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Drug Metabolism & Disposition

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    • Current Issue
    • Fast Forward
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Index by author

February 01, 2016; Volume 44,Issue 2
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Ambudkar, Suresh V.

    1. You have access
      Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers
      King Leung Fung, Khyati Kapoor, Jessica N. Pixley, Darrell J. Talbert, Alexandra D.T. Kwit, Suresh V. Ambudkar and Michael M. Gottesman
      Drug Metabolism and Disposition February 2016, 44 (2) 180-188; DOI: https://doi.org/10.1124/dmd.115.066506
  2. Avram, Michael J.

    1. Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      You have access
      Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      Dinelia Rivera-Burgos, Ujjal Sarkar, Amanda R. Lever, Michael J. Avram, Jonathan R. Coppeta, John S. Wishnok, Jeffrey T. Borenstein and Steven R. Tannenbaum
      Drug Metabolism and Disposition February 2016, 44 (2) 220-226; DOI: https://doi.org/10.1124/dmd.115.066365

B

  1. Ballard, T. Eric

    1. You have access
      Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism
      T. Eric Ballard, Shuai Wang, Loretta M. Cox, Mark A. Moen, Stacy Krzyzewski, Okechukwu Ukairo and R. Scott Obach
      Drug Metabolism and Disposition February 2016, 44 (2) 172-179; DOI: https://doi.org/10.1124/dmd.115.066688
  2. Bernhardt, Rita

    1. You have access
      Metabolism of Oral Turinabol by Human Steroid Hormone–Synthesizing Cytochrome P450 Enzymes
      Lina Schiffer, Simone Brixius-Anderko, Frank Hannemann, Josef Zapp, Jens Neunzig, Mario Thevis and Rita Bernhardt
      Drug Metabolism and Disposition February 2016, 44 (2) 227-237; DOI: https://doi.org/10.1124/dmd.115.066829
  3. Borenstein, Jeffrey T.

    1. Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      You have access
      Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      Dinelia Rivera-Burgos, Ujjal Sarkar, Amanda R. Lever, Michael J. Avram, Jonathan R. Coppeta, John S. Wishnok, Jeffrey T. Borenstein and Steven R. Tannenbaum
      Drug Metabolism and Disposition February 2016, 44 (2) 220-226; DOI: https://doi.org/10.1124/dmd.115.066365
  4. Brixius-Anderko, Simone

    1. You have access
      Metabolism of Oral Turinabol by Human Steroid Hormone–Synthesizing Cytochrome P450 Enzymes
      Lina Schiffer, Simone Brixius-Anderko, Frank Hannemann, Josef Zapp, Jens Neunzig, Mario Thevis and Rita Bernhardt
      Drug Metabolism and Disposition February 2016, 44 (2) 227-237; DOI: https://doi.org/10.1124/dmd.115.066829

C

  1. Cao, Yanguang

    1. You have access
      Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice
      Vidya Ramakrishnan, Qi Joy Yang, Holly P. Quach, Yanguang Cao, Edwin C. Y. Chow, Donald E. Mager and K. Sandy Pang
      Drug Metabolism and Disposition February 2016, 44 (2) 189-208; DOI: https://doi.org/10.1124/dmd.115.067033
  2. Chen, Cliff

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  3. Cheng, Sunny Lihua

    1. You have access
      Regulation of Hepatic Drug-Metabolizing Enzymes in Germ-Free Mice by Conventionalization and Probiotics
      Felcy Pavithra Selwyn, Sunny Lihua Cheng, Curtis D. Klaassen and Julia Yue Cui
      Drug Metabolism and Disposition February 2016, 44 (2) 262-274; DOI: https://doi.org/10.1124/dmd.115.067504
  4. Chow, Edwin C. Y.

    1. You have access
      Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice
      Vidya Ramakrishnan, Qi Joy Yang, Holly P. Quach, Yanguang Cao, Edwin C. Y. Chow, Donald E. Mager and K. Sandy Pang
      Drug Metabolism and Disposition February 2016, 44 (2) 189-208; DOI: https://doi.org/10.1124/dmd.115.067033
  5. Coppeta, Jonathan R.

