aaron M. Teitelbaum, Dale Whittington, Edward J. Kelly and Allan E. RettieDrug Metabolism and Disposition October 2016, 44 (10) 1598-1602; DOI: https://doi.org/10.1124/dmd.116.070003
Kerns, Edward
- You have accessAn Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin XuDrug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017
Kim, Soo-Jin
- You have accessClarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro InformationSoo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276
Kimura, Miyuki
- You have accessClarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro InformationSoo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276
Kimura, Takako
- You have accessAnalysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial AgentsAkiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu AndoDrug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654
Kobayashi, Tetsu
- You have accessLansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro OkudaDrug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722
Kodama, Nao
- You have accessCharacteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem CellsNao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide MatsunagaDrug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336
Koen, Yakov M.
- You have accessBioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver MicrosomesJennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. HanzlikDrug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041
Kong, Sisi
- You have accessMethylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular CarcinomaXiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing ChenDrug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243
Kroemer, Heyo K.
- You have accessExpression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial TherapyAndrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus GrubeDrug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807
Kusuhara, Hiroyuki
- You have accessAnalysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial AgentsAkiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu AndoDrug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654
- You have accessClarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro InformationSoo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276
L
Lee, Fiona
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Lee, Jonghwa
- You have accessDrug Transport by the Blood–Aqueous Humor Barrier of the EyeJonghwa Lee and Ryan M. PelisDrug Metabolism and Disposition October 2016, 44 (10) 1675-1681; DOI: https://doi.org/10.1124/dmd.116.069369
Leeder, James S.
- You have accessBioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver MicrosomesJennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. HanzlikDrug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041
Li, Hongmei
- You have accessUtilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial AgentSu-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. MangoldDrug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108
Li, Jiayang
- You have accessMorbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia InductionDong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian WuDrug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605
Li, Kelin
- You have accessBioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver MicrosomesJennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. HanzlikDrug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041
Li, Zhenhong
- You have accessDetermination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated UptakeKeith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li DiDrug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837
Liu, Jie
- You have accessMorbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia InductionDong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian WuDrug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605
Liu, Wenhui
- You have accessMethylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular CarcinomaXiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing ChenDrug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243
M
Maeda, Kazuya
- You have accessClarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro InformationSoo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276
Mangold, James B.
- You have accessUtilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial AgentSu-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. MangoldDrug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108
Matsunaga, Tamihide
- You have accessCharacteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem CellsNao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide MatsunagaDrug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336
McKew, John
- You have accessAn Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin XuDrug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017
Mendel, Ralf
- You have accessDefining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme SystemBirte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd ClementDrug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845
Monbaliu, Johan
- You have accessIn Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 ActivityJohan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly ChienDrug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672
Muraki, Yuichi
- You have accessLansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro OkudaDrug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722
N
Nakahara, Hiroki
- You have accessLansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro OkudaDrug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722
Nedza, Frank M.
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Neuhoff, Sibylle
- Open AccessAbundance of Hepatic Transporters in Caucasians: A Meta-AnalysisHoward J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle NeuhoffDrug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183
Nguyen, Dac-Trung
- You have accessAn Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin XuDrug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017
Nguyen, Hoa Q.
