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Research ArticleArticle

Application of Micropatterned Cocultured Hepatocytes to Evaluate the Inductive Potential and Degradation Rate of Major Xenobiotic Metabolizing Enzymes

Vaishali Dixit, Amanda Moore, Hong Tsao and Niresh Hariparsad
Drug Metabolism and Disposition February 2016, 44 (2) 250-261; DOI: https://doi.org/10.1124/dmd.115.067173

Article Information

vol. 44 no. 2 250-261
DOI 
https://doi.org/10.1124/dmd.115.067173
PubMed 
26658225
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received September 11, 2015
  • Accepted December 8, 2015
  • Published online January 16, 2016.

Article Versions

Copyright & Usage 
Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Vaishali Dixit,
  2. Amanda Moore,
  3. Hong Tsao, and
  4. Niresh Hariparsad
  1. Drug Metabolism and Pharmacokinetics, Vertex Pharmaceuticals Incorporated, Boston, Massachusetts
  1. Address correspondence to:
    Dr. Niresh Hariparsad, 4019E Vertex 1, 50 Northern Drive, Boston, MA 02210. E-mail: niresh_hariparsad{at}vrtx.com
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Hepatocyte Coculture System to Assess P450 Induction

Vaishali Dixit, Amanda Moore, Hong Tsao and Niresh Hariparsad
Drug Metabolism and Disposition February 1, 2016, 44 (2) 250-261; DOI: https://doi.org/10.1124/dmd.115.067173
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