    1. Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      You have access
      Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      Dinelia Rivera-Burgos, Ujjal Sarkar, Amanda R. Lever, Michael J. Avram, Jonathan R. Coppeta, John S. Wishnok, Jeffrey T. Borenstein and Steven R. Tannenbaum
      Drug Metabolism and Disposition February 2016, 44 (2) 220-226; DOI: https://doi.org/10.1124/dmd.115.066365
  6. Cox, Loretta M.

    1. You have access
      Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism
      T. Eric Ballard, Shuai Wang, Loretta M. Cox, Mark A. Moen, Stacy Krzyzewski, Okechukwu Ukairo and R. Scott Obach
      Drug Metabolism and Disposition February 2016, 44 (2) 172-179; DOI: https://doi.org/10.1124/dmd.115.066688
  7. Cui, Julia Yue

    1. You have access
      Regulation of Hepatic Drug-Metabolizing Enzymes in Germ-Free Mice by Conventionalization and Probiotics
      Felcy Pavithra Selwyn, Sunny Lihua Cheng, Curtis D. Klaassen and Julia Yue Cui
      Drug Metabolism and Disposition February 2016, 44 (2) 262-274; DOI: https://doi.org/10.1124/dmd.115.067504

D

  1. Di, Li

    1. You have access
      Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans
      Jennifer Q. Dong, Manthena V. Varma, Angela Wolford, Tim Ryder, Li Di, Bo Feng, Steven G. Terra, Kazuko Sagawa and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2016, 44 (2) 209-219; DOI: https://doi.org/10.1124/dmd.115.067868
  2. Dixit, Vaishali

    1. You have access
      Application of Micropatterned Cocultured Hepatocytes to Evaluate the Inductive Potential and Degradation Rate of Major Xenobiotic Metabolizing Enzymes
      Vaishali Dixit, Amanda Moore, Hong Tsao and Niresh Hariparsad
      Drug Metabolism and Disposition February 2016, 44 (2) 250-261; DOI: https://doi.org/10.1124/dmd.115.067173
  3. Dong, Jennifer Q.

    1. You have access
      Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans
      Jennifer Q. Dong, Manthena V. Varma, Angela Wolford, Tim Ryder, Li Di, Bo Feng, Steven G. Terra, Kazuko Sagawa and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2016, 44 (2) 209-219; DOI: https://doi.org/10.1124/dmd.115.067868

F

  1. Fancher, R. Marcus

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  2. Feng, Bo

    1. You have access
      Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans
      Jennifer Q. Dong, Manthena V. Varma, Angela Wolford, Tim Ryder, Li Di, Bo Feng, Steven G. Terra, Kazuko Sagawa and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2016, 44 (2) 209-219; DOI: https://doi.org/10.1124/dmd.115.067868
  3. Fung, King Leung

    1. You have access
      Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers
      King Leung Fung, Khyati Kapoor, Jessica N. Pixley, Darrell J. Talbert, Alexandra D.T. Kwit, Suresh V. Ambudkar and Michael M. Gottesman
      Drug Metabolism and Disposition February 2016, 44 (2) 180-188; DOI: https://doi.org/10.1124/dmd.115.066506
    2. You have access
      Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
      Lora D. Weidner, King Leung Fung, Pavitra Kannan, Janna K. Moen, Jeyan S. Kumar, Jan Mulder, Robert B. Innis, Michael M. Gottesman and Matthew D. Hall
      Drug Metabolism and Disposition February 2016, 44 (2) 275-282; DOI: https://doi.org/10.1124/dmd.115.067785

G

  1. Gottesman, Michael M.

    1. You have access
      Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers
      King Leung Fung, Khyati Kapoor, Jessica N. Pixley, Darrell J. Talbert, Alexandra D.T. Kwit, Suresh V. Ambudkar and Michael M. Gottesman
      Drug Metabolism and Disposition February 2016, 44 (2) 180-188; DOI: https://doi.org/10.1124/dmd.115.066506
    2. You have access
      Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
      Lora D. Weidner, King Leung Fung, Pavitra Kannan, Janna K. Moen, Jeyan S. Kumar, Jan Mulder, Robert B. Innis, Michael M. Gottesman and Matthew D. Hall
      Drug Metabolism and Disposition February 2016, 44 (2) 275-282; DOI: https://doi.org/10.1124/dmd.115.067785

