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Research ArticleArticle

Evaluation of Ketoconazole and Its Alternative Clinical CYP3A4/5 Inhibitors as Inhibitors of Drug Transporters: The In Vitro Effects of Ketoconazole, Ritonavir, Clarithromycin, and Itraconazole on 13 Clinically-Relevant Drug Transporters

Lydia M. M. Vermeer, Caleb D. Isringhausen, Brian W. Ogilvie and David B. Buckley
Drug Metabolism and Disposition March 2016, 44 (3) 453-459; DOI: https://doi.org/10.1124/dmd.115.067744

Article Information

vol. 44 no. 3 453-459
DOI 
https://doi.org/10.1124/dmd.115.067744
PubMed 
26668209
Published By 
American Society for Pharmacology and Experimental Therapeutics
Print ISSN 
0090-9556
Online ISSN 
1521-009X
History 
  • Received October 8, 2015
  • Accepted December 11, 2015
  • Published online February 16, 2016.

Article Versions

Copyright & Usage 
Copyright © 2016 by The American Society for Pharmacology and Experimental Therapeutics

Author Information

  1. Lydia M. M. Vermeer1,
  2. Caleb D. Isringhausen1,
  3. Brian W. Ogilvie, and
  4. David B. Buckley
  1. Sekisui XenoTech, LLC Kansas City, Kansas
  1. Address correspondence to:
    Dr. David B. Buckley, Sekisui XenoTech, LLC, 1101 West Cambridge Circle Drive, Kansas City, KS 66103. E-mail: dbuckley{at}xenotechllc.com
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Research ArticleArticle

Effect of Clinical CYP3A4/5 Inhibitors on Drug Transporters

Lydia M. M. Vermeer, Caleb D. Isringhausen, Brian W. Ogilvie and David B. Buckley
Drug Metabolism and Disposition March 1, 2016, 44 (3) 453-459; DOI: https://doi.org/10.1124/dmd.115.067744
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