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Index by author

December 01, 2016; Volume 44,Issue 12

A

  1. Afshari, Cynthia

    1. Modeling Therapeutic Antibody–Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform
      Thomas J. Long, Patrick A. Cosgrove, Robert T. Dunn, Donna B. Stolz, Hisham Hamadeh, Cynthia Afshari, Helen McBride and Linda G. Griffith
      Drug Metabolism and Disposition December 2016, 44 (12) 1940-1948; DOI: https://doi.org/10.1124/dmd.116.071456

  2. Alicke, Bruno

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

B

  1. Backes, Wayne L.

    1. Cytochrome P450 Organization and Function Are Modulated by Endoplasmic Reticulum Phospholipid Heterogeneity
      Lauren M. Brignac-Huber, Ji Won Park, James R. Reed and Wayne L. Backes
      Drug Metabolism and Disposition December 2016, 44 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.115.068981

  2. Bando, Toru

    1. Pharmacokinetics and Differential Regulation of Cytochrome P450 Enzymes in Type 1 Allergic Mice
      Tadatoshi Tanino, Akira Komada, Koji Ueda, Toru Bando, Yukie Nojiri, Yukari Ueda and Eiichi Sakurai
      Drug Metabolism and Disposition December 2016, 44 (12) 1950-1957; DOI: https://doi.org/10.1124/dmd.116.072462

  3. Benoit, Etienne

    1. Development of an Ecofriendly Anticoagulant Rodenticide Based on the Stereochemistry of Difenacoum
      Marlène Damin-Pernik, Bernadette Espana, Stéphane Besse, Isabelle Fourel, Hervé Caruel, Florence Popowycz, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition December 2016, 44 (12) 1872-1880; DOI: https://doi.org/10.1124/dmd.116.071688

  4. Benoit-Biancamano, Marie-Odile

    1. A Rare UGT2B7 Variant Creates a Novel N-Glycosylation Site at Codon 121 with Impaired Enzyme Activity
      Camille Girard-Bock, Marie-Odile Benoit-Biancamano, Lyne Villeneuve, Sylvie Desjardins and Chantal Guillemette
      Drug Metabolism and Disposition December 2016, 44 (12) 1867-1871; DOI: https://doi.org/10.1124/dmd.116.071860

  5. Besse, Stéphane

    1. Development of an Ecofriendly Anticoagulant Rodenticide Based on the Stereochemistry of Difenacoum
      Marlène Damin-Pernik, Bernadette Espana, Stéphane Besse, Isabelle Fourel, Hervé Caruel, Florence Popowycz, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition December 2016, 44 (12) 1872-1880; DOI: https://doi.org/10.1124/dmd.116.071688

  6. Billington, Sarah

    1. Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
      Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W. Chung, Colin D.A. Brown, Edward J. Kelly, Jonathan Himmelfarb and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2016, 44 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.116.072066

  7. Brignac-Huber, Lauren M.

    1. Cytochrome P450 Organization and Function Are Modulated by Endoplasmic Reticulum Phospholipid Heterogeneity
      Lauren M. Brignac-Huber, Ji Won Park, James R. Reed and Wayne L. Backes
      Drug Metabolism and Disposition December 2016, 44 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.115.068981

  8. Brown, Colin D.A.

    1. Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
      Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W. Chung, Colin D.A. Brown, Edward J. Kelly, Jonathan Himmelfarb and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2016, 44 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.116.072066

C

  1. Cao, Tim

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  2. Carano, Richard A.

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  3. Caruel, Hervé

    1. Development of an Ecofriendly Anticoagulant Rodenticide Based on the Stereochemistry of Difenacoum
      Marlène Damin-Pernik, Bernadette Espana, Stéphane Besse, Isabelle Fourel, Hervé Caruel, Florence Popowycz, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition December 2016, 44 (12) 1872-1880; DOI: https://doi.org/10.1124/dmd.116.071688

  4. Cheong, Jonathan

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  5. Chothe, Paresh P.