H

  1. Hall, Matthew D.

    1. You have access
      Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
      Lora D. Weidner, King Leung Fung, Pavitra Kannan, Janna K. Moen, Jeyan S. Kumar, Jan Mulder, Robert B. Innis, Michael M. Gottesman and Matthew D. Hall
      Drug Metabolism and Disposition February 2016, 44 (2) 275-282; DOI: https://doi.org/10.1124/dmd.115.067785
  2. Hannemann, Frank

    1. You have access
      Metabolism of Oral Turinabol by Human Steroid Hormone–Synthesizing Cytochrome P450 Enzymes
      Lina Schiffer, Simone Brixius-Anderko, Frank Hannemann, Josef Zapp, Jens Neunzig, Mario Thevis and Rita Bernhardt
      Drug Metabolism and Disposition February 2016, 44 (2) 227-237; DOI: https://doi.org/10.1124/dmd.115.066829
  3. Hariparsad, Niresh

    1. You have access
      Application of Micropatterned Cocultured Hepatocytes to Evaluate the Inductive Potential and Degradation Rate of Major Xenobiotic Metabolizing Enzymes
      Vaishali Dixit, Amanda Moore, Hong Tsao and Niresh Hariparsad
      Drug Metabolism and Disposition February 2016, 44 (2) 250-261; DOI: https://doi.org/10.1124/dmd.115.067173

I

  1. Innis, Robert B.

    1. You have access
      Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
      Lora D. Weidner, King Leung Fung, Pavitra Kannan, Janna K. Moen, Jeyan S. Kumar, Jan Mulder, Robert B. Innis, Michael M. Gottesman and Matthew D. Hall
      Drug Metabolism and Disposition February 2016, 44 (2) 275-282; DOI: https://doi.org/10.1124/dmd.115.067785

J

  1. Jiang, Hao

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852

K

  1. Kalgutkar, Amit S.

    1. You have access
      Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans
      Jennifer Q. Dong, Manthena V. Varma, Angela Wolford, Tim Ryder, Li Di, Bo Feng, Steven G. Terra, Kazuko Sagawa and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2016, 44 (2) 209-219; DOI: https://doi.org/10.1124/dmd.115.067868
  2. Kandoussi, Hamza

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  3. Kannan, Pavitra

    1. You have access
      Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
      Lora D. Weidner, King Leung Fung, Pavitra Kannan, Janna K. Moen, Jeyan S. Kumar, Jan Mulder, Robert B. Innis, Michael M. Gottesman and Matthew D. Hall
      Drug Metabolism and Disposition February 2016, 44 (2) 275-282; DOI: https://doi.org/10.1124/dmd.115.067785
  4. Kapoor, Khyati

    1. You have access
      Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers
      King Leung Fung, Khyati Kapoor, Jessica N. Pixley, Darrell J. Talbert, Alexandra D.T. Kwit, Suresh V. Ambudkar and Michael M. Gottesman
      Drug Metabolism and Disposition February 2016, 44 (2) 180-188; DOI: https://doi.org/10.1124/dmd.115.066506
  5. Klaassen, Curtis D.

    1. You have access
      Regulation of Hepatic Drug-Metabolizing Enzymes in Germ-Free Mice by Conventionalization and Probiotics
      Felcy Pavithra Selwyn, Sunny Lihua Cheng, Curtis D. Klaassen and Julia Yue Cui
      Drug Metabolism and Disposition February 2016, 44 (2) 262-274; DOI: https://doi.org/10.1124/dmd.115.067504
  6. Krishnamurthy, Prasad

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  7. Krzyzewski, Stacy

    1. You have access
      Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism
      T. Eric Ballard, Shuai Wang, Loretta M. Cox, Mark A. Moen, Stacy Krzyzewski, Okechukwu Ukairo and R. Scott Obach
      Drug Metabolism and Disposition February 2016, 44 (2) 172-179; DOI: https://doi.org/10.1124/dmd.115.066688
  8. Kuit, Kathy

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  9. Kumar, Jeyan S.

