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Index by author

October 01, 2016; Volume 44,Issue 10

A

  1. Afkarian, Maryam

    1. An Optimized Method for Protein Extraction from OCT-Embedded Human Kidney Tissue for Protein Quantification by LC-MS/MS Proteomics
      Marc Vrana, Anne Goodling, Maryam Afkarian and Bhagwat Prasad
      Drug Metabolism and Disposition October 2016, 44 (10) 1692-1696; DOI: https://doi.org/10.1124/dmd.116.071522

  2. Ando, Osamu

    1. Analysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial Agents
      Akiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu Ando
      Drug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654

B

  1. Bernard, Apexa

    1. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity
      Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly Chien
      Drug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672

  2. Bittner, Florian

    1. Defining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme System
      Birte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd Clement
      Drug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845

  3. Boer, Jason

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  4. Bork, Bettina

    1. Defining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme System
      Birte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd Clement
      Drug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845

  5. Bowman, Kevin J.

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  6. Brown, Janice A.

    1. Determination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated Uptake
      Keith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li Di
      Drug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837

  7. Burt, Howard J.

    1. Open Access
      Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis
      Howard J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle Neuhoff
      Drug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183

C

  1. Callegari, Ernesto

    1. The Use of In Vitro Data and Physiologically-Based Pharmacokinetic Modeling to Predict Drug Metabolite Exposure: Desipramine Exposure in Cytochrome P4502D6 Extensive and Poor Metabolizers Following Administration of Imipramine
      Hoa Q. Nguyen, Ernesto Callegari and R. Scott Obach
      Drug Metabolism and Disposition October 2016, 44 (10) 1569-1578; DOI: https://doi.org/10.1124/dmd.116.071639

  2. Catoire, Alexandre

    1. Utilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial Agent
      Su-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. Mangold
      Drug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108

  3. Chen, Liangfu

    1. Evaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry Perspective
      Odette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing Wang
      Drug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076

  4. Chen, Shuqing

    1. Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular Carcinoma
      Xiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing Chen
      Drug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243

  5. Chen, Zhongjian

    1. Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular Carcinoma
      Xiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing Chen
      Drug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243

  6. Chien, Caly

    1. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity
      Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly Chien
      Drug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672

  7. Clark, Rebecca N.

    1. Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of Lapatinib
      Joanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. Jackson
      Drug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839

  8. Clement, Bernd

    1. Defining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme System
      Birte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd Clement
      Drug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845

  9. Combs, Andrew P.

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  10. Crewe, H. Kim

    1. Open Access
      Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis
      Howard J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle Neuhoff
      Drug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183

D

  1. Di, Li

    1. Determination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated Uptake
      Keith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li Di
      Drug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837

  2. Diamond, Sharon

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  3. Dong, Dong

    1. Morbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia Induction
      Dong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian Wu
      Drug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605

E

  1. Einolf, Heidi J.

    1. Evaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry Perspective
      Odette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing Wang
      Drug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076

  2. Enokiya, Tomoyuki

    1. Lansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3
      Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro Okuda
      Drug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722

  3. Erion, Derek M.

    1. Determination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated Uptake
      Keith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li Di
      Drug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837

F

  1. Fahmi, Odette A.

    1. Evaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry Perspective
      Odette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing Wang
      Drug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076

  2. Flarakos, Jimmy

    1. Utilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial Agent
      Su-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. Mangold
      Drug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108

  3. Forseth, Ry R.

    1. Utilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial Agent
      Su-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. Mangold
      Drug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108

  4. Frietze, William

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  5. Fujimoto, Hajime

    1. Lansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3
      Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro Okuda
      Drug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722

G

  1. Galya, Laurine

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  2. Ge, Lele

    1. Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular Carcinoma
      Xiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing Chen
      Drug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243

  3. Gill, Katherine L.

    1. Open Access
      Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis
      Howard J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle Neuhoff
      Drug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183

  4. Goldman, Jennifer L.

    1. Bioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver Microsomes
      Jennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. Hanzlik
      Drug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041

  5. Gonzalez, Martha

    1. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity
      Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly Chien
      Drug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672

  6. Goodling, Anne

    1. An Optimized Method for Protein Extraction from OCT-Embedded Human Kidney Tissue for Protein Quantification by LC-MS/MS Proteomics
      Marc Vrana, Anne Goodling, Maryam Afkarian and Bhagwat Prasad
      Drug Metabolism and Disposition October 2016, 44 (10) 1692-1696; DOI: https://doi.org/10.1124/dmd.116.071522