- You have accessThe Use of In Vitro Data and Physiologically-Based Pharmacokinetic Modeling to Predict Drug Metabolite Exposure: Desipramine Exposure in Cytochrome P4502D6 Extensive and Poor Metabolizers Following Administration of ImipramineHoa Q. Nguyen, Ernesto Callegari and R. Scott ObachDrug Metabolism and Disposition October 2016, 44 (10) 1569-1578; DOI: https://doi.org/10.1124/dmd.116.071639
Niosi, Mark
- You have accessDetermination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated UptakeKeith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li DiDrug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837
O
Obach, R. Scott
- You have accessThe Use of In Vitro Data and Physiologically-Based Pharmacokinetic Modeling to Predict Drug Metabolite Exposure: Desipramine Exposure in Cytochrome P4502D6 Extensive and Poor Metabolizers Following Administration of ImipramineHoa Q. Nguyen, Ernesto Callegari and R. Scott ObachDrug Metabolism and Disposition October 2016, 44 (10) 1569-1578; DOI: https://doi.org/10.1124/dmd.116.071639
- You have accessAn Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin XuDrug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017
Ohta, Kinya
- You have accessCharacteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem CellsNao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide MatsunagaDrug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336
Okuda, Masahiro
- You have accessLansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro OkudaDrug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722
Oswald, Stefan
- You have accessExpression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial TherapyAndrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus GrubeDrug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807
P
Palamanda, Jairam
- You have accessEvaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry PerspectiveOdette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing WangDrug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076
Parkinson, Oliver T.
- You have accessSpecies Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ ToxicityOliver T. Parkinson, Aaron M. Teitelbaum, Dale Whittington, Edward J. Kelly and Allan E. RettieDrug Metabolism and Disposition October 2016, 44 (10) 1598-1602; DOI: https://doi.org/10.1124/dmd.116.070003
Pelis, Ryan M.
- You have accessDrug Transport by the Blood–Aqueous Humor Barrier of the EyeJonghwa Lee and Ryan M. PelisDrug Metabolism and Disposition October 2016, 44 (10) 1675-1681; DOI: https://doi.org/10.1124/dmd.116.069369
Peng, Xuemei
- You have accessMorbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia InductionDong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian WuDrug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605
Plitzko, Birte
- You have accessDefining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme SystemBirte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd ClementDrug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845
Prasad, Bhagwat
- You have accessAn Optimized Method for Protein Extraction from OCT-Embedded Human Kidney Tissue for Protein Quantification by LC-MS/MS ProteomicsMarc Vrana, Anne Goodling, Maryam Afkarian and Bhagwat PrasadDrug Metabolism and Disposition October 2016, 44 (10) 1692-1696; DOI: https://doi.org/10.1124/dmd.116.071522
Price, Lauren S. L.
- Open AccessStereoselective Metabolism of Bupropion to OH-bupropion, Threohydrobupropion, Erythrohydrobupropion, and 4′-OH-bupropion in vitroJennifer E. Sager, Lauren S. L. Price and Nina IsoherranenDrug Metabolism and Disposition October 2016, 44 (10) 1709-1719; DOI: https://doi.org/10.1124/dmd.116.072363
Q
Qian, Hao
- You have accessMorbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia InductionDong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian WuDrug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605
R
Ramsden, Diane
- You have accessEvaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry PerspectiveOdette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing WangDrug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076
Ray, Tapan
- You have accessUtilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial AgentSu-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. MangoldDrug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108
Rettie, Allan E.
- You have accessCytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of LapatinibJoanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. JacksonDrug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839
- You have accessSpecies Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ ToxicityOliver T. Parkinson, Aaron M. Teitelbaum, Dale Whittington, Edward J. Kelly and Allan E. RettieDrug Metabolism and Disposition October 2016, 44 (10) 1598-1602; DOI: https://doi.org/10.1124/dmd.116.070003
Riccardi, Keith
- You have accessDetermination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated UptakeKeith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li DiDrug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837
Riedmaier, Arian Emami
- Open AccessAbundance of Hepatic Transporters in Caucasians: A Meta-AnalysisHoward J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle NeuhoffDrug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183
Rogers, Steven A.
- You have accessBioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver MicrosomesJennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. HanzlikDrug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041
S
Sager, Jennifer E.
