Index by author
March 01, 2016; Volume 44,Issue 3
A
Achour, Brahim
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 CellsMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug DispositionMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
Annaert, Pieter
- You have accessTransport-Metabolism Interplay of Atazanavir in Rat HepatocytesJohan Nicolaï, Tom De Bruyn, Louise Thevelin, Patrick Augustijns and Pieter AnnaertDrug Metabolism and Disposition March 2016, 44 (3) 389-397; DOI: https://doi.org/10.1124/dmd.115.068114
Atkinson, Karen
- You have accessNovel Cytochrome P450 Reaction Phenotyping for Low-Clearance Compounds Using the Hepatocyte Relay MethodXin Yang, Karen Atkinson and Li DiDrug Metabolism and Disposition March 2016, 44 (3) 460-465; DOI: https://doi.org/10.1124/dmd.115.067876
Augustijns, Patrick
- You have accessTransport-Metabolism Interplay of Atazanavir in Rat HepatocytesJohan Nicolaï, Tom De Bruyn, Louise Thevelin, Patrick Augustijns and Pieter AnnaertDrug Metabolism and Disposition March 2016, 44 (3) 389-397; DOI: https://doi.org/10.1124/dmd.115.068114
B
Bi, Huichang
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Bischoff, Daniel
- You have accessUpcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable CompoundsMichelle Schaefer, Gerhard Schänzle, Daniel Bischoff and Roderich D. SüssmuthDrug Metabolism and Disposition March 2016, 44 (3) 435-444; DOI: https://doi.org/10.1124/dmd.115.067348
Bromek, Ewa
- You have accessMelatonin Supports CYP2D-Mediated Serotonin Synthesis in the BrainAnna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska and Władysława A. DanielDrug Metabolism and Disposition March 2016, 44 (3) 445-452; DOI: https://doi.org/10.1124/dmd.115.067413
Buckley, David B.
- You have accessEvaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug TransportersLydia M. M. Vermeer, Caleb D. Isringhausen, Brian W. Ogilvie and David B. BuckleyDrug Metabolism and Disposition March 2016, 44 (3) 453-459; DOI: https://doi.org/10.1124/dmd.115.067744
Burton, Aimee
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
C
Carlson, Gordon
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 CellsMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug DispositionMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
Carmella, Steven G.
- You have accessDietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its DetoxificationSreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo XingDrug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
Chapron, Brian D.
- You have accessFunctional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass MetabolismYoshiyuki Yamaura, Brian D. Chapron, Zhican Wang, Jonathan Himmelfarb and Kenneth E. ThummelDrug Metabolism and Disposition March 2016, 44 (3) 329-335; DOI: https://doi.org/10.1124/dmd.115.068429
Chaudhry, Amarjit S.
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
Chavez-Eng, Cynthia
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
Chen, Pan
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Chen, Yixin
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Chien, Huan-Chieh
- You have accessRapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 CellsHuan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. GiacominiDrug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
Cooper, Curtis
- You have accessContribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo OutcomesRucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. TweedieDrug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
Csanaky, Iván L.
- You have accessCalorie Restriction Increases P-Glycoprotein and Decreases Intestinal Absorption of Digoxin in MiceHelen J. Renaud, Curtis D. Klaassen and Iván L. CsanakyDrug Metabolism and Disposition March 2016, 44 (3) 366-369; DOI: https://doi.org/10.1124/dmd.115.064766
D
Daniel, Władysława A.