  7. Gorgoglione, Matthew F.

    1. Determination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated Uptake
      Keith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li Di
      Drug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837

  8. Gosset, James

    1. Determination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated Uptake
      Keith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li Di
      Drug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837

  9. Grube, Markus

    1. Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy
      Andrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus Grube
      Drug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807

H

  1. Hamada, Yugo

    1. Lansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3
      Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro Okuda
      Drug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722

  2. Hanzlik, Robert P.

    1. Bioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver Microsomes
      Jennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. Hanzlik
      Drug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041

  3. Harwood, Matthew D.

    1. Open Access
      Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis
      Howard J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle Neuhoff
      Drug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183

  4. Havemeyer, Antje

    1. Defining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme System
      Birte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd Clement
      Drug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845

  5. He, Handan

    1. Utilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial Agent
      Su-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. Mangold
      Drug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108

  6. Hop, Cornelis E. C. A.

    1. An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software
      Pranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin Xu
      Drug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017

  7. Huard, Kim

    1. Determination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated Uptake
      Keith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li Di
      Drug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837

  8. Hubeny, Andrea

    1. Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy
      Andrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus Grube
      Drug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807

  9. Huskey, Su-Er W.

    1. Utilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial Agent
      Su-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. Mangold
      Drug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108

I

  1. Ieiri, Ichiro

    1. Clarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information
      Soo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276

  2. Ikemura, Kenji

    1. Lansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3
      Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro Okuda
      Drug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722

  3. Inoue, Shin-ichi

    1. Analysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial Agents
      Akiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu Ando
      Drug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654

  4. Irie, Shin

    1. Clarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information
      Soo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276

  5. Isoherranen, Nina

    1. Open Access
      Stereoselective Metabolism of Bupropion to OH-bupropion, Threohydrobupropion, Erythrohydrobupropion, and 4′-OH-bupropion in vitro
      Jennifer E. Sager, Lauren S. L. Price and Nina Isoherranen
      Drug Metabolism and Disposition October 2016, 44 (10) 1709-1719; DOI: https://doi.org/10.1124/dmd.116.072363

  6. Iwamoto, Takuya

    1. Lansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3
      Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro Okuda
      Drug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722

  7. Iwao, Takahiro

    1. Characteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells
      Nao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide Matsunaga
      Drug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336

J

  1. Jackson, Klarissa D.

    1. Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of Lapatinib
      Joanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. Jackson
      Drug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839

  2. Jedlitschky, Gabriele

    1. Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy
      Andrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus Grube
      Drug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807

  3. Jian, Zhigang

    1. Utilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial Agent
      Su-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. Mangold
      Drug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108

  4. Jiao, James

    1. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity
      Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly Chien
      Drug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672

K

  1. Katano, Takahiro

    1. Characteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells
      Nao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide Matsunaga
      Drug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336

  2. Kaya, Chinatsu

    1. Lansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3
      Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro Okuda
      Drug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722

  3. Keiser, Markus

    1. Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy
      Andrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus Grube
      Drug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807

  4. Kelly, Edward J.

    1. Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity
      Oliver T. Parkinson, Aaron M. Teitelbaum, Dale Whittington, Edward J. Kelly and Allan E. Rettie
      Drug Metabolism and Disposition October 2016, 44 (10) 1598-1602; DOI: https://doi.org/10.1124/dmd.116.070003

  5. Kerns, Edward

    1. An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software
      Pranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin Xu
      Drug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017

  6. Kim, Soo-Jin

    1. Clarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information
      Soo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276

  7. Kimura, Miyuki

    1. Clarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information
      Soo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276

  8. Kimura, Takako

    1. Analysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial Agents
      Akiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu Ando
      Drug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654

  9. Kobayashi, Tetsu

    1. Lansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3
      Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro Okuda
      Drug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722

  10. Kodama, Nao

    1. Characteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells
      Nao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide Matsunaga
      Drug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336

  11. Koen, Yakov M.

    1. Bioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver Microsomes
      Jennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. Hanzlik
      Drug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041

  12. Kong, Sisi

    1. Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular Carcinoma
      Xiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing Chen
      Drug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243

  13. Kroemer, Heyo K.

    1. Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy
      Andrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus Grube
      Drug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807