    1. Evaluation of the Interplay between Uptake Transport and CYP3A4 Induction in Micropatterned Cocultured Hepatocytes
      Amanda Moore, Paresh P. Chothe, Hong Tsao and Niresh Hariparsad
      Drug Metabolism and Disposition December 2016, 44 (12) 1910-1919; DOI: https://doi.org/10.1124/dmd.116.072660

  6. Chung, Git W.

    1. Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
      Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W. Chung, Colin D.A. Brown, Edward J. Kelly, Jonathan Himmelfarb and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2016, 44 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.116.072066

  7. Cosgrove, Patrick A.

    1. Modeling Therapeutic Antibody–Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform
      Thomas J. Long, Patrick A. Cosgrove, Robert T. Dunn, Donna B. Stolz, Hisham Hamadeh, Cynthia Afshari, Helen McBride and Linda G. Griffith
      Drug Metabolism and Disposition December 2016, 44 (12) 1940-1948; DOI: https://doi.org/10.1124/dmd.116.071456

  8. Court, Michael H.

    1. Tramadol Metabolism to O-Desmethyl Tramadol (M1) and N-Desmethyl Tramadol (M2) by Dog Liver Microsomes: Species Comparison and Identification of Responsible Canine Cytochrome P450s
      Tania E. Perez, Katrina L. Mealey, Tamara L. Grubb, Stephen A. Greene and Michael H. Court
      Drug Metabolism and Disposition December 2016, 44 (12) 1963-1972; DOI: https://doi.org/10.1124/dmd.116.071902

D

  1. Damin-Pernik, Marlène

    1. Development of an Ecofriendly Anticoagulant Rodenticide Based on the Stereochemistry of Difenacoum
      Marlène Damin-Pernik, Bernadette Espana, Stéphane Besse, Isabelle Fourel, Hervé Caruel, Florence Popowycz, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition December 2016, 44 (12) 1872-1880; DOI: https://doi.org/10.1124/dmd.116.071688

  2. Desjardins, Sylvie

    1. A Rare UGT2B7 Variant Creates a Novel N-Glycosylation Site at Codon 121 with Impaired Enzyme Activity
      Camille Girard-Bock, Marie-Odile Benoit-Biancamano, Lyne Villeneuve, Sylvie Desjardins and Chantal Guillemette
      Drug Metabolism and Disposition December 2016, 44 (12) 1867-1871; DOI: https://doi.org/10.1124/dmd.116.071860

  3. Dragovich, Peter S.

    1. Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice
      Yong Ma, S. Cyrus Khojasteh, Cornelis E.C.A. Hop, Hans K. Erickson, Andrew Polson, Thomas H. Pillow, Shang-Fan Yu, Hong Wang, Peter S. Dragovich and Donglu Zhang
      Drug Metabolism and Disposition December 2016, 44 (12) 1958-1962; DOI: https://doi.org/10.1124/dmd.116.073031

  4. Dunn, Robert T.

    1. Modeling Therapeutic Antibody–Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform
      Thomas J. Long, Patrick A. Cosgrove, Robert T. Dunn, Donna B. Stolz, Hisham Hamadeh, Cynthia Afshari, Helen McBride and Linda G. Griffith
      Drug Metabolism and Disposition December 2016, 44 (12) 1940-1948; DOI: https://doi.org/10.1124/dmd.116.071456

E

  1. Erickson, Hans K.

    1. Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice
      Yong Ma, S. Cyrus Khojasteh, Cornelis E.C.A. Hop, Hans K. Erickson, Andrew Polson, Thomas H. Pillow, Shang-Fan Yu, Hong Wang, Peter S. Dragovich and Donglu Zhang
      Drug Metabolism and Disposition December 2016, 44 (12) 1958-1962; DOI: https://doi.org/10.1124/dmd.116.073031

  2. Espana, Bernadette

    1. Development of an Ecofriendly Anticoagulant Rodenticide Based on the Stereochemistry of Difenacoum
      Marlène Damin-Pernik, Bernadette Espana, Stéphane Besse, Isabelle Fourel, Hervé Caruel, Florence Popowycz, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition December 2016, 44 (12) 1872-1880; DOI: https://doi.org/10.1124/dmd.116.071688

F

  1. Fourel, Isabelle

    1. Development of an Ecofriendly Anticoagulant Rodenticide Based on the Stereochemistry of Difenacoum
      Marlène Damin-Pernik, Bernadette Espana, Stéphane Besse, Isabelle Fourel, Hervé Caruel, Florence Popowycz, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition December 2016, 44 (12) 1872-1880; DOI: https://doi.org/10.1124/dmd.116.071688

G

  1. Girard-Bock, Camille

    1. A Rare UGT2B7 Variant Creates a Novel N-Glycosylation Site at Codon 121 with Impaired Enzyme Activity
      Camille Girard-Bock, Marie-Odile Benoit-Biancamano, Lyne Villeneuve, Sylvie Desjardins and Chantal Guillemette
      Drug Metabolism and Disposition December 2016, 44 (12) 1867-1871; DOI: https://doi.org/10.1124/dmd.116.071860

  2. Gould, Stephen E.

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  3. Greene, Stephen A.