- You have accessMelatonin Supports CYP2D-Mediated Serotonin Synthesis in the BrainAnna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska and Władysława A. DanielDrug Metabolism and Disposition March 2016, 44 (3) 445-452; DOI: https://doi.org/10.1124/dmd.115.067413
De Bruyn, Tom
- You have accessTransport-Metabolism Interplay of Atazanavir in Rat HepatocytesJohan Nicolaï, Tom De Bruyn, Louise Thevelin, Patrick Augustijns and Pieter AnnaertDrug Metabolism and Disposition March 2016, 44 (3) 389-397; DOI: https://doi.org/10.1124/dmd.115.068114
Di, Li
- You have accessNovel Cytochrome P450 Reaction Phenotyping for Low-Clearance Compounds Using the Hepatocyte Relay MethodXin Yang, Karen Atkinson and Li DiDrug Metabolism and Disposition March 2016, 44 (3) 460-465; DOI: https://doi.org/10.1124/dmd.115.067876
E
Elsby, Robert
- You have accessSolitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin ExposureRobert Elsby, Paul Martin, Dominic Surry, Pradeep Sharma and Katherine FennerDrug Metabolism and Disposition March 2016, 44 (3) 398-408; DOI: https://doi.org/10.1124/dmd.115.066795
F
Fan, Xiaomei
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Fenner, Katherine
- You have accessSolitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin ExposureRobert Elsby, Paul Martin, Dominic Surry, Pradeep Sharma and Katherine FennerDrug Metabolism and Disposition March 2016, 44 (3) 398-408; DOI: https://doi.org/10.1124/dmd.115.066795
Fukami, Tatsuki
- You have accessArylacetamide Deacetylase is Responsible for Activation of Prasugrel in Human and DogTakaya Kurokawa, Tatsuki Fukami, Tomohiro Yoshida and Miki NakajimaDrug Metabolism and Disposition March 2016, 44 (3) 409-416; DOI: https://doi.org/10.1124/dmd.115.068221
Furlong, Michael T.
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
G
Gheyas, Ferdous
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
Giacomini, Kathleen M.
- You have accessRapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 CellsHuan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. GiacominiDrug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
Gołembiowska, Krystyna
- You have accessMelatonin Supports CYP2D-Mediated Serotonin Synthesis in the BrainAnna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska and Władysława A. DanielDrug Metabolism and Disposition March 2016, 44 (3) 445-452; DOI: https://doi.org/10.1124/dmd.115.067413
Gutstein, David
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
H
Haduch, Anna
- You have accessMelatonin Supports CYP2D-Mediated Serotonin Synthesis in the BrainAnna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska and Władysława A. DanielDrug Metabolism and Disposition March 2016, 44 (3) 445-452; DOI: https://doi.org/10.1124/dmd.115.067413
Han, Yong-Hae
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
Hartmann, Georgy
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
Harwood, Matthew D.
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 CellsMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug DispositionMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
Hecht, Stephen S.
- You have accessDietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its DetoxificationSreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo XingDrug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
Himmelfarb, Jonathan
- You have accessFunctional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass MetabolismYoshiyuki Yamaura, Brian D. Chapron, Zhican Wang, Jonathan Himmelfarb and Kenneth E. ThummelDrug Metabolism and Disposition March 2016, 44 (3) 329-335; DOI: https://doi.org/10.1124/dmd.115.068429
Ho, Pui Yan
- You have accessMicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective TherapyAi-Ming Yu, Ye Tian, Mei-Juan Tu, Pui Yan Ho and Joseph L. JilekDrug Metabolism and Disposition March 2016, 44 (3) 308-319; DOI: https://doi.org/10.1124/dmd.115.067470
Hu, Ming
- You have accessSGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in RatsJian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
Huang, Min
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
I
Isringhausen, Caleb D.
- You have accessEvaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug TransportersLydia M. M. Vermeer, Caleb D. Isringhausen, Brian W. Ogilvie and David B. BuckleyDrug Metabolism and Disposition March 2016, 44 (3) 453-459; DOI: https://doi.org/10.1124/dmd.115.067744
Iyer, Ramaswamy A.
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
J
Jackson, Tonya
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
Jasper, Paul
- You have accessRapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 CellsHuan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. GiacominiDrug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
Jeong, Hyunyoung
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
Jiang, Yiming
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Jilek, Joseph L.
- You have accessMicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective TherapyAi-Ming Yu, Ye Tian, Mei-Juan Tu, Pui Yan Ho and Joseph L. JilekDrug Metabolism and Disposition March 2016, 44 (3) 308-319; DOI: https://doi.org/10.1124/dmd.115.067470
Johns, Douglas
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
K
Katoh, Miki
- You have accessEffects of Phenobarbital on Expression of UDP-Glucuronosyltransferase 1a6 and 1a7 in Rat BrainYukiko Sakakibara, Miki Katoh, Yuya Kondo and Masayuki NadaiDrug Metabolism and Disposition March 2016, 44 (3) 370-377; DOI: https://doi.org/10.1124/dmd.115.067439
Klaassen, Curtis D.