  14. Kusuhara, Hiroyuki

    1. Analysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial Agents
      Akiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu Ando
      Drug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654
    2. Clarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information
      Soo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276

L

  1. Lee, Fiona

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  2. Lee, Jonghwa

    1. Drug Transport by the Blood–Aqueous Humor Barrier of the Eye
      Jonghwa Lee and Ryan M. Pelis
      Drug Metabolism and Disposition October 2016, 44 (10) 1675-1681; DOI: https://doi.org/10.1124/dmd.116.069369

  3. Leeder, James S.

    1. Bioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver Microsomes
      Jennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. Hanzlik
      Drug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041

  4. Li, Hongmei

    1. Utilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial Agent
      Su-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. Mangold
      Drug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108

  5. Li, Jiayang

    1. Morbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia Induction
      Dong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian Wu
      Drug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605

  6. Li, Kelin

    1. Bioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver Microsomes
      Jennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. Hanzlik
      Drug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041

  7. Li, Zhenhong

    1. Determination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated Uptake
      Keith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li Di
      Drug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837

  8. Liu, Jie

    1. Morbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia Induction
      Dong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian Wu
      Drug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605

  9. Liu, Wenhui

    1. Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular Carcinoma
      Xiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing Chen
      Drug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243

M

  1. Maeda, Kazuya

    1. Clarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information
      Soo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276

  2. Mangold, James B.

    1. Utilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial Agent
      Su-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. Mangold
      Drug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108

  3. Matsunaga, Tamihide

    1. Characteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells
      Nao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide Matsunaga
      Drug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336

  4. McKew, John

    1. An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software
      Pranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin Xu
      Drug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017

  5. Mendel, Ralf

    1. Defining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme System
      Birte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd Clement
      Drug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845

  6. Monbaliu, Johan

    1. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity
      Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly Chien
      Drug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672

  7. Muraki, Yuichi

    1. Lansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3
      Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro Okuda
      Drug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722

N

  1. Nakahara, Hiroki

    1. Lansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3
      Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro Okuda
      Drug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722

  2. Nedza, Frank M.

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  3. Neuhoff, Sibylle

    1. Open Access
      Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis
      Howard J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle Neuhoff
      Drug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183

  4. Nguyen, Dac-Trung

    1. An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software
      Pranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin Xu
      Drug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017

  5. Nguyen, Hoa Q.

    1. The Use of In Vitro Data and Physiologically-Based Pharmacokinetic Modeling to Predict Drug Metabolite Exposure: Desipramine Exposure in Cytochrome P4502D6 Extensive and Poor Metabolizers Following Administration of Imipramine
      Hoa Q. Nguyen, Ernesto Callegari and R. Scott Obach
      Drug Metabolism and Disposition October 2016, 44 (10) 1569-1578; DOI: https://doi.org/10.1124/dmd.116.071639

  6. Niosi, Mark

    1. Determination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated Uptake
      Keith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li Di
      Drug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837

O

  1. Obach, R. Scott

    1. The Use of In Vitro Data and Physiologically-Based Pharmacokinetic Modeling to Predict Drug Metabolite Exposure: Desipramine Exposure in Cytochrome P4502D6 Extensive and Poor Metabolizers Following Administration of Imipramine
      Hoa Q. Nguyen, Ernesto Callegari and R. Scott Obach
      Drug Metabolism and Disposition October 2016, 44 (10) 1569-1578; DOI: https://doi.org/10.1124/dmd.116.071639
    2. An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software
      Pranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin Xu
      Drug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017

  2. Ohta, Kinya

    1. Characteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells
      Nao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide Matsunaga
      Drug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336

  3. Okuda, Masahiro

    1. Lansoprazole Exacerbates Pemetrexed-Mediated Hematologic Toxicity by Competitive Inhibition of Renal Basolateral Human Organic Anion Transporter 3
      Kenji Ikemura, Yugo Hamada, Chinatsu Kaya, Tomoyuki Enokiya, Yuichi Muraki, Hiroki Nakahara, Hajime Fujimoto, Tetsu Kobayashi, Takuya Iwamoto and Masahiro Okuda
      Drug Metabolism and Disposition October 2016, 44 (10) 1543-1549; DOI: https://doi.org/10.1124/dmd.116.070722

  4. Oswald, Stefan

    1. Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy
      Andrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus Grube
      Drug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807

