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Drug Metabolism & Disposition

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  • Articles
    • Current Issue
    • Fast Forward
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Index by author

March 01, 2016; Volume 44,Issue 3
  • A
  • B
  • C
  • D
  • E
  • F
  • G
  • H
  • I
  • J
  • K
  • L
  • M
  • N
  • O
  • P
  • Q
  • R
  • S
  • T
  • U
  • V
  • W
  • X
  • Y
  • Z

A

  1. Achour, Brahim

    1. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
    2. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
  2. Annaert, Pieter

    1. You have access
      Transport-Metabolism Interplay of Atazanavir in Rat Hepatocytes
      Johan Nicolaï, Tom De Bruyn, Louise Thevelin, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition March 2016, 44 (3) 389-397; DOI: https://doi.org/10.1124/dmd.115.068114
  3. Atkinson, Karen

    1. You have access
      Novel Cytochrome P450 Reaction Phenotyping for Low-Clearance Compounds Using the Hepatocyte Relay Method
      Xin Yang, Karen Atkinson and Li Di
      Drug Metabolism and Disposition March 2016, 44 (3) 460-465; DOI: https://doi.org/10.1124/dmd.115.067876
  4. Augustijns, Patrick

    1. You have access
      Transport-Metabolism Interplay of Atazanavir in Rat Hepatocytes
      Johan Nicolaï, Tom De Bruyn, Louise Thevelin, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition March 2016, 44 (3) 389-397; DOI: https://doi.org/10.1124/dmd.115.068114

B

  1. Bi, Huichang

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  2. Bischoff, Daniel

    1. You have access
      Upcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable Compounds
      Michelle Schaefer, Gerhard Schänzle, Daniel Bischoff and Roderich D. Süssmuth
      Drug Metabolism and Disposition March 2016, 44 (3) 435-444; DOI: https://doi.org/10.1124/dmd.115.067348
  3. Bromek, Ewa

    1. You have access
      Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain
      Anna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska and Władysława A. Daniel
      Drug Metabolism and Disposition March 2016, 44 (3) 445-452; DOI: https://doi.org/10.1124/dmd.115.067413
  4. Buckley, David B.

    1. You have access
      Evaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug Transporters
      Lydia M. M. Vermeer, Caleb D. Isringhausen, Brian W. Ogilvie and David B. Buckley
      Drug Metabolism and Disposition March 2016, 44 (3) 453-459; DOI: https://doi.org/10.1124/dmd.115.067744
  5. Burton, Aimee

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736

C

  1. Carlson, Gordon

    1. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
    2. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
  2. Carmella, Steven G.

    1. Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      You have access
      Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      Sreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo Xing
      Drug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
  3. Chapron, Brian D.

    1. You have access
      Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism
      Yoshiyuki Yamaura, Brian D. Chapron, Zhican Wang, Jonathan Himmelfarb and Kenneth E. Thummel
      Drug Metabolism and Disposition March 2016, 44 (3) 329-335; DOI: https://doi.org/10.1124/dmd.115.068429
  4. Chaudhry, Amarjit S.

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
  5. Chavez-Eng, Cynthia

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
  6. Chen, Pan

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  7. Chen, Yixin

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  8. Chien, Huan-Chieh

    1. You have access
      Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 Cells
      Huan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. Giacomini
      Drug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
  9. Cooper, Curtis

    1. You have access
      Contribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo Outcomes
      Rucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
  10. Csanaky, Iván L.

    1. You have access
      Calorie Restriction Increases P-Glycoprotein and Decreases Intestinal Absorption of Digoxin in Mice
      Helen J. Renaud, Curtis D. Klaassen and Iván L. Csanaky
      Drug Metabolism and Disposition March 2016, 44 (3) 366-369; DOI: https://doi.org/10.1124/dmd.115.064766

D

  1. Daniel, Władysława A.

    1. You have access
      Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain
      Anna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska and Władysława A. Daniel
      Drug Metabolism and Disposition March 2016, 44 (3) 445-452; DOI: https://doi.org/10.1124/dmd.115.067413
  2. De Bruyn, Tom

    1. You have access
      Transport-Metabolism Interplay of Atazanavir in Rat Hepatocytes
      Johan Nicolaï, Tom De Bruyn, Louise Thevelin, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition March 2016, 44 (3) 389-397; DOI: https://doi.org/10.1124/dmd.115.068114
  3. Di, Li