    1. You have access
      Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
      Lora D. Weidner, King Leung Fung, Pavitra Kannan, Janna K. Moen, Jeyan S. Kumar, Jan Mulder, Robert B. Innis, Michael M. Gottesman and Matthew D. Hall
      Drug Metabolism and Disposition February 2016, 44 (2) 275-282; DOI: https://doi.org/10.1124/dmd.115.067785
  10. Kwit, Alexandra D.T.

    1. You have access
      Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers
      King Leung Fung, Khyati Kapoor, Jessica N. Pixley, Darrell J. Talbert, Alexandra D.T. Kwit, Suresh V. Ambudkar and Michael M. Gottesman
      Drug Metabolism and Disposition February 2016, 44 (2) 180-188; DOI: https://doi.org/10.1124/dmd.115.066506

L

  1. Lai, Yurong

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  2. Lever, Amanda R.

    1. Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      You have access
      Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      Dinelia Rivera-Burgos, Ujjal Sarkar, Amanda R. Lever, Michael J. Avram, Jonathan R. Coppeta, John S. Wishnok, Jeffrey T. Borenstein and Steven R. Tannenbaum
      Drug Metabolism and Disposition February 2016, 44 (2) 220-226; DOI: https://doi.org/10.1124/dmd.115.066365
  3. Liu, Tongtong

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852

M

  1. Mager, Donald E.

    1. You have access
      Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice
      Vidya Ramakrishnan, Qi Joy Yang, Holly P. Quach, Yanguang Cao, Edwin C. Y. Chow, Donald E. Mager and K. Sandy Pang
      Drug Metabolism and Disposition February 2016, 44 (2) 189-208; DOI: https://doi.org/10.1124/dmd.115.067033
  2. Marathe, Punit

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  3. Mintier, Gabe

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  4. Moen, Janna K.

    1. You have access
      Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
      Lora D. Weidner, King Leung Fung, Pavitra Kannan, Janna K. Moen, Jeyan S. Kumar, Jan Mulder, Robert B. Innis, Michael M. Gottesman and Matthew D. Hall
      Drug Metabolism and Disposition February 2016, 44 (2) 275-282; DOI: https://doi.org/10.1124/dmd.115.067785
  5. Moen, Mark A.

    1. You have access
      Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism
      T. Eric Ballard, Shuai Wang, Loretta M. Cox, Mark A. Moen, Stacy Krzyzewski, Okechukwu Ukairo and R. Scott Obach
      Drug Metabolism and Disposition February 2016, 44 (2) 172-179; DOI: https://doi.org/10.1124/dmd.115.066688
  6. Moore, Amanda

    1. You have access
      Application of Micropatterned Cocultured Hepatocytes to Evaluate the Inductive Potential and Degradation Rate of Major Xenobiotic Metabolizing Enzymes
      Vaishali Dixit, Amanda Moore, Hong Tsao and Niresh Hariparsad
      Drug Metabolism and Disposition February 2016, 44 (2) 250-261; DOI: https://doi.org/10.1124/dmd.115.067173
  7. Mulder, Jan

    1. You have access
      Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
      Lora D. Weidner, King Leung Fung, Pavitra Kannan, Janna K. Moen, Jeyan S. Kumar, Jan Mulder, Robert B. Innis, Michael M. Gottesman and Matthew D. Hall
      Drug Metabolism and Disposition February 2016, 44 (2) 275-282; DOI: https://doi.org/10.1124/dmd.115.067785

N

  1. Neunzig, Jens

    1. You have access
      Metabolism of Oral Turinabol by Human Steroid Hormone–Synthesizing Cytochrome P450 Enzymes
      Lina Schiffer, Simone Brixius-Anderko, Frank Hannemann, Josef Zapp, Jens Neunzig, Mario Thevis and Rita Bernhardt
      Drug Metabolism and Disposition February 2016, 44 (2) 227-237; DOI: https://doi.org/10.1124/dmd.115.066829