- Open AccessStereoselective Metabolism of Bupropion to OH-bupropion, Threohydrobupropion, Erythrohydrobupropion, and 4′-OH-bupropion in vitroJennifer E. Sager, Lauren S. L. Price and Nina IsoherranenDrug Metabolism and Disposition October 2016, 44 (10) 1709-1719; DOI: https://doi.org/10.1124/dmd.116.072363
Sensenhauser, Carlo
- You have accessIn Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 ActivityJohan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly ChienDrug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672
Shah, Pranav
- You have accessAn Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin XuDrug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017
Shebley, Mohamad
- You have accessEvaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry PerspectiveOdette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing WangDrug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076
Shi, Jack G.
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Siegmund, Werner
- You have accessExpression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial TherapyAndrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus GrubeDrug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807
Simeonov, Anton
- You have accessAn Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin XuDrug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017
Sinz, Michael W.
- You have accessEvaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry PerspectiveOdette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing WangDrug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076
Smit, Johan W.
- You have accessIn Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 ActivityJohan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly ChienDrug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672
Snoeys, Jan
- You have accessIn Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 ActivityJohan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly ChienDrug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672
Stieltjes, Hans
- You have accessIn Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 ActivityJohan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly ChienDrug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672
Sugiyama, Yuichi
- You have accessClarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro InformationSoo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276
T
Takakusa, Hideo
- You have accessAnalysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial AgentsAkiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu AndoDrug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654
Tang, Xiaojing
- You have accessMethylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular CarcinomaXiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing ChenDrug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243
Teitelbaum, Aaron M.
- You have accessSpecies Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ ToxicityOliver T. Parkinson, Aaron M. Teitelbaum, Dale Whittington, Edward J. Kelly and Allan E. RettieDrug Metabolism and Disposition October 2016, 44 (10) 1598-1602; DOI: https://doi.org/10.1124/dmd.116.070003
Towles, Joanna K.
- You have accessCytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of LapatinibJoanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. JacksonDrug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839
U
Uttamsingh, Vinita
- You have accessCytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of LapatinibJoanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. JacksonDrug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839
V
Vrana, Marc
- You have accessAn Optimized Method for Protein Extraction from OCT-Embedded Human Kidney Tissue for Protein Quantification by LC-MS/MS ProteomicsMarc Vrana, Anne Goodling, Maryam Afkarian and Bhagwat PrasadDrug Metabolism and Disposition October 2016, 44 (10) 1692-1696; DOI: https://doi.org/10.1124/dmd.116.071522
W
Wahlin, Michelle D.
- You have accessCytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of LapatinibJoanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. JacksonDrug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839
Wang, Amy Q.
- You have accessAn Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin XuDrug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017
Wang, Hongbing
- You have accessEvaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry PerspectiveOdette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing WangDrug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076
Watanabe, Akiko
- You have accessAnalysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial AgentsAkiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu AndoDrug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654
Whittington, Dale
- You have accessSpecies Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ ToxicityOliver T. Parkinson, Aaron M. Teitelbaum, Dale Whittington, Edward J. Kelly and Allan E. RettieDrug Metabolism and Disposition October 2016, 44 (10) 1598-1602; DOI: https://doi.org/10.1124/dmd.116.070003
Wu, Baojian
- You have accessMorbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia InductionDong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian WuDrug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605
Wynant, Inneke
- You have accessIn Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 ActivityJohan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly ChienDrug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672
X
Xu, Xin
- You have accessAn Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin XuDrug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017
Xu, Yingchun
- You have accessMethylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular CarcinomaXiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing ChenDrug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243
Y
Yang, Xiaoqing
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Yeleswaram, Swamy
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Yoshikado, Takashi
- You have accessClarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro InformationSoo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi SugiyamaDrug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276
Young-Sciame, Ruth
- You have accessRoles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in HumansJason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon DiamondDrug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Yuasa, Hiroaki
- You have accessCharacteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem CellsNao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide MatsunagaDrug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336
Z
Zakharov, Alexey
- You have accessAn Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis SoftwarePranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin XuDrug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017
Zeng, Su
- You have accessMethylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular CarcinomaXiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing ChenDrug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243
Zhang, Jin
- You have accessUtilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial AgentSu-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. MangoldDrug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108
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