    1. You have access
      Novel Cytochrome P450 Reaction Phenotyping for Low-Clearance Compounds Using the Hepatocyte Relay Method
      Xin Yang, Karen Atkinson and Li Di
      Drug Metabolism and Disposition March 2016, 44 (3) 460-465; DOI: https://doi.org/10.1124/dmd.115.067876

E

  1. Elsby, Robert

    1. You have access
      Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure
      Robert Elsby, Paul Martin, Dominic Surry, Pradeep Sharma and Katherine Fenner
      Drug Metabolism and Disposition March 2016, 44 (3) 398-408; DOI: https://doi.org/10.1124/dmd.115.066795

F

  1. Fan, Xiaomei

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  2. Fenner, Katherine

    1. You have access
      Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure
      Robert Elsby, Paul Martin, Dominic Surry, Pradeep Sharma and Katherine Fenner
      Drug Metabolism and Disposition March 2016, 44 (3) 398-408; DOI: https://doi.org/10.1124/dmd.115.066795
  3. Fukami, Tatsuki

    1. You have access
      Arylacetamide Deacetylase is Responsible for Activation of Prasugrel in Human and Dog
      Takaya Kurokawa, Tatsuki Fukami, Tomohiro Yoshida and Miki Nakajima
      Drug Metabolism and Disposition March 2016, 44 (3) 409-416; DOI: https://doi.org/10.1124/dmd.115.068221
  4. Furlong, Michael T.

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944

G

  1. Gheyas, Ferdous

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
  2. Giacomini, Kathleen M.

    1. You have access
      Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 Cells
      Huan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. Giacomini
      Drug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
  3. Gołembiowska, Krystyna

    1. You have access
      Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain
      Anna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska and Władysława A. Daniel
      Drug Metabolism and Disposition March 2016, 44 (3) 445-452; DOI: https://doi.org/10.1124/dmd.115.067413
  4. Gutstein, David

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736

H

  1. Haduch, Anna

    1. You have access
      Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain
      Anna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska and Władysława A. Daniel
      Drug Metabolism and Disposition March 2016, 44 (3) 445-452; DOI: https://doi.org/10.1124/dmd.115.067413
  2. Han, Yong-Hae

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
  3. Hartmann, Georgy

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
  4. Harwood, Matthew D.

    1. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
    2. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
  5. Hecht, Stephen S.

    1. Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      You have access
      Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      Sreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo Xing
      Drug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
  6. Himmelfarb, Jonathan

    1. You have access
      Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism
      Yoshiyuki Yamaura, Brian D. Chapron, Zhican Wang, Jonathan Himmelfarb and Kenneth E. Thummel
      Drug Metabolism and Disposition March 2016, 44 (3) 329-335; DOI: https://doi.org/10.1124/dmd.115.068429
  7. Ho, Pui Yan

    1. You have access
      MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy
      Ai-Ming Yu, Ye Tian, Mei-Juan Tu, Pui Yan Ho and Joseph L. Jilek
      Drug Metabolism and Disposition March 2016, 44 (3) 308-319; DOI: https://doi.org/10.1124/dmd.115.067470
  8. Hu, Ming

    1. You have access
      SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats
      Jian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
  9. Huang, Min

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969

I

  1. Isringhausen, Caleb D.

    1. You have access
      Evaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug Transporters
      Lydia M. M. Vermeer, Caleb D. Isringhausen, Brian W. Ogilvie and David B. Buckley
      Drug Metabolism and Disposition March 2016, 44 (3) 453-459; DOI: https://doi.org/10.1124/dmd.115.067744
  2. Iyer, Ramaswamy A.

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944

J

  1. Jackson, Tonya

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
  2. Jasper, Paul

    1. You have access
      Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 Cells
      Huan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. Giacomini
      Drug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
  3. Jeong, Hyunyoung

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
  4. Jiang, Yiming

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  5. Jilek, Joseph L.

    1. You have access
      MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy
      Ai-Ming Yu, Ye Tian, Mei-Juan Tu, Pui Yan Ho and Joseph L. Jilek
      Drug Metabolism and Disposition March 2016, 44 (3) 308-319; DOI: https://doi.org/10.1124/dmd.115.067470
  6. Johns, Douglas

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736

K

  1. Katoh, Miki

    1. You have access
      Effects of Phenobarbital on Expression of UDP-Glucuronosyltransferase 1a6 and 1a7 in Rat Brain
      Yukiko Sakakibara, Miki Katoh, Yuya Kondo and Masayuki Nadai
      Drug Metabolism and Disposition March 2016, 44 (3) 370-377; DOI: https://doi.org/10.1124/dmd.115.067439
  2. Klaassen, Curtis D.