    1. Tramadol Metabolism to O-Desmethyl Tramadol (M1) and N-Desmethyl Tramadol (M2) by Dog Liver Microsomes: Species Comparison and Identification of Responsible Canine Cytochrome P450s
      Tania E. Perez, Katrina L. Mealey, Tamara L. Grubb, Stephen A. Greene and Michael H. Court
      Drug Metabolism and Disposition December 2016, 44 (12) 1963-1972; DOI: https://doi.org/10.1124/dmd.116.071902

  4. Greve, Joan

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  5. Griffith, Linda G.

    1. Modeling Therapeutic Antibody–Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform
      Thomas J. Long, Patrick A. Cosgrove, Robert T. Dunn, Donna B. Stolz, Hisham Hamadeh, Cynthia Afshari, Helen McBride and Linda G. Griffith
      Drug Metabolism and Disposition December 2016, 44 (12) 1940-1948; DOI: https://doi.org/10.1124/dmd.116.071456

  6. Grubb, Tamara L.

    1. Tramadol Metabolism to O-Desmethyl Tramadol (M1) and N-Desmethyl Tramadol (M2) by Dog Liver Microsomes: Species Comparison and Identification of Responsible Canine Cytochrome P450s
      Tania E. Perez, Katrina L. Mealey, Tamara L. Grubb, Stephen A. Greene and Michael H. Court
      Drug Metabolism and Disposition December 2016, 44 (12) 1963-1972; DOI: https://doi.org/10.1124/dmd.116.071902

  7. Guengerich, F. Peter

    1. Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Tsutomu Shimada, Kensaku Kakimoto, Shigeo Takenaka, Nobuyuki Koga, Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki, Donghak Kim, F. Peter Guengerich and Masayuki Komori
      Drug Metabolism and Disposition December 2016, 44 (12) 1899-1909; DOI: https://doi.org/10.1124/dmd.116.072991

  8. Guillemette, Chantal

    1. A Rare UGT2B7 Variant Creates a Novel N-Glycosylation Site at Codon 121 with Impaired Enzyme Activity
      Camille Girard-Bock, Marie-Odile Benoit-Biancamano, Lyne Villeneuve, Sylvie Desjardins and Chantal Guillemette
      Drug Metabolism and Disposition December 2016, 44 (12) 1867-1871; DOI: https://doi.org/10.1124/dmd.116.071860

H

  1. Hamadeh, Hisham

    1. Modeling Therapeutic Antibody–Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform
      Thomas J. Long, Patrick A. Cosgrove, Robert T. Dunn, Donna B. Stolz, Hisham Hamadeh, Cynthia Afshari, Helen McBride and Linda G. Griffith
      Drug Metabolism and Disposition December 2016, 44 (12) 1940-1948; DOI: https://doi.org/10.1124/dmd.116.071456

  2. Hariparsad, Niresh

    1. Evaluation of the Interplay between Uptake Transport and CYP3A4 Induction in Micropatterned Cocultured Hepatocytes
      Amanda Moore, Paresh P. Chothe, Hong Tsao and Niresh Hariparsad
      Drug Metabolism and Disposition December 2016, 44 (12) 1910-1919; DOI: https://doi.org/10.1124/dmd.116.072660

  3. Heffron, Timothy P.

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  4. Himmelfarb, Jonathan

    1. Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
      Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W. Chung, Colin D.A. Brown, Edward J. Kelly, Jonathan Himmelfarb and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2016, 44 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.116.072066

  5. Hop, Cornelis E.C.A.

    1. Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice
      Yong Ma, S. Cyrus Khojasteh, Cornelis E.C.A. Hop, Hans K. Erickson, Andrew Polson, Thomas H. Pillow, Shang-Fan Yu, Hong Wang, Peter S. Dragovich and Donglu Zhang
      Drug Metabolism and Disposition December 2016, 44 (12) 1958-1962; DOI: https://doi.org/10.1124/dmd.116.073031

I

  1. Imai, Teruko

    1. Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine
      Kayoko Ohura, Hikaru Nishiyama, Saori Saco, Keisuke Kurokawa and Teruko Imai
      Drug Metabolism and Disposition December 2016, 44 (12) 1890-1898; DOI: https://doi.org/10.1124/dmd.116.072736

  2. Imamura, Yuichiro

    1. Investigation of Endogenous Compounds Applicable to Drug–Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans
      Yuri Tsuruya, Koji Kato, Yamato Sano, Yuichiro Imamura, Kazuya Maeda, Yuji Kumagai, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition December 2016, 44 (12) 1925-1933; DOI: https://doi.org/10.1124/dmd.116.071472

J

  1. Johnson, Katherine

    1. Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
      Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W. Chung, Colin D.A. Brown, Edward J. Kelly, Jonathan Himmelfarb and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2016, 44 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.116.072066