- You have accessCalorie Restriction Increases P-Glycoprotein and Decreases Intestinal Absorption of Digoxin in MiceHelen J. Renaud, Curtis D. Klaassen and Iván L. CsanakyDrug Metabolism and Disposition March 2016, 44 (3) 366-369; DOI: https://doi.org/10.1124/dmd.115.064766
Kocarek, Thomas A.
- You have accessRole of Phosphatidic Acid Phosphatase Domain Containing 2 in Squalestatin 1–Mediated Activation of the Constitutive Androstane Receptor in Primary Cultured Rat HepatocytesAsmita Pant and Thomas A. KocarekDrug Metabolism and Disposition March 2016, 44 (3) 352-355; DOI: https://doi.org/10.1124/dmd.115.068437
Kole, Prashant
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
Kondo, Yuya
- You have accessEffects of Phenobarbital on Expression of UDP-Glucuronosyltransferase 1a6 and 1a7 in Rat BrainYukiko Sakakibara, Miki Katoh, Yuya Kondo and Masayuki NadaiDrug Metabolism and Disposition March 2016, 44 (3) 370-377; DOI: https://doi.org/10.1124/dmd.115.067439
Kumar, Sanjeev
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
Kurokawa, Takaya
- You have accessArylacetamide Deacetylase is Responsible for Activation of Prasugrel in Human and DogTakaya Kurokawa, Tatsuki Fukami, Tomohiro Yoshida and Miki NakajimaDrug Metabolism and Disposition March 2016, 44 (3) 409-416; DOI: https://doi.org/10.1124/dmd.115.068221
L
Lai, Yurong
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
Lederman, Harmony
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
Leitzman, Pablo
- You have accessDietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its DetoxificationSreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo XingDrug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
Li, Dongshun
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Li, Xi
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Lin, Yvonne S.
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
Liu, Tongtong
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
Liu, Zhongqiu
- You have accessSGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in RatsJian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
Lu, Linlin
- You have accessSGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in RatsJian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
Lutz, Ryan
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
M
Mandlekar, Sandhya
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
Marathe, Punit
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
Martin, Paul
- You have accessSolitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin ExposureRobert Elsby, Paul Martin, Dominic Surry, Pradeep Sharma and Katherine FennerDrug Metabolism and Disposition March 2016, 44 (3) 398-408; DOI: https://doi.org/10.1124/dmd.115.066795
Matta, Murali Krishna
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
Maurer, Tristan S.
- You have accessRapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 CellsHuan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. GiacominiDrug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
Miners, John O.
- You have accessHuman UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme InhibitionAttarat Pattanawongsa, Pramod C. Nair, Andrew Rowland and John O. MinersDrug Metabolism and Disposition March 2016, 44 (3) 378-388; DOI: https://doi.org/10.1124/dmd.115.068213
Mitra, Kaushik
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
Murphy, Sharon E.
- You have accessDietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its DetoxificationSreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo XingDrug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
N
Nadai, Masayuki
- You have accessEffects of Phenobarbital on Expression of UDP-Glucuronosyltransferase 1a6 and 1a7 in Rat BrainYukiko Sakakibara, Miki Katoh, Yuya Kondo and Masayuki NadaiDrug Metabolism and Disposition March 2016, 44 (3) 370-377; DOI: https://doi.org/10.1124/dmd.115.067439
Nair, Pramod C.
- You have accessHuman UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme InhibitionAttarat Pattanawongsa, Pramod C. Nair, Andrew Rowland and John O. MinersDrug Metabolism and Disposition March 2016, 44 (3) 378-388; DOI: https://doi.org/10.1124/dmd.115.068213
Nakajima, Miki
- You have accessArylacetamide Deacetylase is Responsible for Activation of Prasugrel in Human and DogTakaya Kurokawa, Tatsuki Fukami, Tomohiro Yoshida and Miki NakajimaDrug Metabolism and Disposition March 2016, 44 (3) 409-416; DOI: https://doi.org/10.1124/dmd.115.068221
Narayanapillai, Sreekanth C.
- You have accessDietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its DetoxificationSreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo XingDrug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
Neuhoff, Sibylle
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 CellsMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug DispositionMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
Nicolaï, Johan
- You have accessTransport-Metabolism Interplay of Atazanavir in Rat HepatocytesJohan Nicolaï, Tom De Bruyn, Louise Thevelin, Patrick Augustijns and Pieter AnnaertDrug Metabolism and Disposition March 2016, 44 (3) 389-397; DOI: https://doi.org/10.1124/dmd.115.068114
O
Ogilvie, Brian W.