P

  1. Palamanda, Jairam

    1. Evaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry Perspective
      Odette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing Wang
      Drug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076

  2. Parkinson, Oliver T.

    1. Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity
      Oliver T. Parkinson, Aaron M. Teitelbaum, Dale Whittington, Edward J. Kelly and Allan E. Rettie
      Drug Metabolism and Disposition October 2016, 44 (10) 1598-1602; DOI: https://doi.org/10.1124/dmd.116.070003

  3. Pelis, Ryan M.

    1. Drug Transport by the Blood–Aqueous Humor Barrier of the Eye
      Jonghwa Lee and Ryan M. Pelis
      Drug Metabolism and Disposition October 2016, 44 (10) 1675-1681; DOI: https://doi.org/10.1124/dmd.116.069369

  4. Peng, Xuemei

    1. Morbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia Induction
      Dong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian Wu
      Drug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605

  5. Plitzko, Birte

    1. Defining the Role of the NADH–Cytochrome-b5 Reductase 3 in the Mitochondrial Amidoxime Reducing Component Enzyme System
      Birte Plitzko, Antje Havemeyer, Bettina Bork, Florian Bittner, Ralf Mendel and Bernd Clement
      Drug Metabolism and Disposition October 2016, 44 (10) 1617-1621; DOI: https://doi.org/10.1124/dmd.116.071845

  6. Prasad, Bhagwat

    1. An Optimized Method for Protein Extraction from OCT-Embedded Human Kidney Tissue for Protein Quantification by LC-MS/MS Proteomics
      Marc Vrana, Anne Goodling, Maryam Afkarian and Bhagwat Prasad
      Drug Metabolism and Disposition October 2016, 44 (10) 1692-1696; DOI: https://doi.org/10.1124/dmd.116.071522

  7. Price, Lauren S. L.

    1. Open Access
      Stereoselective Metabolism of Bupropion to OH-bupropion, Threohydrobupropion, Erythrohydrobupropion, and 4′-OH-bupropion in vitro
      Jennifer E. Sager, Lauren S. L. Price and Nina Isoherranen
      Drug Metabolism and Disposition October 2016, 44 (10) 1709-1719; DOI: https://doi.org/10.1124/dmd.116.072363

Q

  1. Qian, Hao

    1. Morbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia Induction
      Dong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian Wu
      Drug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605

R

  1. Ramsden, Diane

    1. Evaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry Perspective
      Odette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing Wang
      Drug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076

  2. Ray, Tapan

    1. Utilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial Agent
      Su-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. Mangold
      Drug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108

  3. Rettie, Allan E.

    1. Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of Lapatinib
      Joanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. Jackson
      Drug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839
    2. Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity
      Oliver T. Parkinson, Aaron M. Teitelbaum, Dale Whittington, Edward J. Kelly and Allan E. Rettie
      Drug Metabolism and Disposition October 2016, 44 (10) 1598-1602; DOI: https://doi.org/10.1124/dmd.116.070003

  4. Riccardi, Keith

    1. Determination of Unbound Partition Coefficient and in Vitro–in Vivo Extrapolation for SLC13A Transporter–Mediated Uptake
      Keith Riccardi, Zhenhong Li, Janice A. Brown, Matthew F. Gorgoglione, Mark Niosi, James Gosset, Kim Huard, Derek M. Erion and Li Di
      Drug Metabolism and Disposition October 2016, 44 (10) 1633-1642; DOI: https://doi.org/10.1124/dmd.116.071837

  5. Riedmaier, Arian Emami

    1. Open Access
      Abundance of Hepatic Transporters in Caucasians: A Meta-Analysis
      Howard J. Burt, Arian Emami Riedmaier, Matthew D. Harwood, H. Kim Crewe, Katherine L. Gill and Sibylle Neuhoff
      Drug Metabolism and Disposition October 2016, 44 (10) 1550-1561; DOI: https://doi.org/10.1124/dmd.116.071183

  6. Rogers, Steven A.

    1. Bioactivation of Trimethoprim to Protein-Reactive Metabolites in Human Liver Microsomes
      Jennifer L. Goldman, Yakov M. Koen, Steven A. Rogers, Kelin Li, James S. Leeder and Robert P. Hanzlik
      Drug Metabolism and Disposition October 2016, 44 (10) 1603-1607; DOI: https://doi.org/10.1124/dmd.116.072041