K

  1. Kakimoto, Kensaku

    1. Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Tsutomu Shimada, Kensaku Kakimoto, Shigeo Takenaka, Nobuyuki Koga, Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki, Donghak Kim, F. Peter Guengerich and Masayuki Komori
      Drug Metabolism and Disposition December 2016, 44 (12) 1899-1909; DOI: https://doi.org/10.1124/dmd.116.072991

  2. Kato, Koji

    1. Investigation of Endogenous Compounds Applicable to Drug–Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans
      Yuri Tsuruya, Koji Kato, Yamato Sano, Yuichiro Imamura, Kazuya Maeda, Yuji Kumagai, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition December 2016, 44 (12) 1925-1933; DOI: https://doi.org/10.1124/dmd.116.071472

  3. Kelly, Edward J.

    1. Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
      Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W. Chung, Colin D.A. Brown, Edward J. Kelly, Jonathan Himmelfarb and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2016, 44 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.116.072066

  4. Khojasteh, S. Cyrus

    1. Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice
      Yong Ma, S. Cyrus Khojasteh, Cornelis E.C.A. Hop, Hans K. Erickson, Andrew Polson, Thomas H. Pillow, Shang-Fan Yu, Hong Wang, Peter S. Dragovich and Donglu Zhang
      Drug Metabolism and Disposition December 2016, 44 (12) 1958-1962; DOI: https://doi.org/10.1124/dmd.116.073031

  5. Kim, Donghak

    1. Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Tsutomu Shimada, Kensaku Kakimoto, Shigeo Takenaka, Nobuyuki Koga, Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki, Donghak Kim, F. Peter Guengerich and Masayuki Komori
      Drug Metabolism and Disposition December 2016, 44 (12) 1899-1909; DOI: https://doi.org/10.1124/dmd.116.072991

  6. Koeppen, Hartmut

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  7. Koga, Nobuyuki

    1. Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Tsutomu Shimada, Kensaku Kakimoto, Shigeo Takenaka, Nobuyuki Koga, Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki, Donghak Kim, F. Peter Guengerich and Masayuki Komori
      Drug Metabolism and Disposition December 2016, 44 (12) 1899-1909; DOI: https://doi.org/10.1124/dmd.116.072991

  8. Komada, Akira

    1. Pharmacokinetics and Differential Regulation of Cytochrome P450 Enzymes in Type 1 Allergic Mice
      Tadatoshi Tanino, Akira Komada, Koji Ueda, Toru Bando, Yukie Nojiri, Yukari Ueda and Eiichi Sakurai
      Drug Metabolism and Disposition December 2016, 44 (12) 1950-1957; DOI: https://doi.org/10.1124/dmd.116.072462

  9. Komori, Masayuki

    1. Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Tsutomu Shimada, Kensaku Kakimoto, Shigeo Takenaka, Nobuyuki Koga, Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki, Donghak Kim, F. Peter Guengerich and Masayuki Komori
      Drug Metabolism and Disposition December 2016, 44 (12) 1899-1909; DOI: https://doi.org/10.1124/dmd.116.072991

  10. Kumagai, Yuji

    1. Investigation of Endogenous Compounds Applicable to Drug–Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans
      Yuri Tsuruya, Koji Kato, Yamato Sano, Yuichiro Imamura, Kazuya Maeda, Yuji Kumagai, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition December 2016, 44 (12) 1925-1933; DOI: https://doi.org/10.1124/dmd.116.071472

  11. Kurokawa, Keisuke

    1. Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine
      Kayoko Ohura, Hikaru Nishiyama, Saori Saco, Keisuke Kurokawa and Teruko Imai
      Drug Metabolism and Disposition December 2016, 44 (12) 1890-1898; DOI: https://doi.org/10.1124/dmd.116.072736

  12. Kusuhara, Hiroyuki

    1. Investigation of Endogenous Compounds Applicable to Drug–Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans
      Yuri Tsuruya, Koji Kato, Yamato Sano, Yuichiro Imamura, Kazuya Maeda, Yuji Kumagai, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition December 2016, 44 (12) 1925-1933; DOI: https://doi.org/10.1124/dmd.116.071472

L

  1. Lattard, Virginie

    1. Development of an Ecofriendly Anticoagulant Rodenticide Based on the Stereochemistry of Difenacoum
      Marlène Damin-Pernik, Bernadette Espana, Stéphane Besse, Isabelle Fourel, Hervé Caruel, Florence Popowycz, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition December 2016, 44 (12) 1872-1880; DOI: https://doi.org/10.1124/dmd.116.071688

  2. Lau, Shari

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  3. Lee, Caroline

    1. Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
      Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W. Chung, Colin D.A. Brown, Edward J. Kelly, Jonathan Himmelfarb and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2016, 44 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.116.072066

  4. Lee, Leslie B.

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  5. Long, Thomas J.

