Research ArticleArticle
Methylation of the Constitutive Androstane Receptor Is Involved in the Suppression of CYP2C19 in Hepatitis B Virus–Associated Hepatocellular Carcinoma
Xiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing Chen
Drug Metabolism and Disposition October 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243
Xiaojing Tang
Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China (X.T., W.L., Y.X., S.Z., S.C.); Department of Pharmacy, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China (L.G.); and Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China (Z.C., S.K.)
Lele Ge
Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China (X.T., W.L., Y.X., S.Z., S.C.); Department of Pharmacy, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China (L.G.); and Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China (Z.C., S.K.)
Zhongjian Chen
Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China (X.T., W.L., Y.X., S.Z., S.C.); Department of Pharmacy, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China (L.G.); and Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China (Z.C., S.K.)
Sisi Kong
Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China (X.T., W.L., Y.X., S.Z., S.C.); Department of Pharmacy, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China (L.G.); and Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China (Z.C., S.K.)
Wenhui Liu
Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China (X.T., W.L., Y.X., S.Z., S.C.); Department of Pharmacy, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China (L.G.); and Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China (Z.C., S.K.)
Yingchun Xu
Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China (X.T., W.L., Y.X., S.Z., S.C.); Department of Pharmacy, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China (L.G.); and Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China (Z.C., S.K.)
Su Zeng
Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China (X.T., W.L., Y.X., S.Z., S.C.); Department of Pharmacy, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China (L.G.); and Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China (Z.C., S.K.)
Shuqing Chen
Institute of Drug Metabolism and Pharmaceutical Analysis, Zhejiang Province Key Laboratory of Anti-Cancer Drug Research, College of Pharmaceutical Sciences, Zhejiang University, Hangzhou, Zhejiang, China (X.T., W.L., Y.X., S.Z., S.C.); Department of Pharmacy, Sir Run Run Shaw Hospital, College of Medicine, Zhejiang University, Hangzhou, China (L.G.); and Department of Pharmacy, Zhejiang Cancer Hospital, Hangzhou, China (Z.C., S.K.)

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Research ArticleArticle
Epigenetic Study of CYP2C19 in Hepatocellular Carcinoma
Xiaojing Tang, Lele Ge, Zhongjian Chen, Sisi Kong, Wenhui Liu, Yingchun Xu, Su Zeng and Shuqing Chen
Drug Metabolism and Disposition October 1, 2016, 44 (10) 1643-1652; DOI: https://doi.org/10.1124/dmd.116.070243
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