- You have accessEvaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug TransportersLydia M. M. Vermeer, Caleb D. Isringhausen, Brian W. Ogilvie and David B. BuckleyDrug Metabolism and Disposition March 2016, 44 (3) 453-459; DOI: https://doi.org/10.1124/dmd.115.067744
P
Paladino, Jordan
- You have accessDietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its DetoxificationSreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo XingDrug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
Pan, Xian
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
Pant, Asmita
- You have accessRole of Phosphatidic Acid Phosphatase Domain Containing 2 in Squalestatin 1–Mediated Activation of the Constitutive Androstane Receptor in Primary Cultured Rat HepatocytesAsmita Pant and Thomas A. KocarekDrug Metabolism and Disposition March 2016, 44 (3) 352-355; DOI: https://doi.org/10.1124/dmd.115.068437
Patrick, Kennerly S.
- You have accessAbsorption Differences between Immediate-Release Dexmethylphenidate and dl-MethylphenidateKennerly S. Patrick and Arthur B. StraughnDrug Metabolism and Disposition March 2016, 44 (3) 418-421; DOI: https://doi.org/10.1124/dmd.115.067975
Pattanawongsa, Attarat
- You have accessHuman UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme InhibitionAttarat Pattanawongsa, Pramod C. Nair, Andrew Rowland and John O. MinersDrug Metabolism and Disposition March 2016, 44 (3) 378-388; DOI: https://doi.org/10.1124/dmd.115.068213
Prasad, Bhagwat
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
Putluru, Siva Prasad
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
Q
Qin, Xiaoling
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
R
Ramsden, Diane
- You have accessContribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo OutcomesRucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. TweedieDrug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
Renaud, Helen J.
- You have accessCalorie Restriction Increases P-Glycoprotein and Decreases Intestinal Absorption of Digoxin in MiceHelen J. Renaud, Curtis D. Klaassen and Iván L. CsanakyDrug Metabolism and Disposition March 2016, 44 (3) 366-369; DOI: https://doi.org/10.1124/dmd.115.064766
Rodrigues, A. David
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
Rostami-Hodjegan, Amin
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 CellsMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug DispositionMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
Rowland, Andrew
- You have accessHuman UDP-Glucuronosyltransferase (UGT) 2B10: Validation of Cotinine as a Selective Probe Substrate, Inhibition by UGT Enzyme-Selective Inhibitors and Antidepressant and Antipsychotic Drugs, and Structural Determinants of Enzyme InhibitionAttarat Pattanawongsa, Pramod C. Nair, Andrew Rowland and John O. MinersDrug Metabolism and Disposition March 2016, 44 (3) 378-388; DOI: https://doi.org/10.1124/dmd.115.068213
Rowland, Lois
- You have accessContribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo OutcomesRucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. TweedieDrug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
Russell, Matthew R.
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 CellsMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug DispositionMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
S
Sabo, John P.
- You have accessContribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo OutcomesRucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. TweedieDrug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
Sakakibara, Yukiko
- You have accessEffects of Phenobarbital on Expression of UDP-Glucuronosyltransferase 1a6 and 1a7 in Rat BrainYukiko Sakakibara, Miki Katoh, Yuya Kondo and Masayuki NadaiDrug Metabolism and Disposition March 2016, 44 (3) 370-377; DOI: https://doi.org/10.1124/dmd.115.067439
Sane, Rucha S.
- You have accessContribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo OutcomesRucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. TweedieDrug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
Schaefer, Michelle
- You have accessUpcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable CompoundsMichelle Schaefer, Gerhard Schänzle, Daniel Bischoff and Roderich D. SüssmuthDrug Metabolism and Disposition March 2016, 44 (3) 435-444; DOI: https://doi.org/10.1124/dmd.115.067348
Schänzle, Gerhard
- You have accessUpcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable CompoundsMichelle Schaefer, Gerhard Schänzle, Daniel Bischoff and Roderich D. SüssmuthDrug Metabolism and Disposition March 2016, 44 (3) 435-444; DOI: https://doi.org/10.1124/dmd.115.067348
Schuetz, Erin G.
