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Rapid CommunicationShort Communication

A Rare UGT2B7 Variant Creates a Novel N-Glycosylation Site at Codon 121 with Impaired Enzyme Activity

Camille Girard-Bock, Marie-Odile Benoit-Biancamano, Lyne Villeneuve, Sylvie Desjardins and Chantal Guillemette
Drug Metabolism and Disposition December 2016, 44 (12) 1867-1871; DOI: https://doi.org/10.1124/dmd.116.071860
Camille Girard-Bock
Pharmacogenomics Laboratory, Canada Research Chair in Pharmacogenomics, Centre Hospitalier Universitaire de Québec Research Center and Faculty of Pharmacy, Laval University, Québec City (C.G.B., L.V., S.D., C.G.), and Département de Pathologie et de Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, (M.O.B.B.), Québec, Canada
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Marie-Odile Benoit-Biancamano
Pharmacogenomics Laboratory, Canada Research Chair in Pharmacogenomics, Centre Hospitalier Universitaire de Québec Research Center and Faculty of Pharmacy, Laval University, Québec City (C.G.B., L.V., S.D., C.G.), and Département de Pathologie et de Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, (M.O.B.B.), Québec, Canada
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Lyne Villeneuve
Pharmacogenomics Laboratory, Canada Research Chair in Pharmacogenomics, Centre Hospitalier Universitaire de Québec Research Center and Faculty of Pharmacy, Laval University, Québec City (C.G.B., L.V., S.D., C.G.), and Département de Pathologie et de Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, (M.O.B.B.), Québec, Canada
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Sylvie Desjardins
Pharmacogenomics Laboratory, Canada Research Chair in Pharmacogenomics, Centre Hospitalier Universitaire de Québec Research Center and Faculty of Pharmacy, Laval University, Québec City (C.G.B., L.V., S.D., C.G.), and Département de Pathologie et de Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, (M.O.B.B.), Québec, Canada
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Chantal Guillemette
Pharmacogenomics Laboratory, Canada Research Chair in Pharmacogenomics, Centre Hospitalier Universitaire de Québec Research Center and Faculty of Pharmacy, Laval University, Québec City (C.G.B., L.V., S.D., C.G.), and Département de Pathologie et de Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, (M.O.B.B.), Québec, Canada
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Article Information

vol. 44 no. 12 1867-1871
DOI 
https://doi.org/10.1124/dmd.116.071860
PubMed 
27612916

Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received May 31, 2016
  • Accepted September 8, 2016
  • Published online October 25, 2016.

Article Versions

  • Earlier version (September 9, 2016 - 11:04).
  • Earlier version (September 12, 2016 - 10:26).
  • You are viewing the most recent version of this article.
Copyright & Usage 
Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Camille Girard-Bock,
  2. Marie-Odile Benoit-Biancamano,
  3. Lyne Villeneuve,
  4. Sylvie Desjardins, and
  5. Chantal Guillemette
  1. Pharmacogenomics Laboratory, Canada Research Chair in Pharmacogenomics, Centre Hospitalier Universitaire de Québec Research Center and Faculty of Pharmacy, Laval University, Québec City (C.G.B., L.V., S.D., C.G.), and Département de Pathologie et de Microbiologie, Faculté de Médecine Vétérinaire, Université de Montréal, Saint-Hyacinthe, (M.O.B.B.), Québec, Canada
  1. Address correspondence to:
    Dr. Chantal Guillemette, Canada Research Chair in Pharmacogenomics, Centre Hospitalier Universitaire de Québec Research Center, Room R4720, 2705 Boulevard Laurier, Québec City, QC, Canada, G1V 4G2. E-mail: Chantal.Guillemette{at}crchudequebec.ulaval.ca
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Drug Metabolism and Disposition: 44 (12)
Drug Metabolism and Disposition
Vol. 44, Issue 12
1 Dec 2016
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Rapid CommunicationShort Communication

A Rare Functional UGT2B7 D121N Variant

Camille Girard-Bock, Marie-Odile Benoit-Biancamano, Lyne Villeneuve, Sylvie Desjardins and Chantal Guillemette
Drug Metabolism and Disposition December 1, 2016, 44 (12) 1867-1871; DOI: https://doi.org/10.1124/dmd.116.071860

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Rapid CommunicationShort Communication

A Rare Functional UGT2B7 D121N Variant

Camille Girard-Bock, Marie-Odile Benoit-Biancamano, Lyne Villeneuve, Sylvie Desjardins and Chantal Guillemette
Drug Metabolism and Disposition December 1, 2016, 44 (12) 1867-1871; DOI: https://doi.org/10.1124/dmd.116.071860
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