    1. You have access
      Calorie Restriction Increases P-Glycoprotein and Decreases Intestinal Absorption of Digoxin in Mice
      Helen J. Renaud, Curtis D. Klaassen and Iván L. Csanaky
      Drug Metabolism and Disposition March 2016, 44 (3) 366-369; DOI: https://doi.org/10.1124/dmd.115.064766
  3. Kocarek, Thomas A.

    1. You have access
      Role of Phosphatidic Acid Phosphatase Domain Containing 2 in Squalestatin 1–Mediated Activation of the Constitutive Androstane Receptor in Primary Cultured Rat Hepatocytes
      Asmita Pant and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2016, 44 (3) 352-355; DOI: https://doi.org/10.1124/dmd.115.068437
  4. Kole, Prashant

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
  5. Kondo, Yuya

    1. You have access
      Effects of Phenobarbital on Expression of UDP-Glucuronosyltransferase 1a6 and 1a7 in Rat Brain
      Yukiko Sakakibara, Miki Katoh, Yuya Kondo and Masayuki Nadai
      Drug Metabolism and Disposition March 2016, 44 (3) 370-377; DOI: https://doi.org/10.1124/dmd.115.067439
  6. Kumar, Sanjeev

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
  7. Kurokawa, Takaya

    1. You have access
      Arylacetamide Deacetylase is Responsible for Activation of Prasugrel in Human and Dog
      Takaya Kurokawa, Tatsuki Fukami, Tomohiro Yoshida and Miki Nakajima
      Drug Metabolism and Disposition March 2016, 44 (3) 409-416; DOI: https://doi.org/10.1124/dmd.115.068221

L

  1. Lai, Yurong

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
  2. Lederman, Harmony

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
  3. Leitzman, Pablo

    1. Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      You have access
      Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      Sreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo Xing
      Drug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
  4. Li, Dongshun

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  5. Li, Xi

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  6. Lin, Yvonne S.

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
  7. Liu, Tongtong

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
  8. Liu, Zhongqiu

    1. You have access
      SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats
      Jian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
  9. Lu, Linlin

    1. You have access
      SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats
      Jian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
  10. Lutz, Ryan

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736

M

  1. Mandlekar, Sandhya

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
  2. Marathe, Punit

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
  3. Martin, Paul

    1. You have access
      Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure
      Robert Elsby, Paul Martin, Dominic Surry, Pradeep Sharma and Katherine Fenner
      Drug Metabolism and Disposition March 2016, 44 (3) 398-408; DOI: https://doi.org/10.1124/dmd.115.066795
  4. Matta, Murali Krishna

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
  5. Maurer, Tristan S.

    1. You have access
      Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 Cells
      Huan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. Giacomini
      Drug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
  6. Miners, John O.

    1. You have access
      Human UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme Inhibition
      Attarat Pattanawongsa, Pramod C. Nair, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition March 2016, 44 (3) 378-388; DOI: https://doi.org/10.1124/dmd.115.068213
  7. Mitra, Kaushik

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
  8. Murphy, Sharon E.

    1. Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      You have access
      Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      Sreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo Xing
      Drug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387

N

  1. Nadai, Masayuki

    1. You have access
      Effects of Phenobarbital on Expression of UDP-Glucuronosyltransferase 1a6 and 1a7 in Rat Brain
      Yukiko Sakakibara, Miki Katoh, Yuya Kondo and Masayuki Nadai
      Drug Metabolism and Disposition March 2016, 44 (3) 370-377; DOI: https://doi.org/10.1124/dmd.115.067439
  2. Nair, Pramod C.

    1. You have access
      Human UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme Inhibition
      Attarat Pattanawongsa, Pramod C. Nair, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition March 2016, 44 (3) 378-388; DOI: https://doi.org/10.1124/dmd.115.068213
  3. Nakajima, Miki

    1. You have access
      Arylacetamide Deacetylase is Responsible for Activation of Prasugrel in Human and Dog
      Takaya Kurokawa, Tatsuki Fukami, Tomohiro Yoshida and Miki Nakajima
      Drug Metabolism and Disposition March 2016, 44 (3) 409-416; DOI: https://doi.org/10.1124/dmd.115.068221
  4. Narayanapillai, Sreekanth C.