    1. Modeling Therapeutic Antibody–Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform
      Thomas J. Long, Patrick A. Cosgrove, Robert T. Dunn, Donna B. Stolz, Hisham Hamadeh, Cynthia Afshari, Helen McBride and Linda G. Griffith
      Drug Metabolism and Disposition December 2016, 44 (12) 1940-1948; DOI: https://doi.org/10.1124/dmd.116.071456

M

  1. Ma, Yong

    1. Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice
      Yong Ma, S. Cyrus Khojasteh, Cornelis E.C.A. Hop, Hans K. Erickson, Andrew Polson, Thomas H. Pillow, Shang-Fan Yu, Hong Wang, Peter S. Dragovich and Donglu Zhang
      Drug Metabolism and Disposition December 2016, 44 (12) 1958-1962; DOI: https://doi.org/10.1124/dmd.116.073031

  2. Maeda, Kazuya

    1. Investigation of Endogenous Compounds Applicable to Drug–Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans
      Yuri Tsuruya, Koji Kato, Yamato Sano, Yuichiro Imamura, Kazuya Maeda, Yuji Kumagai, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition December 2016, 44 (12) 1925-1933; DOI: https://doi.org/10.1124/dmd.116.071472

  3. Martinez, Marilyn N.

    1. When Is It Important to Measure Unbound Drug in Evaluating Nanomedicine Pharmacokinetics?
      Stephan T. Stern, Marilyn N. Martinez and David M. Stevens
      Drug Metabolism and Disposition December 2016, 44 (12) 1934-1939; DOI: https://doi.org/10.1124/dmd.116.073148

  4. McBride, Helen

    1. Modeling Therapeutic Antibody–Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform
      Thomas J. Long, Patrick A. Cosgrove, Robert T. Dunn, Donna B. Stolz, Hisham Hamadeh, Cynthia Afshari, Helen McBride and Linda G. Griffith
      Drug Metabolism and Disposition December 2016, 44 (12) 1940-1948; DOI: https://doi.org/10.1124/dmd.116.071456

  5. Mealey, Katrina L.

    1. Tramadol Metabolism to O-Desmethyl Tramadol (M1) and N-Desmethyl Tramadol (M2) by Dog Liver Microsomes: Species Comparison and Identification of Responsible Canine Cytochrome P450s
      Tania E. Perez, Katrina L. Mealey, Tamara L. Grubb, Stephen A. Greene and Michael H. Court
      Drug Metabolism and Disposition December 2016, 44 (12) 1963-1972; DOI: https://doi.org/10.1124/dmd.116.071902

  6. Moore, Amanda

    1. Evaluation of the Interplay between Uptake Transport and CYP3A4 Induction in Micropatterned Cocultured Hepatocytes
      Amanda Moore, Paresh P. Chothe, Hong Tsao and Niresh Hariparsad
      Drug Metabolism and Disposition December 2016, 44 (12) 1910-1919; DOI: https://doi.org/10.1124/dmd.116.072660

  7. Murayama, Norie

    1. Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Tsutomu Shimada, Kensaku Kakimoto, Shigeo Takenaka, Nobuyuki Koga, Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki, Donghak Kim, F. Peter Guengerich and Masayuki Komori
      Drug Metabolism and Disposition December 2016, 44 (12) 1899-1909; DOI: https://doi.org/10.1124/dmd.116.072991

N

  1. Nannini-Pepe, Michelle

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  2. Nishimura, Merry

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  3. Nishiyama, Hikaru

    1. Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine
      Kayoko Ohura, Hikaru Nishiyama, Saori Saco, Keisuke Kurokawa and Teruko Imai
      Drug Metabolism and Disposition December 2016, 44 (12) 1890-1898; DOI: https://doi.org/10.1124/dmd.116.072736

  4. Nojiri, Yukie

    1. Pharmacokinetics and Differential Regulation of Cytochrome P450 Enzymes in Type 1 Allergic Mice
      Tadatoshi Tanino, Akira Komada, Koji Ueda, Toru Bando, Yukie Nojiri, Yukari Ueda and Eiichi Sakurai
      Drug Metabolism and Disposition December 2016, 44 (12) 1950-1957; DOI: https://doi.org/10.1124/dmd.116.072462

O

  1. Ohura, Kayoko

    1. Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine
      Kayoko Ohura, Hikaru Nishiyama, Saori Saco, Keisuke Kurokawa and Teruko Imai
      Drug Metabolism and Disposition December 2016, 44 (12) 1890-1898; DOI: https://doi.org/10.1124/dmd.116.072736