O

  1. Obach, R. Scott

    1. You have access
      Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism
      T. Eric Ballard, Shuai Wang, Loretta M. Cox, Mark A. Moen, Stacy Krzyzewski, Okechukwu Ukairo and R. Scott Obach
      Drug Metabolism and Disposition February 2016, 44 (2) 172-179; DOI: https://doi.org/10.1124/dmd.115.066688

P

  1. Pang, K. Sandy

    1. You have access
      Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice
      Vidya Ramakrishnan, Qi Joy Yang, Holly P. Quach, Yanguang Cao, Edwin C. Y. Chow, Donald E. Mager and K. Sandy Pang
      Drug Metabolism and Disposition February 2016, 44 (2) 189-208; DOI: https://doi.org/10.1124/dmd.115.067033
  2. Pixley, Jessica N.

    1. You have access
      Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers
      King Leung Fung, Khyati Kapoor, Jessica N. Pixley, Darrell J. Talbert, Alexandra D.T. Kwit, Suresh V. Ambudkar and Michael M. Gottesman
      Drug Metabolism and Disposition February 2016, 44 (2) 180-188; DOI: https://doi.org/10.1124/dmd.115.066506

Q

  1. Qiu, Xi

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  2. Quach, Holly P.

    1. You have access
      Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice
      Vidya Ramakrishnan, Qi Joy Yang, Holly P. Quach, Yanguang Cao, Edwin C. Y. Chow, Donald E. Mager and K. Sandy Pang
      Drug Metabolism and Disposition February 2016, 44 (2) 189-208; DOI: https://doi.org/10.1124/dmd.115.067033

R

  1. Ramakrishnan, Vidya

    1. You have access
      Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice
      Vidya Ramakrishnan, Qi Joy Yang, Holly P. Quach, Yanguang Cao, Edwin C. Y. Chow, Donald E. Mager and K. Sandy Pang
      Drug Metabolism and Disposition February 2016, 44 (2) 189-208; DOI: https://doi.org/10.1124/dmd.115.067033
  2. Rivera-Burgos, Dinelia

    1. Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      You have access
      Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      Dinelia Rivera-Burgos, Ujjal Sarkar, Amanda R. Lever, Michael J. Avram, Jonathan R. Coppeta, John S. Wishnok, Jeffrey T. Borenstein and Steven R. Tannenbaum
      Drug Metabolism and Disposition February 2016, 44 (2) 220-226; DOI: https://doi.org/10.1124/dmd.115.066365
  3. Rodrigues, A. David

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  4. Ryder, Tim

    1. You have access
      Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans
      Jennifer Q. Dong, Manthena V. Varma, Angela Wolford, Tim Ryder, Li Di, Bo Feng, Steven G. Terra, Kazuko Sagawa and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2016, 44 (2) 209-219; DOI: https://doi.org/10.1124/dmd.115.067868

S

  1. Sagawa, Kazuko

    1. You have access
      Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans
      Jennifer Q. Dong, Manthena V. Varma, Angela Wolford, Tim Ryder, Li Di, Bo Feng, Steven G. Terra, Kazuko Sagawa and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2016, 44 (2) 209-219; DOI: https://doi.org/10.1124/dmd.115.067868
  2. Sarkar, Ujjal

    1. Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      You have access
      Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      Dinelia Rivera-Burgos, Ujjal Sarkar, Amanda R. Lever, Michael J. Avram, Jonathan R. Coppeta, John S. Wishnok, Jeffrey T. Borenstein and Steven R. Tannenbaum
      Drug Metabolism and Disposition February 2016, 44 (2) 220-226; DOI: https://doi.org/10.1124/dmd.115.066365
  3. Schiffer, Lina

    1. You have access
      Metabolism of Oral Turinabol by Human Steroid Hormone–Synthesizing Cytochrome P450 Enzymes
      Lina Schiffer, Simone Brixius-Anderko, Frank Hannemann, Josef Zapp, Jens Neunzig, Mario Thevis and Rita Bernhardt
      Drug Metabolism and Disposition February 2016, 44 (2) 227-237; DOI: https://doi.org/10.1124/dmd.115.066829
  4. Selwyn, Felcy Pavithra

    1. You have access
      Regulation of Hepatic Drug-Metabolizing Enzymes in Germ-Free Mice by Conventionalization and Probiotics
      Felcy Pavithra Selwyn, Sunny Lihua Cheng, Curtis D. Klaassen and Julia Yue Cui
      Drug Metabolism and Disposition February 2016, 44 (2) 262-274; DOI: https://doi.org/10.1124/dmd.115.067504
  5. Shen, Hong

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  6. Sprouse, Alyssa A.