    1. Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      You have access
      Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      Sreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo Xing
      Drug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
  5. Neuhoff, Sibylle

    1. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
    2. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
  6. Nicolaï, Johan

    1. You have access
      Transport-Metabolism Interplay of Atazanavir in Rat Hepatocytes
      Johan Nicolaï, Tom De Bruyn, Louise Thevelin, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition March 2016, 44 (3) 389-397; DOI: https://doi.org/10.1124/dmd.115.068114

O

  1. Ogilvie, Brian W.

    1. You have access
      Evaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug Transporters
      Lydia M. M. Vermeer, Caleb D. Isringhausen, Brian W. Ogilvie and David B. Buckley
      Drug Metabolism and Disposition March 2016, 44 (3) 453-459; DOI: https://doi.org/10.1124/dmd.115.067744

P

  1. Paladino, Jordan

    1. Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      You have access
      Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      Sreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo Xing
      Drug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
  2. Pan, Xian

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
  3. Pant, Asmita

    1. You have access
      Role of Phosphatidic Acid Phosphatase Domain Containing 2 in Squalestatin 1–Mediated Activation of the Constitutive Androstane Receptor in Primary Cultured Rat Hepatocytes
      Asmita Pant and Thomas A. Kocarek
      Drug Metabolism and Disposition March 2016, 44 (3) 352-355; DOI: https://doi.org/10.1124/dmd.115.068437
  4. Patrick, Kennerly S.

    1. You have access
      Absorption Differences between Immediate-Release Dexmethylphenidate and dl-Methylphenidate
      Kennerly S. Patrick and Arthur B. Straughn
      Drug Metabolism and Disposition March 2016, 44 (3) 418-421; DOI: https://doi.org/10.1124/dmd.115.067975
  5. Pattanawongsa, Attarat

    1. You have access
      Human UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme Inhibition
      Attarat Pattanawongsa, Pramod C. Nair, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition March 2016, 44 (3) 378-388; DOI: https://doi.org/10.1124/dmd.115.068213
  6. Prasad, Bhagwat

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
  7. Putluru, Siva Prasad

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944

Q

  1. Qin, Xiaoling

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969

R

  1. Ramsden, Diane

    1. You have access
      Contribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo Outcomes
      Rucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
  2. Renaud, Helen J.

    1. You have access
      Calorie Restriction Increases P-Glycoprotein and Decreases Intestinal Absorption of Digoxin in Mice
      Helen J. Renaud, Curtis D. Klaassen and Iván L. Csanaky
      Drug Metabolism and Disposition March 2016, 44 (3) 366-369; DOI: https://doi.org/10.1124/dmd.115.064766
  3. Rodrigues, A. David

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
  4. Rostami-Hodjegan, Amin

    1. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
    2. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
  5. Rowland, Andrew

    1. You have access
      Human UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme Inhibition
      Attarat Pattanawongsa, Pramod C. Nair, Andrew Rowland and John O. Miners
      Drug Metabolism and Disposition March 2016, 44 (3) 378-388; DOI: https://doi.org/10.1124/dmd.115.068213
  6. Rowland, Lois

    1. You have access
      Contribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo Outcomes
      Rucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
  7. Russell, Matthew R.

    1. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
    2. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777

S

  1. Sabo, John P.

    1. You have access
      Contribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo Outcomes
      Rucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
  2. Sakakibara, Yukiko

    1. You have access
      Effects of Phenobarbital on Expression of UDP-Glucuronosyltransferase 1a6 and 1a7 in Rat Brain
      Yukiko Sakakibara, Miki Katoh, Yuya Kondo and Masayuki Nadai
      Drug Metabolism and Disposition March 2016, 44 (3) 370-377; DOI: https://doi.org/10.1124/dmd.115.067439
  3. Sane, Rucha S.

    1. You have access
      Contribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo Outcomes
      Rucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
  4. Schaefer, Michelle

    1. You have access
      Upcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable Compounds
      Michelle Schaefer, Gerhard Schänzle, Daniel Bischoff and Roderich D. Süssmuth
      Drug Metabolism and Disposition March 2016, 44 (3) 435-444; DOI: https://doi.org/10.1124/dmd.115.067348
  5. Schänzle, Gerhard

    1. You have access
      Upcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable Compounds
      Michelle Schaefer, Gerhard Schänzle, Daniel Bischoff and Roderich D. Süssmuth
      Drug Metabolism and Disposition March 2016, 44 (3) 435-444; DOI: https://doi.org/10.1124/dmd.115.067348
  6. Schuetz, Erin G.

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
  7. Scott, Dennis O.