  2. Olivero, Alan G.

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

P

  1. Pang, Jodie

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  2. Park, Ji Won

    1. Cytochrome P450 Organization and Function Are Modulated by Endoplasmic Reticulum Phospholipid Heterogeneity
      Lauren M. Brignac-Huber, Ji Won Park, James R. Reed and Wayne L. Backes
      Drug Metabolism and Disposition December 2016, 44 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.115.068981

  3. Perez, Tania E.

    1. Tramadol Metabolism to O-Desmethyl Tramadol (M1) and N-Desmethyl Tramadol (M2) by Dog Liver Microsomes: Species Comparison and Identification of Responsible Canine Cytochrome P450s
      Tania E. Perez, Katrina L. Mealey, Tamara L. Grubb, Stephen A. Greene and Michael H. Court
      Drug Metabolism and Disposition December 2016, 44 (12) 1963-1972; DOI: https://doi.org/10.1124/dmd.116.071902

  4. Phillips, Heidi S.

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  5. Pillow, Thomas H.

    1. Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice
      Yong Ma, S. Cyrus Khojasteh, Cornelis E.C.A. Hop, Hans K. Erickson, Andrew Polson, Thomas H. Pillow, Shang-Fan Yu, Hong Wang, Peter S. Dragovich and Donglu Zhang
      Drug Metabolism and Disposition December 2016, 44 (12) 1958-1962; DOI: https://doi.org/10.1124/dmd.116.073031

  6. Plise, Emile G.

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  7. Polson, Andrew

    1. Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice
      Yong Ma, S. Cyrus Khojasteh, Cornelis E.C.A. Hop, Hans K. Erickson, Andrew Polson, Thomas H. Pillow, Shang-Fan Yu, Hong Wang, Peter S. Dragovich and Donglu Zhang
      Drug Metabolism and Disposition December 2016, 44 (12) 1958-1962; DOI: https://doi.org/10.1124/dmd.116.073031

  8. Popowycz, Florence

    1. Development of an Ecofriendly Anticoagulant Rodenticide Based on the Stereochemistry of Difenacoum
      Marlène Damin-Pernik, Bernadette Espana, Stéphane Besse, Isabelle Fourel, Hervé Caruel, Florence Popowycz, Etienne Benoit and Virginie Lattard
      Drug Metabolism and Disposition December 2016, 44 (12) 1872-1880; DOI: https://doi.org/10.1124/dmd.116.071688

  9. Prasad, Bhagwat

    1. Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
      Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W. Chung, Colin D.A. Brown, Edward J. Kelly, Jonathan Himmelfarb and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2016, 44 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.116.072066

Q

  1. Quiason, Cristine

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

R

  1. Rangell, Linda

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  2. Reed, James R.

    1. Cytochrome P450 Organization and Function Are Modulated by Endoplasmic Reticulum Phospholipid Heterogeneity
      Lauren M. Brignac-Huber, Ji Won Park, James R. Reed and Wayne L. Backes
      Drug Metabolism and Disposition December 2016, 44 (12) 1859-1866; DOI: https://doi.org/10.1124/dmd.115.068981

S

  1. Saco, Saori

    1. Establishment and Characterization of a Novel Caco-2 Subclone with a Similar Low Expression Level of Human Carboxylesterase 1 to Human Small Intestine
      Kayoko Ohura, Hikaru Nishiyama, Saori Saco, Keisuke Kurokawa and Teruko Imai
      Drug Metabolism and Disposition December 2016, 44 (12) 1890-1898; DOI: https://doi.org/10.1124/dmd.116.072736

  2. Sakurai, Eiichi

    1. Pharmacokinetics and Differential Regulation of Cytochrome P450 Enzymes in Type 1 Allergic Mice
      Tadatoshi Tanino, Akira Komada, Koji Ueda, Toru Bando, Yukie Nojiri, Yukari Ueda and Eiichi Sakurai
      Drug Metabolism and Disposition December 2016, 44 (12) 1950-1957; DOI: https://doi.org/10.1124/dmd.116.072462

  3. Salphati, Laurent

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  4. Sano, Yamato

    1. Investigation of Endogenous Compounds Applicable to Drug–Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans
      Yuri Tsuruya, Koji Kato, Yamato Sano, Yuichiro Imamura, Kazuya Maeda, Yuji Kumagai, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition December 2016, 44 (12) 1925-1933; DOI: https://doi.org/10.1124/dmd.116.071472