    1. You have access
      Pharmacokinetic Interactions between Drugs and Botanical Dietary Supplements
      Alyssa A. Sprouse and Richard B. van Breemen
      Drug Metabolism and Disposition February 2016, 44 (2) 162-171; DOI: https://doi.org/10.1124/dmd.115.066902
  7. Sukrutharaj, Sunil

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852

T

  1. Talbert, Darrell J.

    1. You have access
      Using the BacMam Baculovirus System to Study Expression and Function of Recombinant Efflux Drug Transporters in Polarized Epithelial Cell Monolayers
      King Leung Fung, Khyati Kapoor, Jessica N. Pixley, Darrell J. Talbert, Alexandra D.T. Kwit, Suresh V. Ambudkar and Michael M. Gottesman
      Drug Metabolism and Disposition February 2016, 44 (2) 180-188; DOI: https://doi.org/10.1124/dmd.115.066506
  2. Tannenbaum, Steven R.

    1. Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      You have access
      Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      Dinelia Rivera-Burgos, Ujjal Sarkar, Amanda R. Lever, Michael J. Avram, Jonathan R. Coppeta, John S. Wishnok, Jeffrey T. Borenstein and Steven R. Tannenbaum
      Drug Metabolism and Disposition February 2016, 44 (2) 220-226; DOI: https://doi.org/10.1124/dmd.115.066365
  3. Taylor, Kristin

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  4. Terra, Steven G.

    1. You have access
      Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans
      Jennifer Q. Dong, Manthena V. Varma, Angela Wolford, Tim Ryder, Li Di, Bo Feng, Steven G. Terra, Kazuko Sagawa and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2016, 44 (2) 209-219; DOI: https://doi.org/10.1124/dmd.115.067868
  5. Thevis, Mario

    1. You have access
      Metabolism of Oral Turinabol by Human Steroid Hormone–Synthesizing Cytochrome P450 Enzymes
      Lina Schiffer, Simone Brixius-Anderko, Frank Hannemann, Josef Zapp, Jens Neunzig, Mario Thevis and Rita Bernhardt
      Drug Metabolism and Disposition February 2016, 44 (2) 227-237; DOI: https://doi.org/10.1124/dmd.115.066829
  6. Titsch, Craig

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
  7. Tsao, Hong

    1. You have access
      Application of Micropatterned Cocultured Hepatocytes to Evaluate the Inductive Potential and Degradation Rate of Major Xenobiotic Metabolizing Enzymes
      Vaishali Dixit, Amanda Moore, Hong Tsao and Niresh Hariparsad
      Drug Metabolism and Disposition February 2016, 44 (2) 250-261; DOI: https://doi.org/10.1124/dmd.115.067173

U

  1. Ukairo, Okechukwu

    1. You have access
      Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism
      T. Eric Ballard, Shuai Wang, Loretta M. Cox, Mark A. Moen, Stacy Krzyzewski, Okechukwu Ukairo and R. Scott Obach
      Drug Metabolism and Disposition February 2016, 44 (2) 172-179; DOI: https://doi.org/10.1124/dmd.115.066688

V

  1. van Breemen, Richard B.

    1. You have access
      Pharmacokinetic Interactions between Drugs and Botanical Dietary Supplements
      Alyssa A. Sprouse and Richard B. van Breemen
      Drug Metabolism and Disposition February 2016, 44 (2) 162-171; DOI: https://doi.org/10.1124/dmd.115.066902
  2. Varma, Manthena V.

