Advertisement
Research ArticleArticle

Roles of UGT, P450, and Gut Microbiota in the Metabolism of Epacadostat in Humans

Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
Drug Metabolism and Disposition October 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680

Article Information

vol. 44 no. 10 1668-1674
DOI 
https://doi.org/10.1124/dmd.116.070680
PubMed 
27457784
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received March 31, 2016
  • Accepted July 20, 2016
  • Published online September 1, 2016.

Article Versions

Copyright & Usage 
Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Jason Boer,
  2. Ruth Young-Sciame,
  3. Fiona Lee,
  4. Kevin J. Bowman,
  5. Xiaoqing Yang,
  6. Jack G. Shi,
  7. Frank M. Nedza,
  8. William Frietze,
  9. Laurine Galya,
  10. Andrew P. Combs,
  11. Swamy Yeleswaram, and
  12. Sharon Diamond
  1. Incyte Corporation, Wilmington, Delaware
  1. Address correspondence to:
    Dr. Jason Boer, Incyte Corporation, 1801 Augustine Cut-Off, Wilmington, DE 19803. E-mail: jboer{at}incyte.com
View Full Text

Statistics from Altmetric.com

Article usage

Article usage: August 2017 to March 2023

AbstractFullPdf
Aug 2017732531
Sep 2017365236
Oct 2017215641
Nov 2017196771
Dec 2017115641
Jan 2018197740
Feb 2018105729
Mar 201837559
Apr 201837937
May 201878766
Jun 201844122
Jul 201843015
Aug 201863219
Sep 201842218
Oct 2018103521
Nov 201862820
Dec 201844812
Jan 20194429
Feb 201972814
Mar 201951517
Apr 201961821
May 201922922
Jun 201922030
Jul 201953327
Aug 201931910
Oct 201952924
Nov 201972420
Dec 201952422
Jan 202034519
Feb 202002314
Mar 202032812
May 202042218
Jun 202075431
Jul 202054128
Aug 202042547
Sep 202063027
Oct 2020113725
Nov 202082814
Dec 2020101916
Jan 202153121
Feb 202191412
Mar 202161714
Apr 20215199
May 202182413
Jun 20219289
Jul 2021111618
Aug 202191519
Sep 202122922
Oct 202143738
Nov 202153533
Dec 20212266
Jan 202251710
Feb 2022111914
Mar 202273617
Apr 202264319
May 202253333
Jun 20222317
Jul 202262118
Aug 202213618
Sep 202295158
Oct 20225961
Nov 202241610
Dec 20222356
Jan 20235845
Feb 20234561
Mar 20232830

Back to top

In this issue

Download PDF
Article Alerts
Email Article
Citation Tools

Research ArticleArticle

Metabolism of Epacadostat in Humans

Jason Boer, Ruth Young-Sciame, Fiona Lee, Kevin J. Bowman, Xiaoqing Yang, Jack G. Shi, Frank M. Nedza, William Frietze, Laurine Galya, Andrew P. Combs, Swamy Yeleswaram and Sharon Diamond
Drug Metabolism and Disposition October 1, 2016, 44 (10) 1668-1674; DOI: https://doi.org/10.1124/dmd.116.070680
Reddit logo Twitter logo Facebook logo Mendeley logo

Jump to section

Advertisement