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
Scott, Dennis O.
- You have accessRapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 CellsHuan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. GiacominiDrug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
Sharma, Pradeep
- You have accessSolitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin ExposureRobert Elsby, Paul Martin, Dominic Surry, Pradeep Sharma and Katherine FennerDrug Metabolism and Disposition March 2016, 44 (3) 398-408; DOI: https://doi.org/10.1124/dmd.115.066795
Shen, Xiaolan
- You have accessDisposition into Adipose Tissue Determines Accumulation and Elimination Kinetics of the Cholesteryl Ester Transfer Protein Inhibitor Anacetrapib in MiceGeorgy Hartmann, Sanjeev Kumar, Douglas Johns, Ferdous Gheyas, David Gutstein, Xiaolan Shen, Aimee Burton, Harmony Lederman, Ryan Lutz, Tonya Jackson, Cynthia Chavez-Eng and Kaushik MitraDrug Metabolism and Disposition March 2016, 44 (3) 428-434; DOI: https://doi.org/10.1124/dmd.115.067736
Shi, Jian
- You have accessSGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in RatsJian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
Shireman, Laura M.
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
Straughn, Arthur B.
- You have accessAbsorption Differences between Immediate-Release Dexmethylphenidate and dl-MethylphenidateKennerly S. Patrick and Arthur B. StraughnDrug Metabolism and Disposition March 2016, 44 (3) 418-421; DOI: https://doi.org/10.1124/dmd.115.067975
Surry, Dominic
- You have accessSolitary Inhibition of the Breast Cancer Resistance Protein Efflux Transporter Results in a Clinically Significant Drug-Drug Interaction with Rosuvastatin by Causing up to a 2-Fold Increase in Statin ExposureRobert Elsby, Paul Martin, Dominic Surry, Pradeep Sharma and Katherine FennerDrug Metabolism and Disposition March 2016, 44 (3) 398-408; DOI: https://doi.org/10.1124/dmd.115.066795
Süssmuth, Roderich D.
- You have accessUpcyte Human Hepatocytes: a Potent In Vitro Tool for the Prediction of Hepatic Clearance of Metabolically Stable CompoundsMichelle Schaefer, Gerhard Schänzle, Daniel Bischoff and Roderich D. SüssmuthDrug Metabolism and Disposition March 2016, 44 (3) 435-444; DOI: https://doi.org/10.1124/dmd.115.067348
T
Tan, Huasen
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Tay-Sontheimer, Jessica
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
Thevelin, Louise
- You have accessTransport-Metabolism Interplay of Atazanavir in Rat HepatocytesJohan Nicolaï, Tom De Bruyn, Louise Thevelin, Patrick Augustijns and Pieter AnnaertDrug Metabolism and Disposition March 2016, 44 (3) 389-397; DOI: https://doi.org/10.1124/dmd.115.068114
Thummel, Kenneth E.
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
- You have accessFunctional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass MetabolismYoshiyuki Yamaura, Brian D. Chapron, Zhican Wang, Jonathan Himmelfarb and Kenneth E. ThummelDrug Metabolism and Disposition March 2016, 44 (3) 329-335; DOI: https://doi.org/10.1124/dmd.115.068429
Tian, Ye
- You have accessMicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective TherapyAi-Ming Yu, Ye Tian, Mei-Juan Tu, Pui Yan Ho and Joseph L. JilekDrug Metabolism and Disposition March 2016, 44 (3) 308-319; DOI: https://doi.org/10.1124/dmd.115.067470
Tien, Yun-Chen
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
Ting, Naitee
- You have accessContribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo OutcomesRucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. TweedieDrug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
Tolsma, John
- You have accessRapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 CellsHuan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. GiacominiDrug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
Tracy, Timothy S.
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
Tu, Mei-Juan
- You have accessMicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective TherapyAi-Ming Yu, Ye Tian, Mei-Juan Tu, Pui Yan Ho and Joseph L. JilekDrug Metabolism and Disposition March 2016, 44 (3) 308-319; DOI: https://doi.org/10.1124/dmd.115.067470
Tweedie, Donald J.