    1. You have access
      Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans
      Jennifer Q. Dong, Manthena V. Varma, Angela Wolford, Tim Ryder, Li Di, Bo Feng, Steven G. Terra, Kazuko Sagawa and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2016, 44 (2) 209-219; DOI: https://doi.org/10.1124/dmd.115.067868

W

  1. Wang, Shuai

    1. You have access
      Application of a Micropatterned Cocultured Hepatocyte System To Predict Preclinical and Human-Specific Drug Metabolism
      T. Eric Ballard, Shuai Wang, Loretta M. Cox, Mark A. Moen, Stacy Krzyzewski, Okechukwu Ukairo and R. Scott Obach
      Drug Metabolism and Disposition February 2016, 44 (2) 172-179; DOI: https://doi.org/10.1124/dmd.115.066688
  2. Weidner, Lora D.

    1. You have access
      Tariquidar Is an Inhibitor and Not a Substrate of Human and Mouse P-glycoprotein
      Lora D. Weidner, King Leung Fung, Pavitra Kannan, Janna K. Moen, Jeyan S. Kumar, Jan Mulder, Robert B. Innis, Michael M. Gottesman and Matthew D. Hall
      Drug Metabolism and Disposition February 2016, 44 (2) 275-282; DOI: https://doi.org/10.1124/dmd.115.067785
  3. Wishnok, John S.

    1. Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      You have access
      Glucocorticoid Clearance and Metabolite Profiling in an In Vitro Human Airway Epithelium Lung Model
      Dinelia Rivera-Burgos, Ujjal Sarkar, Amanda R. Lever, Michael J. Avram, Jonathan R. Coppeta, John S. Wishnok, Jeffrey T. Borenstein and Steven R. Tannenbaum
      Drug Metabolism and Disposition February 2016, 44 (2) 220-226; DOI: https://doi.org/10.1124/dmd.115.066365
  4. Wolford, Angela

    1. You have access
      Pharmacokinetics and Disposition of the Thiouracil Derivative PF-06282999, an Orally Bioavailable, Irreversible Inactivator of Myeloperoxidase Enzyme, Across Animals and Humans
      Jennifer Q. Dong, Manthena V. Varma, Angela Wolford, Tim Ryder, Li Di, Bo Feng, Steven G. Terra, Kazuko Sagawa and Amit S. Kalgutkar
      Drug Metabolism and Disposition February 2016, 44 (2) 209-219; DOI: https://doi.org/10.1124/dmd.115.067868

Y

  1. Yang, Qi Joy

    1. You have access
      Physiologically-Based Pharmacokinetic-Pharmacodynamic Modeling of 1α,25-Dihydroxyvitamin D3 in Mice
      Vidya Ramakrishnan, Qi Joy Yang, Holly P. Quach, Yanguang Cao, Edwin C. Y. Chow, Donald E. Mager and K. Sandy Pang
      Drug Metabolism and Disposition February 2016, 44 (2) 189-208; DOI: https://doi.org/10.1124/dmd.115.067033

Z

  1. Zapp, Josef

    1. You have access
      Metabolism of Oral Turinabol by Human Steroid Hormone–Synthesizing Cytochrome P450 Enzymes
      Lina Schiffer, Simone Brixius-Anderko, Frank Hannemann, Josef Zapp, Jens Neunzig, Mario Thevis and Rita Bernhardt
      Drug Metabolism and Disposition February 2016, 44 (2) 227-237; DOI: https://doi.org/10.1124/dmd.115.066829
  2. Zeng, Jianing

    1. You have access
      Cynomolgus Monkey as a Clinically Relevant Model to Study Transport Involving Renal Organic Cation Transporters: In Vitro and In Vivo Evaluation
      Hong Shen, Tongtong Liu, Hao Jiang, Craig Titsch, Kristin Taylor, Hamza Kandoussi, Xi Qiu, Cliff Chen, Sunil Sukrutharaj, Kathy Kuit, Gabe Mintier, Prasad Krishnamurthy, R. Marcus Fancher, Jianing Zeng, A. David Rodrigues, Punit Marathe and Yurong Lai
      Drug Metabolism and Disposition February 2016, 44 (2) 238-249; DOI: https://doi.org/10.1124/dmd.115.066852
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Drug Metabolism and Disposition: 44 (2)
Drug Metabolism and Disposition
Vol. 44, Issue 2
1 Feb 2016
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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