    1. You have access
      Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 Cells
      Huan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. Giacomini
      Drug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
  8. Sharma, Pradeep

    1. You have access
      Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure
      Robert Elsby, Paul Martin, Dominic Surry, Pradeep Sharma and Katherine Fenner
      Drug Metabolism and Disposition March 2016, 44 (3) 398-408; DOI: https://doi.org/10.1124/dmd.115.066795
  9. Shen, Xiaolan

    1. You have access
      Disposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in Mice
      Georgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik Mitra
      Drug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
  10. Shi, Jian

    1. You have access
      SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats
      Jian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
  11. Shireman, Laura M.

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
  12. Straughn, Arthur B.

    1. You have access
      Absorption Differences between Immediate-Release Dexmethylphenidate and dl-Methylphenidate
      Kennerly S. Patrick and Arthur B. Straughn
      Drug Metabolism and Disposition March 2016, 44 (3) 418-421; DOI: https://doi.org/10.1124/dmd.115.067975
  13. Surry, Dominic

    1. You have access
      Solitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin Exposure
      Robert Elsby, Paul Martin, Dominic Surry, Pradeep Sharma and Katherine Fenner
      Drug Metabolism and Disposition March 2016, 44 (3) 398-408; DOI: https://doi.org/10.1124/dmd.115.066795
  14. Süssmuth, Roderich D.

    1. You have access
      Upcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable Compounds
      Michelle Schaefer, Gerhard Schänzle, Daniel Bischoff and Roderich D. Süssmuth
      Drug Metabolism and Disposition March 2016, 44 (3) 435-444; DOI: https://doi.org/10.1124/dmd.115.067348

T

  1. Tan, Huasen

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  2. Tay-Sontheimer, Jessica

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
  3. Thevelin, Louise

    1. You have access
      Transport-Metabolism Interplay of Atazanavir in Rat Hepatocytes
      Johan Nicolaï, Tom De Bruyn, Louise Thevelin, Patrick Augustijns and Pieter Annaert
      Drug Metabolism and Disposition March 2016, 44 (3) 389-397; DOI: https://doi.org/10.1124/dmd.115.068114
  4. Thummel, Kenneth E.

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
    2. You have access
      Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism
      Yoshiyuki Yamaura, Brian D. Chapron, Zhican Wang, Jonathan Himmelfarb and Kenneth E. Thummel
      Drug Metabolism and Disposition March 2016, 44 (3) 329-335; DOI: https://doi.org/10.1124/dmd.115.068429
  5. Tian, Ye

    1. You have access
      MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy
      Ai-Ming Yu, Ye Tian, Mei-Juan Tu, Pui Yan Ho and Joseph L. Jilek
      Drug Metabolism and Disposition March 2016, 44 (3) 308-319; DOI: https://doi.org/10.1124/dmd.115.067470
  6. Tien, Yun-Chen

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
  7. Ting, Naitee

    1. You have access
      Contribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo Outcomes
      Rucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
  8. Tolsma, John

    1. You have access
      Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 Cells
      Huan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. Giacomini
      Drug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
  9. Tracy, Timothy S.

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
  10. Tu, Mei-Juan

    1. You have access
      MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy
      Ai-Ming Yu, Ye Tian, Mei-Juan Tu, Pui Yan Ho and Joseph L. Jilek
      Drug Metabolism and Disposition March 2016, 44 (3) 308-319; DOI: https://doi.org/10.1124/dmd.115.067470
  11. Tweedie, Donald J.

    1. You have access
      Contribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo Outcomes
      Rucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985

U

  1. Upadhyaya, Pramod

    1. Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      You have access
      Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      Sreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo Xing
      Drug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387

V

  1. Vermeer, Lydia M. M.

    1. You have access
      Evaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug Transporters
      Lydia M. M. Vermeer, Caleb D. Isringhausen, Brian W. Ogilvie and David B. Buckley
      Drug Metabolism and Disposition March 2016, 44 (3) 453-459; DOI: https://doi.org/10.1124/dmd.115.067744
  2. von Weymarn, Linda B.