- You have accessContribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo OutcomesRucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. TweedieDrug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
U
Upadhyaya, Pramod
- You have accessDietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its DetoxificationSreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo XingDrug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
V
Vermeer, Lydia M. M.
- You have accessEvaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug TransportersLydia M. M. Vermeer, Caleb D. Isringhausen, Brian W. Ogilvie and David B. BuckleyDrug Metabolism and Disposition March 2016, 44 (3) 453-459; DOI: https://doi.org/10.1124/dmd.115.067744
von Weymarn, Linda B.
- You have accessDietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its DetoxificationSreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo XingDrug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
W
Wang, Ying
- You have accessSGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in RatsJian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Wang, Zhican
- You have accessFunctional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass MetabolismYoshiyuki Yamaura, Brian D. Chapron, Zhican Wang, Jonathan Himmelfarb and Kenneth E. ThummelDrug Metabolism and Disposition March 2016, 44 (3) 329-335; DOI: https://doi.org/10.1124/dmd.115.068429
Warhurst, Geoffrey
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-Glycoprotein and Breast Cancer Resistance Protein: Part I: A Cross-Laboratory Comparison of Transporter-Protein Abundances and Relative Expression Factors in Human Intestine and Caco-2 CellsMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 297-307; DOI: https://doi.org/10.1124/dmd.115.067371
- You have accessIn Vitro–In Vivo Extrapolation Scaling Factors for Intestinal P-glycoprotein and Breast Cancer Resistance Protein: Part II. The Impact of Cross-Laboratory Variations of Intestinal Transporter Relative Expression Factors on Predicted Drug DispositionMatthew D. Harwood, Brahim Achour, Sibylle Neuhoff, Matthew R. Russell, Gordon Carlson, Geoffrey Warhurst and Amin Rostami-HodjeganDrug Metabolism and Disposition March 2016, 44 (3) 476-480; DOI: https://doi.org/10.1124/dmd.115.067777
Whitcher-Johnstone, Andrea
- You have accessContribution of Major Metabolites toward Complex Drug-Drug Interactions of Deleobuvir: In Vitro Predictions and In Vivo OutcomesRucha S. Sane, Diane Ramsden, John P. Sabo, Curtis Cooper, Lois Rowland, Naitee Ting, Andrea Whitcher-Johnstone and Donald J. TweedieDrug Metabolism and Disposition March 2016, 44 (3) 466-475; DOI: https://doi.org/10.1124/dmd.115.066985
Wójcikowski, Jacek
- You have accessMelatonin Supports CYP2D-Mediated Serotonin Synthesis in the BrainAnna Haduch, Ewa Bromek, Jacek Wójcikowski, Krystyna Gołembiowska and Władysława A. DanielDrug Metabolism and Disposition March 2016, 44 (3) 445-452; DOI: https://doi.org/10.1124/dmd.115.067413
Wu, Peng
- You have accessSGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in RatsJian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
X
Xing, Chengguo
- You have accessDietary Dihydromethysticin Increases Glucuronidation of 4-(Methylnitrosamino)-1-(3-Pyridyl)-1-Butanol in A/J Mice, Potentially Enhancing Its DetoxificationSreekanth C. Narayanapillai, Linda B. von Weymarn, Steven G. Carmella, Pablo Leitzman, Jordan Paladino, Pramod Upadhyaya, Stephen S. Hecht, Sharon E. Murphy and Chengguo XingDrug Metabolism and Disposition March 2016, 44 (3) 422-427; DOI: https://doi.org/10.1124/dmd.115.068387
Y
Yamaura, Yoshiyuki
- You have accessFunctional Comparison of Human Colonic Carcinoma Cell Lines and Primary Small Intestinal Epithelial Cells for Investigations of Intestinal Drug Permeability and First-Pass MetabolismYoshiyuki Yamaura, Brian D. Chapron, Zhican Wang, Jonathan Himmelfarb and Kenneth E. ThummelDrug Metabolism and Disposition March 2016, 44 (3) 329-335; DOI: https://doi.org/10.1124/dmd.115.068429
Yan, Tongmeng