  5. Shahidi-Latham, Sheerin

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423

  6. Shimada, Tsutomu

    1. Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Tsutomu Shimada, Kensaku Kakimoto, Shigeo Takenaka, Nobuyuki Koga, Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki, Donghak Kim, F. Peter Guengerich and Masayuki Komori
      Drug Metabolism and Disposition December 2016, 44 (12) 1899-1909; DOI: https://doi.org/10.1124/dmd.116.072991

  7. Stern, Stephan T.

    1. When Is It Important to Measure Unbound Drug in Evaluating Nanomedicine Pharmacokinetics?
      Stephan T. Stern, Marilyn N. Martinez and David M. Stevens
      Drug Metabolism and Disposition December 2016, 44 (12) 1934-1939; DOI: https://doi.org/10.1124/dmd.116.073148

  8. Stevens, David M.

    1. When Is It Important to Measure Unbound Drug in Evaluating Nanomedicine Pharmacokinetics?
      Stephan T. Stern, Marilyn N. Martinez and David M. Stevens
      Drug Metabolism and Disposition December 2016, 44 (12) 1934-1939; DOI: https://doi.org/10.1124/dmd.116.073148

  9. Stolz, Donna B.

    1. Modeling Therapeutic Antibody–Small Molecule Drug-Drug Interactions Using a Three-Dimensional Perfusable Human Liver Coculture Platform
      Thomas J. Long, Patrick A. Cosgrove, Robert T. Dunn, Donna B. Stolz, Hisham Hamadeh, Cynthia Afshari, Helen McBride and Linda G. Griffith
      Drug Metabolism and Disposition December 2016, 44 (12) 1940-1948; DOI: https://doi.org/10.1124/dmd.116.071456

  10. Sugiyama, Yuichi

    1. Investigation of Endogenous Compounds Applicable to Drug–Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans
      Yuri Tsuruya, Koji Kato, Yamato Sano, Yuichiro Imamura, Kazuya Maeda, Yuji Kumagai, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition December 2016, 44 (12) 1925-1933; DOI: https://doi.org/10.1124/dmd.116.071472

T

  1. Takenaka, Shigeo

    1. Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Tsutomu Shimada, Kensaku Kakimoto, Shigeo Takenaka, Nobuyuki Koga, Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki, Donghak Kim, F. Peter Guengerich and Masayuki Komori
      Drug Metabolism and Disposition December 2016, 44 (12) 1899-1909; DOI: https://doi.org/10.1124/dmd.116.072991

  2. Tanino, Tadatoshi

    1. Pharmacokinetics and Differential Regulation of Cytochrome P450 Enzymes in Type 1 Allergic Mice
      Tadatoshi Tanino, Akira Komada, Koji Ueda, Toru Bando, Yukie Nojiri, Yukari Ueda and Eiichi Sakurai
      Drug Metabolism and Disposition December 2016, 44 (12) 1950-1957; DOI: https://doi.org/10.1124/dmd.116.072462

  3. Tsao, Hong

    1. Evaluation of the Interplay between Uptake Transport and CYP3A4 Induction in Micropatterned Cocultured Hepatocytes
      Amanda Moore, Paresh P. Chothe, Hong Tsao and Niresh Hariparsad
      Drug Metabolism and Disposition December 2016, 44 (12) 1910-1919; DOI: https://doi.org/10.1124/dmd.116.072660

  4. Tsuruya, Yuri

    1. Investigation of Endogenous Compounds Applicable to Drug–Drug Interaction Studies Involving the Renal Organic Anion Transporters, OAT1 and OAT3, in Humans
      Yuri Tsuruya, Koji Kato, Yamato Sano, Yuichiro Imamura, Kazuya Maeda, Yuji Kumagai, Yuichi Sugiyama and Hiroyuki Kusuhara
      Drug Metabolism and Disposition December 2016, 44 (12) 1925-1933; DOI: https://doi.org/10.1124/dmd.116.071472

U

  1. Ueda, Koji

    1. Pharmacokinetics and Differential Regulation of Cytochrome P450 Enzymes in Type 1 Allergic Mice
      Tadatoshi Tanino, Akira Komada, Koji Ueda, Toru Bando, Yukie Nojiri, Yukari Ueda and Eiichi Sakurai
      Drug Metabolism and Disposition December 2016, 44 (12) 1950-1957; DOI: https://doi.org/10.1124/dmd.116.072462

  2. Ueda, Yukari

    1. Pharmacokinetics and Differential Regulation of Cytochrome P450 Enzymes in Type 1 Allergic Mice
      Tadatoshi Tanino, Akira Komada, Koji Ueda, Toru Bando, Yukie Nojiri, Yukari Ueda and Eiichi Sakurai
      Drug Metabolism and Disposition December 2016, 44 (12) 1950-1957; DOI: https://doi.org/10.1124/dmd.116.072462