    1. Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      You have access
      Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      Sreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo Xing
      Drug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387

W

  1. Wang, Ying

    1. You have access
      SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats
      Jian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
    2. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  2. Wang, Zhican

    1. You have access
      Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism
      Yoshiyuki Yamaura, Brian D. Chapron, Zhican Wang, Jonathan Himmelfarb and Kenneth E. Thummel
      Drug Metabolism and Disposition March 2016, 44 (3) 329-335; DOI: https://doi.org/10.1124/dmd.115.068429
  3. Warhurst, Geoffrey

    1. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 Cells
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
    2. You have access
      In Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug Disposition
      Matthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-Hodjegan
      Drug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
  4. Whitcher-Johnstone, Andrea

    1. You have access
      Contribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo Outcomes
      Rucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. Tweedie
      Drug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
  5. Wójcikowski, Jacek

    1. You have access
      Melatonin Supports CYP2D-Mediated Serotonin Synthesis in the Brain
      Anna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska and Władysława A. Daniel
      Drug Metabolism and Disposition March 2016, 44 (3) 445-452; DOI: https://doi.org/10.1124/dmd.115.067413
  6. Wu, Peng

    1. You have access
      SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats
      Jian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009

X

  1. Xing, Chengguo

    1. Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      You have access
      Dietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its Detoxification
      Sreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo Xing
      Drug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387

Y

  1. Yamaura, Yoshiyuki

    1. You have access
      Functional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass Metabolism
      Yoshiyuki Yamaura, Brian D. Chapron, Zhican Wang, Jonathan Himmelfarb and Kenneth E. Thummel
      Drug Metabolism and Disposition March 2016, 44 (3) 329-335; DOI: https://doi.org/10.1124/dmd.115.068429
  2. Yan, Tongmeng

    1. You have access
      SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats
      Jian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
  3. Yang, Xin

    1. You have access
      Novel Cytochrome P450 Reaction Phenotyping for Low-Clearance Compounds Using the Hepatocyte Relay Method
      Xin Yang, Karen Atkinson and Li Di
      Drug Metabolism and Disposition March 2016, 44 (3) 460-465; DOI: https://doi.org/10.1124/dmd.115.067876
  4. Yang, Zheng

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
  5. Yee, Sook Wah

    1. You have access
      Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 Cells
      Huan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. Giacomini
      Drug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
  6. Yoshida, Tomohiro

    1. You have access
      Arylacetamide Deacetylase is Responsible for Activation of Prasugrel in Human and Dog
      Takaya Kurokawa, Tatsuki Fukami, Tomohiro Yoshida and Miki Nakajima
      Drug Metabolism and Disposition March 2016, 44 (3) 409-416; DOI: https://doi.org/10.1124/dmd.115.068221
  7. Yu, Ai-Ming

    1. You have access
      MicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective Therapy
      Ai-Ming Yu, Ye Tian, Mei-Juan Tu, Pui Yan Ho and Joseph L. Jilek
      Drug Metabolism and Disposition March 2016, 44 (3) 308-319; DOI: https://doi.org/10.1124/dmd.115.067470
  8. Yu, Jia

    1. You have access
      SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats
      Jian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009

Z

  1. Zeng, Hang

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  2. Zeng, Xuezhen

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  3. Zhang, Yueping

    1. You have access
      Diclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In Vitro
      Yueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David Rodrigues
      Drug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
  4. Zheng, Haihui

    1. You have access
      SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats
      Jian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
  5. Zhong, Xiao-bo

    1. You have access
      Interindividual Variability in Cytochrome P450–Mediated Drug Metabolism
      Timothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. Lin
      Drug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
  6. Zhou, Yawen

    1. You have access
      Hepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver Regeneration
      Hang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang Bi
      Drug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
  7. Zhu, Lijun

    1. You have access
      SGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in Rats
      Jian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu Liu
      Drug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
  8. Zur, Arik A.

    1. You have access
      Rapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 Cells
      Huan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. Giacomini
      Drug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
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Drug Metabolism and Disposition: 44 (3)
Drug Metabolism and Disposition
Vol. 44, Issue 3
1 Mar 2016
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  • Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.
  • Prediction of Human Clearance of Twenty-Nine Drugs from Hepatic Microsomal Intrinsic Clearance Data: An Examination of In Vitro Half-Life Approach and Nonspecific Binding to Microsomes
  • DRUG-DRUG INTERACTIONS FOR UDP-GLUCURONOSYLTRANSFERASE SUBSTRATES: A PHARMACOKINETIC EXPLANATION FOR TYPICALLY OBSERVED LOW EXPOSURE (AUCI/AUC) RATIOS
  • In Vitro-In Vivo Scaling of CYP Kinetic Data Not Consistent with the Classical Michaelis-Menten Model
  • THE HUMAN INTESTINAL CYTOCHROME P450 “PIE”
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