- You have accessSGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in RatsJian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
Yang, Xin
- You have accessNovel Cytochrome P450 Reaction Phenotyping for Low-Clearance Compounds Using the Hepatocyte Relay MethodXin Yang, Karen Atkinson and Li DiDrug Metabolism and Disposition March 2016, 44 (3) 460-465; DOI: https://doi.org/10.1124/dmd.115.067876
Yang, Zheng
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
Yee, Sook Wah
- You have accessRapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 CellsHuan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. GiacominiDrug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
Yoshida, Tomohiro
- You have accessArylacetamide Deacetylase is Responsible for Activation of Prasugrel in Human and DogTakaya Kurokawa, Tatsuki Fukami, Tomohiro Yoshida and Miki NakajimaDrug Metabolism and Disposition March 2016, 44 (3) 409-416; DOI: https://doi.org/10.1124/dmd.115.068221
Yu, Ai-Ming
- You have accessMicroRNA Pharmacoepigenetics: Posttranscriptional Regulation Mechanisms behind Variable Drug Disposition and Strategy to Develop More Effective TherapyAi-Ming Yu, Ye Tian, Mei-Juan Tu, Pui Yan Ho and Joseph L. JilekDrug Metabolism and Disposition March 2016, 44 (3) 308-319; DOI: https://doi.org/10.1124/dmd.115.067470
Yu, Jia
- You have accessSGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in RatsJian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
Z
Zeng, Hang
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Zeng, Xuezhen
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Zhang, Yueping
- You have accessDiclofenac and Its Acyl Glucuronide: Determination of In Vivo Exposure in Human Subjects and Characterization as Human Drug Transporter Substrates In VitroYueping Zhang, Yong-Hae Han, Siva Prasad Putluru, Murali Krishna Matta, Prashant Kole, Sandhya Mandlekar, Michael T. Furlong, Tongtong Liu, Ramaswamy A. Iyer, Punit Marathe, Zheng Yang, Yurong Lai and A. David RodriguesDrug Metabolism and Disposition March 2016, 44 (3) 320-328; DOI: https://doi.org/10.1124/dmd.115.066944
Zheng, Haihui
- You have accessSGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in RatsJian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
Zhong, Xiao-bo
- You have accessInterindividual Variability in Cytochrome P450–Mediated Drug MetabolismTimothy S. Tracy, Amarjit S. Chaudhry, Bhagwat Prasad, Kenneth E. Thummel, Erin G. Schuetz, Xiao-bo Zhong, Yun-Chen Tien, Hyunyoung Jeong, Xian Pan, Laura M. Shireman, Jessica Tay-Sontheimer and Yvonne S. LinDrug Metabolism and Disposition March 2016, 44 (3) 343-351; DOI: https://doi.org/10.1124/dmd.115.067900
Zhou, Yawen
- You have accessHepatoprotective Effects of Schisandra sphenanthera Extract against Lithocholic Acid–Induced Cholestasis in Male Mice Are Associated with Activation of the Pregnane X Receptor Pathway and Promotion of Liver RegenerationHang Zeng, Dongshun Li, Xiaoling Qin, Pan Chen, Huasen Tan, Xuezhen Zeng, Xi Li, Xiaomei Fan, Yiming Jiang, Yawen Zhou, Yixin Chen, Ying Wang, Min Huang and Huichang BiDrug Metabolism and Disposition March 2016, 44 (3) 337-342; DOI: https://doi.org/10.1124/dmd.115.066969
Zhu, Lijun
- You have accessSGLT-1 Transport and Deglycosylation inside Intestinal Cells Are Key Steps in the Absorption and Disposition of Calycosin-7-O-β-d-Glucoside in RatsJian Shi, Haihui Zheng, Jia Yu, Lijun Zhu, Tongmeng Yan, Peng Wu, Linlin Lu, Ying Wang, Ming Hu and Zhongqiu LiuDrug Metabolism and Disposition March 2016, 44 (3) 283-296; DOI: https://doi.org/10.1124/dmd.115.067009
Zur, Arik A.
- You have accessRapid Method To Determine Intracellular Drug Concentrations in Cellular Uptake Assays: Application to Metformin in Organic Cation Transporter 1–Transfected Human Embryonic Kidney 293 CellsHuan-Chieh Chien, Arik A. Zur, Tristan S. Maurer, Sook Wah Yee, John Tolsma, Paul Jasper, Dennis O. Scott and Kathleen M. GiacominiDrug Metabolism and Disposition March 2016, 44 (3) 356-364; DOI: https://doi.org/10.1124/dmd.115.066647
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