  3. Uehara, Shotaro

    1. Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Tsutomu Shimada, Kensaku Kakimoto, Shigeo Takenaka, Nobuyuki Koga, Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki, Donghak Kim, F. Peter Guengerich and Masayuki Komori
      Drug Metabolism and Disposition December 2016, 44 (12) 1899-1909; DOI: https://doi.org/10.1124/dmd.116.072991

  4. Unadkat, Jashvant D.

    1. Abundance of Drug Transporters in the Human Kidney Cortex as Quantified by Quantitative Targeted Proteomics
      Bhagwat Prasad, Katherine Johnson, Sarah Billington, Caroline Lee, Git W. Chung, Colin D.A. Brown, Edward J. Kelly, Jonathan Himmelfarb and Jashvant D. Unadkat
      Drug Metabolism and Disposition December 2016, 44 (12) 1920-1924; DOI: https://doi.org/10.1124/dmd.116.072066

V

  1. Villeneuve, Lyne

    1. A Rare UGT2B7 Variant Creates a Novel N-Glycosylation Site at Codon 121 with Impaired Enzyme Activity
      Camille Girard-Bock, Marie-Odile Benoit-Biancamano, Lyne Villeneuve, Sylvie Desjardins and Chantal Guillemette
      Drug Metabolism and Disposition December 2016, 44 (12) 1867-1871; DOI: https://doi.org/10.1124/dmd.116.071860

W

  1. Wang, Hong

    1. Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice
      Yong Ma, S. Cyrus Khojasteh, Cornelis E.C.A. Hop, Hans K. Erickson, Andrew Polson, Thomas H. Pillow, Shang-Fan Yu, Hong Wang, Peter S. Dragovich and Donglu Zhang
      Drug Metabolism and Disposition December 2016, 44 (12) 1958-1962; DOI: https://doi.org/10.1124/dmd.116.073031

Y

  1. Yamazaki, Hiroshi

    1. Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Roles of Human CYP2A6 and Monkey CYP2A24 and 2A26 Cytochrome P450 Enzymes in the Oxidation of 2,5,2′,5′-Tetrachlorobiphenyl
      Tsutomu Shimada, Kensaku Kakimoto, Shigeo Takenaka, Nobuyuki Koga, Shotaro Uehara, Norie Murayama, Hiroshi Yamazaki, Donghak Kim, F. Peter Guengerich and Masayuki Komori
      Drug Metabolism and Disposition December 2016, 44 (12) 1899-1909; DOI: https://doi.org/10.1124/dmd.116.072991

  2. Yu, Shang-Fan

    1. Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice
      Yong Ma, S. Cyrus Khojasteh, Cornelis E.C.A. Hop, Hans K. Erickson, Andrew Polson, Thomas H. Pillow, Shang-Fan Yu, Hong Wang, Peter S. Dragovich and Donglu Zhang
      Drug Metabolism and Disposition December 2016, 44 (12) 1958-1962; DOI: https://doi.org/10.1124/dmd.116.073031

Z

  1. Zhang, Donglu

    1. Antibody Drug Conjugates Differentiate Uptake and DNA Alkylation of Pyrrolobenzodiazepines in Tumors from Organs of Xenograft Mice
      Yong Ma, S. Cyrus Khojasteh, Cornelis E.C.A. Hop, Hans K. Erickson, Andrew Polson, Thomas H. Pillow, Shang-Fan Yu, Hong Wang, Peter S. Dragovich and Donglu Zhang
      Drug Metabolism and Disposition December 2016, 44 (12) 1958-1962; DOI: https://doi.org/10.1124/dmd.116.073031

  2. Zhang, Xiaolin

    1. Brain Distribution and Efficacy of the Brain Penetrant PI3K Inhibitor GDC-0084 in Orthotopic Mouse Models of Human Glioblastoma
      Laurent Salphati, Bruno Alicke, Timothy P. Heffron, Sheerin Shahidi-Latham, Merry Nishimura, Tim Cao, Richard A. Carano, Jonathan Cheong, Joan Greve, Hartmut Koeppen, Shari Lau, Leslie B. Lee, Michelle Nannini-Pepe, Jodie Pang, Emile G. Plise, Cristine Quiason, Linda Rangell, Xiaolin Zhang, Stephen E. Gould, Heidi S. Phillips and Alan G. Olivero
      Drug Metabolism and Disposition December 2016, 44 (12) 1881-1889; DOI: https://doi.org/10.1124/dmd.116.071423
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