S

  1. Sager, Jennifer E.

    1. Open Access
      Stereoselective Metabolism of Bupropion to OH-bupropion, Threohydrobupropion, Erythrohydrobupropion, and 4′-OH-bupropion in vitro
      Jennifer E. Sager, Lauren S. L. Price and Nina Isoherranen
      Drug Metabolism and Disposition October 2016, 44 (10) 1709-1719; DOI: https://doi.org/10.1124/dmd.116.072363

  2. Sensenhauser, Carlo

    1. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity
      Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly Chien
      Drug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672

  3. Shah, Pranav

    1. An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software
      Pranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin Xu
      Drug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017

  4. Shebley, Mohamad

    1. Evaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry Perspective
      Odette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing Wang
      Drug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076

  5. Shi, Jack G.

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  6. Siegmund, Werner

    1. Expression of Organic Anion Transporting Polypeptide 1A2 in Red Blood Cells and Its Potential Impact on Antimalarial Therapy
      Andrea Hubeny, Markus Keiser, Stefan Oswald, Gabriele Jedlitschky, Heyo K. Kroemer, Werner Siegmund and Markus Grube
      Drug Metabolism and Disposition October 2016, 44 (10) 1562-1568; DOI: https://doi.org/10.1124/dmd.116.069807

  7. Simeonov, Anton

    1. An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software
      Pranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin Xu
      Drug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017

  8. Sinz, Michael W.

    1. Evaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry Perspective
      Odette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing Wang
      Drug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076

  9. Smit, Johan W.

    1. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity
      Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly Chien
      Drug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672

  10. Snoeys, Jan

    1. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity
      Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly Chien
      Drug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672

  11. Stieltjes, Hans

    1. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity
      Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly Chien
      Drug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672

  12. Sugiyama, Yuichi

    1. Clarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information
      Soo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276

T

  1. Takakusa, Hideo

    1. Analysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial Agents
      Akiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu Ando
      Drug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654

  2. Tang, Xiaojing

    1. Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular Carcinoma
      Xiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing Chen
      Drug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243

  3. Teitelbaum, Aaron M.

    1. Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity
      Oliver T. Parkinson, Aaron M. Teitelbaum, Dale Whittington, Edward J. Kelly and Allan E. Rettie
      Drug Metabolism and Disposition October 2016, 44 (10) 1598-1602; DOI: https://doi.org/10.1124/dmd.116.070003

  4. Towles, Joanna K.

    1. Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of Lapatinib
      Joanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. Jackson
      Drug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839

U

  1. Uttamsingh, Vinita

    1. Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of Lapatinib
      Joanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. Jackson
      Drug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839

V

  1. Vrana, Marc

    1. An Optimized Method for Protein Extraction from OCT-Embedded Human Kidney Tissue for Protein Quantification by LC-MS/MS Proteomics
      Marc Vrana, Anne Goodling, Maryam Afkarian and Bhagwat Prasad
      Drug Metabolism and Disposition October 2016, 44 (10) 1692-1696; DOI: https://doi.org/10.1124/dmd.116.071522

W

  1. Wahlin, Michelle D.

    1. Cytochrome P450 3A4 and CYP3A5-Catalyzed Bioactivation of Lapatinib
      Joanna K. Towles, Rebecca N. Clark, Michelle D. Wahlin, Vinita Uttamsingh, Allan E. Rettie and Klarissa D. Jackson
      Drug Metabolism and Disposition October 2016, 44 (10) 1584-1597; DOI: https://doi.org/10.1124/dmd.116.070839

  2. Wang, Amy Q.

    1. An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software
      Pranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin Xu
      Drug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017

  3. Wang, Hongbing

    1. Evaluation of CYP2B6 Induction and Prediction of Clinical Drug–Drug Interactions: Considerations from the IQ Consortium Induction Working Group—An Industry Perspective
      Odette A. Fahmi, Mohamad Shebley, Jairam Palamanda, Michael W. Sinz, Diane Ramsden, Heidi J. Einolf, Liangfu Chen and Hongbing Wang
      Drug Metabolism and Disposition October 2016, 44 (10) 1720-1730; DOI: https://doi.org/10.1124/dmd.116.071076

  4. Watanabe, Akiko

    1. Analysis of Mechanism-Based Inhibition of CYP 3A4 by a Series of Fluoroquinolone Antibacterial Agents
      Akiko Watanabe, Hideo Takakusa, Takako Kimura, Shin-ichi Inoue, Hiroyuki Kusuhara and Osamu Ando
      Drug Metabolism and Disposition October 2016, 44 (10) 1608-1616; DOI: https://doi.org/10.1124/dmd.116.071654

  5. Whittington, Dale

    1. Species Differences in Microsomal Oxidation and Glucuronidation of 4-Ipomeanol: Relationship to Target Organ Toxicity
      Oliver T. Parkinson, Aaron M. Teitelbaum, Dale Whittington, Edward J. Kelly and Allan E. Rettie
      Drug Metabolism and Disposition October 2016, 44 (10) 1598-1602; DOI: https://doi.org/10.1124/dmd.116.070003

  6. Wu, Baojian

    1. Morbid Obesity Alters Both Pharmacokinetics and Pharmacodynamics of Propofol: Dosing Recommendation for Anesthesia Induction
      Dong Dong, Xuemei Peng, Jie Liu, Hao Qian, Jiayang Li and Baojian Wu
      Drug Metabolism and Disposition October 2016, 44 (10) 1579-1583; DOI: https://doi.org/10.1124/dmd.116.071605

  7. Wynant, Inneke

    1. In Vitro and In Vivo Drug-Drug Interaction Studies to Assess the Effect of Abiraterone Acetate, Abiraterone, and Metabolites of Abiraterone on CYP2C8 Activity
      Johan Monbaliu, Martha Gonzalez, Apexa Bernard, James Jiao, Carlo Sensenhauser, Jan Snoeys, Hans Stieltjes, Inneke Wynant, Johan W. Smit and Caly Chien
      Drug Metabolism and Disposition October 2016, 44 (10) 1682-1691; DOI: https://doi.org/10.1124/dmd.116.070672

X

  1. Xu, Xin

    1. An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software
      Pranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin Xu
      Drug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017

  2. Xu, Yingchun

    1. Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular Carcinoma
      Xiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing Chen
      Drug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243

Y

  1. Yang, Xiaoqing

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  2. Yeleswaram, Swamy

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  3. Yoshikado, Takashi

    1. Clarification of the Mechanism of Clopidogrel-Mediated Drug–Drug Interaction in a Clinical Cassette Small-dose Study and Its Prediction Based on In Vitro Information
      Soo-Jin Kim, Takashi Yoshikado, Ichiro Ieiri, Kazuya Maeda, Miyuki Kimura, Shin Irie, Hiroyuki Kusuhara and Yuichi Sugiyama
      Drug Metabolism and Disposition October 2016, 44 (10) 1622-1632; DOI: https://doi.org/10.1124/dmd.116.070276

  4. Young-Sciame, Ruth

    1. Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans
      Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
      Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

  5. Yuasa, Hiroaki

    1. Characteristic Analysis of Intestinal Transport in Enterocyte-Like Cells Differentiated from Human Induced Pluripotent Stem Cells
      Nao Kodama, Takahiro Iwao, Takahiro Katano, Kinya Ohta, Hiroaki Yuasa and Tamihide Matsunaga
      Drug Metabolism and Disposition October 2016, 44 (10) 1662-1667; DOI: https://doi.org/10.1124/dmd.116.069336

Z

  1. Zakharov, Alexey

    1. An Automated High-Throughput Metabolic Stability Assay Using an Integrated High-Resolution Accurate Mass Method and Automated Data Analysis Software
      Pranav Shah, Edward Kerns, Dac-Trung Nguyen, R. Scott Obach, Amy Q. Wang, Alexey Zakharov, John McKew, Anton Simeonov, Cornelis E. C. A. Hop and Xin Xu
      Drug Metabolism and Disposition October 2016, 44 (10) 1653-1661; DOI: https://doi.org/10.1124/dmd.116.072017

  2. Zeng, Su

    1. Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular Carcinoma
      Xiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing Chen
      Drug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243

  3. Zhang, Jin

    1. Utilization of Stable Isotope Labeling to Facilitate the Identification of Polar Metabolites of KAF156, an Antimalarial Agent
      Su-Er W. Huskey, Ry R. Forseth, Hongmei Li, Zhigang Jian, Alexandre Catoire, Jin Zhang, Tapan Ray, Handan He, Jimmy Flarakos and James B. Mangold
      Drug Metabolism and Disposition October 2016, 44 (10) 1697-1708; DOI: https://doi.org/10.1124/dmd.116.072108
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